Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1Phentermine
(D05458)		[1] Phentermine[1] Phentermine (D05458) 💬[5] MAOA,
MAOB,
SLC6A2,
SLC6A3,
SLC6A4 💬		[16] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Phenylalanine metabolism, Serotonergic synapse, Synaptic vesicle cycle, Tryptophan metabolism, Tyrosine metabolism 💬[1] 97 💬
2Phentermine-Topiramate
(D05458)		[2] Phentermine,
Topiramate		[2] Topiramate ,
Phentermine (D05458) 💬		[41] CA2,
CA4,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ,
GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
MAOA,
MAOB,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A,
SLC6A2,
SLC6A3,
SLC6A4 💬		[63] Adrenergic signaling in cardiomyocytes, Alcoholism, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Arginine and proline metabolism, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, Drug metabolism - cytochrome P450, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, Glycine, serine and threonine metabolism, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Histidine metabolism, Huntington disease, Hypertrophic cardiomyopathy, Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Phenylalanine metabolism, Prion disease, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Synaptic vesicle cycle, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Tryptophan metabolism, Type II diabetes mellitus, Tyrosine metabolism, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 97 💬