Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Long-term potentiation 💬
1件: BRAF 💬 D10064 💬 Dabrafenib 1件: 34 💬
2 Long-term potentiation 💬
2件: BRAF, RAF1 💬 D06272 💬 Sorafenib 2件: 34, 86 💬
3 Long-term potentiation 💬
2件: BRAF, RAF1 💬 D08524 💬 Sorafenib 2件: 34, 86 💬
4 Long-term potentiation 💬
1件: CACNA1C 💬 D00615 💬 Amlodipine 4件: 13, 51, 67, 298 💬
5 Long-term potentiation 💬
1件: CACNA1C 💬 D02914 💬 Amlodipine 4件: 13, 51, 67, 298 💬
6 Long-term potentiation 💬
1件: CACNA1C 💬 D07450 💬 Amlodipine 4件: 13, 51, 67, 298 💬
7 Long-term potentiation 💬
1件: CACNA1C 💬 D01173 💬 Cilnidipine 1件: 67 💬
8 Long-term potentiation 💬
1件: CACNA1C 💬 D00616 💬 Diltiazem 3件: 51, 58, 86 💬
9 Long-term potentiation 💬
1件: CACNA1C 💬 D03830 💬 Diltiazem 3件: 51, 58, 86 💬
10 Long-term potentiation 💬
1件: CACNA1C 💬 D07845 💬 Diltiazem 3件: 51, 58, 86 💬
11 Long-term potentiation 💬
1件: CACNA1C 💬 D00349 💬 Isradipine 1件:  6  💬
12 Long-term potentiation 💬
1件: CACNA1C 💬 D00617 💬 Nicardipine 2件: 70, 86 💬
13 Long-term potentiation 💬
1件: CACNA1C 💬 D08270 💬 Nicardipine 2件: 70, 86 💬
14 Long-term potentiation 💬
1件: CACNA1C 💬 D00437 💬 Nifedipine 2件: 50, 81 💬
15 Long-term potentiation 💬
1件: CACNA1C 💬 D01908 💬 Nilvadipine 1件: 90 💬
16 Long-term potentiation 💬
1件: CACNA1C 💬 D05442 💬 Perhexiline 2件: 58, 272 💬
17 Long-term potentiation 💬
1件: CACNA1C 💬 D08340 💬 Perhexiline 2件: 58, 272 💬
18 Long-term potentiation 💬
1件: CACNA1C 💬 D08441 💬 Propiverine 1件: 226 💬
19 Long-term potentiation 💬
1件: CACNA1C 💬 D00619 💬 Verapamil 3件: 96, 140, 167 💬
20 Long-term potentiation 💬
1件: CACNA1C 💬 D02356 💬 Verapamil 3件: 96, 140, 167 💬
21 Long-term potentiation 💬
3件: CACNA1C, GRIA1, GRIA2 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
22 Long-term potentiation 💬
2件: GRIA1, GRIA2 💬 D08964 💬 Perampanel 3件:  2 ,  6 , 144 💬
23 Long-term potentiation 💬
2件: GRIA1, GRIA2 💬 D02696 💬 Talampanel 2件:  2 ,  6  💬
24 Long-term potentiation 💬
7件: GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole 9件:  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
25 Long-term potentiation 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D02780 💬 Acamprosate 2件:  6 , 206 💬
26 Long-term potentiation 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07058 💬 Acamprosate 2件:  6 , 206 💬
27 Long-term potentiation 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00777 💬 Amantadine 4件:  6 ,  8 , 13, 127 💬
28 Long-term potentiation 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine 4件:  6 ,  8 , 13, 127 💬
29 Long-term potentiation 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00848 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
30 Long-term potentiation 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
31 Long-term potentiation 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03744 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
32 Long-term potentiation 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07283 💬 Esketamine 3件:  2 ,  4 , 70 💬
33 Long-term potentiation 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00711 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
34 Long-term potentiation 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
35 Long-term potentiation 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D09917 💬 Latrepirdine 1件:  8  💬
36 Long-term potentiation 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D04905 💬 Memantine 7件:  2 ,  6 ,  8 , 13, 49, 127, 205 💬
37 Long-term potentiation 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine 7件:  2 ,  6 ,  8 , 13, 49, 127, 205 💬
38 Long-term potentiation 💬
2件: MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib 1件: 34 💬
39 Long-term potentiation 💬
2件: MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib 1件: 280 💬
40 Long-term potentiation 💬
2件: MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib 1件: 34 💬
41 Long-term potentiation 💬
2件: MAP2K1, MAP2K2 💬 D10175 💬 Trametinib 4件:  2 , 34, 279, 280 💬
42 Long-term potentiation 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
43 Long-term potentiation 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D05480 💬 Pimecrolimus 1件: 160 💬
44 Long-term potentiation 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
45 Long-term potentiation 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
46 Long-term potentiation 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D09033 💬 Voclosporin 1件: 222 💬