Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Central carbon metabolism in cancer 💬
1件: EGFR 💬 D03455 💬 Cetuximab 5件: 34, 51, 86, 89, 331 💬
2 Central carbon metabolism in cancer 💬
1件: EGFR 💬 D04023 💬 Erlotinib 1件: 94 💬
3 Central carbon metabolism in cancer 💬
1件: EGFR 💬 D07907 💬 Erlotinib 1件: 94 💬
4 Central carbon metabolism in cancer 💬
1件: EGFR 💬 D01977 💬 Gefitinib 1件: 75 💬
5 Central carbon metabolism in cancer 💬
1件: EGFR 💬 D11251 💬 Icotinib 1件: 34 💬
6 Central carbon metabolism in cancer 💬
2件: EGFR, ERBB2 💬 D04024 💬 Lapatinib 3件: 34, 74, 75 💬
7 Central carbon metabolism in cancer 💬
2件: EGFR, ERBB2 💬 D08108 💬 Lapatinib 3件: 34, 74, 75 💬
8 Central carbon metabolism in cancer 💬
2件: EGFR, ERBB2 💬 D11772 💬 Tesevatinib 1件: 67 💬
9 Central carbon metabolism in cancer 💬
3件: FGFR1, FGFR2, FGFR3 💬 D11589 💬 Infigratinib 1件: 276 💬
10 Central carbon metabolism in cancer 💬
5件: FGFR1, FGFR2, FGFR3, PDGFRA, PDGFRB 💬 D10481 💬 Nintedanib 5件: 51, 85, 89, 227, 228 💬
11 Central carbon metabolism in cancer 💬
1件: FGFR2 💬 D05338 💬 Palifermin 5件: 13, 36, 38, 39, 65 💬
12 Central carbon metabolism in cancer 💬
2件: FLT3, KIT 💬 D11270 💬 Pexidartinib 1件: 34 💬
13 Central carbon metabolism in cancer 💬
5件: FLT3, KIT, PDGFRA, PDGFRB, RET 💬 D06402 💬 Sunitinib 2件: 28, 34 💬
14 Central carbon metabolism in cancer 💬
5件: FLT3, KIT, PDGFRA, PDGFRB, RET 💬 D08552 💬 Sunitinib 2件: 28, 34 💬
15 Central carbon metabolism in cancer 💬
5件: FLT3, KIT, PDGFRB, RAF1, RET 💬 D06272 💬 Sorafenib 2件: 34, 86 💬
16 Central carbon metabolism in cancer 💬
5件: FLT3, KIT, PDGFRB, RAF1, RET 💬 D08524 💬 Sorafenib 2件: 34, 86 💬
17 Central carbon metabolism in cancer 💬
1件: KIT 💬 D10229 💬 Masitinib 6件:  2 ,  5 ,  6 , 13, 46, 96 💬
18 Central carbon metabolism in cancer 💬
2件: KIT, PDGFRA 💬 D01441 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
19 Central carbon metabolism in cancer 💬
2件: KIT, PDGFRA 💬 D08066 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
20 Central carbon metabolism in cancer 💬
3件: KIT, PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬
21 Central carbon metabolism in cancer 💬
2件: KIT, PDGFRB 💬 D03658 💬 Dasatinib 2件: 51, 85 💬
22 Central carbon metabolism in cancer 💬
2件: KIT, PDGFRB 💬 D06414 💬 Dasatinib 2件: 51, 85 💬
23 Central carbon metabolism in cancer 💬
2件: MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib 1件: 34 💬
24 Central carbon metabolism in cancer 💬
2件: MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib 1件: 280 💬
25 Central carbon metabolism in cancer 💬
2件: MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib 1件: 34 💬
26 Central carbon metabolism in cancer 💬
2件: MAP2K1, MAP2K2 💬 D10175 💬 Trametinib 4件:  2 , 34, 279, 280 💬
27 Central carbon metabolism in cancer 💬
1件: MET 💬 D10062 💬 Cabozantinib 1件: 34 💬
28 Central carbon metabolism in cancer 💬
1件: MTOR 💬 D02714 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
29 Central carbon metabolism in cancer 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
30 Central carbon metabolism in cancer 💬
1件: MTOR 💬 D06068 💬 Temsirolimus 4件: 13, 34, 89, 331 💬
31 Central carbon metabolism in cancer 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
32 Central carbon metabolism in cancer 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬