Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Pathogenic Escherichia coli infection 💬
1件: ABL1 💬 D01441 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
2 Pathogenic Escherichia coli infection 💬
1件: ABL1 💬 D08066 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
3 Pathogenic Escherichia coli infection 💬
1件: ABL1 💬 D08953 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬
4 Pathogenic Escherichia coli infection 💬
3件: ABL1, FYN, SRC 💬 D03658 💬 Dasatinib 2件: 51, 85 💬
5 Pathogenic Escherichia coli infection 💬
3件: ABL1, FYN, SRC 💬 D06414 💬 Dasatinib 2件: 51, 85 💬
6 Pathogenic Escherichia coli infection 💬
2件: ABL1, SRC 💬 D03252 💬 Bosutinib 2件:  2 , 67 💬
7 Pathogenic Escherichia coli infection 💬
2件: ABL1, SRC 💬 D09664 💬 Saracatinib 3件:  6 , 89, 272 💬
8 Pathogenic Escherichia coli infection 💬
1件: CASP9 💬 D11195 💬 Rimiducid 6件: 19, 60, 65, 284, 285, 326 💬
9 Pathogenic Escherichia coli infection 💬
1件: F2 💬 D09707 💬 Dabigatran 4件: 51, 85, 91, 124 💬
10 Pathogenic Escherichia coli infection 💬
1件: F2 💬 D07144 💬 Dabigatran etexilate 1件: 51 💬
11 Pathogenic Escherichia coli infection 💬
1件: F2 💬 D06410 💬 Thrombomodulin Alfa 1件: 85 💬
12 Pathogenic Escherichia coli infection 💬
1件: IL1B 💬 D09315 💬 Canakinumab 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
13 Pathogenic Escherichia coli infection 💬
1件: IL1B 💬 D09911 💬 Gevokizumab 4件: 41, 50, 56, 269 💬
14 Pathogenic Escherichia coli infection 💬
1件: IL1B 💬 D06635 💬 Rilonacept 4件: 51, 106, 107, 266 💬
15 Pathogenic Escherichia coli infection 💬
3件: IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
16 Pathogenic Escherichia coli infection 💬
1件: IL1R1 💬 D02934 💬 Anakinra 19件:  2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
17 Pathogenic Escherichia coli infection 💬
1件: IL6 💬 D09669 💬 Siltuximab 2件: 28, 331 💬
18 Pathogenic Escherichia coli infection 💬
1件: IL6 💬 D10080 💬 Sirukumab 2件: 41, 46 💬
19 Pathogenic Escherichia coli infection 💬
2件: IL6, TNF 💬 D08976 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
20 Pathogenic Escherichia coli infection 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod 2件: 113, 222 💬
21 Pathogenic Escherichia coli infection 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod 1件:  8  💬
22 Pathogenic Escherichia coli infection 💬
1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
23 Pathogenic Escherichia coli infection 💬
1件: RELA 💬 D12181 💬 Edasalonexent 1件: 113 💬
24 Pathogenic Escherichia coli infection 💬
2件: ROCK1, ROCK2 💬 D07941 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
25 Pathogenic Escherichia coli infection 💬
1件: ROCK2 💬 D11815 💬 Belumosudil 1件: 51 💬
26 Pathogenic Escherichia coli infection 💬
1件: TNF 💬 D02597 💬 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
27 Pathogenic Escherichia coli infection 💬
1件: TNF 💬 D03441 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
28 Pathogenic Escherichia coli infection 💬
1件: TNF 💬 D00742 💬 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
29 Pathogenic Escherichia coli infection 💬
1件: TNF 💬 D04358 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
30 Pathogenic Escherichia coli infection 💬
1件: TNF 💬 D02598 💬 Infliximab 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
31 Pathogenic Escherichia coli infection 💬
1件: TNF 💬 D04687 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
32 Pathogenic Escherichia coli infection 💬
1件: TNF 💬 D09944 💬 Ozoralizumab 1件: 46 💬
33 Pathogenic Escherichia coli infection 💬
1件: TNF 💬 D05393 💬 Pegsunercept 1件: 46 💬
34 Pathogenic Escherichia coli infection 💬
1件: TNF 💬 D00754 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
35 Pathogenic Escherichia coli infection 💬
9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D11595 💬 Belantamab mafodotin 1件: 28 💬
36 Pathogenic Escherichia coli infection 💬
9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D09587 💬 Brentuximab vedotin 2件: 49, 51 💬
37 Pathogenic Escherichia coli infection 💬
9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D00570 💬 Colchicine 7件:  2 , 42, 46, 56, 93, 210, 266 💬
38 Pathogenic Escherichia coli infection 💬
9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D00491 💬 Paclitaxel 2件: 46, 85 💬
39 Pathogenic Escherichia coli infection 💬
9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D05333 💬 Paclitaxel 2件: 46, 85 💬
40 Pathogenic Escherichia coli infection 💬
9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D01068 💬 Vinblastine 2件: 34, 65 💬
41 Pathogenic Escherichia coli infection 💬
9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D08675 💬 Vinblastine 2件: 34, 65 💬
42 Pathogenic Escherichia coli infection 💬
9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D02197 💬 Vincristine 4件: 26, 34, 65, 331 💬
43 Pathogenic Escherichia coli infection 💬
9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D08679 💬 Vincristine 4件: 26, 34, 65, 331 💬