1 |
Acetate
| [1] Acetate Acetate | - | - | - | [41] 1 1, 2, 6, 10, 13, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 171, 206, 222, 224, 225, 227, 235, 251, 265, 288, 298, 299 |
2 |
Acetylsalicylic acid
| [2] Acetylsalicylic Acid Acetylsalicylic Acid; Aspirin | [1] D00109
D00109
| [2] PTGS1 PTGS1, PTGS2 💬 | [23] Alzheimer disease Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬 | [14] 13 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 |
3 |
Arginine
| [6] Arginina Arginina; Arginine; L-Arg; L-Arginin; L-arginine; R-Gene | [1] D02982
D02982
| - | - | [12] 46 46, 58, 65, 67, 78, 96, 97, 98, 113, 210, 251, 299 |
4 |
Ataluren
| [2] ATALUREN ATALUREN; Translarna | [1] D09323
D09323
| - | - | [6] 19 19, 113, 140, 246, 299, 329 |
5 |
ATYR-1940
| [1] ATYR1940 ATYR1940 | - | - | - | [1] 113 113 |
6 |
Bisoprolol
| [2] Bisoprolol Bisoprolol; Bisoprolol Fumarate | [1] D02342
D02342
| [1] ADRB1 ADRB1 💬 | [11] Adrenergic signaling in cardiomyocytes Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬 | [4] 58 58, 67, 86, 113 |
7 |
BLS-M22
| [1] BLS-M22 BLS-M22 | - | - | - | [1] 113 113 |
8 |
BMN-044
| [0] | - | - | - | [1] 113 113 |
9 |
BMN-045
| [2] BMN 045 BMN 045; PRO045 | - | - | - | [1] 113 113 |
10 |
BMN-053
| [1] BMN053 BMN053 | - | - | - | [1] 113 113 |
11 |
Bocidelpar
| [1] Bocidelpar Bocidelpar | [1] D12242
D12242
| [1] PPARG PPARG 💬 | [11] AMPK signaling pathway AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬 | [1] 113 113 |
12 |
Botulinum toxin type A
| [8] Botox Botox; Botulinum toxin A; BOTULINUM TOXIN TYPE A; BTX-A; Dysport; IncobotulinumtoxinA; OnabotulinumtoxinA; Xeomin | [1] D00783
D00783
| [1] SNAP25 SNAP25 💬 | [2] Insulin secretion Insulin secretion, Synaptic vesicle cycle 💬 | [14] 2 2, 5, 6, 7, 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 |
13 |
Calcifediol
| [2] 25-Hydroxyvitamin D3 25-Hydroxyvitamin D3; CALCIFEDIOL | [1] D00122
D00122
| [1] VDR VDR 💬 | [5] Chemical carcinogenesis - receptor activation Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬 | [2] 113 113, 299 |
14 |
Canakinumab
| [2] CANAKINUMAB CANAKINUMAB; Ilaris | [1] D09315
D09315
| [1] IL1B IL1B 💬 | [44] AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alcoholic liver disease, Alzheimer disease, Amoebiasis, Antifolate resistance, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Herpes simplex virus 1 infection, Human cytomegalovirus infection, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, Shigellosis, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Tuberculosis, Type I diabetes mellitus, Yersinia infection 💬 | [10] 46 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 |
15 |
CAP-1002
| [1] CAP-1002 CAP-1002 | - | - | - | [1] 113 113 |
16 |
Carvedilol
| [1] Carvedilol Carvedilol | [1] D00255
D00255
| [5] ADRA1A ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 | [13] AMPK signaling pathway AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬 | [4] 57 57, 86, 113, 210 |
17 |
Casimersen
| [1] CASIMERSEN CASIMERSEN | [1] D11988
D11988
| [1] DMD DMD 💬 | [4] Arrhythmogenic right ventricular cardiomyopathy Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬 | [1] 113 113 |
18 |
Citrulline
| [1] Citrulline Citrulline | - | - | - | [2] 86 86, 113 |
19 |
Creatine
| [1] Creatine Creatine | - | - | - | [11] 1 1, 2, 5, 6, 8, 46, 49, 50, 113, 156, 201 |
20 |
Cyclosporine
| [10] Ciclosporin Ciclosporin; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A; Ikervis; Neoral; RESTASIS | [1] D00184
D00184
| [5] PPP3CA PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 | [33] Alzheimer disease Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬 | [44] 11 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
21 |
Deflazacort
| [1] Deflazacort Deflazacort | [1] D03671
D03671
| [1] NR3C1 NR3C1 💬 | [1] Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction 💬 | [2] 30 30, 113 |
22 |
Dexmedetomidine
| [4] Dexdor Dexdor; DEXMEDETOMIDINA; DEXMEDETOMIDINE; DEXMEDETOMIDINE HYDROCHLORIDE | [1] D00514
D00514
| [3] ADRA2A ADRA2A, ADRA2B, ADRA2C 💬 | [2] Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬 | [14] 2 2, 4, 6, 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 |
23 |
Doconexent
| [2] Docosahexaenoic acid Docosahexaenoic acid; Docosahexanoic Acid | - | - | - | [10] 6 6, 46, 48, 49, 90, 94, 113, 240, 299, 301 |
24 |
Domagrozumab
| [1] PF-06252616 PF-06252616 | [1] D11047
D11047
| [1] MSTN MSTN 💬 | [1] Cytokine-cytokine receptor interaction Cytokine-cytokine receptor interaction 💬 | [1] 113 113 |
25 |
Drisapersen
| [1] Drisapersen Drisapersen | [1] D10114
D10114
| [1] DMD DMD 💬 | [4] Arrhythmogenic right ventricular cardiomyopathy Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬 | [1] 113 113 |
26 |
Edasalonexent
| [1] EDASALONEXENT EDASALONEXENT | [1] D12181
D12181
| [1] RELA RELA 💬 | [76] AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Acute myeloid leukemia, Adipocytokine signaling pathway, Alcoholic liver disease, Alzheimer disease, Amoebiasis, Antifolate resistance, Apoptosis, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Chronic myeloid leukemia, Cocaine addiction, Coronavirus disease - COVID-19, Cytosolic DNA-sensing pathway, Diabetic cardiomyopathy, Epithelial cell signaling in Helicobacter pylori infection, Epstein-Barr virus infection, Fluid shear stress and atherosclerosis, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Longevity regulating pathway, MAPK signaling pathway, Measles, Mitophagy - animal, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prolactin signaling pathway, Prostate cancer, RIG-I-like receptor signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Salmonella infection, Shigellosis, Small cell lung cancer, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Viral carcinogenesis, Yersinia infection, cAMP signaling pathway 💬 | [1] 113 113 |
27 |
Enalapril
| [2] Enalapril Enalapril; Enalapril Maleate | [1] D07892
D07892
| [1] ACE ACE 💬 | [6] Chagas disease Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬 | [6] 19 19, 46, 66, 113, 210, 222 |
28 |
Epicatechin
| [1] Epicatechin Epicatechin | - | - | - | [2] 86 86, 113 |
29 |
Epigallocatechin
| [1] Epigallocatechin Epigallocatechin | - | - | - | [5] 8 8, 13, 28, 85, 113 |
30 |
Epigallocatechin gallate
| [3] EGCG EGCG; Epigallocatechin gallate; Epigallocatechin-3-gallate | - | - | - | [9] 6 6, 8, 13, 17, 28, 85, 113, 206, 299 |
31 |
Eplerenone
| [1] Eplerenone Eplerenone | [1] D01115
D01115
| [1] NR3C2 NR3C2 💬 | [1] Aldosterone-regulated sodium reabsorption Aldosterone-regulated sodium reabsorption 💬 | [4] 75 75, 113, 210, 215 |
32 |
Esomeprazole
| [3] Esomeprazole Esomeprazole; Nexium; Omeprazole | [1] D07917
D07917
| [2] ATP4A ATP4A, ATP4B 💬 | [4] Collecting duct acid secretion Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬 | [8] 13 13, 46, 86, 98, 107, 113, 298, 299 |
33 |
Eteplirsen
| [2] ETEPLIRSEN ETEPLIRSEN; Exondys 51 | [1] D09900
D09900
| [1] DMD DMD 💬 | [4] Arrhythmogenic right ventricular cardiomyopathy Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬 | [1] 113 113 |
34 |
Ezutromid
| [1] Ezutromid Ezutromid | - | - | - | [1] 113 113 |
35 |
Filgrastim
| [7] Filgrastim Filgrastim; Filgrastim Hexal; G-CSF; Granulocyte Colony Stimulating Factor; Neupogen; TEVAGRASTIM; ZARZIO | [1] D03235
D03235
| [1] CSF3R CSF3R 💬 | [5] Cytokine-cytokine receptor interaction Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬 | [35] 2 2, 6, 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 |
36 |
Fordadistrogene movaparvovec
| [1] Fordadistrogene movaparvovec Fordadistrogene movaparvovec | - | - | - | [1] 113 113 |
37 |
Gentamicin
| [2] Gentamicin Gentamicin; Gentamicin Sulfate | [1] D08013
D08013
| - | - | [3] 36 36, 113, 299 |
38 |
Givinostat
| [1] GIVINOSTAT GIVINOSTAT | - | - | - | [2] 107 107, 113 |
39 |
Gold
| [1] Gold Gold | - | - | - | [43] 2 2, 5, 6, 13, 17, 34, 35, 46, 49, 50, 53, 58, 63, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 137, 158, 162, 167, 171, 193, 218, 222, 224, 226, 227, 230, 271, 291, 296, 298, 310, 318 |
40 |
Golodirsen
| [2] GOLODIRSEN GOLODIRSEN; Vyondys 53 | [1] D11707
D11707
| [1] DMD DMD 💬 | [4] Arrhythmogenic right ventricular cardiomyopathy Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬 | [1] 113 113 |
41 |
Guanidine
| [1] Guanidine Guanidine | - | - | - | [1] 113 113 |
42 |
Human Umbilical Cord Mesenchymal Stem Cells
| [4] Human Umbilical Cord Mesenchymal Stem Cells Human Umbilical Cord Mesenchymal Stem Cells; Mesenchymal Stromal Cells; UC-MSCs; WJ-MSCs | - | - | - | [13] 2 2, 13, 36, 46, 49, 51, 60, 96, 97, 107, 113, 274, 284 |
43 |
Ibuprofen
| [2] IBUPROFEN IBUPROFEN; IBUPROFEN 200MG | [1] D00126
D00126
| [2] PTGS1 PTGS1, PTGS2 💬 | [23] Alzheimer disease Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬 | [7] 13 13, 46, 65, 107, 113, 271, 299 |
44 |
Icosapent
| [2] Eicosapentaenoic acid Eicosapentaenoic acid; Icosapent | [1] D08061
D08061
| - | - | [11] 8 8, 46, 48, 49, 96, 97, 113, 296, 297, 301, 338 |
45 |
Idebenone
| [2] Idebenone Idebenone; Raxone | [1] D01750
D01750
| - | - | [6] 6 6, 8, 13, 18, 113, 302 |
46 |
Ifetroban
| [1] Ifetroban Ifetroban | [1] D04500
D04500
| [1] TBXA2R TBXA2R 💬 | [3] Calcium signaling pathway Calcium signaling pathway, Neuroactive ligand-receptor interaction, Platelet activation 💬 | [2] 85 85, 113 |
47 |
Isosorbide
| [1] Isosorbide Isosorbide | [1] D00347
D00347
| - | - | [1] 113 113 |
48 |
Isosorbide dinitrate
| [2] Isosorbide Isosorbide; ISOSORBIDE DINITRATE | [1] D00516
D00516
| - | - | [1] 113 113 |
49 |
Ketamine
| [2] Ketamine Ketamine; NMDA | [1] D08098
D08098
| [5] GRIN1 GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 | [20] Alcoholism Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬 | [8] 2 2, 4, 6, 13, 70, 113, 156, 215 |
50 |
L-arginine
| [1] L-arginine L-arginine | [1] D02982
D02982
| - | - | [8] 46 46, 67, 78, 96, 97, 98, 113, 299 |
51 |
L-Glutamine
| [2] Glutamine Glutamine; L-Glutamine | [1] D00015
D00015
| - | - | [8] 87 87, 89, 96, 97, 113, 222, 245, 299 |
52 |
Lisinopril
| [2] Lisinopril Lisinopril; Zestril | [2] D00362
D00362
,
D08131
| [1] ACE ACE 💬 | [6] Chagas disease Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬 | [7] 19 19, 46, 49, 66, 67, 113, 222 |
53 |
Lonafarnib
| [1] Lonafarnib Lonafarnib | [1] D04768
D04768
| [2] FNTA FNTA, FNTB 💬 | [1] Terpenoid backbone biosynthesis Terpenoid backbone biosynthesis 💬 | [2] 113 113, 333 |
54 |
Losartan
| [3] Cozaar Cozaar; Losartan; LOSARTAN POTASSIUM | [1] D08146
D08146
| [1] AGTR1 AGTR1 💬 | [16] AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬 | [17] 17 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
55 |
Losmapimod
| [1] Losmapimod Losmapimod | [1] D09639
D09639
| [4] MAPK11 MAPK11, MAPK12, MAPK13, MAPK14 💬 | [62] AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Alcoholic liver disease, Amyotrophic lateral sclerosis, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Dopaminergic synapse, Endocrine resistance, Epithelial cell signaling in Helicobacter pylori infection, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hepatitis B, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, IL-17 signaling pathway, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Leukocyte transendothelial migration, Lipid and atherosclerosis, MAPK signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Oocyte meiosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Platelet activation, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rap1 signaling pathway, Relaxin signaling pathway, Retrograde endocannabinoid signaling, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thermogenesis, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Yersinia infection 💬 | [2] 113 113, 222 |
56 |
Mannitol
| [4] Aridol Aridol; Bronchitol; Mannite; Mannitol | [1] D00062
D00062
| - | - | [7] 6 6, 13, 28, 60, 96, 113, 299 |
57 |
Metformin
| [5] Metformin Metformin; Metformin HCl; METFORMIN HYDROCHLORIDE; Metformina; Metformine | [1] D04966
D04966
| [2] PRKAA1 PRKAA1, PRKAA2 💬 | [20] AMPK signaling pathway AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬 | [25] 2 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 |
58 |
Methylphenidate
| [3] Methylphenidate Methylphenidate; METHYLPHENIDATE HYDROCHLORIDE; Ritalin | [1] D04999
D04999
| [2] SLC6A2 SLC6A2, SLC6A3 💬 | [7] Alcoholism Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬 | [7] 6 6, 13, 34, 84, 113, 179, 206 |
59 |
Metoprolol
| [2] Metoprolol Metoprolol; METOPROLOL SUCCINATE | [1] D02358
D02358
| [1] ADRB1 ADRB1 💬 | [11] Adrenergic signaling in cardiomyocytes Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬 | [6] 17 17, 57, 58, 113, 193, 226 |
60 |
Mexiletine
| [4] Mexiletina Mexiletina; Mexiletine; Mexitil; Namuscla | [1] D08215
D08215
| [5] SCN1A SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬 | [3] Adrenergic signaling in cardiomyocytes Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬 | [5] 1 1, 2, 10, 113, 114 |
61 |
Modafinil
| [2] Modafinil Modafinil; Provigil | [1] D01832
D01832
| - | - | [5] 6 6, 13, 49, 93, 113 |
62 |
Moxifloxacin
| [2] Moxifloxacin Moxifloxacin; Moxifloxacin Hydrochloride | [1] D08237
D08237
| - | - | [9] 2 2, 6, 46, 49, 85, 86, 113, 240, 299 |
63 |
Nebivolol
| [1] Nebivolol Nebivolol | [1] D05127
D05127
| [1] ADRB1 ADRB1 💬 | [11] Adrenergic signaling in cardiomyocytes Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬 | [4] 17 17, 85, 113, 167 |
64 |
Nitrate
| [1] Nitrate Nitrate | [1] D02313
D02313
| - | - | [4] 58 58, 67, 113, 299 |
65 |
Omigapil
| [1] Omigapil Omigapil | - | - | - | [1] 113 113 |
66 |
Oxatomide
| [1] Oxatomide Oxatomide | [1] D01773
D01773
| [1] ALOX5 ALOX5 💬 | [6] Arachidonic acid metabolism Arachidonic acid metabolism, Fc epsilon RI signaling pathway, Metabolic pathways, Ovarian steroidogenesis, Serotonergic synapse, Toxoplasmosis 💬 | [1] 113 113 |
67 |
Pamrevlumab
| [1] PAMREVLUMAB PAMREVLUMAB | [1] D10969
D10969
| [1] CCN2 CCN2 💬 | [2] Apelin signaling pathway Apelin signaling pathway, Hippo signaling pathway 💬 | [2] 85 85, 113 |
68 |
Pemirolast
| [1] PEMIROLAST PEMIROLAST | [1] D07476
D07476
| - | - | [1] 113 113 |
69 |
Pentoxifylline
| [1] Pentoxifylline Pentoxifylline | [1] D00501
D00501
| - | - | [12] 26 26, 56, 84, 86, 93, 96, 97, 113, 220, 222, 296, 298 |
70 |
Perindopril
| [2] Coversyl Coversyl; Perindopril | [1] D03753
D03753
| [1] ACE ACE 💬 | [6] Chagas disease Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬 | [4] 58 58, 113, 167, 222 |
71 |
Pitolisant
| [1] Pitolisant Pitolisant | [1] D10749
D10749
| [1] HRH3 HRH3 💬 | [1] Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction 💬 | [3] 6 6, 113, 193 |
72 |
Prasterone
| [3] Dehydroepiandrosterone Dehydroepiandrosterone; DHEA; Prasterone | [1] D08409
D08409
| [3] AR AR, ESR1, ESR2 💬 | [12] Breast cancer Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Oocyte meiosis, Pathways in cancer, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬 | [6] 49 49, 53, 83, 86, 96, 113 |
73 |
Prednisolone
| [3] Prednisolona Prednisolona; Prednisolone; Prednisolonum | [1] D00472
D00472
| [1] NR3C1 NR3C1 💬 | [1] Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction 💬 | [42] 3 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 |
74 |
Prednisone
| [3] Prednisona Prednisona; Prednisone; RAYOS | [1] D00473
D00473
| [1] NR3C1 NR3C1 💬 | [1] Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction 💬 | [45] 2 2, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 |
75 |
Ramipril
| [1] Ramipril Ramipril | [1] D00421
D00421
| [1] ACE ACE 💬 | [6] Chagas disease Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬 | [7] 46 46, 49, 66, 67, 113, 218, 257 |
76 |
Ranolazine
| [3] RANEXA RANEXA; Ranolazina; Ranolazine | [1] D05700
D05700
| - | - | [6] 2 2, 58, 86, 96, 113, 114 |
77 |
Resveratrol
| [1] Resveratrol Resveratrol | - | - | - | [6] 2 2, 8, 18, 89, 97, 113 |
78 |
rhIGFBP-3
| [1] RhIGFBP-3 RhIGFBP-3 | - | - | - | [2] 113 113, 195 |
79 |
Rimeporide
| [1] Rimeporide Rimeporide | - | - | - | [1] 113 113 |
80 |
Risedronic acid
| [3] Risedronate Risedronate; RISEDRONATE SODIUM; Risedronic acid | [1] D08484
D08484
| [1] FDPS FDPS 💬 | [4] Human T-cell leukemia virus 1 infection Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬 | [9] 46 46, 50, 66, 93, 95, 96, 107, 113, 274 |
81 |
Salbutamol
| [3] Albuterol Albuterol; Salbutamol; Ventolin | [1] D02147
D02147
| [1] ADRB2 ADRB2 💬 | [9] Adrenergic signaling in cardiomyocytes Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬 | [12] 3 3, 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 |
82 |
Sildenafil
| [6] Mysildecard Mysildecard; Revatio; Sildenafil; SILDENAFIL CITRATE; SILDENAFILO; Viagra | [1] D08514
D08514
| [1] PDE5A PDE5A 💬 | [3] Metabolic pathways Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬 | [17] 6 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 |
83 |
Sodium nitrate
| [1] Sodium Nitrate Sodium Nitrate | - | - | - | [2] 58 58, 113 |
84 |
Somatotropin
| [17] Genotropin Genotropin; Growth hormone; Human growth hormone; Humatrope; Norditropin; Norditropin SimpleXx; NUTROPIN; Nutropin AQ; NutropinAq; OMNITROPE; Recombinant human growth hormone; RhGH; SAIZEN; Somatotropin; Somatropin; SOMATROPINA; Zomacton | - | - | - | [25] 2 2, 3, 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 246, 265, 274, 276, 299, 337 |
85 |
Spironolactone
| [1] Spironolactone Spironolactone | [1] D00443
D00443
| [1] NR3C2 NR3C2 💬 | [1] Aldosterone-regulated sodium reabsorption Aldosterone-regulated sodium reabsorption 💬 | [8] 46 46, 58, 67, 86, 113, 210, 218, 225 |
86 |
SRP-9003
| [1] SRP-9003 SRP-9003 | - | - | - | [1] 113 113 |
87 |
Stamulumab
| [1] MYO-029 MYO-029 | [1] D05917
D05917
| [1] MSTN MSTN 💬 | [1] Cytokine-cytokine receptor interaction Cytokine-cytokine receptor interaction 💬 | [1] 113 113 |
88 |
Tacrolimus
| [2] Prograf Prograf; Tacrolimus | [2] D00107
D00107
,
D08556
| [5] PPP3CA PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 | [33] Alzheimer disease Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬 | [34] 2 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 |
89 |
Tadalafil
| [4] Adcirca Adcirca; Cialis; TADALAFIL; TADALAFILO | [1] D02008
D02008
| [1] PDE5A PDE5A 💬 | [3] Metabolic pathways Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬 | [7] 6 6, 51, 75, 84, 86, 113, 210 |
90 |
Tamoxifen
| [2] TAMOXIFEN TAMOXIFEN; TAMOXIFEN CITRATE | [1] D08559
D08559
| [2] ESR1 ESR1, ESR2 💬 | [10] Breast cancer Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬 | [3] 2 2, 113, 227 |
91 |
Testosterone
| [1] Testosterone Testosterone | [1] D00075
D00075
| [1] AR AR 💬 | [4] Chemical carcinogenesis - receptor activation Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬 | [8] 1 1, 2, 3, 13, 60, 76, 78, 113 |
92 |
Testosterone decanoate
| [1] Testosterone decanoate Testosterone decanoate | [1] D08573
D08573
| [1] AR AR 💬 | [4] Chemical carcinogenesis - receptor activation Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬 | [1] 113 113 |
93 |
Testosterone enanthate
| [1] Testosterone Enanthate Testosterone Enanthate | [1] D00958
D00958
| [1] AR AR 💬 | [4] Chemical carcinogenesis - receptor activation Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬 | [1] 113 113 |
94 |
Testosterone isocaproate
| [1] Testosterone isocaproate Testosterone isocaproate | - | - | - | [1] 113 113 |
95 |
Testosterone phenylpropionate
| [1] Testosterone phenylpropionate Testosterone phenylpropionate | [1] D08574
D08574
| [1] AR AR 💬 | [4] Chemical carcinogenesis - receptor activation Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬 | [1] 113 113 |
96 |
Testosterone propionate
| [1] Testosterone propionate Testosterone propionate | [1] D00959
D00959
| [1] AR AR 💬 | [4] Chemical carcinogenesis - receptor activation Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬 | [1] 113 113 |
97 |
Tetracosactide
| [4] Cosyntropin Cosyntropin; Synacthen Depot; Tetracosactide; Tetracosactrin | [1] D00284
D00284
| [1] MC2R MC2R 💬 | [5] Aldosterone synthesis and secretion Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬 | [5] 78 78, 83, 113, 145, 222 |
98 |
Tideglusib
| [1] Tideglusib Tideglusib | - | - | - | [2] 5 5, 113 |
99 |
Tranilast
| [1] Tranilast Tranilast | [1] D02027
D02027
| - | - | [4] 46 46, 84, 106, 113 |
100 |
Trehalose
| [2] Cabaletta Cabaletta; Trehalose | - | - | - | [4] 2 2, 6, 18, 113 |
101 |
Ubidecarenone
| [3] Coenzyme Q-10 Coenzyme Q-10; Coenzyme Q10; CoQ10 | [1] D01065
D01065
| - | - | [12] 2 2, 5, 6, 8, 10, 18, 46, 57, 86, 113, 214, 215 |
102 |
Vamorolone
| [1] Vamorolone Vamorolone | [1] D11000
D11000
| [1] NR3C1 NR3C1 💬 | [1] Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction 💬 | [2] 97 97, 113 |
103 |
Viltolarsen
| [1] VILTOLARSEN VILTOLARSEN | [1] D11528
D11528
| [1] DMD DMD 💬 | [4] Arrhythmogenic right ventricular cardiomyopathy Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬 | [1] 113 113 |
104 |
Zildistrogene varoparvovec
| [1] RAAV9-CK8-h-µD5 RAAV9-CK8-h-µD5 | - | - | - | [1] 113 113 |
105 |
Zinc
| [3] Nicotinamide Nicotinamide; Wilzin; Zinc | - | - | - | [4] 2 2, 113, 171, 299 |