Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Chemical carcinogenesis - reactive oxygen species 💬
1件: ABL1 💬 D01441 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
2 Chemical carcinogenesis - reactive oxygen species 💬
1件: ABL1 💬 D08066 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
3 Chemical carcinogenesis - reactive oxygen species 💬
1件: ABL1 💬 D08953 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬
4 Chemical carcinogenesis - reactive oxygen species 💬
2件: ABL1, SRC 💬 D03252 💬 Bosutinib 2件:  2 , 67 💬
5 Chemical carcinogenesis - reactive oxygen species 💬
2件: ABL1, SRC 💬 D03658 💬 Dasatinib 2件: 51, 85 💬
6 Chemical carcinogenesis - reactive oxygen species 💬
2件: ABL1, SRC 💬 D06414 💬 Dasatinib 2件: 51, 85 💬
7 Chemical carcinogenesis - reactive oxygen species 💬
2件: ABL1, SRC 💬 D09664 💬 Saracatinib 3件:  6 , 89, 272 💬
8 Chemical carcinogenesis - reactive oxygen species 💬
1件: BRAF 💬 D10064 💬 Dabrafenib 1件: 34 💬
9 Chemical carcinogenesis - reactive oxygen species 💬
2件: BRAF, RAF1 💬 D06272 💬 Sorafenib 2件: 34, 86 💬
10 Chemical carcinogenesis - reactive oxygen species 💬
2件: BRAF, RAF1 💬 D08524 💬 Sorafenib 2件: 34, 86 💬
11 Chemical carcinogenesis - reactive oxygen species 💬
1件: EGFR 💬 D03455 💬 Cetuximab 5件: 34, 51, 86, 89, 331 💬
12 Chemical carcinogenesis - reactive oxygen species 💬
1件: EGFR 💬 D04023 💬 Erlotinib 1件: 94 💬
13 Chemical carcinogenesis - reactive oxygen species 💬
1件: EGFR 💬 D07907 💬 Erlotinib 1件: 94 💬
14 Chemical carcinogenesis - reactive oxygen species 💬
1件: EGFR 💬 D01977 💬 Gefitinib 1件: 75 💬
15 Chemical carcinogenesis - reactive oxygen species 💬
1件: EGFR 💬 D11251 💬 Icotinib 1件: 34 💬
16 Chemical carcinogenesis - reactive oxygen species 💬
1件: EGFR 💬 D04024 💬 Lapatinib 3件: 34, 74, 75 💬
17 Chemical carcinogenesis - reactive oxygen species 💬
1件: EGFR 💬 D08108 💬 Lapatinib 3件: 34, 74, 75 💬
18 Chemical carcinogenesis - reactive oxygen species 💬
1件: EGFR 💬 D11772 💬 Tesevatinib 1件: 67 💬
19 Chemical carcinogenesis - reactive oxygen species 💬
1件: HMOX1 💬 D05922 💬 Stannsoporfin 1件: 254 💬
20 Chemical carcinogenesis - reactive oxygen species 💬
1件: KEAP1 💬 D03846 💬 Dimethyl fumarate 5件: 13, 49, 51, 86, 296 💬
21 Chemical carcinogenesis - reactive oxygen species 💬
2件: MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib 1件: 34 💬
22 Chemical carcinogenesis - reactive oxygen species 💬
2件: MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib 1件: 280 💬
23 Chemical carcinogenesis - reactive oxygen species 💬
2件: MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib 1件: 34 💬
24 Chemical carcinogenesis - reactive oxygen species 💬
2件: MAP2K1, MAP2K2 💬 D10175 💬 Trametinib 4件:  2 , 34, 279, 280 💬
25 Chemical carcinogenesis - reactive oxygen species 💬
1件: MAP3K5 💬 D10988 💬 Selonsertib 1件: 86 💬
26 Chemical carcinogenesis - reactive oxygen species 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod 2件: 113, 222 💬
27 Chemical carcinogenesis - reactive oxygen species 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod 1件:  8  💬
28 Chemical carcinogenesis - reactive oxygen species 💬
1件: MET 💬 D10062 💬 Cabozantinib 1件: 34 💬
29 Chemical carcinogenesis - reactive oxygen species 💬
1件: NFE2L2 💬 D10964 💬 Omaveloxolone 1件: 18 💬
30 Chemical carcinogenesis - reactive oxygen species 💬
1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
31 Chemical carcinogenesis - reactive oxygen species 💬
1件: NQO1 💬 D00564 💬 Warfarin 13件:  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
32 Chemical carcinogenesis - reactive oxygen species 💬
1件: NQO1 💬 D01280 💬 Warfarin 13件:  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
33 Chemical carcinogenesis - reactive oxygen species 💬
1件: NQO1 💬 D08682 💬 Warfarin 13件:  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
34 Chemical carcinogenesis - reactive oxygen species 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
35 Chemical carcinogenesis - reactive oxygen species 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
36 Chemical carcinogenesis - reactive oxygen species 💬
1件: PRKCD 💬 D09671 💬 Sotrastaurin 1件: 97 💬
37 Chemical carcinogenesis - reactive oxygen species 💬
1件: RELA 💬 D12181 💬 Edasalonexent 1件: 113 💬
38 Chemical carcinogenesis - reactive oxygen species 💬
1件: SOD1 💬 D11811 💬 Tofersen 1件:  2  💬
39 Chemical carcinogenesis - reactive oxygen species 💬
1件: VEGFA 💬 D09574 💬 Aflibercept 2件: 90, 166 💬
40 Chemical carcinogenesis - reactive oxygen species 💬
1件: VEGFA 💬 D06409 💬 Bevacizumab 9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
41 Chemical carcinogenesis - reactive oxygen species 💬
1件: VEGFA 💬 D05697 💬 Ranibizumab 4件: 34, 166, 227, 301 💬