Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Hepatocellular carcinoma 💬
1件: BRAF 💬 D10064 💬 Dabrafenib 1件: 34 💬
2 Hepatocellular carcinoma 💬
2件: BRAF, RAF1 💬 D06272 💬 Sorafenib 2件: 34, 86 💬
3 Hepatocellular carcinoma 💬
2件: BRAF, RAF1 💬 D08524 💬 Sorafenib 2件: 34, 86 💬
4 Hepatocellular carcinoma 💬
2件: CDK4, CDK6 💬 D10688 💬 Abemaciclib 1件: 34 💬
5 Hepatocellular carcinoma 💬
1件: EGFR 💬 D03455 💬 Cetuximab 5件: 34, 51, 86, 89, 331 💬
6 Hepatocellular carcinoma 💬
1件: EGFR 💬 D04023 💬 Erlotinib 1件: 94 💬
7 Hepatocellular carcinoma 💬
1件: EGFR 💬 D07907 💬 Erlotinib 1件: 94 💬
8 Hepatocellular carcinoma 💬
1件: EGFR 💬 D01977 💬 Gefitinib 1件: 75 💬
9 Hepatocellular carcinoma 💬
1件: EGFR 💬 D11251 💬 Icotinib 1件: 34 💬
10 Hepatocellular carcinoma 💬
1件: EGFR 💬 D04024 💬 Lapatinib 3件: 34, 74, 75 💬
11 Hepatocellular carcinoma 💬
1件: EGFR 💬 D08108 💬 Lapatinib 3件: 34, 74, 75 💬
12 Hepatocellular carcinoma 💬
1件: EGFR 💬 D11772 💬 Tesevatinib 1件: 67 💬
13 Hepatocellular carcinoma 💬
1件: HMOX1 💬 D05922 💬 Stannsoporfin 1件: 254 💬
14 Hepatocellular carcinoma 💬
1件: IGF1R 💬 D09925 💬 Linsitinib 1件: 232 💬
15 Hepatocellular carcinoma 💬
1件: IGF1R 💬 D03297 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
16 Hepatocellular carcinoma 💬
1件: IGF1R 💬 D04870 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
17 Hepatocellular carcinoma 💬
1件: IGF1R 💬 D09680 💬 Teprotumumab 1件: 51 💬
18 Hepatocellular carcinoma 💬
1件: KEAP1 💬 D03846 💬 Dimethyl fumarate 5件: 13, 49, 51, 86, 296 💬
19 Hepatocellular carcinoma 💬
2件: MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib 1件: 34 💬
20 Hepatocellular carcinoma 💬
2件: MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib 1件: 280 💬
21 Hepatocellular carcinoma 💬
2件: MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib 1件: 34 💬
22 Hepatocellular carcinoma 💬
2件: MAP2K1, MAP2K2 💬 D10175 💬 Trametinib 4件:  2 , 34, 279, 280 💬
23 Hepatocellular carcinoma 💬
1件: MET 💬 D10062 💬 Cabozantinib 1件: 34 💬
24 Hepatocellular carcinoma 💬
1件: MTOR 💬 D02714 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
25 Hepatocellular carcinoma 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
26 Hepatocellular carcinoma 💬
1件: MTOR 💬 D06068 💬 Temsirolimus 4件: 13, 34, 89, 331 💬
27 Hepatocellular carcinoma 💬
1件: NFE2L2 💬 D10964 💬 Omaveloxolone 1件: 18 💬
28 Hepatocellular carcinoma 💬
1件: NQO1 💬 D00564 💬 Warfarin 13件:  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
29 Hepatocellular carcinoma 💬
1件: NQO1 💬 D01280 💬 Warfarin 13件:  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
30 Hepatocellular carcinoma 💬
1件: NQO1 💬 D08682 💬 Warfarin 13件:  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
31 Hepatocellular carcinoma 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
32 Hepatocellular carcinoma 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
33 Hepatocellular carcinoma 💬
3件: TGFB1, TGFB2, TGFB3 💬 D09620 💬 Fresolimumab 4件: 51, 85, 222, 274 💬