Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Signaling pathways regulating pluripotency of stem cells 💬
1件: ACVR2A 💬 D09670 💬 Sotatercept 2件: 86, 284 💬
2 Signaling pathways regulating pluripotency of stem cells 💬
2件: ACVR2A, ACVR2B 💬 D10620 💬 Bimagrumab 1件: 15 💬
3 Signaling pathways regulating pluripotency of stem cells 💬
1件: BMPR2 💬 D03779 💬 Dibotermin alfa 1件: 34 💬
4 Signaling pathways regulating pluripotency of stem cells 💬
3件: FGFR1, FGFR2, FGFR3 💬 D11589 💬 Infigratinib 1件: 276 💬
5 Signaling pathways regulating pluripotency of stem cells 💬
3件: FGFR1, FGFR2, FGFR3 💬 D10481 💬 Nintedanib 5件: 51, 85, 89, 227, 228 💬
6 Signaling pathways regulating pluripotency of stem cells 💬
1件: FGFR2 💬 D05338 💬 Palifermin 5件: 13, 36, 38, 39, 65 💬
7 Signaling pathways regulating pluripotency of stem cells 💬
1件: IGF1R 💬 D09925 💬 Linsitinib 1件: 232 💬
8 Signaling pathways regulating pluripotency of stem cells 💬
1件: IGF1R 💬 D03297 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
9 Signaling pathways regulating pluripotency of stem cells 💬
1件: IGF1R 💬 D04870 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
10 Signaling pathways regulating pluripotency of stem cells 💬
1件: IGF1R 💬 D09680 💬 Teprotumumab 1件: 51 💬
11 Signaling pathways regulating pluripotency of stem cells 💬
1件: JAK1 💬 D10871 💬 Filgotinib 6件: 46, 53, 96, 97, 222, 271 💬
12 Signaling pathways regulating pluripotency of stem cells 💬
1件: JAK1 💬 D10944 💬 Itacitinib 5件: 46, 51, 60, 97, 228 💬
13 Signaling pathways regulating pluripotency of stem cells 💬
1件: JAK1 💬 D10994 💬 Upadacitinib 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
14 Signaling pathways regulating pluripotency of stem cells 💬
2件: JAK1, JAK2 💬 D10308 💬 Baricitinib 13件: 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
15 Signaling pathways regulating pluripotency of stem cells 💬
2件: JAK1, JAK2 💬 D09959 💬 Ruxolitinib 1件: 228 💬
16 Signaling pathways regulating pluripotency of stem cells 💬
3件: JAK1, JAK2, JAK3 💬 D10653 💬 Peficitinib 1件: 46 💬
17 Signaling pathways regulating pluripotency of stem cells 💬
3件: JAK1, JAK2, JAK3 💬 D09970 💬 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
18 Signaling pathways regulating pluripotency of stem cells 💬
2件: MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib 1件: 34 💬
19 Signaling pathways regulating pluripotency of stem cells 💬
2件: MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib 1件: 280 💬
20 Signaling pathways regulating pluripotency of stem cells 💬
2件: MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib 1件: 34 💬
21 Signaling pathways regulating pluripotency of stem cells 💬
2件: MAP2K1, MAP2K2 💬 D10175 💬 Trametinib 4件:  2 , 34, 279, 280 💬
22 Signaling pathways regulating pluripotency of stem cells 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod 2件: 113, 222 💬
23 Signaling pathways regulating pluripotency of stem cells 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod 1件:  8  💬
24 Signaling pathways regulating pluripotency of stem cells 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
25 Signaling pathways regulating pluripotency of stem cells 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
26 Signaling pathways regulating pluripotency of stem cells 💬
1件: RAF1 💬 D06272 💬 Sorafenib 2件: 34, 86 💬
27 Signaling pathways regulating pluripotency of stem cells 💬
1件: RAF1 💬 D08524 💬 Sorafenib 2件: 34, 86 💬