Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Epstein-Barr virus infection 💬
1件: BCL2 💬 D10679 💬 Venetoclax 1件: 28 💬
2 Epstein-Barr virus infection 💬
1件: BTK 💬 D10893 💬 Acalabrutinib 2件: 46, 61 💬
3 Epstein-Barr virus infection 💬
1件: BTK 💬 D11478 💬 Branebrutinib 3件: 46, 49, 53 💬
4 Epstein-Barr virus infection 💬
1件: BTK 💬 D11457 💬 Fenebrutinib 1件: 13 💬
5 Epstein-Barr virus infection 💬
1件: BTK 💬 D10223 💬 Ibrutinib 3件: 28, 60, 61 💬
6 Epstein-Barr virus infection 💬
1件: BTK 💬 D12160 💬 Orelabrutinib 3件: 13, 61, 63 💬
7 Epstein-Barr virus infection 💬
1件: BTK 💬 D11422 💬 Zanubrutinib 2件: 300, 331 💬
8 Epstein-Barr virus infection 💬
1件: CASP9 💬 D11195 💬 Rimiducid 6件: 19, 60, 65, 284, 285, 326 💬
9 Epstein-Barr virus infection 💬
1件: CD19 💬 D11757 💬 Inebilizumab 4件: 11, 13, 51, 300 💬
10 Epstein-Barr virus infection 💬
3件: CD3D, CD3E, CD3G 💬 D05092 💬 Muromonab 3件: 60, 96, 97 💬
11 Epstein-Barr virus infection 💬
3件: CD3D, CD3E, CD3G 💬 D08959 💬 Otelixizumab 1件: 46 💬
12 Epstein-Barr virus infection 💬
3件: CD3D, CD3E, CD3G 💬 D06314 💬 Visilizumab 2件: 96, 97 💬
13 Epstein-Barr virus infection 💬
1件: CD3E 💬 D11463 💬 Mosunetuzumab 1件: 49 💬
14 Epstein-Barr virus infection 💬
1件: CD40 💬 D11357 💬 Bleselumab 1件: 222 💬
15 Epstein-Barr virus infection 💬
1件: CD40 💬 D11610 💬 Iscalimab 2件: 49, 53 💬
16 Epstein-Barr virus infection 💬
1件: CD40 💬 D11597 💬 Ravagalimab 2件: 53, 97 💬
17 Epstein-Barr virus infection 💬
1件: CD58 💬 D02800 💬 Alefacept 6件: 37, 60, 65, 164, 284, 285 💬
18 Epstein-Barr virus infection 💬
2件: CDK4, CDK6 💬 D10688 💬 Abemaciclib 1件: 34 💬
19 Epstein-Barr virus infection 💬
2件: HDAC1, HDAC2 💬 D06320 💬 Vorinostat 3件: 19, 75, 96 💬
20 Epstein-Barr virus infection 💬
20件: HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G 💬 D04318 💬 Glatiramer 4件:  2 , 13, 96, 156 💬
21 Epstein-Barr virus infection 💬
13件: IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 D09662 💬 Rontalizumab 1件: 49 💬
22 Epstein-Barr virus infection 💬
13件: IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 D09668 💬 Sifalimumab 1件: 49 💬
23 Epstein-Barr virus infection 💬
2件: IFNAR1, IFNAR2 💬 D11082 💬 Anifrolumab 2件: 46, 49 💬
24 Epstein-Barr virus infection 💬
2件: IFNAR1, IFNAR2 💬 D03305 💬 Interferon alfa 6件: 13, 25, 26, 28, 56, 96 💬
25 Epstein-Barr virus infection 💬
2件: IFNAR1, IFNAR2 💬 D00745 💬 Interferon alfa-2a 1件: 56 💬
26 Epstein-Barr virus infection 💬
2件: IFNAR1, IFNAR2 💬 D02745 💬 Interferon alfa-2b 2件: 25, 34 💬
27 Epstein-Barr virus infection 💬
2件: IFNAR1, IFNAR2 💬 D04554 💬 Interferon beta-1a 4件: 13, 26, 96, 97 💬
28 Epstein-Barr virus infection 💬
2件: IFNAR1, IFNAR2 💬 D00746 💬 Interferon beta-1b 1件: 13 💬
29 Epstein-Barr virus infection 💬
2件: IFNAR1, IFNAR2 💬 D10483 💬 Peginterferon beta-1a 1件: 13 💬
30 Epstein-Barr virus infection 💬
1件: IL6 💬 D09669 💬 Siltuximab 2件: 28, 331 💬
31 Epstein-Barr virus infection 💬
1件: IL6 💬 D10080 💬 Sirukumab 2件: 41, 46 💬
32 Epstein-Barr virus infection 💬
2件: IL6, TNF 💬 D01583 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
33 Epstein-Barr virus infection 💬
2件: IL6, TNF 💬 D08976 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
34 Epstein-Barr virus infection 💬
1件: ITGAL 💬 D03959 💬 Efalizumab 9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
35 Epstein-Barr virus infection 💬
1件: JAK1 💬 D10308 💬 Baricitinib 13件: 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
36 Epstein-Barr virus infection 💬
1件: JAK1 💬 D10871 💬 Filgotinib 6件: 46, 53, 96, 97, 222, 271 💬
37 Epstein-Barr virus infection 💬
1件: JAK1 💬 D10944 💬 Itacitinib 5件: 46, 51, 60, 97, 228 💬
38 Epstein-Barr virus infection 💬
1件: JAK1 💬 D09959 💬 Ruxolitinib 1件: 228 💬
39 Epstein-Barr virus infection 💬
1件: JAK1 💬 D10994 💬 Upadacitinib 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
40 Epstein-Barr virus infection 💬
2件: JAK1, JAK3 💬 D10653 💬 Peficitinib 1件: 46 💬
41 Epstein-Barr virus infection 💬
3件: JAK1, JAK3, TYK2 💬 D09970 💬 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
42 Epstein-Barr virus infection 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod 2件: 113, 222 💬
43 Epstein-Barr virus infection 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod 1件:  8  💬
44 Epstein-Barr virus infection 💬
1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
45 Epstein-Barr virus infection 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
46 Epstein-Barr virus infection 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
47 Epstein-Barr virus infection 💬
1件: RELA 💬 D12181 💬 Edasalonexent 1件: 113 💬
48 Epstein-Barr virus infection 💬
1件: SYK 💬 D09347 💬 Fostamatinib 4件: 46, 49, 61, 66 💬
49 Epstein-Barr virus infection 💬
1件: TNF 💬 D02597 💬 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
50 Epstein-Barr virus infection 💬
1件: TNF 💬 D03441 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
51 Epstein-Barr virus infection 💬
1件: TNF 💬 D00742 💬 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
52 Epstein-Barr virus infection 💬
1件: TNF 💬 D04358 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
53 Epstein-Barr virus infection 💬
1件: TNF 💬 D02598 💬 Infliximab 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
54 Epstein-Barr virus infection 💬
1件: TNF 💬 D04687 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
55 Epstein-Barr virus infection 💬
1件: TNF 💬 D09944 💬 Ozoralizumab 1件: 46 💬
56 Epstein-Barr virus infection 💬
1件: TNF 💬 D05393 💬 Pegsunercept 1件: 46 💬
57 Epstein-Barr virus infection 💬
1件: TNF 💬 D00754 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
58 Epstein-Barr virus infection 💬
1件: TYK2 💬 D11817 💬 Deucravacitinib 2件: 96, 97 💬