Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 TUBB3 [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D00491 Paclitaxel [2] 46, 85
2 TUBB3 [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D00570 Colchicine [7] 2, 42, 46, 56, 93, 210, 266
3 TUBB3 [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D08675 Vinblastine [2] 34, 65
4 TUBB3 [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D08679 Vincristine [4] 26, 34, 65, 331
5 TUBB3 [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D09587 Brentuximab vedotin [2] 49, 51
6 TUBB3 [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D11595 Belantamab mafodotin [1] 28
7 TUBB4A [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D00491 Paclitaxel [2] 46, 85
8 TUBB4A [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D00570 Colchicine [7] 2, 42, 46, 56, 93, 210, 266
9 TUBB4A [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D08675 Vinblastine [2] 34, 65
10 TUBB4A [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D08679 Vincristine [4] 26, 34, 65, 331
11 TUBB4A [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D09587 Brentuximab vedotin [2] 49, 51
12 TUBB4A [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D11595 Belantamab mafodotin [1] 28
13 TUBB4B [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D00491 Paclitaxel [2] 46, 85
14 TUBB4B [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D00570 Colchicine [7] 2, 42, 46, 56, 93, 210, 266
15 TUBB4B [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D08675 Vinblastine [2] 34, 65
16 TUBB4B [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D08679 Vincristine [4] 26, 34, 65, 331
17 TUBB4B [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D09587 Brentuximab vedotin [2] 49, 51
18 TUBB4B [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D11595 Belantamab mafodotin [1] 28
19 MAPK14 [27] Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Relaxin signaling pathway, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D09639 Losmapimod [2] 113, 222
20 MAPK14 [27] Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Relaxin signaling pathway, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D10959 Neflamapimod [1] 8
21 TUBB [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D00491 Paclitaxel [2] 46, 85
22 TUBB [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D00570 Colchicine [7] 2, 42, 46, 56, 93, 210, 266
23 TUBB [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D08675 Vinblastine [2] 34, 65
24 TUBB [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D08679 Vincristine [4] 26, 34, 65, 331
25 TUBB [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D09587 Brentuximab vedotin [2] 49, 51
26 TUBB [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D11595 Belantamab mafodotin [1] 28
27 F2 [5] Phospholipase D signaling pathway, Platelet activation, Regulation of actin cytoskeleton, Pathogenic Escherichia coli infection, Pathways in cancer D06410 Thrombomodulin Alfa [1] 85
28 F2 [5] Phospholipase D signaling pathway, Platelet activation, Regulation of actin cytoskeleton, Pathogenic Escherichia coli infection, Pathways in cancer D07144 Dabigatran etexilate [2] 51, 75
29 F2 [5] Phospholipase D signaling pathway, Platelet activation, Regulation of actin cytoskeleton, Pathogenic Escherichia coli infection, Pathways in cancer D09707 Dabigatran [5] 51, 75, 85, 91, 124
30 FYN [7] Sphingolipid signaling pathway, Phospholipase D signaling pathway, Platelet activation, T cell receptor signaling pathway, Prion disease, Pathogenic Escherichia coli infection, Viral myocarditis D03658 Dasatinib [2] 51, 85
31 FYN [7] Sphingolipid signaling pathway, Phospholipase D signaling pathway, Platelet activation, T cell receptor signaling pathway, Prion disease, Pathogenic Escherichia coli infection, Viral myocarditis D06414 Dasatinib [2] 51, 85
32 ABL1 [4] Ras signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Viral myocarditis D03252 Bosutinib [2] 2, 67
33 ABL1 [4] Ras signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Viral myocarditis D03658 Dasatinib [2] 51, 85
34 ABL1 [4] Ras signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Viral myocarditis D06414 Dasatinib [2] 51, 85
35 ABL1 [4] Ras signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Viral myocarditis D08066 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
36 ABL1 [4] Ras signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Viral myocarditis D08953 Nilotinib [5] 6, 8, 34, 51, 86
37 ABL1 [4] Ras signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Viral myocarditis D09664 Saracatinib [3] 6, 89, 272
38 TUBB8 [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D00491 Paclitaxel [2] 46, 85
39 TUBB8 [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D00570 Colchicine [7] 2, 42, 46, 56, 93, 210, 266
40 TUBB8 [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D08675 Vinblastine [2] 34, 65
41 TUBB8 [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D08679 Vincristine [4] 26, 34, 65, 331
42 TUBB8 [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D09587 Brentuximab vedotin [2] 49, 51
43 TUBB8 [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D11595 Belantamab mafodotin [1] 28
44 TUBB2B [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D00491 Paclitaxel [2] 46, 85
45 TUBB2B [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D00570 Colchicine [7] 2, 42, 46, 56, 93, 210, 266
46 TUBB2B [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D08675 Vinblastine [2] 34, 65
47 TUBB2B [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D08679 Vincristine [4] 26, 34, 65, 331
48 TUBB2B [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D09587 Brentuximab vedotin [2] 49, 51
49 TUBB2B [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D11595 Belantamab mafodotin [1] 28
50 IL1B [13] Toll-like receptor signaling pathway, Th17 cell differentiation, TNF signaling pathway, Type I diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Tuberculosis, Rheumatoid arthritis D01583 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
51 IL1B [13] Toll-like receptor signaling pathway, Th17 cell differentiation, TNF signaling pathway, Type I diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Tuberculosis, Rheumatoid arthritis D06635 Rilonacept [4] 51, 106, 107, 266
52 IL1B [13] Toll-like receptor signaling pathway, Th17 cell differentiation, TNF signaling pathway, Type I diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Tuberculosis, Rheumatoid arthritis D09315 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269
53 IL1B [13] Toll-like receptor signaling pathway, Th17 cell differentiation, TNF signaling pathway, Type I diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Tuberculosis, Rheumatoid arthritis D09911 Gevokizumab [4] 41, 50, 56, 269
54 IL1R1 [3] Th17 cell differentiation, Pathogenic Escherichia coli infection, Shigellosis D02934 Anakinra [18] 2, 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299
55 IL6 [15] Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, Th17 cell differentiation, TNF signaling pathway, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection, Pertussis, Yersinia infection, Tuberculosis, Pathways in cancer, Transcriptional misregulation in cancer, Rheumatoid arthritis D01583 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
56 IL6 [15] Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, Th17 cell differentiation, TNF signaling pathway, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection, Pertussis, Yersinia infection, Tuberculosis, Pathways in cancer, Transcriptional misregulation in cancer, Rheumatoid arthritis D08976 Pomalidomide [5] 28, 51, 85, 227, 331
57 IL6 [15] Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, Th17 cell differentiation, TNF signaling pathway, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection, Pertussis, Yersinia infection, Tuberculosis, Pathways in cancer, Transcriptional misregulation in cancer, Rheumatoid arthritis D09669 Siltuximab [2] 28, 331
58 IL6 [15] Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, Th17 cell differentiation, TNF signaling pathway, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection, Pertussis, Yersinia infection, Tuberculosis, Pathways in cancer, Transcriptional misregulation in cancer, Rheumatoid arthritis D10080 Sirukumab [2] 41, 46
59 IL6 [15] Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, Th17 cell differentiation, TNF signaling pathway, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection, Pertussis, Yersinia infection, Tuberculosis, Pathways in cancer, Transcriptional misregulation in cancer, Rheumatoid arthritis D12487 Olokizumab [2] 46, 96
60 NFKB1 [25] Ras signaling pathway, Sphingolipid signaling pathway, PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Prolactin signaling pathway, Relaxin signaling pathway, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Pathways in cancer, Transcriptional misregulation in cancer, Viral carcinogenesis, Prostate cancer, Small cell lung cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D01146 Iguratimod [5] 46, 51, 53, 271, 300
61 MAPK11 [27] Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Relaxin signaling pathway, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D09639 Losmapimod [2] 113, 222
62 MAPK11 [27] Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Relaxin signaling pathway, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D10959 Neflamapimod [1] 8
63 MAPK13 [27] Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Relaxin signaling pathway, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D09639 Losmapimod [2] 113, 222
64 MAPK13 [27] Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Relaxin signaling pathway, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D10959 Neflamapimod [1] 8
65 RELA [25] Ras signaling pathway, Sphingolipid signaling pathway, PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Prolactin signaling pathway, Relaxin signaling pathway, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Pathways in cancer, Transcriptional misregulation in cancer, Viral carcinogenesis, Prostate cancer, Small cell lung cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D12181 Edasalonexent [1] 113
66 ROCK1 [11] Sphingolipid signaling pathway, Vascular smooth muscle contraction, TGF-beta signaling pathway, Tight junction, Platelet activation, Regulation of actin cytoskeleton, Pathogenic Escherichia coli infection, Shigellosis, Yersinia infection, Pathways in cancer, Proteoglycans in cancer D07941 Fasudil [4] 2, 5, 7, 51
67 MAPK12 [27] Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Relaxin signaling pathway, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D09639 Losmapimod [2] 113, 222
68 MAPK12 [27] Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Relaxin signaling pathway, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D10959 Neflamapimod [1] 8
69 SRC [14] Rap1 signaling pathway, VEGF signaling pathway, Tight junction, Platelet activation, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Pathogenic Escherichia coli infection, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis, Proteoglycans in cancer D03252 Bosutinib [2] 2, 67
70 SRC [14] Rap1 signaling pathway, VEGF signaling pathway, Tight junction, Platelet activation, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Pathogenic Escherichia coli infection, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis, Proteoglycans in cancer D03658 Dasatinib [2] 51, 85
71 SRC [14] Rap1 signaling pathway, VEGF signaling pathway, Tight junction, Platelet activation, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Pathogenic Escherichia coli infection, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis, Proteoglycans in cancer D06414 Dasatinib [2] 51, 85
72 SRC [14] Rap1 signaling pathway, VEGF signaling pathway, Tight junction, Platelet activation, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Pathogenic Escherichia coli infection, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis, Proteoglycans in cancer D09664 Saracatinib [3] 6, 89, 272
73 TNF [21] Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D00742 Etanercept [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285
74 TNF [21] Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D00754 Thalidomide [20] 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331
75 TNF [21] Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D01583 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
76 TNF [21] Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D02597 Adalimumab [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271
77 TNF [21] Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D02598 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271
78 TNF [21] Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D03441 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271
79 TNF [21] Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D04358 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271
80 TNF [21] Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D04687 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331
81 TNF [21] Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D05393 Pegsunercept [1] 46
82 TNF [21] Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D08976 Pomalidomide [5] 28, 51, 85, 227, 331
83 TNF [21] Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D09944 Ozoralizumab [1] 46
84 TUBB2A [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D00491 Paclitaxel [2] 46, 85
85 TUBB2A [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D00570 Colchicine [7] 2, 42, 46, 56, 93, 210, 266
86 TUBB2A [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D08675 Vinblastine [2] 34, 65
87 TUBB2A [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D08679 Vincristine [4] 26, 34, 65, 331
88 TUBB2A [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D09587 Brentuximab vedotin [2] 49, 51
89 TUBB2A [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D11595 Belantamab mafodotin [1] 28
90 TUBB1 [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D00491 Paclitaxel [2] 46, 85
91 TUBB1 [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D00570 Colchicine [7] 2, 42, 46, 56, 93, 210, 266
92 TUBB1 [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D08675 Vinblastine [2] 34, 65
93 TUBB1 [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D08679 Vincristine [4] 26, 34, 65, 331
94 TUBB1 [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D09587 Brentuximab vedotin [2] 49, 51
95 TUBB1 [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D11595 Belantamab mafodotin [1] 28
96 CASP9 [13] Platinum drug resistance, PI3K-Akt signaling pathway, VEGF signaling pathway, Thyroid hormone signaling pathway, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Toxoplasmosis, Tuberculosis, Pathways in cancer, Prostate cancer, Small cell lung cancer, Viral myocarditis D11195 Rimiducid [6] 19, 60, 65, 284, 285, 326
97 TUBB6 [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D00491 Paclitaxel [2] 46, 85
98 TUBB6 [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D00570 Colchicine [7] 2, 42, 46, 56, 93, 210, 266
99 TUBB6 [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D08675 Vinblastine [2] 34, 65
100 TUBB6 [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D08679 Vincristine [4] 26, 34, 65, 331
101 TUBB6 [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D09587 Brentuximab vedotin [2] 49, 51
102 TUBB6 [5] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection D11595 Belantamab mafodotin [1] 28
103 ROCK2 [12] Sphingolipid signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway, Tight junction, Platelet activation, Regulation of actin cytoskeleton, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Yersinia infection, Pathways in cancer, Proteoglycans in cancer D07941 Fasudil [4] 2, 5, 7, 51
104 ROCK2 [12] Sphingolipid signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway, Tight junction, Platelet activation, Regulation of actin cytoskeleton, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Yersinia infection, Pathways in cancer, Proteoglycans in cancer D11815 Belumosudil [2] 51, 85