Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Adherens junction 💬
1件: IGF1R 💬 D03297 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
2 Adherens junction 💬
1件: IGF1R 💬 D04870 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
3 Alcoholism 💬
1件: ADORA2A 💬 D00528 💬 Caffeine 9件:  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
4 Alcoholism 💬
1件: ADORA2A 💬 D01453 💬 Caffeine 9件:  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
5 Alcoholism 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00848 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
6 Alcoholism 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
7 Alcoholism 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03744 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
8 Aldosterone synthesis and secretion 💬
1件: MC2R 💬 D00146 💬 Corticotropin 15件:  2 , 13, 14, 46, 49, 50, 66, 75, 78, 81, 84, 145, 193, 205, 222 💬
9 Aldosterone synthesis and secretion 💬
1件: MC2R 💬 D00284 💬 Tetracosactide 5件: 78, 83, 113, 145, 222 💬
10 Aldosterone synthesis and secretion 💬
1件: PDE2A 💬 D00528 💬 Caffeine 9件:  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
11 Aldosterone synthesis and secretion 💬
1件: PDE2A 💬 D01453 💬 Caffeine 9件:  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
12 Alzheimer disease 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00848 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
13 Alzheimer disease 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
14 Alzheimer disease 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03744 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
15 Alzheimer disease 💬
1件: PTGS2 💬 D00903 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
16 Alzheimer disease 💬
1件: PTGS2 💬 D00904 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
17 Alzheimer disease 💬
1件: PTGS2 💬 D07816 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
18 Amphetamine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00848 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
19 Amphetamine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
20 Amphetamine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03744 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
21 AMPK signaling pathway 💬
1件: IGF1R 💬 D03297 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
22 AMPK signaling pathway 💬
1件: IGF1R 💬 D04870 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
23 AMPK signaling pathway 💬
1件: PPARG 💬 D00945 💬 Pioglitazone 17件:  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
24 AMPK signaling pathway 💬
1件: PPARG 💬 D08378 💬 Pioglitazone 17件:  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
25 Amyotrophic lateral sclerosis 💬
6件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬 D00848 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
26 Amyotrophic lateral sclerosis 💬
6件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬 D03742 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
27 Amyotrophic lateral sclerosis 💬
6件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬 D03744 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
28 Apelin signaling pathway 💬
1件: PDE3B 💬 D00528 💬 Caffeine 9件:  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
29 Apelin signaling pathway 💬
1件: PDE3B 💬 D01453 💬 Caffeine 9件:  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
30 Arachidonic acid metabolism 💬
2件: PTGS1, PTGS2 💬 D00903 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
31 Arachidonic acid metabolism 💬
2件: PTGS1, PTGS2 💬 D00904 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
32 Arachidonic acid metabolism 💬
2件: PTGS1, PTGS2 💬 D07816 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
33 Autophagy - animal 💬
1件: IGF1R 💬 D03297 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
34 Autophagy - animal 💬
1件: IGF1R 💬 D04870 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
35 Breast cancer 💬
1件: IGF1R 💬 D03297 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
36 Breast cancer 💬
1件: IGF1R 💬 D04870 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
37 C-type lectin receptor signaling pathway 💬
1件: PTGS2 💬 D00903 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
38 C-type lectin receptor signaling pathway 💬
1件: PTGS2 💬 D00904 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
39 C-type lectin receptor signaling pathway 💬
1件: PTGS2 💬 D07816 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
40 Calcium signaling pathway 💬
2件: ADORA2A, PDE1B 💬 D00528 💬 Caffeine 9件:  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
41 Calcium signaling pathway 💬
2件: ADORA2A, PDE1B 💬 D01453 💬 Caffeine 9件:  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
42 Calcium signaling pathway 💬
4件: GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 D00848 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
43 Calcium signaling pathway 💬
4件: GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
44 Calcium signaling pathway 💬
4件: GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 D03744 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
45 cAMP signaling pathway 💬
8件: ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 D00528 💬 Caffeine 9件:  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
46 cAMP signaling pathway 💬
8件: ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 D01453 💬 Caffeine 9件:  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
47 cAMP signaling pathway 💬
1件: GHSR 💬 D10563 💬 Macimorelin 1件: 78 💬
48 cAMP signaling pathway 💬
1件: GLP1R 💬 D04121 💬 Exenatide 6件:  6 , 17, 72, 78, 193, 233 💬
49 cAMP signaling pathway 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00848 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
50 cAMP signaling pathway 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
51 cAMP signaling pathway 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03744 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
52 cAMP signaling pathway 💬
1件: MC2R 💬 D00146 💬 Corticotropin 15件:  2 , 13, 14, 46, 49, 50, 66, 75, 78, 81, 84, 145, 193, 205, 222 💬
53 cAMP signaling pathway 💬
1件: MC2R 💬 D00284 💬 Tetracosactide 5件: 78, 83, 113, 145, 222 💬
54 cAMP signaling pathway 💬
3件: SSTR1, SSTR2, SSTR5 💬 D07431 💬 Somatostatin 2件: 67, 78 💬
55 cGMP-PKG signaling pathway 💬
5件: ADORA1, PDE2A, PDE3A, PDE3B, PDE5A 💬 D00528 💬 Caffeine 9件:  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
56 cGMP-PKG signaling pathway 💬
5件: ADORA1, PDE2A, PDE3A, PDE3B, PDE5A 💬 D01453 💬 Caffeine 9件:  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
57 cGMP-PKG signaling pathway 💬
3件: ADRA2A, ADRA2B, ADRA2C 💬 D00281 💬 Clonidine 4件:  6 , 65, 70, 78 💬
58 cGMP-PKG signaling pathway 💬
3件: ADRA2A, ADRA2B, ADRA2C 💬 D00604 💬 Clonidine 4件:  6 , 65, 70, 78 💬
59 Chemical carcinogenesis - DNA adducts 💬
1件: PTGS2 💬 D00903 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
60 Chemical carcinogenesis - DNA adducts 💬
1件: PTGS2 💬 D00904 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
61 Chemical carcinogenesis - DNA adducts 💬
1件: PTGS2 💬 D07816 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
62 Chemical carcinogenesis - receptor activation 💬
1件: AR 💬 D00075 💬 Testosterone 9件:  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
63 Chemical carcinogenesis - receptor activation 💬
1件: AR 💬 D00957 💬 Testosterone 9件:  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
64 Chemical carcinogenesis - receptor activation 💬
1件: AR 💬 D00958 💬 Testosterone 9件:  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
65 Chemical carcinogenesis - receptor activation 💬
1件: AR 💬 D00959 💬 Testosterone 9件:  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
66 Chemical carcinogenesis - receptor activation 💬
1件: AR 💬 D06085 💬 Testosterone 9件:  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
67 Chemical carcinogenesis - receptor activation 💬
1件: AR 💬 D06087 💬 Testosterone 9件:  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
68 Cholinergic synapse 💬
1件: ACHE 💬 D00670 💬 Donepezil 9件:  5 ,  6 , 13, 46, 78, 124, 127, 156, 206 💬
69 Cholinergic synapse 💬
1件: ACHE 💬 D07869 💬 Donepezil 9件:  5 ,  6 , 13, 46, 78, 124, 127, 156, 206 💬
70 Circadian entrainment 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00848 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
71 Circadian entrainment 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
72 Circadian entrainment 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03744 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
73 Cocaine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00848 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
74 Cocaine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
75 Cocaine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03744 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
76 Cortisol synthesis and secretion 💬
1件: MC2R 💬 D00146 💬 Corticotropin 15件:  2 , 13, 14, 46, 49, 50, 66, 75, 78, 81, 84, 145, 193, 205, 222 💬
77 Cortisol synthesis and secretion 💬
1件: MC2R 💬 D00284 💬 Tetracosactide 5件: 78, 83, 113, 145, 222 💬
78 Cushing syndrome 💬
1件: MC2R 💬 D00146 💬 Corticotropin 15件:  2 , 13, 14, 46, 49, 50, 66, 75, 78, 81, 84, 145, 193, 205, 222 💬
79 Cushing syndrome 💬
1件: MC2R 💬 D00284 💬 Tetracosactide 5件: 78, 83, 113, 145, 222 💬
80 Cytokine-cytokine receptor interaction 💬
1件: GHR 💬 D11486 💬 Lonapegsomatropin 1件: 78 💬
81 Cytokine-cytokine receptor interaction 💬
1件: GHR 💬 D03297 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
82 Cytokine-cytokine receptor interaction 💬
1件: GHR 💬 D04870 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
83 Cytokine-cytokine receptor interaction 💬
1件: GHR 💬 D05394 💬 Pegvisomant 1件: 78 💬
84 Cytokine-cytokine receptor interaction 💬
1件: GHR 💬 D11194 💬 Somapacitan 1件: 78 💬
85 Cytokine-cytokine receptor interaction 💬
1件: GHR 💬 D02691 💬 Somatotropin 23件:  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬
86 Cytokine-cytokine receptor interaction 💬
1件: GHR 💬 D11193 💬 Somavaratan 1件: 78 💬
87 Dopaminergic synapse 💬
2件: GRIN2A, GRIN2B 💬 D00848 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
88 Dopaminergic synapse 💬
2件: GRIN2A, GRIN2B 💬 D03742 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
89 Dopaminergic synapse 💬
2件: GRIN2A, GRIN2B 💬 D03744 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
90 EGFR tyrosine kinase inhibitor resistance 💬
1件: IGF1R 💬 D03297 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
91 EGFR tyrosine kinase inhibitor resistance 💬
1件: IGF1R 💬 D04870 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
92 Endocrine resistance 💬
1件: IGF1R 💬 D03297 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
93 Endocrine resistance 💬
1件: IGF1R 💬 D04870 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
94 Endocytosis 💬
1件: IGF1R 💬 D03297 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
95 Endocytosis 💬
1件: IGF1R 💬 D04870 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
96 Estrogen signaling pathway 💬
1件: OPRM1 💬 D01355 💬 Tramadol 5件: 46, 70, 78, 226, 271 💬
97 Estrogen signaling pathway 💬
1件: OPRM1 💬 D08623 💬 Tramadol 5件: 46, 70, 78, 226, 271 💬
98 Focal adhesion 💬
1件: IGF1R 💬 D03297 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
99 Focal adhesion 💬
1件: IGF1R 💬 D04870 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
100 FoxO signaling pathway 💬
1件: IGF1R 💬 D03297 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
101 FoxO signaling pathway 💬
1件: IGF1R 💬 D04870 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
102 Gastric acid secretion 💬
1件: SSTR2 💬 D07431 💬 Somatostatin 2件: 67, 78 💬
103 Glioma 💬
1件: IGF1R 💬 D03297 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
104 Glioma 💬
1件: IGF1R 💬 D04870 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
105 Glucagon signaling pathway 💬
1件: GCGR 💬 D00116 💬 Glucagon 1件: 78 💬
106 Glucagon signaling pathway 💬
1件: GCGR 💬 D02118 💬 Glucagon 1件: 78 💬
107 Glucagon signaling pathway 💬
1件: PDE3B 💬 D00528 💬 Caffeine 9件:  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
108 Glucagon signaling pathway 💬
1件: PDE3B 💬 D01453 💬 Caffeine 9件:  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
109 Glutamatergic synapse 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00848 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
110 Glutamatergic synapse 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
111 Glutamatergic synapse 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03744 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
112 Glycerophospholipid metabolism 💬
1件: ACHE 💬 D00670 💬 Donepezil 9件:  5 ,  6 , 13, 46, 78, 124, 127, 156, 206 💬
113 Glycerophospholipid metabolism 💬
1件: ACHE 💬 D07869 💬 Donepezil 9件:  5 ,  6 , 13, 46, 78, 124, 127, 156, 206 💬
114 Growth hormone synthesis, secretion and action 💬
1件: GHR 💬 D11486 💬 Lonapegsomatropin 1件: 78 💬
115 Growth hormone synthesis, secretion and action 💬
1件: GHR 💬 D03297 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
116 Growth hormone synthesis, secretion and action 💬
1件: GHR 💬 D04870 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
117 Growth hormone synthesis, secretion and action 💬
1件: GHR 💬 D05394 💬 Pegvisomant 1件: 78 💬
118 Growth hormone synthesis, secretion and action 💬
1件: GHR 💬 D11194 💬 Somapacitan 1件: 78 💬
119 Growth hormone synthesis, secretion and action 💬
1件: GHR 💬 D02691 💬 Somatotropin 23件:  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬
120 Growth hormone synthesis, secretion and action 💬
1件: GHR 💬 D11193 💬 Somavaratan 1件: 78 💬
121 Growth hormone synthesis, secretion and action 💬
1件: GHRHR 💬 D08523 💬 Somatorelin 2件: 13, 78 💬
122 Growth hormone synthesis, secretion and action 💬
1件: GHRHR 💬 D06655 💬 Tesamorelin 2件: 78, 265 💬
123 Growth hormone synthesis, secretion and action 💬
1件: GHSR 💬 D10563 💬 Macimorelin 1件: 78 💬
124 Growth hormone synthesis, secretion and action 💬
4件: SSTR1, SSTR2, SSTR3, SSTR5 💬 D07431 💬 Somatostatin 2件: 67, 78 💬
125 Hepatocellular carcinoma 💬
1件: IGF1R 💬 D03297 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
126 Hepatocellular carcinoma 💬
1件: IGF1R 💬 D04870 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
127 HIF-1 signaling pathway 💬
1件: IGF1R 💬 D03297 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
128 HIF-1 signaling pathway 💬
1件: IGF1R 💬 D04870 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
129 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D00903 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
130 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D00904 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
131 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D07816 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
132 Human papillomavirus infection 💬
1件: PTGS2 💬 D00903 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
133 Human papillomavirus infection 💬
1件: PTGS2 💬 D00904 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
134 Human papillomavirus infection 💬
1件: PTGS2 💬 D07816 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
135 Huntington disease 💬
2件: GRIN1, GRIN2B 💬 D00848 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
136 Huntington disease 💬
2件: GRIN1, GRIN2B 💬 D03742 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
137 Huntington disease 💬
2件: GRIN1, GRIN2B 💬 D03744 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
138 Huntington disease 💬
1件: PPARG 💬 D00945 💬 Pioglitazone 17件:  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
139 Huntington disease 💬
1件: PPARG 💬 D08378 💬 Pioglitazone 17件:  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
140 IL-17 signaling pathway 💬
1件: PTGS2 💬 D00903 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
141 IL-17 signaling pathway 💬
1件: PTGS2 💬 D00904 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
142 IL-17 signaling pathway 💬
1件: PTGS2 💬 D07816 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
143 Insulin secretion 💬
1件: GLP1R 💬 D04121 💬 Exenatide 6件:  6 , 17, 72, 78, 193, 233 💬
144 Insulin signaling pathway 💬
1件: PDE3B 💬 D00528 💬 Caffeine 9件:  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
145 Insulin signaling pathway 💬
1件: PDE3B 💬 D01453 💬 Caffeine 9件:  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
146 JAK-STAT signaling pathway 💬
1件: GHR 💬 D11486 💬 Lonapegsomatropin 1件: 78 💬
147 JAK-STAT signaling pathway 💬
1件: GHR 💬 D03297 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
148 JAK-STAT signaling pathway 💬
1件: GHR 💬 D04870 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
149 JAK-STAT signaling pathway 💬
1件: GHR 💬 D05394 💬 Pegvisomant 1件: 78 💬
150 JAK-STAT signaling pathway 💬
1件: GHR 💬 D11194 💬 Somapacitan 1件: 78 💬
151 JAK-STAT signaling pathway 💬
1件: GHR 💬 D02691 💬 Somatotropin 23件:  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬
152 JAK-STAT signaling pathway 💬
1件: GHR 💬 D11193 💬 Somavaratan 1件: 78 💬
153 Kaposi sarcoma-associated herpesvirus infection 💬
1件: PTGS2 💬 D00903 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
154 Kaposi sarcoma-associated herpesvirus infection 💬
1件: PTGS2 💬 D00904 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
155 Kaposi sarcoma-associated herpesvirus infection 💬
1件: PTGS2 💬 D07816 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
156 Leishmaniasis 💬
1件: PTGS2 💬 D00903 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
157 Leishmaniasis 💬
1件: PTGS2 💬 D00904 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
158 Leishmaniasis 💬
1件: PTGS2 💬 D07816 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
159 Lipid and atherosclerosis 💬
1件: PPARG 💬 D00945 💬 Pioglitazone 17件:  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
160 Lipid and atherosclerosis 💬
1件: PPARG 💬 D08378 💬 Pioglitazone 17件:  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
161 Long-term depression 💬
1件: IGF1R 💬 D03297 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
162 Long-term depression 💬
1件: IGF1R 💬 D04870 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
163 Long-term potentiation 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00848 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
164 Long-term potentiation 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
165 Long-term potentiation 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03744 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
166 Longevity regulating pathway 💬
1件: IGF1R 💬 D03297 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
167 Longevity regulating pathway 💬
1件: IGF1R 💬 D04870 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
168 Longevity regulating pathway 💬
1件: PPARG 💬 D00945 💬 Pioglitazone 17件:  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
169 Longevity regulating pathway 💬
1件: PPARG 💬 D08378 💬 Pioglitazone 17件:  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
170 Longevity regulating pathway - multiple species 💬
1件: IGF1R 💬 D03297 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
171 Longevity regulating pathway - multiple species 💬
1件: IGF1R 💬 D04870 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
172 MAPK signaling pathway 💬
1件: IGF1R 💬 D03297 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
173 MAPK signaling pathway 💬
1件: IGF1R 💬 D04870 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
174 Melanoma 💬
1件: IGF1R 💬 D03297 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
175 Melanoma 💬
1件: IGF1R 💬 D04870 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
176 Metabolic pathways 💬
1件: CYP19A1 💬 D00960 💬 Anastrozole 3件: 78, 86, 193 💬
177 Metabolic pathways 💬
9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 D00528 💬 Caffeine 9件:  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
178 Metabolic pathways 💬
9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 D01453 💬 Caffeine 9件:  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
179 Metabolic pathways 💬
2件: PTGS1, PTGS2 💬 D00903 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
180 Metabolic pathways 💬
2件: PTGS1, PTGS2 💬 D00904 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
181 Metabolic pathways 💬
2件: PTGS1, PTGS2 💬 D07816 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
182 MicroRNAs in cancer 💬
1件: PTGS2 💬 D00903 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
183 MicroRNAs in cancer 💬
1件: PTGS2 💬 D00904 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
184 MicroRNAs in cancer 💬
1件: PTGS2 💬 D07816 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
185 Morphine addiction 💬
9件: ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 D00528 💬 Caffeine 9件:  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
186 Morphine addiction 💬
9件: ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 D01453 💬 Caffeine 9件:  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
187 Morphine addiction 💬
1件: OPRM1 💬 D01355 💬 Tramadol 5件: 46, 70, 78, 226, 271 💬
188 Morphine addiction 💬
1件: OPRM1 💬 D08623 💬 Tramadol 5件: 46, 70, 78, 226, 271 💬
189 mTOR signaling pathway 💬
1件: IGF1R 💬 D03297 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
190 mTOR signaling pathway 💬
1件: IGF1R 💬 D04870 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
191 Neuroactive ligand-receptor interaction 💬
2件: ADORA1, ADORA2A 💬 D00528 💬 Caffeine 9件:  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
192 Neuroactive ligand-receptor interaction 💬
2件: ADORA1, ADORA2A 💬 D01453 💬 Caffeine 9件:  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
193 Neuroactive ligand-receptor interaction 💬
3件: ADRA2A, ADRA2B, ADRA2C 💬 D00281 💬 Clonidine 4件:  6 , 65, 70, 78 💬
194 Neuroactive ligand-receptor interaction 💬
3件: ADRA2A, ADRA2B, ADRA2C 💬 D00604 💬 Clonidine 4件:  6 , 65, 70, 78 💬
195 Neuroactive ligand-receptor interaction 💬
1件: GCGR 💬 D00116 💬 Glucagon 1件: 78 💬
196 Neuroactive ligand-receptor interaction 💬
1件: GCGR 💬 D02118 💬 Glucagon 1件: 78 💬
197 Neuroactive ligand-receptor interaction 💬
1件: GHR 💬 D11486 💬 Lonapegsomatropin 1件: 78 💬
198 Neuroactive ligand-receptor interaction 💬
1件: GHR 💬 D03297 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
199 Neuroactive ligand-receptor interaction 💬
1件: GHR 💬 D04870 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
200 Neuroactive ligand-receptor interaction 💬
1件: GHR 💬 D05394 💬 Pegvisomant 1件: 78 💬
201 Neuroactive ligand-receptor interaction 💬
1件: GHR 💬 D11194 💬 Somapacitan 1件: 78 💬
202 Neuroactive ligand-receptor interaction 💬
1件: GHR 💬 D02691 💬 Somatotropin 23件:  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬
203 Neuroactive ligand-receptor interaction 💬
1件: GHR 💬 D11193 💬 Somavaratan 1件: 78 💬
204 Neuroactive ligand-receptor interaction 💬
1件: GHRHR 💬 D08523 💬 Somatorelin 2件: 13, 78 💬
205 Neuroactive ligand-receptor interaction 💬
1件: GHRHR 💬 D06655 💬 Tesamorelin 2件: 78, 265 💬
206 Neuroactive ligand-receptor interaction 💬
1件: GHSR 💬 D10563 💬 Macimorelin 1件: 78 💬
207 Neuroactive ligand-receptor interaction 💬
1件: GLP1R 💬 D04121 💬 Exenatide 6件:  6 , 17, 72, 78, 193, 233 💬
208 Neuroactive ligand-receptor interaction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00848 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
209 Neuroactive ligand-receptor interaction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
210 Neuroactive ligand-receptor interaction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03744 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
211 Neuroactive ligand-receptor interaction 💬
1件: MC2R 💬 D00146 💬 Corticotropin 15件:  2 , 13, 14, 46, 49, 50, 66, 75, 78, 81, 84, 145, 193, 205, 222 💬
212 Neuroactive ligand-receptor interaction 💬
1件: MC2R 💬 D00284 💬 Tetracosactide 5件: 78, 83, 113, 145, 222 💬
213 Neuroactive ligand-receptor interaction 💬
1件: NR3C1 💬 D00088 💬 Hydrocortisone 11件:  6 , 41, 46, 53, 75, 78, 81, 83, 97, 98, 299 💬
214 Neuroactive ligand-receptor interaction 💬
1件: OPRM1 💬 D01355 💬 Tramadol 5件: 46, 70, 78, 226, 271 💬
215 Neuroactive ligand-receptor interaction 💬
1件: OPRM1 💬 D08623 💬 Tramadol 5件: 46, 70, 78, 226, 271 💬
216 Neuroactive ligand-receptor interaction 💬
5件: SSTR1, SSTR2, SSTR3, SSTR4, SSTR5 💬 D07431 💬 Somatostatin 2件: 67, 78 💬
217 Neuroactive ligand-receptor interaction 💬
2件: THRA, THRB 💬 D01010 💬 Levothyroxine 5件: 19, 49, 78, 80, 222 💬
218