Target Gene/Pathway PATHWAY / GENE


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No. KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG DRUG DrugBank 指定難病告示番号
1 IGF1R 29件: EGFR tyrosine kinase inhibitor resistance 💬, Endocrine resistance 💬, MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, HIF-1 signaling pathway 💬, FoxO signaling pathway 💬, Oocyte meiosis 💬, Autophagy - animal 💬, Endocytosis 💬, mTOR signaling pathway 💬, PI3K-Akt signaling pathway 💬, AMPK signaling pathway 💬, Longevity regulating pathway 💬, Longevity regulating pathway - multiple species 💬, Focal adhesion 💬, Adherens junction 💬, Signaling pathways regulating pluripotency of stem cells 💬, Long-term depression 💬, Ovarian steroidogenesis 💬, Progesterone-mediated oocyte maturation 💬, Pathways in cancer 💬, Transcriptional misregulation in cancer 💬, Proteoglycans in cancer 💬, Glioma 💬, Prostate cancer 💬, Melanoma 💬, Breast cancer 💬, Hepatocellular carcinoma 💬 D03297 Mecasermin 6件: 65, 78, 96, 168, 265, 299
2 IGF1R 29件: EGFR tyrosine kinase inhibitor resistance 💬, Endocrine resistance 💬, MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, HIF-1 signaling pathway 💬, FoxO signaling pathway 💬, Oocyte meiosis 💬, Autophagy - animal 💬, Endocytosis 💬, mTOR signaling pathway 💬, PI3K-Akt signaling pathway 💬, AMPK signaling pathway 💬, Longevity regulating pathway 💬, Longevity regulating pathway - multiple species 💬, Focal adhesion 💬, Adherens junction 💬, Signaling pathways regulating pluripotency of stem cells 💬, Long-term depression 💬, Ovarian steroidogenesis 💬, Progesterone-mediated oocyte maturation 💬, Pathways in cancer 💬, Transcriptional misregulation in cancer 💬, Proteoglycans in cancer 💬, Glioma 💬, Prostate cancer 💬, Melanoma 💬, Breast cancer 💬, Hepatocellular carcinoma 💬 D04870 Mecasermin 6件: 65, 78, 96, 168, 265, 299
3 IGF1R 29件: EGFR tyrosine kinase inhibitor resistance 💬, Endocrine resistance 💬, MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, HIF-1 signaling pathway 💬, FoxO signaling pathway 💬, Oocyte meiosis 💬, Autophagy - animal 💬, Endocytosis 💬, mTOR signaling pathway 💬, PI3K-Akt signaling pathway 💬, AMPK signaling pathway 💬, Longevity regulating pathway 💬, Longevity regulating pathway - multiple species 💬, Focal adhesion 💬, Adherens junction 💬, Signaling pathways regulating pluripotency of stem cells 💬, Long-term depression 💬, Ovarian steroidogenesis 💬, Progesterone-mediated oocyte maturation 💬, Pathways in cancer 💬, Transcriptional misregulation in cancer 💬, Proteoglycans in cancer 💬, Glioma 💬, Prostate cancer 💬, Melanoma 💬, Breast cancer 💬, Hepatocellular carcinoma 💬 D09680 Teprotumumab 1件: 51
4 IGF1R 29件: EGFR tyrosine kinase inhibitor resistance 💬, Endocrine resistance 💬, MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, HIF-1 signaling pathway 💬, FoxO signaling pathway 💬, Oocyte meiosis 💬, Autophagy - animal 💬, Endocytosis 💬, mTOR signaling pathway 💬, PI3K-Akt signaling pathway 💬, AMPK signaling pathway 💬, Longevity regulating pathway 💬, Longevity regulating pathway - multiple species 💬, Focal adhesion 💬, Adherens junction 💬, Signaling pathways regulating pluripotency of stem cells 💬, Long-term depression 💬, Ovarian steroidogenesis 💬, Progesterone-mediated oocyte maturation 💬, Pathways in cancer 💬, Transcriptional misregulation in cancer 💬, Proteoglycans in cancer 💬, Glioma 💬, Prostate cancer 💬, Melanoma 💬, Breast cancer 💬, Hepatocellular carcinoma 💬 D09925 Linsitinib 1件: 232