Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 ErbB signaling pathway 💬
1件: ABL1 💬 D01441 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
2 ErbB signaling pathway 💬
1件: ABL1 💬 D08066 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
3 ErbB signaling pathway 💬
1件: ABL1 💬 D08953 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬
4 ErbB signaling pathway 💬
2件: ABL1, SRC 💬 D03252 💬 Bosutinib 2件:  2 , 67 💬
5 ErbB signaling pathway 💬
2件: ABL1, SRC 💬 D03658 💬 Dasatinib 2件: 51, 85 💬
6 ErbB signaling pathway 💬
2件: ABL1, SRC 💬 D06414 💬 Dasatinib 2件: 51, 85 💬
7 ErbB signaling pathway 💬
2件: ABL1, SRC 💬 D09664 💬 Saracatinib 3件:  6 , 89, 272 💬
8 ErbB signaling pathway 💬
1件: BRAF 💬 D10064 💬 Dabrafenib 1件: 34 💬
9 ErbB signaling pathway 💬
2件: BRAF, RAF1 💬 D06272 💬 Sorafenib 2件: 34, 86 💬
10 ErbB signaling pathway 💬
2件: BRAF, RAF1 💬 D08524 💬 Sorafenib 2件: 34, 86 💬
11 ErbB signaling pathway 💬
1件: EGFR 💬 D03455 💬 Cetuximab 5件: 34, 51, 86, 89, 331 💬
12 ErbB signaling pathway 💬
1件: EGFR 💬 D04023 💬 Erlotinib 1件: 94 💬
13 ErbB signaling pathway 💬
1件: EGFR 💬 D07907 💬 Erlotinib 1件: 94 💬
14 ErbB signaling pathway 💬
1件: EGFR 💬 D01977 💬 Gefitinib 1件: 75 💬
15 ErbB signaling pathway 💬
1件: EGFR 💬 D11251 💬 Icotinib 1件: 34 💬
16 ErbB signaling pathway 💬
2件: EGFR, ERBB2 💬 D04024 💬 Lapatinib 3件: 34, 74, 75 💬
17 ErbB signaling pathway 💬
2件: EGFR, ERBB2 💬 D08108 💬 Lapatinib 3件: 34, 74, 75 💬
18 ErbB signaling pathway 💬
2件: EGFR, ERBB2 💬 D11772 💬 Tesevatinib 1件: 67 💬
19 ErbB signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib 1件: 34 💬
20 ErbB signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib 1件: 280 💬
21 ErbB signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib 1件: 34 💬
22 ErbB signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 D10175 💬 Trametinib 4件:  2 , 34, 279, 280 💬
23 ErbB signaling pathway 💬
1件: MTOR 💬 D02714 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
24 ErbB signaling pathway 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
25 ErbB signaling pathway 💬
1件: MTOR 💬 D06068 💬 Temsirolimus 4件: 13, 34, 89, 331 💬
26 ErbB signaling pathway 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
27 ErbB signaling pathway 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬