Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Shigellosis 💬
1件: BCL2 💬 D10679 💬 Venetoclax 1件: 28 💬
2 Shigellosis 💬
1件: C3 💬 D11613 💬 Pegcetacoplan 3件:  2 , 62, 222 💬
3 Shigellosis 💬
1件: CSF2 💬 D11343 💬 Otilimab 2件: 46, 256 💬
4 Shigellosis 💬
1件: EGFR 💬 D03455 💬 Cetuximab 5件: 34, 51, 86, 89, 331 💬
5 Shigellosis 💬
1件: EGFR 💬 D04023 💬 Erlotinib 1件: 94 💬
6 Shigellosis 💬
1件: EGFR 💬 D07907 💬 Erlotinib 1件: 94 💬
7 Shigellosis 💬
1件: EGFR 💬 D01977 💬 Gefitinib 1件: 75 💬
8 Shigellosis 💬
1件: EGFR 💬 D11251 💬 Icotinib 1件: 34 💬
9 Shigellosis 💬
1件: EGFR 💬 D04024 💬 Lapatinib 3件: 34, 74, 75 💬
10 Shigellosis 💬
1件: EGFR 💬 D08108 💬 Lapatinib 3件: 34, 74, 75 💬
11 Shigellosis 💬
1件: EGFR 💬 D11772 💬 Tesevatinib 1件: 67 💬
12 Shigellosis 💬
1件: IL1B 💬 D09315 💬 Canakinumab 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
13 Shigellosis 💬
1件: IL1B 💬 D09911 💬 Gevokizumab 4件: 41, 50, 56, 269 💬
14 Shigellosis 💬
1件: IL1B 💬 D06635 💬 Rilonacept 4件: 51, 106, 107, 266 💬
15 Shigellosis 💬
2件: IL1B, TNF 💬 D01583 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
16 Shigellosis 💬
1件: IL1R1 💬 D02934 💬 Anakinra 19件:  2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
17 Shigellosis 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod 2件: 113, 222 💬
18 Shigellosis 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod 1件:  8  💬
19 Shigellosis 💬
1件: MTOR 💬 D02714 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
20 Shigellosis 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
21 Shigellosis 💬
1件: MTOR 💬 D06068 💬 Temsirolimus 4件: 13, 34, 89, 331 💬
22 Shigellosis 💬
1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
23 Shigellosis 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
24 Shigellosis 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
25 Shigellosis 💬
3件: PRKCD, PRKCE, PRKCQ 💬 D09671 💬 Sotrastaurin 1件: 97 💬
26 Shigellosis 💬
1件: RELA 💬 D12181 💬 Edasalonexent 1件: 113 💬
27 Shigellosis 💬
2件: ROCK1, ROCK2 💬 D07941 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
28 Shigellosis 💬
1件: ROCK2 💬 D11815 💬 Belumosudil 1件: 51 💬
29 Shigellosis 💬
1件: SRC 💬 D03252 💬 Bosutinib 2件:  2 , 67 💬
30 Shigellosis 💬
1件: SRC 💬 D03658 💬 Dasatinib 2件: 51, 85 💬
31 Shigellosis 💬
1件: SRC 💬 D06414 💬 Dasatinib 2件: 51, 85 💬
32 Shigellosis 💬
1件: SRC 💬 D09664 💬 Saracatinib 3件:  6 , 89, 272 💬
33 Shigellosis 💬
1件: TNF 💬 D02597 💬 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
34 Shigellosis 💬
1件: TNF 💬 D03441 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
35 Shigellosis 💬
1件: TNF 💬 D00742 💬 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
36 Shigellosis 💬
1件: TNF 💬 D04358 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
37 Shigellosis 💬
1件: TNF 💬 D02598 💬 Infliximab 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
38 Shigellosis 💬
1件: TNF 💬 D04687 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
39 Shigellosis 💬
1件: TNF 💬 D09944 💬 Ozoralizumab 1件: 46 💬
40 Shigellosis 💬
1件: TNF 💬 D05393 💬 Pegsunercept 1件: 46 💬
41 Shigellosis 💬
1件: TNF 💬 D08976 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
42 Shigellosis 💬
1件: TNF 💬 D00754 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬