Target Gene/Pathway Pathway / Gene


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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 COMT 💬 4件: Steroid hormone biosynthesis, Tyrosine metabolism, Metabolic pathways, Dopaminergic synapse Entacapone 💬 Entacapone 2件: 6, 17 💬
2 COMT 💬 4件: Steroid hormone biosynthesis, Tyrosine metabolism, Metabolic pathways, Dopaminergic synapse Tolcapone 💬 Tolcapone 3件: 6, 28, 127 💬
3 COMT 💬 4件: Steroid hormone biosynthesis, Tyrosine metabolism, Metabolic pathways, Dopaminergic synapse Opicapone 💬 Opicapone 1件: 6 💬
4 CYP11A1 💬 6件: Steroid hormone biosynthesis, Metabolic pathways, Ovarian steroidogenesis, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome Levoketoconazole 💬 Levoketoconazole 1件: 75 💬
5 CYP11B1 💬 4件: Steroid hormone biosynthesis, Metabolic pathways, Cortisol synthesis and secretion, Cushing syndrome Metyrapone 💬 Metyrapone 1件: 75 💬
6 CYP11B1 💬 4件: Steroid hormone biosynthesis, Metabolic pathways, Cortisol synthesis and secretion, Cushing syndrome Levoketoconazole 💬 Levoketoconazole 1件: 75 💬
7 CYP11B2 💬 3件: Steroid hormone biosynthesis, Metabolic pathways, Aldosterone synthesis and secretion Osilodrostat 💬 Osilodrostat 1件: 75 💬
8 CYP17A1 💬 6件: Steroid hormone biosynthesis, Metabolic pathways, Ovarian steroidogenesis, Prolactin signaling pathway, Cortisol synthesis and secretion, Cushing syndrome Ketoconazole 💬 Ketoconazole 3件: 8, 13, 75 💬
9 CYP17A1 💬 6件: Steroid hormone biosynthesis, Metabolic pathways, Ovarian steroidogenesis, Prolactin signaling pathway, Cortisol synthesis and secretion, Cushing syndrome Levoketoconazole 💬 Levoketoconazole 1件: 75 💬
10 CYP19A1 💬 3件: Steroid hormone biosynthesis, Metabolic pathways, Ovarian steroidogenesis Anastrozole 💬 Anastrozole 3件: 78, 86, 193 💬
11 CYP19A1 💬 3件: Steroid hormone biosynthesis, Metabolic pathways, Ovarian steroidogenesis Letrozole 💬 Letrozole 2件: 81, 89 💬
12 SRD5A1 💬 2件: Steroid hormone biosynthesis, Metabolic pathways Dutasteride 💬 Dutasteride 2件: 1, 2 💬
13 SRD5A2 💬 3件: Steroid hormone biosynthesis, Metabolic pathways, Prostate cancer Finasteride 💬 Finasteride 1件: 6 💬
14 SRD5A2 💬 3件: Steroid hormone biosynthesis, Metabolic pathways, Prostate cancer Dutasteride 💬 Dutasteride 2件: 1, 2 💬