Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Human T-cell leukemia virus 1 infection 💬
 3件: CD3D, CD3E, CD3G 💬 Otelixizumab 💬 Otelixizumab 1件: 46 💬
2 Human T-cell leukemia virus 1 infection 💬
 3件: CD3D, CD3E, CD3G 💬 Visilizumab 💬 Visilizumab 2件: 96, 97 💬
3 Human T-cell leukemia virus 1 infection 💬
 1件: CD3E 💬 Mosunetuzumab 💬 Mosunetuzumab 1件: 49 💬
4 Human T-cell leukemia virus 1 infection 💬
 1件: CD4 💬 Zanolimumab 💬 Zanolimumab 1件: 46 💬
5 Human T-cell leukemia virus 1 infection 💬
 1件: CD40 💬 Bleselumab 💬 Bleselumab 1件: 222 💬
6 Human T-cell leukemia virus 1 infection 💬
 1件: CD40 💬 Iscalimab 💬 Iscalimab 2件: 49, 53 💬
7 Human T-cell leukemia virus 1 infection 💬
 1件: CD40 💬 Ravagalimab 💬 Ravagalimab 2件: 53, 97 💬
8 Human T-cell leukemia virus 1 infection 💬
 1件: CDK4 💬 Abemaciclib 💬 Abemaciclib 1件: 34 💬
9 Human T-cell leukemia virus 1 infection 💬
 1件: CSF2 💬 Otilimab 💬 Otilimab 1件: 46 💬
10 Human T-cell leukemia virus 1 infection 💬
 1件: FDPS 💬 Alendronic acid 💬 Alendronic acid 7件: 19, 41, 46, 50, 271, 274, 299 💬
11 Human T-cell leukemia virus 1 infection 💬
 1件: FDPS 💬 Pamidronic acid 💬 Pamidronic acid 3件: 270, 271, 274 💬
12 Human T-cell leukemia virus 1 infection 💬
 1件: FDPS 💬 Risedronic acid 💬 Risedronic acid 9件: 46, 50, 66, 93, 95, 96, 107, 113, 274 💬
13 Human T-cell leukemia virus 1 infection 💬
 1件: FDPS 💬 Zoledronic acid 💬 Zoledronic acid 13件:  5 ,  6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
14 Human T-cell leukemia virus 1 infection 💬
 1件: FDPS 💬 Zoledronic acid 💬 Zoledronic acid 13件:  5 ,  6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
15 Human T-cell leukemia virus 1 infection 💬
 2件: IL1R1, IL1R2 💬 Anakinra 💬 Anakinra 18件:  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
16 Human T-cell leukemia virus 1 infection 💬
 1件: IL2RA 💬 Basiliximab 💬 Basiliximab 6件:  2 , 50, 66, 97, 222, 228 💬
17 Human T-cell leukemia virus 1 infection 💬
 1件: IL2RA 💬 Daclizumab 💬 Daclizumab 8件: 13, 56, 60, 65, 97, 107, 283, 284 💬
18 Human T-cell leukemia virus 1 infection 💬
 3件: IL2RA, IL2RB, IL2RG 💬 Aldesleukin 💬 Aldesleukin 6件:  2 , 35, 49, 65, 96, 97 💬
19 Human T-cell leukemia virus 1 infection 💬
 1件: IL6 💬 Olokizumab 💬 Olokizumab 2件: 46, 96 💬
20 Human T-cell leukemia virus 1 infection 💬
 1件: IL6 💬 Siltuximab 💬 Siltuximab 2件: 28, 331 💬
21 Human T-cell leukemia virus 1 infection 💬
 1件: IL6 💬 Sirukumab 💬 Sirukumab 2件: 41, 46 💬
22 Human T-cell leukemia virus 1 infection 💬
 2件: IL6, TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
23 Human T-cell leukemia virus 1 infection 💬
 2件: IL6, TNF 💬 Pomalidomide 💬 Pomalidomide 5件: 28, 51, 85, 227, 331 💬
24 Human T-cell leukemia virus 1 infection 💬
 1件: ITGAL 💬 Efalizumab 💬 Efalizumab 9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
25 Human T-cell leukemia virus 1 infection 💬
 1件: JAK1 💬 Abrocitinib 💬 Abrocitinib 1件: 84 💬
26 Human T-cell leukemia virus 1 infection 💬
 1件: JAK1 💬 Baricitinib 💬 Baricitinib 13件:  2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
27 Human T-cell leukemia virus 1 infection 💬
 1件: JAK1 💬 Filgotinib 💬 Filgotinib 6件: 46, 53, 96, 97, 222, 271 💬
28 Human T-cell leukemia virus 1 infection 💬
 1件: JAK1 💬 Itacitinib 💬 Itacitinib 4件: 46, 51, 97, 228 💬
29 Human T-cell leukemia virus 1 infection 💬
 1件: JAK1 💬 Ruxolitinib 💬 Ruxolitinib 3件: 60, 65, 228 💬
30 Human T-cell leukemia virus 1 infection 💬
 1件: JAK1 💬 Upadacitinib 💬 Upadacitinib 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
31 Human T-cell leukemia virus 1 infection 💬
 2件: JAK1, JAK3 💬 Peficitinib 💬 Peficitinib 1件: 46 💬
32 Human T-cell leukemia virus 1 infection 💬
 2件: JAK1, JAK3 💬 Tofacitinib 💬 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
33 Human T-cell leukemia virus 1 infection 💬
 1件: LCK 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
34 Human T-cell leukemia virus 1 infection 💬
 1件: LCK 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
35 Human T-cell leukemia virus 1 infection 💬
 1件: LTA 💬 Pateclizumab 💬 Pateclizumab 1件: 46 💬
36 Human T-cell leukemia virus 1 infection 💬
 2件: LTA, TNF 💬 Etanercept 💬 Etanercept 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
37 Human T-cell leukemia virus 1 infection 💬
 2件: MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib 1件: 34 💬
38 Human T-cell leukemia virus 1 infection 💬
 2件: MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib 1件: 280 💬
39 Human T-cell leukemia virus 1 infection 💬
 2件: MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib 1件: 34 💬
40 Human T-cell leukemia virus 1 infection 💬
 2件: MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib 1件: 34 💬
41 Human T-cell leukemia virus 1 infection 💬
 2件: MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib 4件:  2 , 34, 279, 280 💬
42 Human T-cell leukemia virus 1 infection 💬
 1件: NFKB1 💬 Iguratimod 💬 Iguratimod 5件: 46, 51, 53, 271, 300 💬
43 Human T-cell leukemia virus 1 infection 💬
 1件: PIK3CA 💬 Alpelisib 💬 Alpelisib 1件: 138 💬
44 Human T-cell leukemia virus 1 infection 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬
45 Human T-cell leukemia virus 1 infection 💬
 1件: PIK3CD 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬
46 Human T-cell leukemia virus 1 infection 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Cyclosporine 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
47 Human T-cell leukemia virus 1 infection 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Pimecrolimus 💬 Pimecrolimus 1件: 160 💬
48 Human T-cell leukemia virus 1 infection 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
49 Human T-cell leukemia virus 1 infection 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
50 Human T-cell leukemia virus 1 infection 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Voclosporin 💬 Voclosporin 2件: 49, 222 💬
51 Human T-cell leukemia virus 1 infection 💬
 1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
52 Human T-cell leukemia virus 1 infection 💬
 3件: TGFB1, TGFB2, TGFB3 💬 Fresolimumab 💬 Fresolimumab 3件: 51, 85, 222 💬
53 Human T-cell leukemia virus 1 infection 💬
 1件: TNF 💬 Adalimumab 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
54 Human T-cell leukemia virus 1 infection 💬
 1件: TNF 💬 Certolizumab pegol 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
55 Human T-cell leukemia virus 1 infection 💬
 1件: TNF 💬 Golimumab 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
56 Human T-cell leukemia virus 1 infection 💬
 1件: TNF 💬 Infliximab 💬 Infliximab 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
57 Human T-cell leukemia virus 1 infection 💬
 1件: TNF 💬 Lenalidomide 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
58 Human T-cell leukemia virus 1 infection 💬
 1件: TNF 💬 Ozoralizumab 💬 Ozoralizumab 1件: 46 💬
59 Human T-cell leukemia virus 1 infection 💬
 1件: TNF 💬 Pegsunercept 💬 Pegsunercept 1件: 46 💬
60 Human T-cell leukemia virus 1 infection 💬
 1件: TNF 💬 Thalidomide 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
61 Human T-cell leukemia virus 1 infection 💬
 1件: TNFRSF13C 💬 Ianalumab 💬 Ianalumab 7件: 35, 46, 49, 53, 61, 63, 95 💬
62 Human T-cell leukemia virus 1 infection 💬
 1件: XPO1 💬 Selinexor 💬 Selinexor 1件: 28 💬