Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 2,4-thiazolidinedione [1] Thiazolidinedione---[1] 20
2 Acetylcysteine [3] Acetylcysteine; Mucomyst; N-acetylcysteine[1] D00221 --[21] 6, 13, 19, 20, 21, 49, 51, 53, 58, 63, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337
3 Alemtuzumab [4] Alemtuzumab; Campath; Lemtrada; MABCAMPATH[1] D02802 [1] CD52 💬-[22] 13, 15, 19, 20, 36, 43, 44, 46, 49, 51, 60, 62, 63, 65, 85, 96, 164, 234, 283, 284, 285, 326
4 Bezafibrate [1] BEZAFIBRATE[1] D01366 [1] PPARA 💬[10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[7] 20, 93, 94, 160, 296, 316, 324
5 Biotin [4] BIOTIN; Biotina; D-BIOTIN; Vitamin B7[1] D00029 --[5] 2, 8, 10, 13, 20
6 Busulfan [3] Busilvex; BUSULFAN; BUSULFANO[1] D00248 --[13] 19, 20, 28, 36, 49, 51, 60, 65, 164, 274, 284, 285, 326
7 Chenodeoxycholic acid [3] CDCA; Chenodeoxycholic acid; Chenodiol[1] D00163 [1] NR1H4 💬[1] Bile secretion 💬[4] 20, 96, 234, 263
8 Cholecalciferol [5] CHOLECALCIFEROL; COLECALCIFEROL; Multivitamin; Vitamin D; Vitamin D3[1] D00188 [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[24] 6, 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299
9 Cholic Acid [1] Cholic Acid[1] D10699 [1] NR1H4 💬[1] Bile secretion 💬[4] 20, 234, 265, 310
10 Clofarabine [1] Clofarabine[1] D03546 [3] POLA1,
POLA2,
RRM1 💬		[7] DNA replication, Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬[5] 19, 20, 60, 234, 326
11 Cyclophosphamide [6] Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamidum; Cytoxan[2] D00287 ,
D07760 		--[44] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331
12 Cyclosporine [10] CICLOSPORIN; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A; Ikervis; Neoral; Restasis[1] D00184 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
13 Elivaldogene autotemcel [1] Elivaldogene autotemcel[1] D12150 [1] ABCD1 💬[2] ABC transporters, Peroxisome 💬[1] 20
14 Glyceryl Trierucate [1] Glyceryl Trierucate---[1] 20
15 Glyceryl Trioleate [1] Glyceryl Trioleate---[1] 20
16 Human interferon beta [3] Human interferon beta; Interferon beta; Interferon-Beta---[6] 13, 20, 26, 50, 96, 97
17 Hydroxyurea [1] Hydroxyurea[1] D00341 [1] RRM2 💬[7] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬[8] 3, 13, 19, 20, 65, 85, 86, 284
18 Imidacloprid [0] ---[5] 19, 20, 125, 234, 326
19 Leriglitazone [1] Leriglitazone[1] D11603 [1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[1] 20
20 Lipoic acid [3] Alpha Lipoic Acid; ALPHA-LIPOIC ACID; Lipoic acid---[5] 2, 5, 13, 14, 20
21 Melphalan [3] ALKERAN; MELPHALAN; Melphalan Hydrochloride[1] D00369 --[15] 11, 13, 14, 19, 20, 28, 60, 62, 65, 96, 164, 234, 284, 285, 299
22 Mycophenolate mofetil [3] CELLCEPT; Mycophenolate mofetil; Mycophenolate mofetil TEVA[1] D00752 [2] IMPDH1,
IMPDH2 💬		[4] Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬[34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
23 Mycophenolic acid [5] Acido Micofenolico; MICOFENOLICO ACIDO; Mycophenolate; Mycophenolic acid; Myfortic[1] D05096 [2] IMPDH1,
IMPDH2 💬		[4] Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬[36] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300
24 Pioglitazone [1] Pioglitazone[1] D08378 [1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
25 Plerixafor [2] Mozobil; PLERIXAFOR[1] D08971 [1] CXCR4 💬[14] Axon guidance, Calcium signaling pathway, Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Intestinal immune network for IgA production, Leukocyte transendothelial migration, Pathways in cancer, Regulation of actin cytoskeleton, Viral life cycle - HIV-1, Viral protein interaction with cytokine and cytokine receptor, Virion - Human immunodeficiency virus 💬[5] 19, 20, 65, 285, 299
26 Pramipexole [7] Mirapex; Mirapex ER; Mirapexin; Pramipexol; Pramipexole; PRAMIPEXOLE DIHYDROCHLORIDE; SIFROL[1] D05575 [3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 2, 6, 20
27 Sobetirome [1] Sobetirome[1] D09381 [1] THRB 💬[2] Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬[1] 20
28 Thalidomide [1] Thalidomide[1] D00754 [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[20] 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331
29 Thiotepa [1] Thiotepa[1] D00583 --[12] 13, 19, 20, 28, 51, 60, 65, 85, 96, 164, 284, 285
30 Ursodeoxycholic acid [4] UDCA; Ursodeoxycholic Acid; Ursodiol; Ursofalk[1] D00734 [1] NR1H4 💬[1] Bile secretion 💬[14] 6, 8, 20, 46, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299
31 Vitamin E [2] Alpha-tocopherol; Vitamin E[1] D02331 --[12] 2, 6, 13, 20, 46, 49, 90, 96, 97, 206, 299, 317