Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Neutrophil extracellular trap formation 💬
1件: C3 💬 D11613 💬 Pegcetacoplan 3件:  2 , 62, 222 💬
2 Neutrophil extracellular trap formation 💬
1件: C5 💬 D11696 💬 Crovalimab 2件: 62, 109 💬
3 Neutrophil extracellular trap formation 💬
1件: C5 💬 D03940 💬 Eculizumab 7件: 11, 13, 14, 61, 62, 109, 222 💬
4 Neutrophil extracellular trap formation 💬
1件: C5 💬 D11473 💬 Nomacopan 3件: 62, 109, 162 💬
5 Neutrophil extracellular trap formation 💬
1件: C5 💬 D11477 💬 Pozelimab 2件: 11, 62 💬
6 Neutrophil extracellular trap formation 💬
1件: C5 💬 D11054 💬 Ravulizumab 7件:  2 , 11, 13, 50, 62, 66, 109 💬
7 Neutrophil extracellular trap formation 💬
1件: C5 💬 D11838 💬 Vilobelimab 3件: 43, 44, 269 💬
8 Neutrophil extracellular trap formation 💬
1件: C5AR1 💬 D11093 💬 Avacopan 3件: 43, 44, 222 💬
9 Neutrophil extracellular trap formation 💬
1件: ELANE 💬 D03788 💬 Sivelestat 3件: 13, 85, 96 💬
10 Neutrophil extracellular trap formation 💬
11件: HDAC1, HDAC10, HDAC11, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, HDAC9 💬 D06320 💬 Vorinostat 3件: 19, 75, 96 💬
11 Neutrophil extracellular trap formation 💬
1件: ITGAL 💬 D03959 💬 Efalizumab 9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
12 Neutrophil extracellular trap formation 💬
2件: MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib 1件: 34 💬
13 Neutrophil extracellular trap formation 💬
2件: MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib 1件: 280 💬
14 Neutrophil extracellular trap formation 💬
2件: MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib 1件: 34 💬
15 Neutrophil extracellular trap formation 💬
2件: MAP2K1, MAP2K2 💬 D10175 💬 Trametinib 4件:  2 , 34, 279, 280 💬
16 Neutrophil extracellular trap formation 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod 2件: 113, 222 💬
17 Neutrophil extracellular trap formation 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod 1件:  8  💬
18 Neutrophil extracellular trap formation 💬
1件: MPO 💬 D11684 💬 Verdiperstat 3件:  2 , 17, 127 💬
19 Neutrophil extracellular trap formation 💬
1件: MTOR 💬 D02714 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
20 Neutrophil extracellular trap formation 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
21 Neutrophil extracellular trap formation 💬
1件: MTOR 💬 D06068 💬 Temsirolimus 4件: 13, 34, 89, 331 💬
22 Neutrophil extracellular trap formation 💬
1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
23 Neutrophil extracellular trap formation 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
24 Neutrophil extracellular trap formation 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
25 Neutrophil extracellular trap formation 💬
1件: RAF1 💬 D06272 💬 Sorafenib 2件: 34, 86 💬
26 Neutrophil extracellular trap formation 💬
1件: RAF1 💬 D08524 💬 Sorafenib 2件: 34, 86 💬
27 Neutrophil extracellular trap formation 💬
1件: RELA 💬 D12181 💬 Edasalonexent 1件: 113 💬
28 Neutrophil extracellular trap formation 💬
1件: SRC 💬 D03252 💬 Bosutinib 2件:  2 , 67 💬
29 Neutrophil extracellular trap formation 💬
1件: SRC 💬 D03658 💬 Dasatinib 2件: 51, 85 💬
30 Neutrophil extracellular trap formation 💬
1件: SRC 💬 D06414 💬 Dasatinib 2件: 51, 85 💬
31 Neutrophil extracellular trap formation 💬
1件: SRC 💬 D09664 💬 Saracatinib 3件:  6 , 89, 272 💬
32 Neutrophil extracellular trap formation 💬
1件: SYK 💬 D09347 💬 Fostamatinib 4件: 46, 49, 61, 66 💬
33 Neutrophil extracellular trap formation 💬
1件: TLR7 💬 D02500 💬 Imiquimod 2件: 34, 51 💬
34 Neutrophil extracellular trap formation 💬
1件: VWF 💬 D11160 💬 Caplacizumab 1件: 64 💬