Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
|---|---|---|---|---|---|
| 1 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
BTK 1件: BTK 💬 |
Acalabrutinib Acalabrutinib 💬 |
Acalabrutinib | 046 2件: 46, 61 💬 💬 |
| 2 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
BTK 1件: BTK 💬 |
Branebrutinib Branebrutinib 💬 |
Branebrutinib | 046 3件: 46, 49, 53 💬 💬 |
| 3 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
BTK 1件: BTK 💬 |
Evobrutinib Evobrutinib 💬 |
Evobrutinib | 013 3件: 13, 46, 49 💬 💬 |
| 4 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
BTK 1件: BTK 💬 |
Fenebrutinib Fenebrutinib 💬 |
Fenebrutinib | 013 1件: 13 💬 💬 |
| 5 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
BTK 1件: BTK 💬 |
Ibrutinib Ibrutinib 💬 |
Ibrutinib | 028 3件: 28, 60, 61 💬 💬 |
| 6 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
BTK 1件: BTK 💬 |
Orelabrutinib Orelabrutinib 💬 |
Orelabrutinib | 013 4件: 13, 49, 61, 63 💬 💬 |
| 7 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
BTK 1件: BTK 💬 |
Remibrutinib Remibrutinib 💬 |
Remibrutinib | 013 2件: 13, 53 💬 💬 |
| 8 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
BTK 1件: BTK 💬 |
Zanubrutinib Zanubrutinib 💬 |
Zanubrutinib | 013 5件: 13, 63, 222, 300, 331 💬 💬 |
| 9 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
CSF1R 1件: CSF1R 💬 |
Pexidartinib Pexidartinib 💬 |
Pexidartinib | 034 1件: 34 💬 💬 |
| 10 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
CSF1R 1件: CSF1R 💬 |
Sunitinib Sunitinib 💬 |
Sunitinib | 028 2件: 28, 34 💬 💬 |
| 11 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
FYN 2件: FYN, LCK 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 2件: 51, 85 💬 💬 |
| 12 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
FYN 2件: FYN, LCK 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 2件: 51, 85 💬 💬 |
| 13 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IFNAR1 2件: IFNAR1, IFNAR2 💬 |
Anifrolumab Anifrolumab 💬 |
Anifrolumab | 046 3件: 46, 49, 53 💬 💬 |
| 14 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IFNAR1 2件: IFNAR1, IFNAR2 💬 |
Interferon alfa Interferon alfa 💬 |
Interferon alfa | 013 6件: 13, 25, 26, 28, 56, 96 💬 💬 |
| 15 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IFNAR1 2件: IFNAR1, IFNAR2 💬 |
Interferon alfa-2a Interferon alfa-2a 💬 |
Interferon alfa-2a | 056 1件: 56 💬 💬 |
| 16 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IFNAR1 2件: IFNAR1, IFNAR2 💬 |
Interferon alfa-2b Interferon alfa-2b 💬 |
Interferon alfa-2b | 025 2件: 25, 34 💬 💬 |
| 17 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IFNAR1 2件: IFNAR1, IFNAR2 💬 |
Interferon beta-1a Interferon beta-1a 💬 |
Interferon beta-1a | 013 4件: 13, 26, 96, 97 💬 💬 |
| 18 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IFNAR1 2件: IFNAR1, IFNAR2 💬 |
Interferon beta-1b Interferon beta-1b 💬 |
Interferon beta-1b | 013 1件: 13 💬 💬 |
| 19 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IFNAR1 2件: IFNAR1, IFNAR2 💬 |
Peginterferon beta-1a Peginterferon beta-1a 💬 |
Peginterferon beta-1a | 013 1件: 13 💬 💬 |
| 20 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IFNG 1件: IFNG 💬 |
Emapalumab Emapalumab 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 💬 |
| 21 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IFNG 1件: IFNG 💬 |
Fontolizumab Fontolizumab 💬 |
Fontolizumab | 046 1件: 46 💬 💬 |
| 22 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
Interferon gamma-1b Interferon gamma-1b 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 💬 |
| 23 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IL1A 1件: IL1A 💬 |
Bermekimab Bermekimab 💬 |
Bermekimab | 051 1件: 51 💬 💬 |
| 24 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IL1A 2件: IL1A, IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 25 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IL1A 3件: IL1A, IL1B, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
| 26 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 27 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IL1B 1件: IL1B 💬 |
Gevokizumab Gevokizumab 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 💬 |
| 28 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IL1R1 1件: IL1R1 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
| 29 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
JAK1 1件: JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 1件: 84 💬 💬 |
| 30 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
JAK1 1件: JAK1 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
| 31 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
JAK1 1件: JAK1 💬 |
Filgotinib Filgotinib 💬 |
Filgotinib | 046 6件: 46, 53, 96, 97, 222, 271 💬 💬 |
| 32 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
JAK1 1件: JAK1 💬 |
Itacitinib Itacitinib 💬 |
Itacitinib | 046 4件: 46, 51, 97, 228 💬 💬 |
| 33 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
JAK1 1件: JAK1 💬 |
Peficitinib Peficitinib 💬 |
Peficitinib | 046 1件: 46 💬 💬 |
| 34 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
JAK1 1件: JAK1 💬 |
Ruxolitinib Ruxolitinib 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 💬 |
| 35 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
JAK1 1件: JAK1 💬 |
Upadacitinib Upadacitinib 💬 |
Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 💬 |
| 36 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
JAK1 2件: JAK1, TYK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
| 37 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
LILRA4 1件: LILRA4 💬 |
Daxdilimab Daxdilimab 💬 |
Daxdilimab | 049 2件: 49, 50 💬 💬 |
| 38 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
MAP2K1 1件: MAP2K1 💬 |
Binimetinib Binimetinib 💬 |
Binimetinib | 034 1件: 34 💬 💬 |
| 39 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
MAP2K1 1件: MAP2K1 💬 |
Cobimetinib Cobimetinib 💬 |
Cobimetinib | 280 1件: 280 💬 💬 |
| 40 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
MAP2K1 1件: MAP2K1 💬 |
Mirdametinib Mirdametinib 💬 |
Mirdametinib | 034 1件: 34 💬 💬 |
| 41 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
MAP2K1 1件: MAP2K1 💬 |
Selumetinib Selumetinib 💬 |
Selumetinib | 034 1件: 34 💬 💬 |
| 42 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
MAP2K1 1件: MAP2K1 💬 |
Trametinib Trametinib 💬 |
Trametinib | 002 4件: 2 , 34, 279, 280 💬 💬 |
| 43 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
MAPK11 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 |
Losmapimod Losmapimod 💬 |
Losmapimod | 113 2件: 113, 222 💬 💬 |
| 44 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
MAPK11 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 |
Neflamapimod Neflamapimod 💬 |
Neflamapimod | 008 1件: 8 💬 💬 |
| 45 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
NFKB1 1件: NFKB1 💬 |
Iguratimod Iguratimod 💬 |
Iguratimod | 046 5件: 46, 51, 53, 271, 300 💬 💬 |
| 46 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
PIK3CA 1件: PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 1件: 138 💬 💬 |
| 47 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 2件: 53, 65 💬 💬 |
| 48 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
PIK3CD 1件: PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 3件: 35, 53, 61 💬 💬 |
| 49 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
PPARG 1件: PPARG 💬 |
Bocidelpar Bocidelpar 💬 |
Bocidelpar | 113 1件: 113 💬 💬 |
| 50 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
PPARG 1件: PPARG 💬 |
Leriglitazone Leriglitazone 💬 |
Leriglitazone | 020 1件: 20 💬 💬 |
| 51 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
PPARG 1件: PPARG 💬 |
Pioglitazone Pioglitazone 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 💬 |
| 52 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
PPARG 1件: PPARG 💬 |
Rosiglitazone Rosiglitazone 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 💬 |
| 53 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
PPARG 1件: PPARG 💬 |
Seladelpar Seladelpar 💬 |
Seladelpar | 093 2件: 93, 94 💬 💬 |
| 54 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
| 55 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Pimecrolimus Pimecrolimus 💬 |
Pimecrolimus | 160 1件: 160 💬 💬 |
| 56 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
| 57 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
| 58 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Voclosporin Voclosporin 💬 |
Voclosporin | 049 2件: 49, 222 💬 💬 |
| 59 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
RELA 1件: RELA 💬 |
Edasalonexent Edasalonexent 💬 |
Edasalonexent | 113 1件: 113 💬 💬 |
| 60 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
SYK 1件: SYK 💬 |
Fostamatinib Fostamatinib 💬 |
Fostamatinib | 046 4件: 46, 49, 61, 66 💬 💬 |
| 61 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TGFB1 2件: TGFB1, TGFB2 💬 |
Fresolimumab Fresolimumab 💬 |
Fresolimumab | 051 3件: 51, 85, 222 💬 💬 |
| 62 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
| 63 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
| 64 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬 |
Etanercept Etanercept 💬 |
Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 💬 |
| 65 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
| 66 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
| 67 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬 |
Lenalidomide Lenalidomide 💬 |
Lenalidomide | 016 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬 💬 |
| 68 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬 |
Ozoralizumab Ozoralizumab 💬 |
Ozoralizumab | 046 1件: 46 💬 💬 |
| 69 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬 |
Pegsunercept Pegsunercept 💬 |
Pegsunercept | 046 1件: 46 💬 💬 |
| 70 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬 |
Pomalidomide Pomalidomide 💬 |
Pomalidomide | 028 5件: 28, 51, 85, 227, 331 💬 💬 |
| 71 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
| 72 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNFSF11 1件: TNFSF11 💬 |
Denosumab Denosumab 💬 |
Denosumab | 046 8件: 46, 50, 70, 93, 95, 96, 274, 299 💬 💬 |
| 73 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TYK2 1件: TYK2 💬 |
Deucravacitinib Deucravacitinib 💬 |
Deucravacitinib | 049 3件: 49, 96, 97 💬 💬 |