Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Influenza A 💬
1件: CASP9 💬 D11195 💬 Rimiducid 6件: 19, 60, 65, 284, 285, 326 💬
2 Influenza A 💬
5件: CCL2, IL1A, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
3 Influenza A 💬
2件: CDK4, CDK6 💬 D10688 💬 Abemaciclib 1件: 34 💬
4 Influenza A 💬
1件: FDPS 💬 D00939 💬 Alendronic acid 7件: 19, 41, 46, 50, 271, 274, 299 💬
5 Influenza A 💬
1件: FDPS 💬 D07119 💬 Alendronic acid 7件: 19, 41, 46, 50, 271, 274, 299 💬
6 Influenza A 💬
1件: FDPS 💬 D08056 💬 Ibandronate 3件: 46, 49, 274 💬
7 Influenza A 💬
1件: FDPS 💬 D00941 💬 Pamidronic acid 3件: 270, 271, 274 💬
8 Influenza A 💬
1件: FDPS 💬 D07281 💬 Pamidronic acid 3件: 270, 271, 274 💬
9 Influenza A 💬
1件: FDPS 💬 D00942 💬 Risedronic acid 9件: 46, 50, 66, 93, 95, 96, 107, 113, 274 💬
10 Influenza A 💬
1件: FDPS 💬 D03234 💬 Risedronic acid 9件: 46, 50, 66, 93, 95, 96, 107, 113, 274 💬
11 Influenza A 💬
1件: FDPS 💬 D08484 💬 Risedronic acid 9件: 46, 50, 66, 93, 95, 96, 107, 113, 274 💬
12 Influenza A 💬
1件: FDPS 💬 D01968 💬 Zoledronic acid 13件:  5 ,  6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
13 Influenza A 💬
1件: FDPS 💬 D06378 💬 Zoledronic acid 13件:  5 ,  6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
14 Influenza A 💬
1件: FDPS 💬 D06379 💬 Zoledronic acid 13件:  5 ,  6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
15 Influenza A 💬
1件: FDPS 💬 D08689 💬 Zoledronic acid 13件:  5 ,  6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
16 Influenza A 💬
14件: HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 D04318 💬 Glatiramer 4件:  2 , 13, 96, 156 💬
17 Influenza A 💬
13件: IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 D09662 💬 Rontalizumab 1件: 49 💬
18 Influenza A 💬
13件: IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 D09668 💬 Sifalimumab 1件: 49 💬
19 Influenza A 💬
2件: IFNAR1, IFNAR2 💬 D11082 💬 Anifrolumab 2件: 46, 49 💬
20 Influenza A 💬
2件: IFNAR1, IFNAR2 💬 D03305 💬 Interferon alfa 6件: 13, 25, 26, 28, 56, 96 💬
21 Influenza A 💬
2件: IFNAR1, IFNAR2 💬 D00745 💬 Interferon alfa-2a 1件: 56 💬
22 Influenza A 💬
2件: IFNAR1, IFNAR2 💬 D02745 💬 Interferon alfa-2b 2件: 25, 34 💬
23 Influenza A 💬
2件: IFNAR1, IFNAR2 💬 D04554 💬 Interferon beta-1a 4件: 13, 26, 96, 97 💬
24 Influenza A 💬
2件: IFNAR1, IFNAR2 💬 D00746 💬 Interferon beta-1b 1件: 13 💬
25 Influenza A 💬
2件: IFNAR1, IFNAR2 💬 D10483 💬 Peginterferon beta-1a 1件: 13 💬
26 Influenza A 💬
1件: IFNG 💬 D11120 💬 Emapalumab 2件: 49, 107 💬
27 Influenza A 💬
1件: IFNG 💬 D04242 💬 Fontolizumab 1件: 46 💬
28 Influenza A 💬
2件: IFNGR1, IFNGR2 💬 D00747 💬 Interferon gamma-1b 7件: 18, 65, 85, 228, 299, 301, 326 💬
29 Influenza A 💬
2件: IL12A, IL12B 💬 D09214 💬 Ustekinumab 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
30 Influenza A 💬
1件: IL1A 💬 D11253 💬 Bermekimab 1件: 51 💬
31 Influenza A 💬
2件: IL1A, IL1B 💬 D06635 💬 Rilonacept 4件: 51, 106, 107, 266 💬
32 Influenza A 💬
1件: IL1B 💬 D09315 💬 Canakinumab 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
33 Influenza A 💬
1件: IL1B 💬 D09911 💬 Gevokizumab 4件: 41, 50, 56, 269 💬
34 Influenza A 💬
1件: IL6 💬 D09669 💬 Siltuximab 2件: 28, 331 💬
35 Influenza A 💬
1件: IL6 💬 D10080 💬 Sirukumab 2件: 41, 46 💬
36 Influenza A 💬
2件: IL6, TNF 💬 D08976 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
37 Influenza A 💬
1件: JAK1 💬 D10871 💬 Filgotinib 6件: 46, 53, 96, 97, 222, 271 💬
38 Influenza A 💬
1件: JAK1 💬 D10944 💬 Itacitinib 5件: 46, 51, 60, 97, 228 💬
39 Influenza A 💬
1件: JAK1 💬 D10994 💬 Upadacitinib 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
40 Influenza A 💬
2件: JAK1, JAK2 💬 D10308 💬 Baricitinib 13件: 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
41 Influenza A 💬
2件: JAK1, JAK2 💬 D10653 💬 Peficitinib 1件: 46 💬
42 Influenza A 💬
2件: JAK1, JAK2 💬 D09959 💬 Ruxolitinib 1件: 228 💬
43 Influenza A 💬
3件: JAK1, JAK2, TYK2 💬 D09970 💬 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
44 Influenza A 💬
2件: MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib 1件: 34 💬
45 Influenza A 💬
2件: MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib 1件: 280 💬
46 Influenza A 💬
2件: MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib 1件: 34 💬
47 Influenza A 💬
2件: MAP2K1, MAP2K2 💬 D10175 💬 Trametinib 4件:  2 , 34, 279, 280 💬
48 Influenza A 💬
1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
49 Influenza A 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
50 Influenza A 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
51 Influenza A 💬
1件: PLG 💬 D00160 💬 Aminocaproic acid 1件: 70 💬
52 Influenza A 💬
1件: PLG 💬 D01136 💬 Tranexamic acid 6件: 46, 70, 215, 227, 288, 299 💬
53 Influenza A 💬
1件: PML 💬 D00094 💬 Tretinoin 6件:  2 , 62, 63, 75, 94, 231 💬
54 Influenza A 💬
1件: RAF1 💬 D06272 💬 Sorafenib 2件: 34, 86 💬
55 Influenza A 💬
1件: RAF1 💬 D08524 💬 Sorafenib 2件: 34, 86 💬
56 Influenza A 💬
1件: RELA 💬 D12181 💬 Edasalonexent 1件: 113 💬
57 Influenza A 💬
1件: TLR7 💬 D02500 💬 Imiquimod 2件: 34, 51 💬
58 Influenza A 💬
1件: TNF 💬 D02597 💬 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
59 Influenza A 💬
1件: TNF 💬 D03441 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
60 Influenza A 💬
1件: TNF 💬 D00742 💬 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
61 Influenza A 💬
1件: TNF 💬 D04358 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
62 Influenza A 💬
1件: TNF 💬 D02598 💬 Infliximab 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
63 Influenza A 💬
1件: TNF 💬 D04687 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
64 Influenza A 💬
1件: TNF 💬 D09944 💬 Ozoralizumab 1件: 46 💬
65 Influenza A 💬
1件: TNF 💬 D05393 💬 Pegsunercept 1件: 46 💬
66 Influenza A 💬
1件: TNF 💬 D00754 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
67 Influenza A 💬
1件: TYK2 💬 D11817 💬 Deucravacitinib 2件: 96, 97 💬
68 Influenza A 💬
1件: XPO1 💬 D11222 💬 Selinexor 1件: 28 💬