Target Gene/Pathway PATHWAY / GENE


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No. KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG DRUG DrugBank 指定難病告示番号
1 PARP2 2件: Base excision repair 💬, Apoptosis 💬 D09730 Olaparib 2件: 86, 285
2 PDE10A 4件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Morphine addiction 💬 D00227 Aminophylline 1件: 63
3 PDE10A 4件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Morphine addiction 💬 D00371 Theophylline 2件: 236, 299
4 PDE10A 4件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Morphine addiction 💬 D00718 Flavoxate 1件: 226
5 PDE10A 4件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Morphine addiction 💬 D01712 Theophylline 2件: 236, 299
6 PDE10A 4件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Morphine addiction 💬 D02017 Theophylline 2件: 236, 299
7 PDE10A 4件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Morphine addiction 💬 D05429 Aminophylline 1件: 63
8 PDE10A 4件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Morphine addiction 💬 D06103 Theophylline 2件: 236, 299
9 PDE10A 4件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Morphine addiction 💬 D06104 Theophylline 2件: 236, 299
10 PDE10A 4件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Morphine addiction 💬 D07546 Bucladesine 1件: 246
11 PDE10A 4件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Morphine addiction 💬 D07961 Flavoxate 1件: 226
12 PARP1 5件: Base excision repair 💬, NF-kappa B signaling pathway 💬, Apoptosis 💬, Necroptosis 💬, Diabetic cardiomyopathy 💬 D09730 Olaparib 2件: 86, 285
13 POLA2 1件: DNA replication 💬 D03546 Clofarabine 9件: 19, 20, 40, 46, 49, 60, 96, 234, 326
14 PCSK9 1件: Cholesterol metabolism 💬 D10335 Alirocumab 1件: 79
15 PCSK9 1件: Cholesterol metabolism 💬 D10557 Evolocumab 2件: 79, 222
16 PCSK9 1件: Cholesterol metabolism 💬 D11931 Inclisiran 1件: 79
17 PDE7B 3件: Purine metabolism 💬, Metabolic pathways 💬, Morphine addiction 💬 D00227 Aminophylline 1件: 63
18 PDE7B 3件: Purine metabolism 💬, Metabolic pathways 💬, Morphine addiction 💬 D00371 Theophylline 2件: 236, 299
19 PDE7B 3件: Purine metabolism 💬, Metabolic pathways 💬, Morphine addiction 💬 D00718 Flavoxate 1件: 226
20 PDE7B 3件: Purine metabolism 💬, Metabolic pathways 💬, Morphine addiction 💬 D01712 Theophylline 2件: 236, 299
21 PDE7B 3件: Purine metabolism 💬, Metabolic pathways 💬, Morphine addiction 💬 D02017 Theophylline 2件: 236, 299
22 PDE7B 3件: Purine metabolism 💬, Metabolic pathways 💬, Morphine addiction 💬 D05429 Aminophylline 1件: 63
23 PDE7B 3件: Purine metabolism 💬, Metabolic pathways 💬, Morphine addiction 💬 D06103 Theophylline 2件: 236, 299
24 PDE7B 3件: Purine metabolism 💬, Metabolic pathways 💬, Morphine addiction 💬 D06104 Theophylline 2件: 236, 299
25 PDE7B 3件: Purine metabolism 💬, Metabolic pathways 💬, Morphine addiction 💬 D07546 Bucladesine 1件: 246
26 PDE7B 3件: Purine metabolism 💬, Metabolic pathways 💬, Morphine addiction 💬 D07961 Flavoxate 1件: 226
27 P2RX3 3件: Calcium signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Taste transduction 💬 D11349 Gefapixant 2件: 85, 226
28 PAH 5件: Phenylalanine metabolism 💬, Phenylalanine, tyrosine and tryptophan biosynthesis 💬, Folate biosynthesis 💬, Metabolic pathways 💬, Biosynthesis of amino acids 💬 D11077 Pegvaliase 1件: 240
29 PDE11A 4件: Purine metabolism 💬, Metabolic pathways 💬, Cushing syndrome 💬, Morphine addiction 💬 D00227 Aminophylline 1件: 63
30 PDE11A 4件: Purine metabolism 💬, Metabolic pathways 💬, Cushing syndrome 💬, Morphine addiction 💬 D00371 Theophylline 2件: 236, 299
31 PDE11A 4件: Purine metabolism 💬, Metabolic pathways 💬, Cushing syndrome 💬, Morphine addiction 💬 D00718 Flavoxate 1件: 226
32 PDE11A 4件: Purine metabolism 💬, Metabolic pathways 💬, Cushing syndrome 💬, Morphine addiction 💬 D01712 Theophylline 2件: 236, 299
33 PDE11A 4件: Purine metabolism 💬, Metabolic pathways 💬, Cushing syndrome 💬, Morphine addiction 💬 D02017 Theophylline 2件: 236, 299
34 PDE11A 4件: Purine metabolism 💬, Metabolic pathways 💬, Cushing syndrome 💬, Morphine addiction 💬 D05429 Aminophylline 1件: 63
35 PDE11A 4件: Purine metabolism 💬, Metabolic pathways 💬, Cushing syndrome 💬, Morphine addiction 💬 D06103 Theophylline 2件: 236, 299
36 PDE11A 4件: Purine metabolism 💬, Metabolic pathways 💬, Cushing syndrome 💬, Morphine addiction 💬 D06104 Theophylline 2件: 236, 299
37 PDE11A 4件: Purine metabolism 💬, Metabolic pathways 💬, Cushing syndrome 💬, Morphine addiction 💬 D07546 Bucladesine 1件: 246
38 PDE11A 4件: Purine metabolism 💬, Metabolic pathways 💬, Cushing syndrome 💬, Morphine addiction 💬 D07961 Flavoxate 1件: 226
39 PDCD1 3件: Cell adhesion molecules 💬, T cell receptor signaling pathway 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 D10316 Nivolumab 12件: 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159
40 PDCD1 3件: Cell adhesion molecules 💬, T cell receptor signaling pathway 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 D10574 Pembrolizumab 2件: 25, 285
41 PDE1A 7件: Purine metabolism 💬, Metabolic pathways 💬, Calcium signaling pathway 💬, Olfactory transduction 💬, Taste transduction 💬, Renin secretion 💬, Morphine addiction 💬 D00227 Aminophylline 1件: 63
42 PDE1A 7件: Purine metabolism 💬, Metabolic pathways 💬, Calcium signaling pathway 💬, Olfactory transduction 💬, Taste transduction 💬, Renin secretion 💬, Morphine addiction 💬 D00371 Theophylline 2件: 236, 299
43 PDE1A 7件: Purine metabolism 💬, Metabolic pathways 💬, Calcium signaling pathway 💬, Olfactory transduction 💬, Taste transduction 💬, Renin secretion 💬, Morphine addiction 💬 D00718 Flavoxate 1件: 226
44 PDE1A 7件: Purine metabolism 💬, Metabolic pathways 💬, Calcium signaling pathway 💬, Olfactory transduction 💬, Taste transduction 💬, Renin secretion 💬, Morphine addiction 💬 D01712 Theophylline 2件: 236, 299
45 PDE1A 7件: Purine metabolism 💬, Metabolic pathways 💬, Calcium signaling pathway 💬, Olfactory transduction 💬, Taste transduction 💬, Renin secretion 💬, Morphine addiction 💬 D02017 Theophylline 2件: 236, 299
46 PDE1A 7件: Purine metabolism 💬, Metabolic pathways 💬, Calcium signaling pathway 💬, Olfactory transduction 💬, Taste transduction 💬, Renin secretion 💬, Morphine addiction 💬 D05429 Aminophylline 1件: 63
47 PDE1A 7件: Purine metabolism 💬, Metabolic pathways 💬, Calcium signaling pathway 💬, Olfactory transduction 💬, Taste transduction 💬, Renin secretion 💬, Morphine addiction 💬 D06103 Theophylline 2件: 236, 299
48 PDE1A 7件: Purine metabolism 💬, Metabolic pathways 💬, Calcium signaling pathway 💬, Olfactory transduction 💬, Taste transduction 💬, Renin secretion 💬, Morphine addiction 💬 D06104 Theophylline 2件: 236, 299
49 PDE1A 7件: Purine metabolism 💬, Metabolic pathways 💬, Calcium signaling pathway 💬, Olfactory transduction 💬, Taste transduction 💬, Renin secretion 💬, Morphine addiction 💬 D07546 Bucladesine 1件: 246
50 PDE1A 7件: Purine metabolism 💬, Metabolic pathways 💬, Calcium signaling pathway 💬, Olfactory transduction 💬, Taste transduction 💬, Renin secretion 💬, Morphine addiction 💬 D07961 Flavoxate 1件: 226
51 PDE1C 7件: Purine metabolism 💬, Metabolic pathways 💬, Calcium signaling pathway 💬, Olfactory transduction 💬, Taste transduction 💬, Renin secretion 💬, Morphine addiction 💬 D00227 Aminophylline 1件: 63
52 PDE1C 7件: Purine metabolism 💬, Metabolic pathways 💬, Calcium signaling pathway 💬, Olfactory transduction 💬, Taste transduction 💬, Renin secretion 💬, Morphine addiction 💬 D00371 Theophylline 2件: 236, 299
53 PDE1C 7件: Purine metabolism 💬, Metabolic pathways 💬, Calcium signaling pathway 💬, Olfactory transduction 💬, Taste transduction 💬, Renin secretion 💬, Morphine addiction 💬 D00718 Flavoxate 1件: 226
54 PDE1C 7件: Purine metabolism 💬, Metabolic pathways 💬, Calcium signaling pathway 💬, Olfactory transduction 💬, Taste transduction 💬, Renin secretion 💬, Morphine addiction 💬 D01712 Theophylline 2件: 236, 299
55 PDE1C 7件: Purine metabolism 💬, Metabolic pathways 💬, Calcium signaling pathway 💬, Olfactory transduction 💬, Taste transduction 💬, Renin secretion 💬, Morphine addiction 💬 D02017 Theophylline 2件: 236, 299
56 PDE1C 7件: Purine metabolism 💬, Metabolic pathways 💬, Calcium signaling pathway 💬, Olfactory transduction 💬, Taste transduction 💬, Renin secretion 💬, Morphine addiction 💬 D05429 Aminophylline 1件: 63
57 PDE1C 7件: Purine metabolism 💬, Metabolic pathways 💬, Calcium signaling pathway 💬, Olfactory transduction 💬, Taste transduction 💬, Renin secretion 💬, Morphine addiction 💬 D06103 Theophylline 2件: 236, 299
58 PDE1C 7件: Purine metabolism 💬, Metabolic pathways 💬, Calcium signaling pathway 💬, Olfactory transduction 💬, Taste transduction 💬, Renin secretion 💬, Morphine addiction 💬 D06104 Theophylline 2件: 236, 299
59 PDE1C 7件: Purine metabolism 💬, Metabolic pathways 💬, Calcium signaling pathway 💬, Olfactory transduction 💬, Taste transduction 💬, Renin secretion 💬, Morphine addiction 💬 D07546 Bucladesine 1件: 246
60 PDE1C 7件: Purine metabolism 💬, Metabolic pathways 💬, Calcium signaling pathway 💬, Olfactory transduction 💬, Taste transduction 💬, Renin secretion 💬, Morphine addiction 💬 D07961 Flavoxate 1件: 226
61 PDE2A 6件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, Olfactory transduction 💬, Aldosterone synthesis and secretion 💬, Morphine addiction 💬 D00227 Aminophylline 1件: 63
62 PDE2A 6件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, Olfactory transduction 💬, Aldosterone synthesis and secretion 💬, Morphine addiction 💬 D00371 Theophylline 2件: 236, 299
63 PDE2A 6件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, Olfactory transduction 💬, Aldosterone synthesis and secretion 💬, Morphine addiction 💬 D00528 Caffeine 9件: 2, 6, 13, 21, 46, 78, 96, 97, 265
64 PDE2A 6件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, Olfactory transduction 💬, Aldosterone synthesis and secretion 💬, Morphine addiction 💬 D00718 Flavoxate 1件: 226
65 PDE2A 6件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, Olfactory transduction 💬, Aldosterone synthesis and secretion 💬, Morphine addiction 💬 D01453 Caffeine 9件: 2, 6, 13, 21, 46, 78, 96, 97, 265
66 PDE2A 6件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, Olfactory transduction 💬, Aldosterone synthesis and secretion 💬, Morphine addiction 💬 D01712 Theophylline 2件: 236, 299
67 PDE2A 6件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, Olfactory transduction 💬, Aldosterone synthesis and secretion 💬, Morphine addiction 💬 D02017 Theophylline 2件: 236, 299
68 PDE2A 6件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, Olfactory transduction 💬, Aldosterone synthesis and secretion 💬, Morphine addiction 💬 D05429 Aminophylline 1件: 63
69 PDE2A 6件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, Olfactory transduction 💬, Aldosterone synthesis and secretion 💬, Morphine addiction 💬 D06103 Theophylline 2件: 236, 299
70 PDE2A 6件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, Olfactory transduction 💬, Aldosterone synthesis and secretion 💬, Morphine addiction 💬 D06104 Theophylline 2件: 236, 299
71 PDE2A 6件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, Olfactory transduction 💬, Aldosterone synthesis and secretion 💬, Morphine addiction 💬 D07546 Bucladesine 1件: 246
72 PDE2A 6件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, Olfactory transduction 💬, Aldosterone synthesis and secretion 💬, Morphine addiction 💬 D07961 Flavoxate 1件: 226
73 PDE3A 6件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Renin secretion 💬, Morphine addiction 💬 D00227 Aminophylline 1件: 63
74 PDE3A 6件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Renin secretion 💬, Morphine addiction 💬 D00371 Theophylline 2件: 236, 299
75 PDE3A 6件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Renin secretion 💬, Morphine addiction 💬 D00417 Milrinone 1件: 294
76 PDE3A 6件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Renin secretion 💬, Morphine addiction 💬 D00528 Caffeine 9件: 2, 6, 13, 21, 46, 78, 96, 97, 265
77 PDE3A 6件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Renin secretion 💬, Morphine addiction 💬 D00718 Flavoxate 1件: 226
78 PDE3A 6件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Renin secretion 💬, Morphine addiction 💬 D01385 Ibudilast 2件: 2, 13
79 PDE3A 6件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Renin secretion 💬, Morphine addiction 💬 D01453 Caffeine 9件: 2, 6, 13, 21, 46, 78, 96, 97, 265
80 PDE3A 6件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Renin secretion 💬, Morphine addiction 💬 D01712 Theophylline 2件: 236, 299
81 PDE3A 6件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Renin secretion 💬, Morphine addiction 💬 D01896 Cilostazol 3件: 51, 70, 124
82 PDE3A 6件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Renin secretion 💬, Morphine addiction 💬 D02017 Theophylline 2件: 236, 299
83 PDE3A 6件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Renin secretion 💬, Morphine addiction 💬 D02085 Milrinone 1件: 294
84 PDE3A 6件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Renin secretion 💬, Morphine addiction 💬 D04720 Levosimendan 1件: 2
85 PDE3A 6件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Renin secretion 💬, Morphine addiction 💬 D05429 Aminophylline 1件: 63
86 PDE3A 6件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Renin secretion 💬, Morphine addiction 💬 D06103 Theophylline 2件: 236, 299
87 PDE3A 6件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Renin secretion 💬, Morphine addiction 💬 D06104 Theophylline 2件: 236, 299
88 PDE3A 6件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Renin secretion 💬, Morphine addiction 💬 D07546 Bucladesine 1件: 246
89 PDE3A 6件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Renin secretion 💬, Morphine addiction 💬 D07961 Flavoxate 1件: 226
90 PDE3B 11件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Apelin signaling pathway 💬, Insulin signaling pathway 💬, Progesterone-mediated oocyte maturation 💬, Glucagon signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Morphine addiction 💬 D00227 Aminophylline 1件: 63
91 PDE3B 11件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Apelin signaling pathway 💬, Insulin signaling pathway 💬, Progesterone-mediated oocyte maturation 💬, Glucagon signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Morphine addiction 💬 D00371 Theophylline 2件: 236, 299
92 PDE3B 11件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Apelin signaling pathway 💬, Insulin signaling pathway 💬, Progesterone-mediated oocyte maturation 💬, Glucagon signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Morphine addiction 💬 D00417 Milrinone 1件: 294
93 PDE3B 11件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Apelin signaling pathway 💬, Insulin signaling pathway 💬, Progesterone-mediated oocyte maturation 💬, Glucagon signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Morphine addiction 💬 D00528 Caffeine 9件: 2, 6, 13, 21, 46, 78, 96, 97, 265
94 PDE3B 11件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Apelin signaling pathway 💬, Insulin signaling pathway 💬, Progesterone-mediated oocyte maturation 💬, Glucagon signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Morphine addiction 💬 D00718 Flavoxate 1件: 226
95 PDE3B 11件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Apelin signaling pathway 💬, Insulin signaling pathway 💬, Progesterone-mediated oocyte maturation 💬, Glucagon signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Morphine addiction 💬 D01385 Ibudilast 2件: 2, 13
96 PDE3B 11件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Apelin signaling pathway 💬, Insulin signaling pathway 💬, Progesterone-mediated oocyte maturation 💬, Glucagon signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Morphine addiction 💬 D01453 Caffeine 9件: 2, 6, 13, 21, 46, 78, 96, 97, 265
97 PDE3B 11件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Apelin signaling pathway 💬, Insulin signaling pathway 💬, Progesterone-mediated oocyte maturation 💬, Glucagon signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Morphine addiction 💬 D01712 Theophylline 2件: 236, 299
98 PDE3B 11件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Apelin signaling pathway 💬, Insulin signaling pathway 💬, Progesterone-mediated oocyte maturation 💬, Glucagon signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Morphine addiction 💬 D01896 Cilostazol 3件: 51, 70, 124
99 PDE3B 11件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Apelin signaling pathway 💬, Insulin signaling pathway 💬, Progesterone-mediated oocyte maturation 💬, Glucagon signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Morphine addiction 💬 D02017 Theophylline 2件: 236, 299
100 PDE3B 11件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Apelin signaling pathway 💬, Insulin signaling pathway 💬, Progesterone-mediated oocyte maturation 💬, Glucagon signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Morphine addiction 💬 D02085 Milrinone 1件: 294
101 PDE3B 11件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Apelin signaling pathway 💬, Insulin signaling pathway 💬, Progesterone-mediated oocyte maturation 💬, Glucagon signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Morphine addiction 💬 D04720 Levosimendan 1件: 2
102 PDE3B 11件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Apelin signaling pathway 💬, Insulin signaling pathway 💬, Progesterone-mediated oocyte maturation 💬, Glucagon signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Morphine addiction 💬 D05429 Aminophylline 1件: 63
103 PDE3B 11件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Apelin signaling pathway 💬, Insulin signaling pathway 💬, Progesterone-mediated oocyte maturation 💬, Glucagon signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Morphine addiction 💬 D06103 Theophylline 2件: 236, 299
104 PDE3B 11件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Apelin signaling pathway 💬, Insulin signaling pathway 💬, Progesterone-mediated oocyte maturation 💬, Glucagon signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Morphine addiction 💬 D06104 Theophylline 2件: 236, 299
105 PDE3B 11件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Apelin signaling pathway 💬, Insulin signaling pathway 💬, Progesterone-mediated oocyte maturation 💬, Glucagon signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Morphine addiction 💬 D07546 Bucladesine 1件: 246
106 PDE3B 11件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Apelin signaling pathway 💬, Insulin signaling pathway 💬, Progesterone-mediated oocyte maturation 💬, Glucagon signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Morphine addiction 💬 D07961 Flavoxate 1件: 226
107 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D00227 Aminophylline 1件: 63
108 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D00302 Dipyridamole 6件: 46, 49, 51, 66, 96, 224
109 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D00371 Theophylline 2件: 236, 299
110 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D00528 Caffeine 9件: 2, 6, 13, 21, 46, 78, 96, 97, 265
111 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D00718 Flavoxate 1件: 226
112 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D01385 Ibudilast 2件: 2, 13
113 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D01453 Caffeine 9件: 2, 6, 13, 21, 46, 78, 96, 97, 265
114 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D01712 Theophylline 2件: 236, 299
115 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D01783 Rolipram 2件: 8, 13
116 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D02017 Theophylline 2件: 236, 299
117 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D05429 Aminophylline 1件: 63
118 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D05744 Roflumilast 2件: 84, 299
119 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D06103 Theophylline 2件: 236, 299
120 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D06104 Theophylline 2件: 236, 299
121 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D07546 Bucladesine 1件: 246
122 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D07961 Flavoxate 1件: 226
123 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D08860 Apremilast 7件: 46, 50, 56, 97, 107, 162, 271
124 PDE4B 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D00227 Aminophylline 1件: 63
125 PDE4B 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D00371 Theophylline 2件: 236, 299
126 PDE4B 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D00528 Caffeine 9件: 2, 6, 13, 21, 46, 78, 96, 97, 265
127 PDE4B 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D00718 Flavoxate 1件: 226
128 PDE4B 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D01385 Ibudilast 2件: 2, 13
129 PDE4B 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D01453 Caffeine 9件: 2, 6, 13, 21, 46, 78, 96, 97, 265
130 PDE4B 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D01712 Theophylline 2件: 236, 299
131 PDE4B 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D01783 Rolipram 2件: 8, 13
132 PDE4B 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D02017 Theophylline 2件: 236, 299
133 PDE4B 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D05429 Aminophylline 1件: 63
134 PDE4B 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D05744 Roflumilast 2件: 84, 299
135 PDE4B 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D06103 Theophylline 2件: 236, 299
136 PDE4B 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D06104 Theophylline 2件: 236, 299
137 PDE4B 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D07546 Bucladesine 1件: 246
138 PDE4B 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D07961 Flavoxate 1件: 226
139 PDE4B 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D08860 Apremilast 7件: 46, 50, 56, 97, 107, 162, 271
140 PDE4C 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D00227 Aminophylline 1件: 63
141 PDE4C 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D00371 Theophylline 2件: 236, 299
142 PDE4C 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D00528 Caffeine 9件: 2, 6, 13, 21, 46, 78, 96, 97, 265
143 PDE4C 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D00718 Flavoxate 1件: 226
144 PDE4C 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D01385 Ibudilast 2件: 2, 13
145 PDE4C 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D01453 Caffeine 9件: 2, 6, 13, 21, 46, 78, 96, 97, 265
146 PDE4C 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D01712 Theophylline 2件: 236, 299
147 PDE4C 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D01783 Rolipram 2件: 8, 13
148 PDE4C 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬