Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Alcoholic liver disease 💬
3件: ADH1A, ADH1B, ADH1C 💬 Fomepizole 💬 Fomepizole 1件: 301 💬 💬
2 Alcoholic liver disease 💬
1件: C3 💬 Pegcetacoplan 💬 Pegcetacoplan 4件:  2 , 61, 62, 222 💬 💬
3 Alcoholic liver disease 💬
1件: C5 💬 Crovalimab 💬 Crovalimab 2件: 62, 109 💬 💬
4 Alcoholic liver disease 💬
1件: C5 💬 Eculizumab 💬 Eculizumab 7件: 11, 13, 14, 61, 62, 109, 222 💬 💬
5 Alcoholic liver disease 💬
1件: C5 💬 Nomacopan 💬 Nomacopan 3件: 62, 109, 162 💬 💬
6 Alcoholic liver disease 💬
1件: C5 💬 Pozelimab 💬 Pozelimab 2件: 11, 62 💬 💬
7 Alcoholic liver disease 💬
1件: C5 💬 Ravulizumab 💬 Ravulizumab 7件:  2 , 11, 13, 50, 62, 66, 109 💬 💬
8 Alcoholic liver disease 💬
1件: C5 💬 Vilobelimab 💬 Vilobelimab 3件: 43, 44, 269 💬 💬
9 Alcoholic liver disease 💬
1件: C5 💬 Zilucoplan 💬 Zilucoplan 3件:  2 , 11, 62 💬 💬
10 Alcoholic liver disease 💬
1件: C5AR1 💬 Avacopan 💬 Avacopan 3件: 43, 44, 222 💬 💬
11 Alcoholic liver disease 💬
3件: CPT1A, CPT1B, CPT1C 💬 Perhexiline 💬 Perhexiline 2件: 58, 272 💬 💬
12 Alcoholic liver disease 💬
13件: IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 Rontalizumab 💬 Rontalizumab 1件: 49 💬 💬
13 Alcoholic liver disease 💬
13件: IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 Sifalimumab 💬 Sifalimumab 1件: 49 💬 💬
14 Alcoholic liver disease 💬
2件: IL12A, IL12B 💬 Ustekinumab 💬 Ustekinumab 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬
15 Alcoholic liver disease 💬
1件: IL17A 💬 Bimekizumab 💬 Bimekizumab 3件: 46, 97, 271 💬 💬
16 Alcoholic liver disease 💬
1件: IL17A 💬 Ixekizumab 💬 Ixekizumab 8件: 36, 37, 46, 107, 160, 162, 269, 271 💬 💬
17 Alcoholic liver disease 💬
1件: IL17A 💬 Secukinumab 💬 Secukinumab 8件: 13, 37, 41, 46, 107, 160, 269, 271 💬 💬
18 Alcoholic liver disease 💬
1件: IL17A 💬 Tibulizumab 💬 Tibulizumab 1件: 53 💬 💬
19 Alcoholic liver disease 💬
1件: IL17RA 💬 Brodalumab 💬 Brodalumab 2件: 37, 51 💬 💬
20 Alcoholic liver disease 💬
1件: IL1B 💬 Canakinumab 💬 Canakinumab 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬
21 Alcoholic liver disease 💬
1件: IL1B 💬 Gevokizumab 💬 Gevokizumab 4件: 41, 50, 56, 269 💬 💬
22 Alcoholic liver disease 💬
1件: IL1B 💬 Rilonacept 💬 Rilonacept 4件: 51, 106, 107, 266 💬 💬
23 Alcoholic liver disease 💬
3件: IL1B, IL6, TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬
24 Alcoholic liver disease 💬
1件: IL6 💬 Olokizumab 💬 Olokizumab 2件: 46, 96 💬 💬
25 Alcoholic liver disease 💬
1件: IL6 💬 Siltuximab 💬 Siltuximab 2件: 28, 331 💬 💬
26 Alcoholic liver disease 💬
1件: IL6 💬 Sirukumab 💬 Sirukumab 2件: 41, 46 💬 💬
27 Alcoholic liver disease 💬
2件: IL6, TNF 💬 Pomalidomide 💬 Pomalidomide 5件: 28, 51, 85, 227, 331 💬 💬
28 Alcoholic liver disease 💬
1件: MAP3K5 💬 Selonsertib 💬 Selonsertib 1件: 86 💬 💬
29 Alcoholic liver disease 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 Losmapimod 💬 Losmapimod 2件: 113, 222 💬 💬
30 Alcoholic liver disease 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 Neflamapimod 💬 Neflamapimod 1件:  8  💬 💬
31 Alcoholic liver disease 💬
1件: NFKB1 💬 Iguratimod 💬 Iguratimod 5件: 46, 51, 53, 271, 300 💬 💬
32 Alcoholic liver disease 💬
1件: PPARA 💬 Bezafibrate 💬 Bezafibrate 7件: 20, 93, 94, 160, 296, 316, 324 💬 💬
33 Alcoholic liver disease 💬
1件: PPARA 💬 Elafibranor 💬 Elafibranor 2件: 93, 94 💬 💬
34 Alcoholic liver disease 💬
1件: PPARA 💬 Fenofibrate 💬 Fenofibrate 6件:  8 , 79, 93, 94, 97, 265 💬 💬
35 Alcoholic liver disease 💬
1件: PPARA 💬 Pemafibrate 💬 Pemafibrate 1件: 93 💬 💬
36 Alcoholic liver disease 💬
2件: PRKAA1, PRKAA2 💬 Metformin 💬 Metformin 25件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬
37 Alcoholic liver disease 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬 💬
38 Alcoholic liver disease 💬
1件: TNF 💬 Adalimumab 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬
39 Alcoholic liver disease 💬
1件: TNF 💬 Certolizumab pegol 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬 💬
40 Alcoholic liver disease 💬
1件: TNF 💬 Etanercept 💬 Etanercept 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 💬
41 Alcoholic liver disease 💬
1件: TNF 💬 Golimumab 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬
42 Alcoholic liver disease 💬
1件: TNF 💬 Infliximab 💬 Infliximab 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬
43 Alcoholic liver disease 💬
1件: TNF 💬 Lenalidomide 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬 💬
44 Alcoholic liver disease 💬
1件: TNF 💬 Ozoralizumab 💬 Ozoralizumab 1件: 46 💬 💬
45 Alcoholic liver disease 💬
1件: TNF 💬 Pegsunercept 💬 Pegsunercept 1件: 46 💬 💬
46 Alcoholic liver disease 💬
1件: TNF 💬 Thalidomide 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬