Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Non-small cell lung cancer 💬
1件: ALK 💬 D10866 💬 Brigatinib 1件: 34 💬
2 Non-small cell lung cancer 💬
1件: ALK 💬 D09731 💬 Crizotinib 1件: 34 💬
3 Non-small cell lung cancer 💬
1件: BRAF 💬 D10064 💬 Dabrafenib 1件: 34 💬
4 Non-small cell lung cancer 💬
3件: BRAF, RAF1, RET 💬 D06272 💬 Sorafenib 2件: 34, 86 💬
5 Non-small cell lung cancer 💬
3件: BRAF, RAF1, RET 💬 D08524 💬 Sorafenib 2件: 34, 86 💬
6 Non-small cell lung cancer 💬
1件: CASP9 💬 D11195 💬 Rimiducid 6件: 19, 60, 65, 284, 285, 326 💬
7 Non-small cell lung cancer 💬
2件: CDK4, CDK6 💬 D10688 💬 Abemaciclib 1件: 34 💬
8 Non-small cell lung cancer 💬
1件: EGFR 💬 D03455 💬 Cetuximab 5件: 34, 51, 86, 89, 331 💬
9 Non-small cell lung cancer 💬
1件: EGFR 💬 D04023 💬 Erlotinib 1件: 94 💬
10 Non-small cell lung cancer 💬
1件: EGFR 💬 D07907 💬 Erlotinib 1件: 94 💬
11 Non-small cell lung cancer 💬
1件: EGFR 💬 D01977 💬 Gefitinib 1件: 75 💬
12 Non-small cell lung cancer 💬
1件: EGFR 💬 D11251 💬 Icotinib 1件: 34 💬
13 Non-small cell lung cancer 💬
2件: EGFR, ERBB2 💬 D04024 💬 Lapatinib 3件: 34, 74, 75 💬
14 Non-small cell lung cancer 💬
2件: EGFR, ERBB2 💬 D08108 💬 Lapatinib 3件: 34, 74, 75 💬
15 Non-small cell lung cancer 💬
2件: EGFR, ERBB2 💬 D11772 💬 Tesevatinib 1件: 67 💬
16 Non-small cell lung cancer 💬
1件: JAK3 💬 D10653 💬 Peficitinib 1件: 46 💬
17 Non-small cell lung cancer 💬
1件: JAK3 💬 D09970 💬 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
18 Non-small cell lung cancer 💬
2件: MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib 1件: 34 💬
19 Non-small cell lung cancer 💬
2件: MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib 1件: 280 💬
20 Non-small cell lung cancer 💬
2件: MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib 1件: 34 💬
21 Non-small cell lung cancer 💬
2件: MAP2K1, MAP2K2 💬 D10175 💬 Trametinib 4件:  2 , 34, 279, 280 💬
22 Non-small cell lung cancer 💬
1件: MET 💬 D10062 💬 Cabozantinib 1件: 34 💬
23 Non-small cell lung cancer 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
24 Non-small cell lung cancer 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
25 Non-small cell lung cancer 💬
1件: RARB 💬 D04162 💬 Fenretinide 1件: 299 💬
26 Non-small cell lung cancer 💬
1件: RARB 💬 D00348 💬 Isotretinoin 4件: 36, 39, 159, 160 💬
27 Non-small cell lung cancer 💬
1件: RARB 💬 D00094 💬 Tretinoin 6件:  2 , 62, 63, 75, 94, 231 💬
28 Non-small cell lung cancer 💬
1件: RARB 💬 D06543 💬 Vitamin A 3件: 13, 53, 90 💬
29 Non-small cell lung cancer 💬
4件: RARB, RXRA, RXRB, RXRG 💬 D02754 💬 Acitretin 1件: 37 💬
30 Non-small cell lung cancer 💬
4件: RARB, RXRA, RXRB, RXRG 💬 D02815 💬 Alitretinoin 1件: 49 💬
31 Non-small cell lung cancer 💬
1件: RET 💬 D06402 💬 Sunitinib 2件: 28, 34 💬
32 Non-small cell lung cancer 💬
1件: RET 💬 D08552 💬 Sunitinib 2件: 28, 34 💬
33 Non-small cell lung cancer 💬
3件: RXRA, RXRB, RXRG 💬 D03106 💬 Bexarotene 2件: 13, 75 💬
34 Small cell lung cancer 💬
1件: BCL2 💬 D10679 💬 Venetoclax 1件: 28 💬
35 Small cell lung cancer 💬
1件: CASP9 💬 D11195 💬 Rimiducid 6件: 19, 60, 65, 284, 285, 326 💬
36 Small cell lung cancer 💬
2件: CDK4, CDK6 💬 D10688 💬 Abemaciclib 1件: 34 💬
37 Small cell lung cancer 💬
1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
38 Small cell lung cancer 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
39 Small cell lung cancer 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
40 Small cell lung cancer 💬
1件: PTGS2 💬 D01545 💬 Aceclofenac 1件: 46 💬
41 Small cell lung cancer 💬
1件: PTGS2 💬 D00217 💬 Acetaminophen 18件:  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬
42 Small cell lung cancer 💬
1件: PTGS2 💬 D00109 💬 Acetylsalicylic acid 15件: 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬
43 Small cell lung cancer 💬
1件: PTGS2 💬 D00567 💬 Celecoxib 10件:  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
44 Small cell lung cancer 💬
1件: PTGS2 💬 D00903 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
45 Small cell lung cancer 💬
1件: PTGS2 💬 D00904 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
46 Small cell lung cancer 💬
1件: PTGS2 💬 D07816 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
47 Small cell lung cancer 💬
1件: PTGS2 💬 D00130 💬 Diflunisal 1件: 28 💬
48 Small cell lung cancer 💬
1件: PTGS2 💬 D00315 💬 Etodolac 1件: 46 💬
49 Small cell lung cancer 💬
1件: PTGS2 💬 D03710 💬 Etoricoxib 2件: 46, 271 💬
50 Small cell lung cancer 💬
1件: PTGS2 💬 D00330 💬 Flurbiprofen 3件: 13, 21, 46 💬
51 Small cell lung cancer 💬
1件: PTGS2 💬 D01475 💬 Flurbiprofen 3件: 13, 21, 46 💬
52 Small cell lung cancer 💬
1件: PTGS2 💬 D02290 💬 Flurbiprofen 3件: 13, 21, 46 💬
53 Small cell lung cancer 💬
1件: PTGS2 💬 D00126 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬
54 Small cell lung cancer 💬
1件: PTGS2 💬 D01122 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬
55 Small cell lung cancer 💬
1件: PTGS2 💬 D04490 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬
56 Small cell lung cancer 💬
1件: PTGS2 💬 D06606 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬
57 Small cell lung cancer 💬
1件: PTGS2 💬 D00141 💬 Indomethacin 3件: 225, 271, 298 💬
58 Small cell lung cancer 💬
1件: PTGS2 💬 D01565 💬 Indomethacin 3件: 225, 271, 298 💬
59 Small cell lung cancer 💬
1件: PTGS2 💬 D02110 💬 Indomethacin 3件: 225, 271, 298 💬
60 Small cell lung cancer 💬
1件: PTGS2 💬 D00132 💬 Ketoprofen 1件: 46 💬
61 Small cell lung cancer 💬
1件: PTGS2 💬 D00813 💬 Ketorolac 2件: 70, 226 💬
62 Small cell lung cancer 💬
1件: PTGS2 💬 D08104 💬 Ketorolac 2件: 70, 226 💬
63 Small cell lung cancer 💬
1件: PTGS2 💬 D08149 💬 Loxoprofen 2件: 46, 271 💬
64 Small cell lung cancer 💬
1件: PTGS2 💬 D03714 💬 Lumiracoxib 1件: 46 💬
65 Small cell lung cancer 💬
1件: PTGS2 💬 D00969 💬 Meloxicam 4件: 46, 49, 271, 296 💬
66 Small cell lung cancer 💬
1件: PTGS2 💬 D00118 💬 Naproxen 4件: 13, 46, 107, 271 💬
67 Small cell lung cancer 💬
1件: PTGS2 💬 D01049 💬 Nimesulide 1件: 46 💬
68 Small cell lung cancer 💬
1件: PTGS2 💬 D03716 💬 Parecoxib 2件: 46, 271 💬
69 Small cell lung cancer 💬
1件: PTGS2 💬 D00568 💬 Rofecoxib 1件: 46 💬
70 Small cell lung cancer 💬
1件: PTGS2 💬 D00428 💬 Salsalate 1件:  5  💬
71 Small cell lung cancer 💬
1件: PTGS2 💬 D00120 💬 Sulindac 1件: 206 💬
72 Small cell lung cancer 💬
1件: PTGS2 💬 D01183 💬 Tolfenamic acid 1件:  5  💬
73 Small cell lung cancer 💬
1件: PTGS2 💬 D02709 💬 Valdecoxib 1件: 46 💬
74 Small cell lung cancer 💬
1件: RARB 💬 D04162 💬 Fenretinide 1件: 299 💬
75 Small cell lung cancer 💬
1件: RARB 💬 D00348 💬 Isotretinoin 4件: 36, 39, 159, 160 💬
76 Small cell lung cancer 💬
1件: RARB 💬 D00094 💬 Tretinoin 6件:  2 , 62, 63, 75, 94, 231 💬
77 Small cell lung cancer 💬
1件: RARB 💬 D06543 💬 Vitamin A 3件: 13, 53, 90 💬
78 Small cell lung cancer 💬
4件: RARB, RXRA, RXRB, RXRG 💬 D02754 💬 Acitretin 1件: 37 💬
79 Small cell lung cancer 💬
4件: RARB, RXRA, RXRB, RXRG 💬 D02815 💬 Alitretinoin 1件: 49 💬
80 Small cell lung cancer 💬
1件: RELA 💬 D12181 💬 Edasalonexent 1件: 113 💬
81 Small cell lung cancer 💬
3件: RXRA, RXRB, RXRG 💬 D03106 💬 Bexarotene 2件: 13, 75 💬