Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Abacavir [4] Abacavir; Abacavir sulfate; Triumeq; Ziagen[1] Abacavir 💬--[5] 2, 135, 256, 265, 325 💬
2 Acetate [1] Acetate---[41] 1, 2, 6, 10, 13, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 171, 206, 222, 224, 225, 227, 235, 251, 265, 288, 298, 299 💬
3 Acetylcarnitine [2] Acetyl-L-carnitine; Acetylcarnitine---[3] 2, 265, 298 💬
4 Acipimox [1] Acipimox[1] Acipimox 💬--[2] 78, 265 💬
5 Amprenavir [1] Amprenavir[1] Amprenavir 💬--[1] 265 💬
6 ANX-510 [0] ---[2] 265, 288 💬
7 Aramchol [1] Aramchol---[1] 265 💬
8 Atazanavir [2] Atazanavir; Reyataz[1] Atazanavir 💬--[1] 265 💬
9 Atorvastatin [3] Atorvastatin; Atorvastatin Calcium; Lipitor[1] Atorvastatin 💬[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[19] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
10 Baricitinib [2] Baricitinib; OLUMIANT[1] Baricitinib 💬[2] JAK1,
JAK2 💬		[35] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[13] 2, 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
11 Berberine [1] Berberine---[2] 97, 265 💬
12 Caffeine [1] Caffeine[2] Caffeine ,
Caffeine hydrate 💬		[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 21, 46, 78, 96, 97, 265 💬
13 Calcium [2] Calcio; Calcium---[27] 6, 13, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 156, 214, 215, 222, 224, 235, 265, 274, 298, 299 💬
14 Cholic Acid [1] Cholic Acid[1] Cholic acid 💬[1] NR1H4 💬[1] Bile secretion 💬[4] 20, 234, 265, 310 💬
15 Didanosine [1] Didanosine[1] Didanosine 💬--[2] 25, 265 💬
16 Diosmin [1] DIOSMIN[1] Diosmin 💬--[3] 46, 97, 265 💬
17 Dolutegravir [2] Dolutegravir; Triumeq[1] Dolutegravir 💬--[2] 2, 265 💬
18 Doravirine [1] Doravirine[1] Doravirine 💬--[1] 265 💬
19 Efavirenz [2] Efavirenz; SUSTIVA[1] Efavirenz 💬--[1] 265 💬
20 Emtricitabine [2] Emtricitabine; TRUVADA[1] Emtricitabine 💬--[4] 25, 93, 265, 325 💬
21 Enfuvirtide [1] Enfuvirtide[1] Enfuvirtide 💬--[2] 25, 265 💬
22 Fenofibrate [1] Fenofibrate[1] Fenofibrate 💬[1] PPARA 💬[10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[6] 8, 79, 93, 94, 97, 265 💬
23 Gemcabene [1] Gemcabene---[2] 79, 265 💬
24 Indinavir [1] Indinavir[1] Indinavir 💬--[1] 265 💬
25 Lamivudine [4] COMBIVIR; Epivir; Lamivudine; Triumeq[1] Lamivudine 💬--[8] 2, 26, 42, 46, 135, 256, 265, 325 💬
26 Leptin [1] Leptin---[2] 6, 265 💬
27 Levocarnitine [4] Carnitine; L-Carnitine; Levocarnitine; Xyzal[1] Levocarnitine 💬--[11] 3, 5, 13, 53, 58, 86, 96, 97, 265, 298, 316 💬
28 Lopinavir [2] Kaletra; Lopinavir[1] Lopinavir 💬--[2] 93, 265 💬
29 Mecasermin [3] Increlex; MECASERMIN; MECASERMINA[1] Mecasermin 💬[2] GHR,
IGF1R 💬		[33] AMPK signaling pathway, Adherens junction, Autophagy - animal, Breast cancer, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Focal adhesion, FoxO signaling pathway, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, JAK-STAT signaling pathway, Long-term depression, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Melanoma, Neuroactive ligand-receptor interaction, Oocyte meiosis, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, mTOR signaling pathway 💬[6] 65, 78, 96, 168, 265, 299 💬
30 Metformin [5] Metformin; Metformin HCl; Metformin hydrochloride; METFORMINA; Metformine[1] Metformin 💬[2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[25] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
31 Metreleptin [3] METRELEPTIN; Myalept; R-metHuLeptin[1] Metreleptin 💬[1] LEPR 💬[6] AMPK signaling pathway, Adipocytokine signaling pathway, Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, Non-alcoholic fatty liver disease 💬[1] 265 💬
32 Nelfinavir [1] Nelfinavir[1] Nelfinavir 💬--[3] 49, 265, 331 💬
33 Nevirapine [1] Nevirapine[1] Nevirapine 💬--[1] 265 💬
34 Obeticholic acid [4] 6-ECDCA; 6-ethylchenodeoxycholic acid; OBETICHOLIC ACID; Ocaliva[1] Obeticholic acid 💬[1] NR1H4 💬[1] Bile secretion 💬[3] 93, 265, 296 💬
35 Pegvisomant [1] Pegvisomant[1] Pegvisomant 💬[1] GHR 💬[5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[2] 78, 265 💬
36 Pioglitazone [1] Pioglitazone[1] Pioglitazone 💬[1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
37 Pravastatin [2] Pravastatin; Pravastatin sodium[1] Pravastatin 💬[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
38 Pyrimethamine [2] Daraprim; Pyrimethamine[1] Pyrimethamine 💬--[12] 2, 4, 6, 13, 19, 46, 51, 63, 65, 96, 97, 265 💬
39 Raltegravir [2] ISENTRESS; Raltegravir[1] Raltegravir 💬--[4] 13, 26, 93, 265 💬
40 Riboflavin [2] Riboflavin; Vitamin B2[1] Riboflavin 💬--[7] 38, 46, 96, 97, 162, 168, 265 💬
41 Ritonavir [2] Norvir; Ritonavir[1] Ritonavir 💬--[3] 2, 86, 265 💬
42 Rosiglitazone [2] Rosiglitazone; Rosiglitazone maleate[1] Rosiglitazone 💬[1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[5] 46, 75, 97, 222, 265 💬
43 Saquinavir [1] Saquinavir[1] Saquinavir 💬--[2] 86, 265 💬
44 Setmelanotide [1] Setmelanotide[1] Setmelanotide 💬[1] MC4R 💬[1] Neuroactive ligand-receptor interaction 💬[2] 202, 265 💬
45 Simvastatin [3] Simvastatin; Simvastatina; Simvastatine[1] Simvastatin 💬[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[21] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
46 Somatotropin [17] Genotropin; Growth hormone; Human growth hormone; Humatrope; Norditropin; Norditropin SimpleXx; NUTROPIN; Nutropin AQ; NutropinAq; OMNITROPE; RECOMBINANT HUMAN GROWTH HORMONE; RhGH; SAIZEN; Somatotropin; SOMATROPIN; SOMATROPINA; Zomacton---[25] 2, 3, 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 246, 265, 274, 276, 299, 337 💬
47 Stavudine [1] Stavudine[1] Stavudine 💬--[1] 265 💬
48 Sulfate ion [1] Sulfate---[27] 2, 3, 6, 11, 13, 26, 28, 34, 36, 46, 49, 53, 60, 64, 66, 85, 86, 96, 111, 218, 222, 224, 226, 265, 296, 297, 299 💬
49 Tenofovir [1] Tenofovir[1] Tenofovir 💬--[6] 2, 13, 25, 93, 265, 325 💬
50 Tenofovir disoproxil [4] Tenofovir; Tenofovir disoproxil; Tenofovir Disoproxil Fumarate; TRUVADA---[2] 93, 265 💬
51 Tesamorelin [2] GHRH; Tesamorelin[1] Tesamorelin 💬[1] GHRHR 💬[2] Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction 💬[2] 78, 265 💬
52 Thiamine [2] Thiamine; Vitamin B1[1] Thiamine 💬--[4] 8, 93, 145, 265 💬
53 Tipranavir [1] Tipranavir[1] Tipranavir 💬--[1] 265 💬
54 Volanesorsen [1] Volanesorsen[1] Volanesorsen 💬[1] APOC3 💬[2] Cholesterol metabolism, PPAR signaling pathway 💬[1] 265 💬
55 Zidovudine [3] COMBIVIR; Retrovir; Zidovudine[1] Zidovudine 💬--[7] 25, 26, 94, 135, 265, 325, 331 💬