Target Gene/Pathway PATHWAY / GENE


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No. KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG DRUG DrugBank 指定難病告示番号
1 LCK 10件: NF-kappa B signaling pathway 💬, Osteoclast differentiation 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, Yersinia infection 💬, Human T-cell leukemia virus 1 infection 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Primary immunodeficiency 💬 D03658 Dasatinib 2件: 51, 85
2 LCK 10件: NF-kappa B signaling pathway 💬, Osteoclast differentiation 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, Yersinia infection 💬, Human T-cell leukemia virus 1 infection 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Primary immunodeficiency 💬 D06414 Dasatinib 2件: 51, 85
3 LEPR 6件: Cytokine-cytokine receptor interaction 💬, Neuroactive ligand-receptor interaction 💬, AMPK signaling pathway 💬, JAK-STAT signaling pathway 💬, Adipocytokine signaling pathway 💬, Non-alcoholic fatty liver disease 💬 D05014 Metreleptin 1件: 265
4 LIPA 3件: Steroid biosynthesis 💬, Lysosome 💬, Cholesterol metabolism 💬 D10377 Sebelipase alfa 1件: 19
5 LTA 7件: Cytokine-cytokine receptor interaction 💬, Viral protein interaction with cytokine and cytokine receptor 💬, NF-kappa B signaling pathway 💬, TNF signaling pathway 💬, Type I diabetes mellitus 💬, Human T-cell leukemia virus 1 infection 💬, Herpes simplex virus 1 infection 💬 D00742 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298
6 LTA 7件: Cytokine-cytokine receptor interaction 💬, Viral protein interaction with cytokine and cytokine receptor 💬, NF-kappa B signaling pathway 💬, TNF signaling pathway 💬, Type I diabetes mellitus 💬, Human T-cell leukemia virus 1 infection 💬, Herpes simplex virus 1 infection 💬 D10187 Pateclizumab 1件: 46
7 LTB 3件: Cytokine-cytokine receptor interaction 💬, NF-kappa B signaling pathway 💬, Rheumatoid arthritis 💬 D08866 Baminercept 4件: 13, 46, 53, 97