Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Adipocytokine signaling pathway 💬
1件: TNF 💬 D02597 💬 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
2 Adipocytokine signaling pathway 💬
1件: TNF 💬 D03441 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
3 Adrenergic signaling in cardiomyocytes 💬
1件: ADRB1 💬 D00601 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
4 Adrenergic signaling in cardiomyocytes 💬
1件: ADRB1 💬 D02358 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
5 Adrenergic signaling in cardiomyocytes 💬
1件: ADRB1 💬 D05011 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
6 Adrenergic signaling in cardiomyocytes 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine 1件: 226 💬
7 Adrenergic signaling in cardiomyocytes 💬
1件: SCN5A 💬 D01450 💬 Bupivacaine 8件: 46, 51, 53, 70, 96, 168, 226, 298 💬
8 Adrenergic signaling in cardiomyocytes 💬
1件: SCN5A 💬 D07552 💬 Bupivacaine 8件: 46, 51, 53, 70, 96, 168, 226, 298 💬
9 Adrenergic signaling in cardiomyocytes 💬
1件: SCN5A 💬 D00358 💬 Lidocaine 13件:  6 , 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256 💬
10 Adrenergic signaling in cardiomyocytes 💬
1件: SCN5A 💬 D02086 💬 Lidocaine 13件:  6 , 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256 💬
11 Adrenergic signaling in cardiomyocytes 💬
1件: SCN5A 💬 D08127 💬 Lidocaine 13件:  6 , 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256 💬
12 African trypanosomiasis 💬
1件: TNF 💬 D02597 💬 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
13 African trypanosomiasis 💬
1件: TNF 💬 D03441 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
14 AGE-RAGE signaling pathway in diabetic complications 💬
1件: TNF 💬 D02597 💬 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
15 AGE-RAGE signaling pathway in diabetic complications 💬
1件: TNF 💬 D03441 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
16 Alcoholic liver disease 💬
1件: TNF 💬 D02597 💬 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
17 Alcoholic liver disease 💬
1件: TNF 💬 D03441 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
18 Aldosterone synthesis and secretion 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine 1件: 226 💬
19 Aldosterone synthesis and secretion 💬
1件: PDE2A 💬 D00718 💬 Flavoxate 1件: 226 💬
20 Aldosterone synthesis and secretion 💬
1件: PDE2A 💬 D07961 💬 Flavoxate 1件: 226 💬
21 Allograft rejection 💬
1件: TNF 💬 D02597 💬 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
22 Allograft rejection 💬
1件: TNF 💬 D03441 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
23 Alzheimer disease 💬
7件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM1, CHRM3, CHRM5 💬 D08441 💬 Propiverine 1件: 226 💬
24 Alzheimer disease 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
25 Alzheimer disease 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
26 Alzheimer disease 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
27 Alzheimer disease 💬
1件: PTGS2 💬 D00813 💬 Ketorolac 2件: 70, 226 💬
28 Alzheimer disease 💬
1件: PTGS2 💬 D08104 💬 Ketorolac 2件: 70, 226 💬
29 Alzheimer disease 💬
1件: TNF 💬 D02597 💬 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
30 Alzheimer disease 💬
1件: TNF 💬 D03441 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
31 Amoebiasis 💬
1件: TNF 💬 D02597 💬 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
32 Amoebiasis 💬
1件: TNF 💬 D03441 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
33 Amphetamine addiction 💬
2件: CACNA1C, CACNA1D 💬 D08441 💬 Propiverine 1件: 226 💬
34 Amphetamine addiction 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
35 Amphetamine addiction 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
36 Amphetamine addiction 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
37 Amyotrophic lateral sclerosis 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
38 Amyotrophic lateral sclerosis 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
39 Amyotrophic lateral sclerosis 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
40 Amyotrophic lateral sclerosis 💬
1件: TNF 💬 D02597 💬 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
41 Amyotrophic lateral sclerosis 💬
1件: TNF 💬 D03441 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
42 Antifolate resistance 💬
1件: TNF 💬 D02597 💬 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
43 Antifolate resistance 💬
1件: TNF 💬 D03441 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
44 Antigen processing and presentation 💬
1件: TNF 💬 D02597 💬 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
45 Antigen processing and presentation 💬
1件: TNF 💬 D03441 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
46 Apelin signaling pathway 💬
1件: PDE3B 💬 D00718 💬 Flavoxate 1件: 226 💬
47 Apelin signaling pathway 💬
1件: PDE3B 💬 D07961 💬 Flavoxate 1件: 226 💬
48 Apoptosis 💬
1件: NGF 💬 D09387 💬 Tanezumab 2件: 226, 298 💬
49 Apoptosis 💬
1件: TNF 💬 D02597 💬 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
50 Apoptosis 💬
1件: TNF 💬 D03441 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
51 Arachidonic acid metabolism 💬
2件: PTGS1, PTGS2 💬 D00813 💬 Ketorolac 2件: 70, 226 💬
52 Arachidonic acid metabolism 💬
2件: PTGS1, PTGS2 💬 D08104 💬 Ketorolac 2件: 70, 226 💬
53 Arrhythmogenic right ventricular cardiomyopathy 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine 1件: 226 💬
54 Asthma 💬
1件: FCER1A 💬 D05251 💬 Omalizumab 7件: 46, 53, 65, 98, 162, 226, 299 💬
55 Asthma 💬
1件: TNF 💬 D02597 💬 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
56 Asthma 💬
1件: TNF 💬 D03441 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
57 Axon guidance 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
58 Axon guidance 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
59 Axon guidance 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
60 B cell receptor signaling pathway 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
61 B cell receptor signaling pathway 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
62 B cell receptor signaling pathway 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
63 Breast cancer 💬
2件: ESR1, ESR2 💬 D00105 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
64 Breast cancer 💬
2件: ESR1, ESR2 💬 D01413 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
65 Breast cancer 💬
2件: ESR1, ESR2 💬 D01617 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
66 Breast cancer 💬
2件: ESR1, ESR2 💬 D01953 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
67 Breast cancer 💬
2件: ESR1, ESR2 💬 D04061 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
68 Breast cancer 💬
2件: ESR1, ESR2 💬 D04063 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
69 Breast cancer 💬
2件: ESR1, ESR2 💬 D04064 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
70 Breast cancer 💬
2件: ESR1, ESR2 💬 D04065 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
71 C-type lectin receptor signaling pathway 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
72 C-type lectin receptor signaling pathway 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
73 C-type lectin receptor signaling pathway 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
74 C-type lectin receptor signaling pathway 💬
1件: PTGS2 💬 D00813 💬 Ketorolac 2件: 70, 226 💬
75 C-type lectin receptor signaling pathway 💬
1件: PTGS2 💬 D08104 💬 Ketorolac 2件: 70, 226 💬
76 C-type lectin receptor signaling pathway 💬
1件: TNF 💬 D02597 💬 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
77 C-type lectin receptor signaling pathway 💬
1件: TNF 💬 D03441 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
78 Calcium signaling pathway 💬
1件: ADRB1 💬 D00601 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
79 Calcium signaling pathway 💬
1件: ADRB1 💬 D02358 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
80 Calcium signaling pathway 💬
1件: ADRB1 💬 D05011 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
81 Calcium signaling pathway 💬
1件: ADRB3 💬 D09535 💬 Mirabegron 4件:  6 , 13, 53, 226 💬
82 Calcium signaling pathway 💬
8件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM1, CHRM2, CHRM3, CHRM5 💬 D08441 💬 Propiverine 1件: 226 💬
83 Calcium signaling pathway 💬
1件: NGF 💬 D09387 💬 Tanezumab 2件: 226, 298 💬
84 Calcium signaling pathway 💬
1件: OXTR 💬 D00089 💬 Oxytocin 6件:  6 , 72, 127, 193, 206, 226 💬
85 Calcium signaling pathway 💬
1件: P2RX3 💬 D11349 💬 Gefapixant 2件: 85, 226 💬
86 Calcium signaling pathway 💬
3件: PDE1A, PDE1B, PDE1C 💬 D00718 💬 Flavoxate 1件: 226 💬
87 Calcium signaling pathway 💬
3件: PDE1A, PDE1B, PDE1C 💬 D07961 💬 Flavoxate 1件: 226 💬
88 Calcium signaling pathway 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
89 Calcium signaling pathway 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
90 Calcium signaling pathway 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
91 cAMP signaling pathway 💬
1件: ADRB1 💬 D00601 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
92 cAMP signaling pathway 💬
1件: ADRB1 💬 D02358 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
93 cAMP signaling pathway 💬
1件: ADRB1 💬 D05011 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
94 cAMP signaling pathway 💬
6件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM1, CHRM2 💬 D08441 💬 Propiverine 1件: 226 💬
95 cAMP signaling pathway 💬
1件: OXTR 💬 D00089 💬 Oxytocin 6件:  6 , 72, 127, 193, 206, 226 💬
96 cAMP signaling pathway 💬
7件: PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 D00718 💬 Flavoxate 1件: 226 💬
97 cAMP signaling pathway 💬
7件: PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 D07961 💬 Flavoxate 1件: 226 💬
98 Carbohydrate digestion and absorption 💬
1件: CACNA1D 💬 D08441 💬 Propiverine 1件: 226 💬
99 Cardiac muscle contraction 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine 1件: 226 💬
100 Cellular senescence 💬
1件: CACNA1D 💬 D08441 💬 Propiverine 1件: 226 💬
101 Cellular senescence 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
102 Cellular senescence 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
103 Cellular senescence 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
104 cGMP-PKG signaling pathway 💬
3件: ADRA2A, ADRA2B, ADRA2C 💬 D00514 💬 Dexmedetomidine 13件:  2 ,  4 ,  6 , 21, 34, 46, 70, 107, 113, 212, 215, 226, 280 💬
105 cGMP-PKG signaling pathway 💬
3件: ADRA2A, ADRA2B, ADRA2C 💬 D01205 💬 Dexmedetomidine 13件:  2 ,  4 ,  6 , 21, 34, 46, 70, 107, 113, 212, 215, 226, 280 💬
106 cGMP-PKG signaling pathway 💬
1件: ADRB1 💬 D00601 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
107 cGMP-PKG signaling pathway 💬
1件: ADRB1 💬 D02358 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
108 cGMP-PKG signaling pathway 💬
1件: ADRB1 💬 D05011 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
109 cGMP-PKG signaling pathway 💬
1件: ADRB3 💬 D09535 💬 Mirabegron 4件:  6 , 13, 53, 226 💬
110 cGMP-PKG signaling pathway 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine 1件: 226 💬
111 cGMP-PKG signaling pathway 💬
1件: OPRD1 💬 D01340 💬 Naloxone 2件:  6 , 226 💬
112 cGMP-PKG signaling pathway 💬
1件: OPRD1 💬 D08249 💬 Naloxone 2件:  6 , 226 💬
113 cGMP-PKG signaling pathway 💬
1件: OPRD1 💬 D02095 💬 Naltrexone 13件:  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
114 cGMP-PKG signaling pathway 💬
1件: OPRD1 💬 D05113 💬 Naltrexone 13件:  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
115 cGMP-PKG signaling pathway 💬
1件: OPRD1 💬 D03783 💬 Oxycodone 7件:  6 , 13, 46, 70, 226, 231, 298 💬
116 cGMP-PKG signaling pathway 💬
1件: OPRD1 💬 D05312 💬 Oxycodone 7件:  6 , 13, 46, 70, 226, 231, 298 💬
117 cGMP-PKG signaling pathway 💬
1件: OPRD1 💬 D05462 💬 Oxycodone 7件:  6 , 13, 46, 70, 226, 231, 298 💬
118 cGMP-PKG signaling pathway 💬
3件: PDE2A, PDE3A, PDE3B 💬 D00718 💬 Flavoxate 1件: 226 💬
119 cGMP-PKG signaling pathway 💬
3件: PDE2A, PDE3A, PDE3B 💬 D07961 💬 Flavoxate 1件: 226 💬
120 cGMP-PKG signaling pathway 💬
1件: PDE5A 💬 D02229 💬 Sildenafil 17件:  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
121 cGMP-PKG signaling pathway 💬
1件: PDE5A 💬 D08514 💬 Sildenafil 17件:  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
122 cGMP-PKG signaling pathway 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
123 cGMP-PKG signaling pathway 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
124 cGMP-PKG signaling pathway 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
125 Chagas disease 💬
1件: TNF 💬 D02597 💬 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
126 Chagas disease 💬
1件: TNF 💬 D03441 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
127 Chemical carcinogenesis - DNA adducts 💬
1件: PTGS2 💬 D00813 💬 Ketorolac 2件: 70, 226 💬
128 Chemical carcinogenesis - DNA adducts 💬
1件: PTGS2 💬 D08104 💬 Ketorolac 2件: 70, 226 💬
129 Chemical carcinogenesis - receptor activation 💬
1件: ADRB1 💬 D00601 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
130 Chemical carcinogenesis - receptor activation 💬
1件: ADRB1 💬 D02358 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
131 Chemical carcinogenesis - receptor activation 💬
1件: ADRB1 💬 D05011 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
132 Chemical carcinogenesis - receptor activation 💬
1件: ADRB3 💬 D09535 💬 Mirabegron 4件:  6 , 13, 53, 226 💬
133 Chemical carcinogenesis - receptor activation 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine 1件: 226 💬
134 Chemical carcinogenesis - receptor activation 💬
2件: ESR1, ESR2 💬 D00105 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
135 Chemical carcinogenesis - receptor activation 💬
2件: ESR1, ESR2 💬 D01413 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
136 Chemical carcinogenesis - receptor activation 💬
2件: ESR1, ESR2 💬 D01617 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
137 Chemical carcinogenesis - receptor activation 💬
2件: ESR1, ESR2 💬 D01953 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
138 Chemical carcinogenesis - receptor activation 💬
2件: ESR1, ESR2 💬 D04061 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
139 Chemical carcinogenesis - receptor activation 💬
2件: ESR1, ESR2 💬 D04063 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
140 Chemical carcinogenesis - receptor activation 💬
2件: ESR1, ESR2 💬 D04064 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
141 Chemical carcinogenesis - receptor activation 💬
2件: ESR1, ESR2 💬 D04065 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
142 Cholinergic synapse 💬
9件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D08441 💬 Propiverine 1件: 226 💬
143 Circadian entrainment 💬
2件: CACNA1C, CACNA1D 💬 D08441 💬 Propiverine 1件: 226 💬
144 Complement and coagulation cascades 💬
1件: SERPINC1 💬 D07510 💬 Heparin 12件: 47, 60, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317 💬
145 Coronavirus disease - COVID-19 💬
1件: TNF 💬 D02597 💬 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
146 Coronavirus disease - COVID-19 💬
1件: TNF 💬 D03441 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
147 Cortisol synthesis and secretion 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine 1件: 226 💬
148 Cortisol synthesis and secretion 💬
2件: PDE8A, PDE8B 💬 D00718 💬 Flavoxate 1件: 226 💬
149 Cortisol synthesis and secretion 💬
2件: PDE8A, PDE8B 💬 D07961 💬 Flavoxate 1件: 226 💬
150 Cushing syndrome 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine 1件: 226 💬
151 Cushing syndrome 💬
3件: PDE11A, PDE8A, PDE8B 💬 D00718 💬 Flavoxate 1件: 226 💬
152 Cushing syndrome 💬
3件: PDE11A, PDE8A, PDE8B 💬 D07961 💬 Flavoxate 1件: 226 💬
153 Cytokine-cytokine receptor interaction 💬
1件: NGF 💬 D09387 💬 Tanezumab 2件: 226, 298 💬
154 Cytokine-cytokine receptor interaction 💬
1件: TNF 💬 D02597 💬 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
155 Cytokine-cytokine receptor interaction 💬
1件: TNF 💬 D03441 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
156 Dilated cardiomyopathy 💬
1件: ADRB1 💬 D00601 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
157 Dilated cardiomyopathy 💬
1件: ADRB1 💬 D02358 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
158 Dilated cardiomyopathy 💬
1件: ADRB1 💬 D05011 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
159 Dilated cardiomyopathy 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine 1件: 226 💬
160 Dilated cardiomyopathy 💬
1件: TNF 💬 D02597 💬 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
161 Dilated cardiomyopathy 💬
1件: TNF 💬 D03441 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
162 Dopaminergic synapse 💬
2件: CACNA1C, CACNA1D 💬 D08441 💬 Propiverine 1件: 226 💬
163 Dopaminergic synapse 💬
3件: PPP3CA, PPP3CB, PPP3CC 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
164 Dopaminergic synapse 💬
3件: PPP3CA, PPP3CB, PPP3CC 💬 D00107 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
165 Dopaminergic synapse 💬
3件: PPP3CA, PPP3CB, PPP3CC 💬 D08556 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
166 Dopaminergic synapse 💬
1件: SCN1A 💬 D01450 💬 Bupivacaine 8件: 46, 51, 53, 70, 96, 168, 226, 298 💬
167 Dopaminergic synapse 💬
1件: SCN1A 💬 D07552 💬 Bupivacaine 8件: 46, 51, 53, 70, 96, 168, 226, 298 💬
168 Dopaminergic synapse 💬
1件: SCN1A 💬 D00358 💬 Lidocaine 13件:  6 , 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256 💬
169 Dopaminergic synapse 💬
1件: SCN1A 💬 D02086 💬 Lidocaine 13件:  6 , 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256 💬
170 Dopaminergic synapse 💬
1件: SCN1A 💬 D08127 💬 Lidocaine 13件:  6 , 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256 💬
171 Drug metabolism - other enzymes 💬
2件: IMPDH1, IMPDH2 💬 D00752 💬 Mycophenolate mofetil 34件:  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
172 Drug metabolism - other enzymes 💬
2件: IMPDH1, IMPDH2 💬 D05094 💬 Mycophenolate mofetil 34件:  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
173 Drug metabolism - other enzymes 💬
2件: IMPDH1, IMPDH2 💬 D05095 💬 Mycophenolate mofetil 34件:  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
174 Drug metabolism - other enzymes 💬
2件: IMPDH1, IMPDH2 💬 D05096 💬 Mycophenolic acid 36件:  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
175 Endocrine and other factor-regulated calcium reabsorption 💬
1件: ESR1 💬 D00105 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
176 Endocrine and other factor-regulated calcium reabsorption 💬
1件: ESR1 💬 D01413 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
177 Endocrine and other factor-regulated calcium reabsorption 💬
1件: ESR1 💬 D01617 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
178 Endocrine and other factor-regulated calcium reabsorption 💬
1件: ESR1 💬 D01953 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
179 Endocrine and other factor-regulated calcium reabsorption 💬
1件: ESR1 💬 D04061 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
180 Endocrine and other factor-regulated calcium reabsorption 💬
1件: ESR1 💬 D04063 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
181 Endocrine and other factor-regulated calcium reabsorption 💬
1件: ESR1 💬 D04064 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
182 Endocrine and other factor-regulated calcium reabsorption 💬
1件: ESR1 💬 D04065 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
183 Endocrine resistance 💬
2件: ESR1, ESR2 💬 D00105 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
184 Endocrine resistance 💬
2件: ESR1, ESR2 💬 D01413 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
185 Endocrine resistance 💬
2件: ESR1, ESR2 💬 D01617 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
186 Endocrine resistance 💬
2件: ESR1, ESR2 💬 D01953 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
187 Endocrine resistance 💬
2件: ESR1, ESR2 💬 D04061 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
188 Endocrine resistance 💬
2件: ESR1, ESR2 💬 D04063 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
189 Endocrine resistance 💬
2件: ESR1, ESR2 💬 D04064 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
190 Endocrine resistance 💬
2件: ESR1, ESR2 💬 D04065 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
191 Epstein-Barr virus infection 💬
1件: TNF 💬 D02597 💬 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
192 Epstein-Barr virus infection 💬
1件: TNF 💬 D03441 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
193 Estrogen signaling pathway 💬
2件: ESR1, ESR2 💬 D00105 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
194 Estrogen signaling pathway 💬
2件: ESR1, ESR2 💬 D01413 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
195 Estrogen signaling pathway 💬
2件: ESR1, ESR2 💬 D01617 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
196 Estrogen signaling pathway 💬
2件: ESR1, ESR2 💬 D01953 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
197 Estrogen signaling pathway 💬
2件: ESR1, ESR2 💬 D04061 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
198 Estrogen signaling pathway 💬
2件: ESR1, ESR2 💬 D04063 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
199 Estrogen signaling pathway 💬
2件: ESR1, ESR2 💬 D04064 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
200 Estrogen signaling pathway 💬
2件: ESR1, ESR2 💬 D04065 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
201 Estrogen signaling pathway 💬
1件: OPRM1 💬 D01340 💬 Naloxone 2件:  6 , 226 💬
202 Estrogen signaling pathway 💬
1件: OPRM1 💬 D08249 💬 Naloxone 2件:  6 , 226 💬
203 Estrogen signaling pathway 💬
1件: OPRM1 💬 D02095 💬 Naltrexone 13件:  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
204 Estrogen signaling pathway 💬
1件: OPRM1 💬 D05113 💬 Naltrexone 13件:  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
205 Estrogen signaling pathway 💬
1件: OPRM1 💬 D03783 💬 Oxycodone 7件:  6 , 13, 46, 70, 226, 231, 298 💬
206 Estrogen signaling pathway 💬
1件: OPRM1 💬 D05312 💬 Oxycodone 7件:  6 , 13, 46, 70, 226, 231, 298 💬
207 Estrogen signaling pathway 💬
1件: OPRM1 💬 D05462 💬 Oxycodone 7件:  6 , 13, 46, 70, 226, 231, 298 💬
208 Estrogen signaling pathway 💬
1件: OPRM1 💬 D01355 💬 Tramadol 5件: 46, 70, 78, 226, 271 💬
209 Estrogen signaling pathway 💬
1件: OPRM1 💬 D08623 💬 Tramadol 5件: 46, 70, 78, 226, 271 💬
210 Fc epsilon RI signaling pathway 💬
1件: FCER1A 💬 D05251 💬 Omalizumab 7件: 46, 53, 65, 98, 162, 226, 299 💬
211 Fc epsilon RI signaling pathway 💬
1件: TNF 💬 D02597 💬 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
212