Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 MAPK14 [23] Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Relaxin signaling pathway, Prion disease, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D09639 Losmapimod [2] 113, 222
2 MAPK14 [23] Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Relaxin signaling pathway, Prion disease, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D10959 Neflamapimod [1] 8
3 F2 [2] Platelet activation, Regulation of actin cytoskeleton D06410 Thrombomodulin Alfa [1] 85
4 F2 [2] Platelet activation, Regulation of actin cytoskeleton D07144 Dabigatran etexilate [2] 51, 75
5 F2 [2] Platelet activation, Regulation of actin cytoskeleton D09707 Dabigatran [5] 51, 75, 85, 91, 124
6 FYN [5] Sphingolipid signaling pathway, Platelet activation, T cell receptor signaling pathway, Prion disease, Viral myocarditis D03658 Dasatinib [2] 51, 85
7 FYN [5] Sphingolipid signaling pathway, Platelet activation, T cell receptor signaling pathway, Prion disease, Viral myocarditis D06414 Dasatinib [2] 51, 85
8 GUCY1A2 [5] Purine metabolism, Vascular smooth muscle contraction, Platelet activation, Renin secretion, Salivary secretion D00517 Amyl Nitrite [1] 58
9 GUCY1A2 [5] Purine metabolism, Vascular smooth muscle contraction, Platelet activation, Renin secretion, Salivary secretion D09572 Riociguat [6] 51, 84, 86, 88, 225, 299
10 GUCY1A1 [5] Purine metabolism, Vascular smooth muscle contraction, Platelet activation, Renin secretion, Salivary secretion D00517 Amyl Nitrite [1] 58
11 GUCY1A1 [5] Purine metabolism, Vascular smooth muscle contraction, Platelet activation, Renin secretion, Salivary secretion D09572 Riociguat [6] 51, 84, 86, 88, 225, 299
12 GUCY1B1 [5] Purine metabolism, Vascular smooth muscle contraction, Platelet activation, Renin secretion, Salivary secretion D00517 Amyl Nitrite [1] 58
13 GUCY1B1 [5] Purine metabolism, Vascular smooth muscle contraction, Platelet activation, Renin secretion, Salivary secretion D09572 Riociguat [6] 51, 84, 86, 88, 225, 299
14 PIK3CA [27] Platinum drug resistance, Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Prion disease, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer D11011 Alpelisib [1] 138
15 PIK3CA [27] Platinum drug resistance, Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Prion disease, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer D11158 Leniolisib [2] 53, 65
16 PIK3CB [27] Platinum drug resistance, Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Prion disease, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer D11158 Leniolisib [2] 53, 65
17 PIK3CD [27] Platinum drug resistance, Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Prion disease, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer D11158 Leniolisib [2] 53, 65
18 PIK3CD [27] Platinum drug resistance, Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Prion disease, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer D11437 Parsaclisib [3] 35, 53, 61
19 MAPK11 [23] Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Relaxin signaling pathway, Prion disease, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D09639 Losmapimod [2] 113, 222
20 MAPK11 [23] Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Relaxin signaling pathway, Prion disease, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D10959 Neflamapimod [1] 8
21 MAPK13 [23] Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Relaxin signaling pathway, Prion disease, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D09639 Losmapimod [2] 113, 222
22 MAPK13 [23] Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Relaxin signaling pathway, Prion disease, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D10959 Neflamapimod [1] 8
23 PTGIR [2] Vascular smooth muscle contraction, Platelet activation D00106 Epoprostenol [1] 86
24 PTGIR [2] Vascular smooth muscle contraction, Platelet activation D01385 Ibudilast [2] 2, 13
25 PTGIR [2] Vascular smooth muscle contraction, Platelet activation D02720 Beraprost [1] 86
26 PTGIR [2] Vascular smooth muscle contraction, Platelet activation D02721 Iloprost [4] 51, 84, 85, 86
27 PTGIR [2] Vascular smooth muscle contraction, Platelet activation D06213 Treprostinil [6] 51, 84, 85, 86, 88, 210
28 PTGIR [2] Vascular smooth muscle contraction, Platelet activation D09994 Selexipag [5] 51, 70, 84, 86, 88
29 PTGIR [2] Vascular smooth muscle contraction, Platelet activation D10725 Ralinepag [1] 86
30 PTGS1 [3] Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes D00109 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251
31 PTGS1 [3] Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes D00118 Naproxen [4] 13, 46, 107, 271
32 PTGS1 [3] Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes D00120 Sulindac [1] 206
33 PTGS1 [3] Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes D00126 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299
34 PTGS1 [3] Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes D00132 Ketoprofen [1] 46
35 PTGS1 [3] Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes D00141 Indomethacin [3] 225, 271, 298
36 PTGS1 [3] Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes D00217 Acetaminophen [15] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337
37 PTGS1 [3] Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes D00330 Flurbiprofen [3] 13, 21, 46
38 PTGS1 [3] Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes D00428 Salsalate [1] 5
39 PTGS1 [3] Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes D01183 Tolfenamic acid [1] 5
40 PTGS1 [3] Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes D01545 Aceclofenac [1] 46
41 PTGS1 [3] Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes D07816 Diclofenac [5] 13, 34, 46, 78, 271
42 PTGS1 [3] Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes D08104 Ketorolac [2] 70, 226
43 PTGS1 [3] Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes D08149 Loxoprofen [2] 46, 271
44 ROCK1 [9] Sphingolipid signaling pathway, Vascular smooth muscle contraction, TGF-beta signaling pathway, Tight junction, Platelet activation, Regulation of actin cytoskeleton, Shigellosis, Yersinia infection, Proteoglycans in cancer D07941 Fasudil [4] 2, 5, 7, 51
45 MAPK12 [23] Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Relaxin signaling pathway, Prion disease, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D09639 Losmapimod [2] 113, 222
46 MAPK12 [23] Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Relaxin signaling pathway, Prion disease, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D10959 Neflamapimod [1] 8
47 P2RY12 [1] Platelet activation D07729 Clopidogrel [3] 49, 51, 86
48 P2RY12 [1] Platelet activation D09017 Ticagrelor [3] 36, 46, 85
49 P2RY12 [1] Platelet activation D10823 Clopidogrel [3] 49, 51, 86
50 P2RY12 [1] Platelet activation D10824 Clopidogrel [3] 49, 51, 86
51 SRC [13] Rap1 signaling pathway, VEGF signaling pathway, Tight junction, Platelet activation, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis, Proteoglycans in cancer D03252 Bosutinib [2] 2, 67
52 SRC [13] Rap1 signaling pathway, VEGF signaling pathway, Tight junction, Platelet activation, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis, Proteoglycans in cancer D03658 Dasatinib [2] 51, 85
53 SRC [13] Rap1 signaling pathway, VEGF signaling pathway, Tight junction, Platelet activation, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis, Proteoglycans in cancer D06414 Dasatinib [2] 51, 85
54 SRC [13] Rap1 signaling pathway, VEGF signaling pathway, Tight junction, Platelet activation, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis, Proteoglycans in cancer D09664 Saracatinib [3] 6, 89, 272
55 SYK [3] Platelet activation, Tuberculosis, Viral carcinogenesis D09347 Fostamatinib [4] 46, 49, 61, 66
56 TBXA2R [1] Platelet activation D01128 Ramatroban [1] 13
57 TBXA2R [1] Platelet activation D01896 Cilostazol [3] 46, 51, 70
58 TBXA2R [1] Platelet activation D04500 Ifetroban [2] 85, 113
59 BTK [2] Platelet activation, Primary immunodeficiency D10223 Ibrutinib [3] 28, 60, 61
60 BTK [2] Platelet activation, Primary immunodeficiency D10893 Acalabrutinib [2] 46, 61
61 BTK [2] Platelet activation, Primary immunodeficiency D11422 Zanubrutinib [5] 13, 63, 222, 300, 331
62 BTK [2] Platelet activation, Primary immunodeficiency D11457 Fenebrutinib [1] 13
63 BTK [2] Platelet activation, Primary immunodeficiency D11478 Branebrutinib [3] 46, 49, 53
64 BTK [2] Platelet activation, Primary immunodeficiency D12160 Orelabrutinib [4] 13, 49, 61, 63
65 BTK [2] Platelet activation, Primary immunodeficiency D12285 Remibrutinib [2] 13, 53
66 BTK [2] Platelet activation, Primary immunodeficiency D12467 Evobrutinib [3] 13, 46, 49
67 VWF [1] Platelet activation D11160 Caplacizumab [1] 64
68 ROCK2 [10] Sphingolipid signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway, Tight junction, Platelet activation, Regulation of actin cytoskeleton, Shigellosis, Salmonella infection, Yersinia infection, Proteoglycans in cancer D07941 Fasudil [4] 2, 5, 7, 51
69 ROCK2 [10] Sphingolipid signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway, Tight junction, Platelet activation, Regulation of actin cytoskeleton, Shigellosis, Salmonella infection, Yersinia infection, Proteoglycans in cancer D11815 Belumosudil [2] 51, 85