Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 TNF signaling pathway 💬
 4件: CCL2, IL1B, IL6, TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬
2 TNF signaling pathway 💬
 1件: CSF2 💬 Otilimab 💬 Otilimab 1件: 46 💬 💬
3 TNF signaling pathway 💬
 1件: IL1B 💬 Canakinumab 💬 Canakinumab 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬
4 TNF signaling pathway 💬
 1件: IL1B 💬 Gevokizumab 💬 Gevokizumab 4件: 41, 50, 56, 269 💬 💬
5 TNF signaling pathway 💬
 1件: IL1B 💬 Rilonacept 💬 Rilonacept 4件: 51, 106, 107, 266 💬 💬
6 TNF signaling pathway 💬
 1件: IL6 💬 Olokizumab 💬 Olokizumab 2件: 46, 96 💬 💬
7 TNF signaling pathway 💬
 1件: IL6 💬 Siltuximab 💬 Siltuximab 2件: 28, 331 💬 💬
8 TNF signaling pathway 💬
 1件: IL6 💬 Sirukumab 💬 Sirukumab 2件: 41, 46 💬 💬
9 TNF signaling pathway 💬
 2件: IL6, TNF 💬 Pomalidomide 💬 Pomalidomide 5件: 28, 51, 85, 227, 331 💬 💬
10 TNF signaling pathway 💬
 1件: LTA 💬 Pateclizumab 💬 Pateclizumab 1件: 46 💬 💬
11 TNF signaling pathway 💬
 2件: LTA, TNF 💬 Etanercept 💬 Etanercept 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 💬
12 TNF signaling pathway 💬
 1件: MAP2K1 💬 Binimetinib 💬 Binimetinib 1件: 34 💬 💬
13 TNF signaling pathway 💬
 1件: MAP2K1 💬 Cobimetinib 💬 Cobimetinib 1件: 280 💬 💬
14 TNF signaling pathway 💬
 1件: MAP2K1 💬 Mirdametinib 💬 Mirdametinib 1件: 34 💬 💬
15 TNF signaling pathway 💬
 1件: MAP2K1 💬 Selumetinib 💬 Selumetinib 1件: 34 💬 💬
16 TNF signaling pathway 💬
 1件: MAP2K1 💬 Trametinib 💬 Trametinib 4件:  2 , 34, 279, 280 💬 💬
17 TNF signaling pathway 💬
 1件: MAP3K5 💬 Selonsertib 💬 Selonsertib 1件: 86 💬 💬
18 TNF signaling pathway 💬
 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 Losmapimod 💬 Losmapimod 2件: 113, 222 💬 💬
19 TNF signaling pathway 💬
 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 Neflamapimod 💬 Neflamapimod 1件:  8  💬 💬
20 TNF signaling pathway 💬
 1件: NFKB1 💬 Iguratimod 💬 Iguratimod 5件: 46, 51, 53, 271, 300 💬 💬
21 TNF signaling pathway 💬
 1件: PIK3CA 💬 Alpelisib 💬 Alpelisib 1件: 138 💬 💬
22 TNF signaling pathway 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬 💬
23 TNF signaling pathway 💬
 1件: PIK3CD 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬 💬
24 TNF signaling pathway 💬
 1件: PTGS2 💬 Aceclofenac 💬 Aceclofenac 1件: 46 💬 💬
25 TNF signaling pathway 💬
 1件: PTGS2 💬 Acetaminophen 💬 Acetaminophen 15件:  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬
26 TNF signaling pathway 💬
 1件: PTGS2 💬 Aspirin 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬 💬
27 TNF signaling pathway 💬
 1件: PTGS2 💬 Celecoxib 💬 Celecoxib 10件:  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬
28 TNF signaling pathway 💬
 1件: PTGS2 💬 Diclofenac 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬 💬
29 TNF signaling pathway 💬
 1件: PTGS2 💬 Diflunisal 💬 Diflunisal 1件: 28 💬 💬
30 TNF signaling pathway 💬
 1件: PTGS2 💬 Etodolac 💬 Etodolac 1件: 46 💬 💬
31 TNF signaling pathway 💬
 1件: PTGS2 💬 Etoricoxib 💬 Etoricoxib 2件: 46, 271 💬 💬
32 TNF signaling pathway 💬
 1件: PTGS2 💬 Flurbiprofen 💬 Flurbiprofen 3件: 13, 21, 46 💬 💬
33 TNF signaling pathway 💬
 1件: PTGS2 💬 Ibuprofen 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬 💬
34 TNF signaling pathway 💬
 1件: PTGS2 💬 Indomethacin 💬 Indomethacin 3件: 225, 271, 298 💬 💬
35 TNF signaling pathway 💬
 1件: PTGS2 💬 Ketoprofen 💬 Ketoprofen 1件: 46 💬 💬
36 TNF signaling pathway 💬
 1件: PTGS2 💬 Ketorolac 💬 Ketorolac 2件: 70, 226 💬 💬
37 TNF signaling pathway 💬
 1件: PTGS2 💬 Loxoprofen 💬 Loxoprofen 2件: 46, 271 💬 💬
38 TNF signaling pathway 💬
 1件: PTGS2 💬 Lumiracoxib 💬 Lumiracoxib 1件: 46 💬 💬
39 TNF signaling pathway 💬
 1件: PTGS2 💬 Meloxicam 💬 Meloxicam 4件: 46, 49, 271, 296 💬 💬
40 TNF signaling pathway 💬
 1件: PTGS2 💬 Naproxen 💬 Naproxen 4件: 13, 46, 107, 271 💬 💬
41 TNF signaling pathway 💬
 1件: PTGS2 💬 Nimesulide 💬 Nimesulide 1件: 46 💬 💬
42 TNF signaling pathway 💬
 1件: PTGS2 💬 Parecoxib 💬 Parecoxib 2件: 46, 271 💬 💬
43 TNF signaling pathway 💬
 1件: PTGS2 💬 Rofecoxib 💬 Rofecoxib 1件: 46 💬 💬
44 TNF signaling pathway 💬
 1件: PTGS2 💬 Salsalate 💬 Salsalate 1件:  5  💬 💬
45 TNF signaling pathway 💬
 1件: PTGS2 💬 Sulindac 💬 Sulindac 1件: 206 💬 💬
46 TNF signaling pathway 💬
 1件: PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid 1件:  5  💬 💬
47 TNF signaling pathway 💬
 1件: PTGS2 💬 Valdecoxib 💬 Valdecoxib 1件: 46 💬 💬
48 TNF signaling pathway 💬
 1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬 💬
49 TNF signaling pathway 💬
 1件: TNF 💬 Adalimumab 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬
50 TNF signaling pathway 💬
 1件: TNF 💬 Certolizumab pegol 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬 💬
51 TNF signaling pathway 💬
 1件: TNF 💬 Golimumab 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬
52 TNF signaling pathway 💬
 1件: TNF 💬 Infliximab 💬 Infliximab 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬
53 TNF signaling pathway 💬
 1件: TNF 💬 Lenalidomide 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬 💬
54 TNF signaling pathway 💬
 1件: TNF 💬 Ozoralizumab 💬 Ozoralizumab 1件: 46 💬 💬
55 TNF signaling pathway 💬
 1件: TNF 💬 Pegsunercept 💬 Pegsunercept 1件: 46 💬 💬
56 TNF signaling pathway 💬
 1件: TNF 💬 Thalidomide 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬