Drug Description in Trials / DrugBank / KEGG DRUG /

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1Acetate[1] Acetate---[41] 1, 2, 6, 10, 13, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 171, 206, 222, 224, 225, 227, 235, 251, 265, 288, 298, 299 💬
2Administration of a high dose of desipramine[1] Desipramine[1] Desipramine 💬[2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[1] 156 💬
3Administration of a low dose of desipramine[1] Desipramine[1] Desipramine 💬[2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[1] 156 💬
4ALAC, inulin, FOS, and sodium butyrate[2] Butyric Acid,
Inulin		[1] Inulin 💬--[1] 156 💬
5Alpha-tocotrienol quinone[1] Tocotrienol---[2] 21, 156 💬
6ANA001XHCl (Syntagon) or VEXA-04 (Patheon)----[1] 156 💬
7ANAVEX2-73----[2] 6, 156 💬
8ANAVEX2-73 (blarcamesine)[1] Blarcamesine[1] Blarcamesine 💬[6] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5,
SIGMAR1 💬		[14] Alzheimer disease, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[1] 156 💬
9ANAVEX2-73 oral liquid----[1] 156 💬
10Blarcamesine[1] Blarcamesine[1] Blarcamesine 💬[6] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5,
SIGMAR1 💬		[14] Alzheimer disease, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[1] 156 💬
11Butyrate[1] Butyric Acid---[4] 46, 97, 156, 291 💬
12Calcium[2] Calcium,
Calcium carbonate		[2] Calcium carbonate ,
Calcium carbonate 💬		--[27] 6, 13, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 156, 214, 215, 222, 224, 235, 265, 274, 298, 299 💬
13Cannabidiol[1] Cannabidiol[1] Cannabidiol 💬[2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[18] 6, 8, 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
14Cannabidiol (CBD)[1] Cannabidiol[1] Cannabidiol 💬[2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[7] 6, 13, 140, 144, 145, 156, 158 💬
15Cannabidiolo----[1] 156 💬
16Cannabidiolo (CBD)----[1] 156 💬
17CBD----[13] 2, 6, 8, 13, 36, 46, 51, 140, 144, 145, 156, 158, 206 💬
18CBD - Oral Solution, is known as Epidyolex, and is the approved name[1] Cannabidiol[1] Cannabidiol 💬[2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[1] 156 💬
19CBD - Solution Orale, conosciuto come Epidiolex, questo è il nome approvato negli Stati Uniti[1] Cannabidiol[1] Cannabidiol 💬[2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[1] 156 💬
20CBD Oral solution, is known as Epidyolex and is the approved name in the EU[1] Cannabidiol[1] Cannabidiol 💬[2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[1] 156 💬
21CBD soluzione orale nota come Epidyolex e con tale nome è stato approvato in UE[1] Cannabidiol[1] Cannabidiol 💬[2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[1] 156 💬
22Creatine[1] Creatine---[11] 1, 2, 5, 6, 8, 46, 49, 50, 113, 156, 201 💬
23Creatine Monohydrate[1] Creatine---[4] 2, 8, 113, 156 💬
24Desipramine[1] Desipramine[1] Desipramine 💬[2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[2] 120, 156 💬
25Dextromethorphan[1] Dextromethorphan[1] Dextromethorphan 💬[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156 💬
26Donepezil[1] Donepezil[1] Donepezil 💬[1] ACHE 💬[2] Cholinergic synapse, Glycerophospholipid metabolism 💬[9] 5, 6, 13, 46, 78, 124, 127, 156, 206 💬
27Donepezil Hydrochloride[1] Donepezil[1] Donepezil 💬[1] ACHE 💬[2] Cholinergic synapse, Glycerophospholipid metabolism 💬[3] 6, 124, 156 💬
28EMD 128130----[2] 6, 156 💬
29EPI-743----[3] 21, 156, 337 💬
30Epidyolex[1] Cannabidiol[1] Cannabidiol 💬[2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[1] 156 💬
31Epidyolex and is the approved name in the EU[1] Cannabidiol[1] Cannabidiol 💬[2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[1] 156 💬
32FINGOLIMOD[1] Fingolimod[1] Fingolimod 💬[1] S1PR1 💬[3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[3] 13, 14, 156 💬
33Fingolimod (FTY720)[1] Fingolimod[1] Fingolimod 💬[1] S1PR1 💬[3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[2] 13, 156 💬
34Glatiramer[1] Glatiramer---[4] 2, 13, 96, 156 💬
35GLATIRAMER ACETATE[2] Acetate,
Glatiramer		---[3] 13, 96, 156 💬
36Glatiramer Acetate (Copaxone®)[2] Acetate,
Glatiramer		---[2] 13, 156 💬
37GWP42003-P----[5] 140, 144, 145, 156, 158 💬
38Human insulin[1] Insulin human[1] Insulin human 💬[1] INSR 💬[22] AMPK signaling pathway, Adherens junction, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Diabetic cardiomyopathy, FoxO signaling pathway, HIF-1 signaling pathway, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Non-alcoholic fatty liver disease, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus, cGMP-PKG signaling pathway, mTOR signaling pathway 💬[2] 96, 156 💬
39Inulin[1] Inulin[1] Inulin 💬--[4] 6, 96, 156, 299 💬
40KETAMINE[1] Ketamine[1] Ketamine 💬[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[6] 6, 13, 70, 113, 156, 215 💬
41Lactobacillus plantarum[1] Lactobacillus plantarum---[3] 6, 97, 156 💬
42Lovastatin[1] Lovastatin[1] Lovastatin 💬[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
43NNZ-2566----[2] 156, 206 💬
44Probiotic-Lactobacillus plantarum PS128[1] Lactobacillus plantarum---[1] 156 💬
45Recombinant Human Insulin Growth Factor 1 (rhIGF-1)[1] Insulin human[1] Insulin human 💬[1] INSR 💬[22] AMPK signaling pathway, Adherens junction, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Diabetic cardiomyopathy, FoxO signaling pathway, HIF-1 signaling pathway, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Non-alcoholic fatty liver disease, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus, cGMP-PKG signaling pathway, mTOR signaling pathway 💬[1] 156 💬
46Rett-T----[1] 156 💬
47RhIGF-1----[1] 156 💬
48Risperidone[1] Risperidone[1] Risperidone 💬[2] DRD2,
HTR2A 💬		[11] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬[5] 8, 156, 179, 187, 206 💬
49SARIZOTAN[1] Sarizotan---[2] 6, 156 💬
50Sarizotan Hydrochloride[1] Sarizotan---[2] 6, 156 💬
51Sodium butyrate and zinc oxide[2] Butyric Acid,
Zinc oxide		[1] Zinc oxide 💬--[1] 156 💬
52Tocotrienol[1] Tocotrienol---[3] 21, 156, 299 💬
53TOPIRAMATE[1] Topiramate[1] Topiramate 💬[36] CA2,
CA4,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ,
GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[53] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 6, 97, 140, 144, 156, 193 💬
54Tridecanoic Acid----[1] 156 💬
55Triheptanoin[1] Triheptanoin[1] Triheptanoin 💬--[10] 2, 8, 65, 149, 156, 248, 256, 257, 317, 324 💬
56Trofinetide[1] Trofinetide[1] Trofinetide 💬--[1] 156 💬
57TSHA-102----[1] 156 💬
58VYNT-0126----[1] 156 💬
59Zinc oxide[1] Zinc oxide[1] Zinc oxide 💬--[1] 156 💬