Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADORA1 [2] ADORA1, ADORA3 💬 |
D00045 D00045 💬 |
Adenosine | 013 [3] 13, 58, 65 💬 |
2 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADORA1 [2] ADORA1, ADORA3 💬 |
D02769 D02769 💬 |
Adenosine phosphate | 046 [1] 46 💬 |
3 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADORA1 [4] ADORA1, PDE2A, PDE3A, PDE3B 💬 |
D00227 D00227 💬 |
Aminophylline | 063 [1] 63 💬 |
4 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADORA1 [4] ADORA1, PDE2A, PDE3A, PDE3B 💬 |
D05429 D05429 💬 |
Aminophylline | 063 [1] 63 💬 |
5 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADORA1 [4] ADORA1, PDE2A, PDE3A, PDE3B 💬 |
D00371 D00371 💬 |
Theophylline | 236 [2] 236, 299 💬 |
6 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADORA1 [4] ADORA1, PDE2A, PDE3A, PDE3B 💬 |
D01712 D01712 💬 |
Theophylline | 236 [2] 236, 299 💬 |
7 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADORA1 [4] ADORA1, PDE2A, PDE3A, PDE3B 💬 |
D02017 D02017 💬 |
Theophylline | 236 [2] 236, 299 💬 |
8 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADORA1 [4] ADORA1, PDE2A, PDE3A, PDE3B 💬 |
D06103 D06103 💬 |
Theophylline | 236 [2] 236, 299 💬 |
9 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADORA1 [4] ADORA1, PDE2A, PDE3A, PDE3B 💬 |
D06104 D06104 💬 |
Theophylline | 236 [2] 236, 299 💬 |
10 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADORA1 [5] ADORA1, PDE2A, PDE3A, PDE3B, PDE5A 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
11 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADORA1 [5] ADORA1, PDE2A, PDE3A, PDE3B, PDE5A 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
12 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADORA3 [1] ADORA3 💬 |
D10971 D10971 💬 |
Piclidenoson | 046 [1] 46 💬 |
13 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D01692 D01692 💬 |
Alfuzosin | 013 [1] 13 💬 |
14 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D07124 D07124 💬 |
Alfuzosin | 013 [1] 13 💬 |
15 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D01965 D01965 💬 |
Silodosin | 006 [2] 6 , 13 💬 |
16 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D00608 D00608 💬 |
Doxazosin | 057 [2] 57, 67 💬 |
17 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D07874 D07874 💬 |
Doxazosin | 057 [2] 57, 67 💬 |
18 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D08064 D08064 💬 |
Ifenprodil | 085 [1] 85 💬 |
19 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D01307 D01307 💬 |
Midodrine | 006 [3] 6 , 17, 58 💬 |
20 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D08220 D08220 💬 |
Midodrine | 006 [3] 6 , 17, 58 💬 |
21 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D00454 D00454 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
22 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D06623 D06623 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
23 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D00511 D00511 💬 |
Phenylephrine | 022 [1] 22 💬 |
24 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D08365 D08365 💬 |
Phenylephrine | 022 [1] 22 💬 |
25 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D00610 D00610 💬 |
Terazosin | 006 [1] 6 💬 |
26 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D08569 D08569 💬 |
Terazosin | 006 [1] 6 💬 |
27 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C 💬 |
D02268 D02268 💬 |
Ergoloid mesylate | 006 [2] 6 , 206 💬 |
28 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C 💬 |
D00680 D00680 💬 |
Methylergometrine | 118 [3] 118, 280, 288 💬 |
29 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C 💬 |
D08207 D08207 💬 |
Methylergometrine | 118 [3] 118, 280, 288 💬 |
30 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
D02349 D02349 💬 |
Dipivefrin | 006 [1] 6 💬 |
31 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
D01277 D01277 💬 |
Droxidopa | 005 [5] 5 , 6 , 17, 169, 170 💬 |
32 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
D00124 D00124 💬 |
Ephedrine | 011 [1] 11 💬 |
33 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
D00095 D00095 💬 |
Epinephrine | 046 [3] 46, 70, 96 💬 |
34 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
D00996 D00996 💬 |
Epinephrine | 046 [3] 46, 70, 96 💬 |
35 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
D02149 D02149 💬 |
Epinephrine | 046 [3] 46, 70, 96 💬 |
36 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
D00076 D00076 💬 |
Norepinephrine | 022 [1] 22 💬 |
37 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
D05206 D05206 💬 |
Norepinephrine | 022 [1] 22 💬 |
38 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
D00485 D00485 💬 |
Pseudoephedrine | 017 [1] 17 💬 |
39 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
D05648 D05648 💬 |
Pseudoephedrine | 017 [1] 17 💬 |
40 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
D05649 D05649 💬 |
Pseudoephedrine | 017 [1] 17 💬 |
41 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
D08449 D08449 💬 |
Pseudoephedrine | 017 [1] 17 💬 |
42 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D00255 D00255 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
43 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D03415 D03415 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
44 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, KCNJ8 💬 |
D00636 D00636 💬 |
Amiodarone | 028 [2] 28, 127 💬 |
45 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, KCNJ8 💬 |
D02910 D02910 💬 |
Amiodarone | 028 [2] 28, 127 💬 |
46 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [1] ADRA2A 💬 |
D00606 D00606 💬 |
Guanfacine | 193 [1] 193 💬 |
47 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [1] ADRA2A 💬 |
D08031 D08031 💬 |
Guanfacine | 193 [1] 193 💬 |
48 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [1] ADRA2A 💬 |
D00560 D00560 💬 |
Pimozide | 002 [1] 2 💬 |
49 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D01008 D01008 💬 |
Apraclonidine | 011 [1] 11 💬 |
50 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D07461 D07461 💬 |
Apraclonidine | 011 [1] 11 💬 |
51 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D02076 D02076 💬 |
Brimonidine | 013 [2] 13, 90 💬 |
52 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D07540 D07540 💬 |
Brimonidine | 013 [2] 13, 90 💬 |
53 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 [1] 254 💬 |
54 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D00789 D00789 💬 |
Chlorpromazine | 254 [1] 254 💬 |
55 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D03274 D03274 💬 |
Chlorpromazine | 254 [1] 254 💬 |
56 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D04034 D04034 💬 |
Chlorpromazine | 254 [1] 254 💬 |
57 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D00281 D00281 💬 |
Clonidine | 006 [4] 6 , 65, 70, 78 💬 |
58 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D00604 D00604 💬 |
Clonidine | 006 [4] 6 , 65, 70, 78 💬 |
59 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D00283 D00283 💬 |
Clozapine | 006 [1] 6 💬 |
60 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D00514 D00514 💬 |
Dexmedetomidine | 002 [13] 2 , 4 , 6 , 21, 34, 46, 70, 107, 113, 212, 215, 226, 280 💬 |
61 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D01205 D01205 💬 |
Dexmedetomidine | 002 [13] 2 , 4 , 6 , 21, 34, 46, 70, 107, 113, 212, 215, 226, 280 💬 |
62 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D04375 D04375 💬 |
Guanabenz | 002 [2] 2 , 13 💬 |
63 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D00405 D00405 💬 |
Methyldopa | 323 [1] 323 💬 |
64 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D08205 D08205 💬 |
Methyldopa | 323 [1] 323 💬 |
65 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D08482 D08482 💬 |
Rilmenidine | 008 [1] 8 💬 |
66 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D00776 D00776 💬 |
Tizanidine | 013 [1] 13 💬 |
67 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D08611 D08611 💬 |
Tizanidine | 013 [1] 13 💬 |
68 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D08685 D08685 💬 |
Yohimbine | 006 [1] 6 💬 |
69 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00235 D00235 💬 |
Atenolol | 167 [1] 167 💬 |
70 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00634 D00634 💬 |
Bisoprolol | 067 [3] 67, 86, 113 💬 |
71 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D02342 D02342 💬 |
Bisoprolol | 067 [3] 67, 86, 113 💬 |
72 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D07660 D07660 💬 |
Celiprolol | 168 [1] 168 💬 |
73 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00632 D00632 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
74 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
75 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03880 D03880 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
76 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03881 D03881 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
77 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00644 D00644 💬 |
Esmolol | 058 [1] 58 💬 |
78 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D07916 D07916 💬 |
Esmolol | 058 [1] 58 💬 |
79 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00601 D00601 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
80 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
81 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05011 D05011 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
82 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05127 D05127 💬 |
Nebivolol | 017 [4] 17, 85, 113, 167 💬 |
83 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00432 D00432 💬 |
Nadolol | 006 [1] 6 💬 |
84 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00378 D00378 💬 |
Timolol | 157 [2] 157, 227 💬 |
85 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00603 D00603 💬 |
Timolol | 157 [2] 157, 227 💬 |
86 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D08600 D08600 💬 |
Timolol | 157 [2] 157, 227 💬 |
87 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D00483 D00483 💬 |
Propranolol | 006 [7] 6 , 158, 167, 215, 227, 278, 296 💬 |
88 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D08443 D08443 💬 |
Propranolol | 006 [7] 6 , 158, 167, 215, 227, 278, 296 💬 |
89 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D07713 D07713 💬 |
Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬 |
90 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D01373 D01373 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
91 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D05277 D05277 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
92 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D07990 D07990 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
93 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D08092 D08092 💬 |
Isoxsuprine | 013 [1] 13 💬 |
94 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D08124 D08124 💬 |
Levosalbutamol | 049 [1] 49 💬 |
95 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 [14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬 |
96 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D00687 D00687 💬 |
Salmeterol | 299 [1] 299 💬 |
97 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D05792 D05792 💬 |
Salmeterol | 299 [1] 299 💬 |
98 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D00688 D00688 💬 |
Terbutaline | 118 [1] 118 💬 |
99 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D08570 D08570 💬 |
Terbutaline | 118 [1] 118 💬 |
100 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D02151 D02151 💬 |
Tulobuterol | 006 [1] 6 💬 |
101 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB3 [1] ADRB3 💬 |
D09535 D09535 💬 |
Mirabegron | 006 [4] 6 , 13, 53, 226 💬 |
102 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
103 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
104 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan | 058 [2] 58, 67 💬 |
105 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan cilexetil | 067 [1] 67 💬 |
106 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00626 D00626 💬 |
Candesartan cilexetil | 067 [1] 67 💬 |
107 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00523 D00523 💬 |
Irbesartan | 066 [4] 66, 167, 168, 222 💬 |
108 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
109 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
110 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00627 D00627 💬 |
Telmisartan | 066 [2] 66, 67 💬 |
111 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 |
112 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
AGTR1 [2] AGTR1, EDNRA 💬 |
D11776 D11776 💬 |
Sparsentan | 066 [3] 66, 218, 222 💬 |
113 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00297 D00297 💬 |
Digitoxin | 299 [1] 299 💬 |
114 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00298 D00298 💬 |
Digoxin | 008 [3] 8 , 46, 210 💬 |
115 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00615 D00615 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
116 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02914 D02914 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
117 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
118 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 [1] 67 💬 |
119 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
120 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
121 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
122 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00349 D00349 💬 |
Isradipine | 006 [1] 6 💬 |
123 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
124 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
125 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00437 D00437 💬 |
Nifedipine | 050 [2] 50, 81 💬 |
126 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01908 D01908 💬 |
Nilvadipine | 090 [1] 90 💬 |
127 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
128 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
129 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08441 D08441 💬 |
Propiverine | 226 [1] 226 💬 |
130 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 |
131 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
132 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
133 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
EDNRA [1] EDNRA 💬 |
D07077 D07077 💬 |
Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬 |
134 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
EDNRA [1] EDNRA 💬 |
D07171 D07171 💬 |
Sitaxentan | 086 [1] 86 💬 |
135 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
EDNRA [1] EDNRA 💬 |
D07741 D07741 💬 |
Zibotentan | 051 [1] 51 💬 |
136 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
EDNRA [2] EDNRA, EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 013 [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
137 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
EDNRA [2] EDNRA, EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 013 [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
138 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
EDNRA [2] EDNRA, EDNRB 💬 |
D10135 D10135 💬 |
Macitentan | 051 [5] 51, 85, 86, 88, 210 💬 |
139 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D00517 D00517 💬 |
Amyl Nitrite | 058 [1] 58 💬 |
140 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 [6] 51, 84, 86, 88, 225, 299 💬 |
141 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
INSR [1] INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 [1] 299 💬 |
142 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
INSR [1] INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 [1] 299 💬 |
143 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
INSR [1] INSR 💬 |
D00085 D00085 💬 |
Insulin human | 096 [2] 96, 156 💬 |
144 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
INSR [1] INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 [2] 96, 156 💬 |
145 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
146 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
147 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
148 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
149 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
MYH7 [1] MYH7 💬 |
D12265 D12265 💬 |
Mavacamten | 058 [1] 58 💬 |
150 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
NPR1 [1] NPR1 💬 |
D05147 D05147 💬 |
Nesiritide | 046 [2] 46, 58 💬 |
151 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
NPR1 [2] NPR1, NPR2 💬 |
D04051 D04051 💬 |
Erythrityl tetranitrate | 046 [1] 46 💬 |
152 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
NPR2 [1] NPR2 💬 |
D11190 D11190 💬 |
Vosoritide | 276 [1] 276 💬 |
153 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
OPRD1 [1] OPRD1 💬 |
D00729 D00729 💬 |
Loperamide | 013 [2] 13, 97 💬 |
154 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
OPRD1 [1] OPRD1 💬 |
D07113 D07113 💬 |
Loperamide | 013 [2] 13, 97 💬 |
155 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
OPRD1 [1] OPRD1 💬 |
D08144 D08144 💬 |
Loperamide | 013 [2] 13, 97 💬 |
156 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
OPRD1 [1] OPRD1 💬 |
D00843 D00843 💬 |
Nalbuphine | 085 [1] 85 💬 |
157 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
OPRD1 [1] OPRD1 💬 |
D08246 D08246 💬 |
Nalbuphine | 085 [1] 85 💬 |
158 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
OPRD1 [1] OPRD1 💬 |
D05111 D05111 💬 |
Nalmefene | 006 [1] 6 💬 |
159 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
OPRD1 [1] OPRD1 💬 |
D01340 D01340 💬 |
Naloxone | 006 [2] 6 , 226 💬 |
160 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
OPRD1 [1] OPRD1 💬 |
D08249 D08249 💬 |
Naloxone | 006 [2] 6 , 226 💬 |
161 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
OPRD1 [1] OPRD1 💬 |
D02095 D02095 💬 |
Naltrexone | 006 [13] 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
162 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
OPRD1 [1] OPRD1 💬 |
D05113 D05113 💬 |
Naltrexone | 006 [13] 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
163 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
OPRD1 [1] OPRD1 💬 |
D03783 D03783 💬 |
Oxycodone | 006 [7] 6 , 13, 46, 70, 226, 231, 298 💬 |
164 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
OPRD1 [1] OPRD1 💬 |
D05312 D05312 💬 |
Oxycodone | 006 [7] 6 , 13, 46, 70, 226, 231, 298 💬 |
165 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
OPRD1 [1] OPRD1 💬 |
D05462 D05462 💬 |
Oxycodone | 006 [7] 6 , 13, 46, 70, 226, 231, 298 💬 |
166 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PDE2A [3] PDE2A, PDE3A, PDE3B 💬 |
D07546 D07546 💬 |
Bucladesine | 246 [1] 246 💬 |
167 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PDE2A [3] PDE2A, PDE3A, PDE3B 💬 |
D00718 D00718 💬 |
Flavoxate | 226 [1] 226 💬 |
168 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PDE2A [3] PDE2A, PDE3A, PDE3B 💬 |
D07961 D07961 💬 |
Flavoxate | 226 [1] 226 💬 |
169 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PDE3A [2] PDE3A, PDE3B 💬 |
D01896 D01896 💬 |
Cilostazol | 051 [3] 51, 70, 124 💬 |
170 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PDE3A [2] PDE3A, PDE3B 💬 |
D01385 D01385 💬 |
Ibudilast | 002 [2] 2 , 13 💬 |
171 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PDE3A [2] PDE3A, PDE3B 💬 |
D04720 D04720 💬 |
Levosimendan | 002 [1] 2 💬 |
172 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PDE3A [2] PDE3A, PDE3B 💬 |
D00417 D00417 💬 |
Milrinone | 294 [1] 294 💬 |
173 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PDE3A [2] PDE3A, PDE3B 💬 |
D02085 D02085 💬 |
Milrinone | 294 [1] 294 💬 |
174 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PDE5A [1] PDE5A 💬 |
D00302 D00302 💬 |
Dipyridamole | 046 [6] 46, 49, 51, 66, 96, 224 💬 |
175 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PDE5A [1] PDE5A 💬 |
D02229 D02229 💬 |
Sildenafil | 006 [17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
176 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PDE5A [1] PDE5A 💬 |
D08514 D08514 💬 |
Sildenafil | 006 [17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
177 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PDE5A [1] PDE5A 💬 |
D02008 D02008 💬 |
Tadalafil | 006 [7] 6 , 51, 75, 84, 86, 113, 210 💬 |
178 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PDE5A [1] PDE5A 💬 |
D10027 D10027 💬 |
Udenafil | 086 [2] 86, 210 💬 |
179 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PDE5A [1] PDE5A 💬 |
D02731 D02731 💬 |
Vardenafil | 013 [3] 13, 86, 299 💬 |
180 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PDE5A [1] PDE5A 💬 |
D03260 D03260 💬 |
Vardenafil | 013 [3] 13, 86, 299 💬 |
181 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PDE5A [1] PDE5A 💬 |
D08668 D08668 💬 |
Vardenafil | 013 [3] 13, 86, 299 💬 |
182 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
183 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
184 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
185 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
186 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D09033 D09033 💬 |
Voclosporin | 222 [1] 222 💬 |
187 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PRKCE [1] PRKCE 💬 |
D09671 D09671 💬 |
Sotrastaurin | 097 [1] 97 💬 |
188 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
189 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
190 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ROCK1 [2] ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 [4] 2 , 5 , 7 , 51 💬 |
191 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ROCK2 [1] ROCK2 💬 |
D11815 D11815 💬 |
Belumosudil | 051 [1] 51 💬 |