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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1ABP 959----[1] 62 💬
2ABP 959 - biosimilar to eculizumab[1] Eculizumab[1] Eculizumab 💬[1] C5 💬[11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 62 💬
3ABP 959 - proposed biosimilar to eculizumab[1] Eculizumab[1] Eculizumab 💬[1] C5 💬[11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 62 💬
4ACH-0144471----[2] 62, 222 💬
5ACH-0145228----[1] 62 💬
6Act-HiB[1] Haemophilus influenzae type B strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen---[4] 14, 61, 62, 222 💬
7ACT-HIB Polvere e solvente per soluzione iniettabile in siringa preriempita 0,5 ml[1] Haemophilus influenzae type B strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen---[2] 61, 62 💬
8ActHIB[1] Haemophilus influenzae type B strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen---[2] 62, 66 💬
9ACTHIB - POLVERE E SOLVENTE PER SOLUZIONE INIETTABILE 1 FLACONCINO POLVERE+1 SIRINGA PRERIEMPITA SOLVENTE 0.5 ML[1] Haemophilus influenzae type B strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen---[2] 62, 66 💬
10ALN-62643----[2] 62, 109 💬
11ALN-CC5----[4] 11, 62, 66, 109 💬
12ALXN1102----[1] 62 💬
13ALXN1103----[1] 62 💬
14ALXN1210----[7] 2, 11, 13, 50, 62, 66, 109 💬
15ALXN2040----[1] 62 💬
16ALXN2040 (ACH-0144471)----[1] 62 💬
17ALXN2050----[2] 11, 62 💬
18Anti-C5 antibody----[4] 11, 14, 62, 109 💬
19Anti-Thymocyte Globulin----[18] 11, 13, 14, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 164, 283, 284, 285 💬
20APL-2----[5] 2, 61, 62, 66, 222 💬
21ARO-C3----[2] 62, 66 💬
22Aspaveli[1] Pegcetacoplan[1] Pegcetacoplan 💬[1] C3 💬[17] Alcoholic liver disease, Chagas disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Phagosome, Shigellosis, Staphylococcus aureus infection, Systemic lupus erythematosus, Tuberculosis, Viral carcinogenesis 💬[3] 2, 62, 222 💬
23BCD-148----[1] 62 💬
24BCX9930----[3] 62, 66, 222 💬
25BCX9930 hydrochloride----[3] 62, 66, 222 💬
26BCX9930 monotherapy----[1] 62 💬
27Bexsero[4] Neisseria meningitidis serogroup B strain NZ98/254 outer membrane vesicle,
Neisseria meningitidis serogroup b fhbp fusion protein antigen,
Neisseria meningitidis serogroup b nada protein antigen,
Neisseria meningitidis serogroup b nhba fusion protein antigen		---[6] 11, 13, 61, 62, 66, 222 💬
28BEXSERO - SOSPENSIONE INIETTABILE - USO INTRAMUSCOLARE - SIRINGA P[4] Neisseria meningitidis serogroup B strain NZ98/254 outer membrane vesicle,
Neisseria meningitidis serogroup b fhbp fusion protein antigen,
Neisseria meningitidis serogroup b nada protein antigen,
Neisseria meningitidis serogroup b nhba fusion protein antigen		---[1] 62 💬
29BEXSERO – Sospensione iniettabile – Siringa preriempita[4] Neisseria meningitidis serogroup B strain NZ98/254 outer membrane vesicle,
Neisseria meningitidis serogroup b fhbp fusion protein antigen,
Neisseria meningitidis serogroup b nada protein antigen,
Neisseria meningitidis serogroup b nhba fusion protein antigen		---[2] 61, 62 💬
30Bryostatin 1[1] Bryostatin 1---[1] 62 💬
31C5 inh MAb, SKY59, RO/CH7092230----[2] 62, 109 💬
32C5 Inhibitor----[1] 62 💬
33Campath[1] Alemtuzumab[1] Alemtuzumab 💬[1] CD52 💬-[12] 19, 20, 49, 51, 60, 62, 65, 164, 234, 283, 285, 326 💬
34Campath, Chemo and/or TBI Allo SCT[1] Alemtuzumab[1] Alemtuzumab 💬[1] CD52 💬-[3] 60, 62, 283 💬
35Cemdisiran[1] Cemdisiran---[4] 11, 62, 66, 109 💬
36Combination Product: Ravulizumab OBDS[1] Ravulizumab[1] Ravulizumab 💬[1] C5 💬[11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 62 💬
37COVERSIN[1] Nomacopan[1] Nomacopan 💬[1] C5 💬[11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[2] 62, 109 💬
38CROVALIMAB[1] Crovalimab[1] Crovalimab 💬[1] C5 💬[11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[2] 62, 109 💬
39Cyclophosphamide[1] Cyclophosphamide[2] Cyclophosphamide ,
Cyclophosphamide 💬		--[44] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331 💬
40Cyclosporin[1] Cyclosporine[1] Cyclosporine 💬[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[17] 38, 46, 49, 50, 53, 56, 60, 62, 63, 93, 95, 97, 113, 164, 222, 274, 326 💬
41Cyclosporin A[1] Cyclosporine[1] Cyclosporine 💬[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[11] 46, 49, 53, 56, 60, 62, 63, 93, 95, 113, 164 💬
42Cyclosporin A+Glucocorticoids[1] Cyclosporine[1] Cyclosporine 💬[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[2] 60, 62 💬
43Cyclosporine[1] Cyclosporine[1] Cyclosporine 💬[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[37] 11, 19, 20, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 107, 162, 164, 222, 226, 228, 234, 283, 284, 285, 302 💬
44Cytoreductive regimen followed by a CD34+E- selected allogeneic stem cell transplant----[1] 62 💬
45DANICOPAN[1] Danicopan[1] Danicopan 💬[1] CFD 💬[3] Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection 💬[1] 62 💬
46Danicopan (ALXN2040)[1] Danicopan[1] Danicopan 💬[1] CFD 💬[3] Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection 💬[1] 62 💬
47Dextran[1] Dextran[1] Dextran 1 💬--[4] 2, 62, 96, 97 💬
48ECULIZUMAB[1] Eculizumab[1] Eculizumab 💬[1] C5 💬[11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[7] 11, 13, 14, 61, 62, 109, 222 💬
49Elizaria®----[1] 62 💬
50Fc- and CDR-modified humanised monoclonal antibody against C5----[3] 11, 62, 109 💬
51Filgrastim[1] Filgrastim[1] Filgrastim 💬[1] CSF3R 💬[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[28] 2, 6, 13, 25, 26, 28, 34, 35, 38, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
52Fludarabine[1] Fludarabine[1] Fludarabine 💬[1] RRM1 💬[6] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬[19] 11, 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬
53Fludarabine phosphate[2] Fludarabine,
Phosphate ion		[1] Fludarabine 💬[1] RRM1 💬[6] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬[12] 28, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285, 286 💬
54G-CSF[1] Filgrastim[1] Filgrastim 💬[1] CSF3R 💬[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[16] 2, 6, 11, 13, 16, 22, 47, 51, 60, 62, 65, 85, 96, 284, 285, 331 💬
55Gelatin[1] Gelatin[2] Gelatin ,
Donkey glue 💬		--[5] 28, 62, 78, 97, 269 💬
56Glucocorticoids----[8] 40, 41, 43, 44, 60, 62, 75, 300 💬
57H5G1.1-mAb----[3] 13, 50, 62 💬
58HAEMOPHILUS INFLUENZAE----[3] 61, 62, 66 💬
59Hiberix[1] Haemophilus influenzae type B strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen---[4] 13, 61, 62, 66 💬
60HIBERIX - POLVERE E SOLVENTE PER SOLUZIONE INIETTABILE PER USO INTRAMUSCOLARE 1 FLACONCINO DI POLVERE + 1 SIRINGA PRERIEMPITA DI SOLVENTE DA 0.5 ML[1] Haemophilus influenzae type B strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen---[3] 61, 62, 66 💬
61Human monoclonal antibody directed against complement 5 protein----[1] 62 💬
62Iptacopan[1] Iptacopan[1] Iptacopan 💬[1] CFB 💬[3] Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection 💬[5] 61, 62, 66, 109, 222 💬
63Iptacopan (LNP023)[1] Iptacopan[1] Iptacopan 💬[1] CFB 💬[3] Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection 💬[1] 62 💬
64Iron Dextran[2] Dextran,
Iron Dextran		[2] Dextran 1 ,
Iron dextran 💬		--[1] 62 💬
65Iron sucrose[3] Iron,
Iron sucrose,
Sucrose		[2] Sucrose ,
Iron sucrose 💬		--[3] 62, 96, 97 💬
66KP104----[3] 49, 62, 66 💬
67L04AA25----[1] 62 💬
68Lapine T-Lymphocyte Immune Globulin[1] Antithymocyte immunoglobulin (rabbit)---[4] 62, 65, 283, 286 💬
69Levamisole[1] Levamisole[1] Levamisole 💬--[4] 60, 61, 62, 222 💬
70Levamisole+cyclosporin A+Glucocorticoids[2] Cyclosporine,
Levamisole		[2] Cyclosporine ,
Levamisole 💬		[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[2] 60, 62 💬
71LFG316----[1] 62 💬
72LNP023----[5] 61, 62, 66, 109, 222 💬
73LNP023 HYDROCHLORIDE SALT----[1] 62 💬
74Melphalan[1] Melphalan[1] Melphalan 💬--[15] 11, 13, 14, 19, 20, 28, 60, 62, 65, 96, 164, 234, 284, 285, 299 💬
75Menveo[9] Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine,
Meningococcal polysaccharide vaccine group A,
Meningococcal polysaccharide vaccine group C,
Meningococcal polysaccharide vaccine group W-135,
Meningococcal polysaccharide vaccine group Y,
Neisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen,
Neisseria meningitidis group c capsular oligosaccharide diphtheria crm197 protein conjugate antigen,
Neisseria meningitidis group w-135 capsular oligosaccharide diphtheria crm197 protein conjugate antigen,
Neisseria meningitidis group y capsular oligosaccharide diphtheria crm197 protein conjugate antigen		[2] Meningococcal polysaccharide vaccine group A ,
Meningococcal polysaccharide vaccine group C 💬		--[6] 11, 13, 61, 62, 66, 222 💬
76MENVEO - POLV.E SOLUZ.PER SOLUZ. INIETT.-USO INTRAMUSCOLARE-COMP. CONIUG.LIOFILIZZ.MENA:FLAC.(VETRO) COMP. GONIUG.LIQUI.MENCWY:FLAC.(VETRO)-1 FLAC+1FLAC[9] Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine,
Meningococcal polysaccharide vaccine group A,
Meningococcal polysaccharide vaccine group C,
Meningococcal polysaccharide vaccine group W-135,
Meningococcal polysaccharide vaccine group Y,
Neisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen,
Neisseria meningitidis group c capsular oligosaccharide diphtheria crm197 protein conjugate antigen,
Neisseria meningitidis group w-135 capsular oligosaccharide diphtheria crm197 protein conjugate antigen,
Neisseria meningitidis group y capsular oligosaccharide diphtheria crm197 protein conjugate antigen		[2] Meningococcal polysaccharide vaccine group A ,
Meningococcal polysaccharide vaccine group C 💬		--[2] 62, 66 💬
77MENVEO – Polvere e soluzione per soluzione iniettabile[9] Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine,
Meningococcal polysaccharide vaccine group A,
Meningococcal polysaccharide vaccine group C,
Meningococcal polysaccharide vaccine group W-135,
Meningococcal polysaccharide vaccine group Y,
Neisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen,
Neisseria meningitidis group c capsular oligosaccharide diphtheria crm197 protein conjugate antigen,
Neisseria meningitidis group w-135 capsular oligosaccharide diphtheria crm197 protein conjugate antigen,
Neisseria meningitidis group y capsular oligosaccharide diphtheria crm197 protein conjugate antigen		[2] Meningococcal polysaccharide vaccine group A ,
Meningococcal polysaccharide vaccine group C 💬		--[2] 61, 62 💬
78Methotrexate[1] Methotrexate[1] Methotrexate 💬[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
79Methylprednisolone[1] Methylprednisolone[1] Methylprednisolone 💬[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[46] 2, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
80MY008211A tablets----[1] 62 💬
81Mycophenolate[1] Mycophenolic acid[1] Mycophenolic acid 💬[2] IMPDH1,
IMPDH2 💬		[4] Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬[36] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
82Mycophenolate mofetil[2] Mycophenolate mofetil,
Mycophenolic acid		[2] Mycophenolate mofetil ,
Mycophenolic acid 💬		[2] IMPDH1,
IMPDH2 💬		[4] Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬[34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
83Myeloablative Preparative Regimen----[3] 62, 65, 284 💬
84NM8074----[2] 62, 109 💬
85NO----[9] 6, 46, 58, 62, 86, 97, 222, 299, 321 💬
86PEGCETACOPLAN[1] Pegcetacoplan[1] Pegcetacoplan 💬[1] C3 💬[17] Alcoholic liver disease, Chagas disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Phagosome, Shigellosis, Staphylococcus aureus infection, Systemic lupus erythematosus, Tuberculosis, Viral carcinogenesis 💬[4] 2, 61, 62, 222 💬
87Pegcetacoplan (APL-2)[1] Pegcetacoplan[1] Pegcetacoplan 💬[1] C3 💬[17] Alcoholic liver disease, Chagas disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Phagosome, Shigellosis, Staphylococcus aureus infection, Systemic lupus erythematosus, Tuberculosis, Viral carcinogenesis 💬[3] 2, 61, 62 💬
88Phosphate[1] Phosphate ion---[32] 2, 3, 6, 11, 12, 13, 28, 36, 46, 49, 51, 53, 60, 62, 65, 70, 78, 81, 83, 90, 96, 97, 164, 235, 238, 256, 276, 283, 284, 285, 286, 299 💬
89PNEUMOVAX – Soluzione iniettabile in siringa preriempita da 0,5 ml----[2] 62, 66 💬
90Pozelimab[1] Pozelimab[1] Pozelimab 💬[1] C5 💬[11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[2] 11, 62 💬
91RA101495----[1] 62 💬
92RA101495 sodium----[1] 62 💬
93RAVULIZUMAB[1] Ravulizumab[1] Ravulizumab 💬[1] C5 💬[11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[7] 2, 11, 13, 50, 62, 66, 109 💬
94Reduced Intensity Preparative Regimen----[3] 62, 65, 284 💬
95Reduced Toxicity Ablative Regimen----[3] 62, 65, 284 💬
96REGN3918----[2] 11, 62 💬
97RO7112689----[1] 62 💬
98RO7112689/F01----[1] 62 💬
99RO7112689/F03-01----[2] 62, 109 💬
100RO7112689/F03-10----[2] 62, 109 💬
101RVA576----[3] 62, 109, 162 💬
102RVA576 (COVERSIN)[1] Nomacopan[1] Nomacopan 💬[1] C5 💬[11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[2] 62, 109 💬
103Sargramostim[1] Sargramostim[1] Sargramostim 💬[1] CSF2RA 💬[4] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬[7] 6, 28, 60, 62, 96, 229, 285 💬
104SB12 (proposed eculizumab biosimilar)[1] Eculizumab[1] Eculizumab 💬[1] C5 💬[11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 62 💬
105Sirolimus[1] Sirolimus[1] Sirolimus 💬[1] MTOR 💬[51] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[35] 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 98, 137, 157, 158, 192, 222, 277, 278, 279, 280, 281, 283, 300, 331 💬
106Solaris----[2] 62, 109 💬
107SOLIRIS[1] Eculizumab[1] Eculizumab 💬[1] C5 💬[11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[7] 11, 13, 14, 61, 62, 109, 222 💬
108Soliris (eculizumab)[1] Eculizumab[1] Eculizumab 💬[1] C5 💬[11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 62 💬
109SOLIRIS - 300 MG CONCENTRATO PER SOLUZIONE PER INFUSIONE - USO ENDOVENOSO 1 FLACONCINO (VETRO) 30 ML (10 MG/ML)[1] Eculizumab[1] Eculizumab 💬[1] C5 💬[11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[3] 13, 62, 109 💬
110Soliris 300[1] Eculizumab[1] Eculizumab 💬[1] C5 💬[11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 62 💬
111Soliris 300 mg concentrate for solution for infusion[1] Eculizumab[1] Eculizumab 💬[1] C5 💬[11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 62 💬
112Soliris 300mg/30ml[1] Eculizumab[1] Eculizumab 💬[1] C5 💬[11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 62 💬
113Soliris ™ (eculizumab)[1] Eculizumab[1] Eculizumab 💬[1] C5 💬[11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 62 💬
114Soliris®[1] Eculizumab[1] Eculizumab 💬[1] C5 💬[11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 62 💬
115SOLIRIS® (eculizumab) injection, for intravenous use[1] Eculizumab[1] Eculizumab 💬[1] C5 💬[11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 62 💬
116Sterile Normal Saline (0.9% NaCl)----[2] 62, 254 💬
117Sucrose[1] Sucrose[1] Sucrose 💬--[3] 62, 96, 97 💬
118Synthetic 15-amino-acid macrocyclic peptide----[1] 62 💬
119Synthetic 15-amino-acid macrocyclic peptide acylated with a ethyleneglycol24----[1] 62 💬
120Synthetic 15-amino-acid macrocyclic peptide acylated with a ethyleneglycol24 palmitoylated linker----[1] 62 💬
121Synthetic 15-amino-acid macrocyclic peptide acylated with a polyethyleneglycol palmitoylated linker----[1] 62 💬
122Systematic chemotherapy and antibodies----[1] 62 💬
123Systemic chemotherapy and antibodies----[2] 62, 326 💬
124Tacrolimus[1] Tacrolimus[2] Tacrolimus ,
Tacrolimus 💬		[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
125TREOSULFAN[1] Treosulfan[1] Treosulfan 💬--[6] 13, 19, 62, 65, 283, 286 💬
126Tretinoin[1] Tretinoin[1] Tretinoin 💬[3] PML,
RARA,
RARB 💬		[12] Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬[3] 2, 62, 75 💬
127Ultomiris[1] Ravulizumab[1] Ravulizumab 💬[1] C5 💬[11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[6] 2, 11, 13, 50, 62, 66 💬
128ULTOMIRIS - 300 MG - CONCENTRATO PER SOLUZIONE PER INFUSIONE - USO ENDOVENOSO - FLACONCINO (VETRO) 3 ML (100 MG / ML) - 1 FLACONCINO[1] Ravulizumab[1] Ravulizumab 💬[1] C5 💬[11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 62 💬
129Ultomiris 300mg/30ml[1] Ravulizumab[1] Ravulizumab 💬[1] C5 💬[11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 62 💬
130ULTOMIRIS ™ (ravulizumab-cwvz)[1] Ravulizumab[1] Ravulizumab 💬[1] C5 💬[11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 62 💬
131VACCINO CONTRO IL MEMINGOCOCCO DI GRUPPO B----[3] 61, 62, 66 💬
132VACCINO HAEMOPHILUS INFLUENZAE B CONIUGATO CON TOSSOIDETETANICO----[2] 61, 62 💬
133VACCINO PNEUMOCOCCICO----[2] 62, 66 💬
134VACCINO POLISACCARIDICO ANTI-MENINGOCOCCICO (A.C.Y E W-135)----[3] 61, 62, 66 💬
135VARI----[2] 62, 274 💬
136Zilucoplan[1] Zilucoplan[1] Zilucoplan 💬[1] C5 💬[11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[3] 2, 11, 62 💬
137Zilucoplan (RA101495)[1] Zilucoplan[1] Zilucoplan 💬[1] C5 💬[11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[2] 11, 62 💬
138 LNP023 HYDROCHLORIDE SALT----[5] 61, 62, 66, 109, 222 💬