Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Diabetic cardiomyopathy 💬
1件: ACE 💬 D00620 💬 Benazepril 4件: 49, 57, 218, 224 💬
2 Diabetic cardiomyopathy 💬
1件: ACE 💬 D07499 💬 Benazepril 4件: 49, 57, 218, 224 💬
3 Diabetic cardiomyopathy 💬
1件: ACE 💬 D00251 💬 Captopril 8件:  6 , 17, 46, 86, 96, 97, 107, 271 💬
4 Diabetic cardiomyopathy 💬
1件: ACE 💬 D01069 💬 Cilazapril 1件: 66 💬
5 Diabetic cardiomyopathy 💬
1件: ACE 💬 D07699 💬 Cilazapril 1件: 66 💬
6 Diabetic cardiomyopathy 💬
1件: ACE 💬 D00621 💬 Enalapril 6件: 19, 46, 66, 113, 210, 222 💬
7 Diabetic cardiomyopathy 💬
1件: ACE 💬 D07892 💬 Enalapril 6件: 19, 46, 66, 113, 210, 222 💬
8 Diabetic cardiomyopathy 💬
1件: ACE 💬 D08068 💬 Imidapril 1件: 67 💬
9 Diabetic cardiomyopathy 💬
1件: ACE 💬 D00362 💬 Lisinopril 7件: 19, 46, 49, 66, 67, 113, 222 💬
10 Diabetic cardiomyopathy 💬
1件: ACE 💬 D08131 💬 Lisinopril 7件: 19, 46, 49, 66, 67, 113, 222 💬
11 Diabetic cardiomyopathy 💬
1件: ACE 💬 D00623 💬 Moexipril 1件: 93 💬
12 Diabetic cardiomyopathy 💬
1件: ACE 💬 D08225 💬 Moexipril 1件: 93 💬
13 Diabetic cardiomyopathy 💬
1件: ACE 💬 D00624 💬 Perindopril 4件: 58, 113, 167, 222 💬
14 Diabetic cardiomyopathy 💬
1件: ACE 💬 D03753 💬 Perindopril 4件: 58, 113, 167, 222 💬
15 Diabetic cardiomyopathy 💬
1件: ACE 💬 D00459 💬 Quinapril 1件: 19 💬
16 Diabetic cardiomyopathy 💬
1件: ACE 💬 D03752 💬 Quinapril 1件: 19 💬
17 Diabetic cardiomyopathy 💬
1件: ACE 💬 D00421 💬 Ramipril 7件: 46, 49, 66, 67, 113, 218, 257 💬
18 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 D00150 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬
19 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 D02014 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬
20 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 D00522 💬 Candesartan 2件: 58, 67 💬
21 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 D00522 💬 Candesartan cilexetil 1件: 67 💬
22 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 D00626 💬 Candesartan cilexetil 1件: 67 💬
23 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 D00523 💬 Irbesartan 4件: 66, 167, 168, 222 💬
24 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 D00357 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
25 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 D08146 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
26 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 D11776 💬 Sparsentan 3件: 66, 218, 222 💬
27 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 D00627 💬 Telmisartan 2件: 66, 67 💬
28 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 D00400 💬 Valsartan 7件: 57, 58, 66, 75, 218, 222, 224 💬
29 Diabetic cardiomyopathy 💬
2件: CPT1B, CPT2 💬 D05442 💬 Perhexiline 2件: 58, 272 💬
30 Diabetic cardiomyopathy 💬
2件: CPT1B, CPT2 💬 D08340 💬 Perhexiline 2件: 58, 272 💬
31 Diabetic cardiomyopathy 💬
1件: INSR 💬 D04539 💬 Insulin detemir 1件: 299 💬
32 Diabetic cardiomyopathy 💬
1件: INSR 💬 D03250 💬 Insulin glargine 1件: 299 💬
33 Diabetic cardiomyopathy 💬
1件: INSR 💬 D00085 💬 Insulin human 2件: 96, 156 💬
34 Diabetic cardiomyopathy 💬
1件: INSR 💬 D03230 💬 Insulin human 2件: 96, 156 💬
35 Diabetic cardiomyopathy 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod 2件: 113, 222 💬
36 Diabetic cardiomyopathy 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod 1件:  8  💬
37 Diabetic cardiomyopathy 💬
1件: MTOR 💬 D02714 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
38 Diabetic cardiomyopathy 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
39 Diabetic cardiomyopathy 💬
1件: MTOR 💬 D06068 💬 Temsirolimus 4件: 13, 34, 89, 331 💬
40 Diabetic cardiomyopathy 💬
1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
41 Diabetic cardiomyopathy 💬
1件: PARP1 💬 D09730 💬 Olaparib 2件: 86, 285 💬
42 Diabetic cardiomyopathy 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
43 Diabetic cardiomyopathy 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
44 Diabetic cardiomyopathy 💬
1件: PPARA 💬 D01366 💬 Bezafibrate 7件: 20, 93, 94, 160, 296, 316, 324 💬
45 Diabetic cardiomyopathy 💬
1件: PPARA 💬 D11208 💬 Elafibranor 1件: 93 💬
46 Diabetic cardiomyopathy 💬
1件: PPARA 💬 D00565 💬 Fenofibrate 5件:  8 , 79, 93, 94, 265 💬
47 Diabetic cardiomyopathy 💬
1件: PPARA 💬 D10711 💬 Pemafibrate 1件: 93 💬
48 Diabetic cardiomyopathy 💬
1件: PRKCD 💬 D09671 💬 Sotrastaurin 1件: 97 💬
49 Diabetic cardiomyopathy 💬
1件: RELA 💬 D12181 💬 Edasalonexent 1件: 113 💬
50 Diabetic cardiomyopathy 💬
1件: REN 💬 D03208 💬 Aliskiren 3件: 66, 167, 222 💬
51 Diabetic cardiomyopathy 💬
3件: TGFB1, TGFB2, TGFB3 💬 D09620 💬 Fresolimumab 4件: 51, 85, 222, 274 💬