Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Alanine 💬 [1] Alanine[2] Alanine; L-alanine; --[4] 6, 13, 298, 299 💬
2 Ascorbic acid 💬 [1] Ascorbic acid[4] Acidum ascorbicum; ASCORBIC ACID; Iron; Vitamin C; --[8] 10, 97, 192, 206, 210, 211, 212, 298 💬
3 Methionine 💬 [1] Methionine[3] Butanoic acid; L-methionine; Methionine; --[6] 34, 84, 93, 229, 298, 300 💬
4 Tyrosine 💬 [1] Tyrosine[4] Alanine; L-Tyrosine; Propanoic acid; Tyrosine; --[4] 6, 86, 111, 298 💬
5 Indomethacin 💬 [1] Indomethacin[2] INDOMETACIN; Indomethacin; [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[3] 225, 271, 298 💬
6 Trimethoprim 💬 [1] Trimethoprim[2] Bactrim; Trimethoprim; --[7] 36, 44, 49, 60, 61, 85, 299 💬
7 Cholecalciferol 💬 [1] Cholecalciferol[5] Cholecalciferol; Colecalciferol; Multivitamin; Vitamin D; Vitamin D3; [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[16] 6, 13, 19, 20, 34, 46, 49, 51, 53, 60, 65, 96, 97, 228, 298, 299 💬
8 Acarbose 💬 [1] Acarbose[1] Acarbose; [5] AMY2A,
AMY2B,
GAA,
GANC,
MGAM 💬		[7] Carbohydrate digestion and absorption, Galactose metabolism, Lysosome, Metabolic pathways, Pancreatic secretion, Salivary secretion, Starch and sucrose metabolism 💬[1] 298 💬
9 Acetylcysteine 💬 [1] Acetylcysteine[3] Acetylcysteine; Mucomyst; N-Acetylcysteine; --[21] 6, 13, 19, 20, 21, 49, 51, 53, 58, 63, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337 💬
10 Diazepam 💬 [1] Diazepam[1] Diazepam; [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[3] 46, 155, 298 💬
11 Dronabinol 💬 [1] Dronabinol[4] DELTA-9-TETRAHYDROCANNABINOL; Dronabinol; Sativex; Tetrahydrocannabinol; [2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[7] 2, 8, 13, 36, 46, 271, 298 💬
12 Gabapentin 💬 [1] Gabapentin[4] Gabapentin; GABAPENTINA; Gabapentine; NEURONTIN; [5] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬		[9] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle 💬[5] 6, 13, 19, 70, 298 💬
13 Triamcinolone 💬 [1] Triamcinolone[4] Kenalog; Naltrexone; TRIAMCINOLONE; TRIAMCINOLONE ACETONIDE; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[11] 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
14 Simvastatin 💬 [1] Simvastatin[3] SIMVASTATIN; Simvastatina; Simvastatine; [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[21] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
15 Omeprazole 💬 [1] Omeprazole[4] Losec; Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM; [2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[14] 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
16 Pentoxifylline 💬 [1] Pentoxifylline[1] Pentoxifylline; --[12] 26, 56, 84, 86, 93, 96, 97, 113, 220, 222, 296, 298 💬
17 Midazolam 💬 [1] Midazolam[2] Midazolam; Midazolam injection; [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
18 Thalidomide 💬 [1] Thalidomide[1] Thalidomide; [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[20] 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
19 Paricalcitol 💬 [1] Paricalcitol[1] Paricalcitol; [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[5] 19, 66, 218, 238, 298 💬
20 Bentiromide 💬 [1] Bentiromide[0] ---
21 Proglumide 💬 [1] Proglumide[1] Proglumide; [1] CCKBR 💬[3] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬[1] 298 💬
22 Magnesium L-aspartate 💬 [1] Magnesium aspartate[1] Magnesium aspartate; --[1] 298 💬
23 Levocarnitine 💬 [1] Levocarnitine[4] Carnitine; L-Carnitine; LEVOCARNITINE; Xyzal; --[11] 3, 5, 13, 53, 58, 86, 96, 97, 265, 298, 316 💬
24 Tocopherol 💬 [1] Tocopherol[2] Tocoferol; Tocopherol; --[6] 13, 49, 90, 206, 257, 298 💬
25 Pregabalin 💬 [1] Pregabalin[2] Lyrica; Pregabalin; [4] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4 💬		[7] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway 💬[5] 13, 36, 46, 70, 298 💬
26 Oxycodone 💬 [1] Oxycodone[2] OXYCODONE; OXYCODONE HYDROCHLORIDE; [3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[5] 6, 13, 70, 226, 298 💬
27 Pancrelipase 💬 [1] Pancrelipase[2] Pancreatin; Pancrelipase; --[2] 298, 299 💬
28 Perflubutane 💬 [1] Perflubutane[1] Perflubutane; --[2] 298, 300 💬
29 Ethanol 💬 [1] Ethanol[3] Alcohol; Ethanol; PREDNISONE; --[5] 58, 97, 279, 280, 298 💬
30 Lacosamide 💬 [1] Lacosamide[1] Lacosamide; [2] SCN3A,
SCN9A 💬		[1] Taste transduction 💬[4] 2, 46, 149, 298 💬
31 Amlodipine 💬 [1] Amlodipine[1] AMLODIPINE; [4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 51, 67, 298 💬
32 Bupivacaine 💬 [1] Bupivacaine[2] Bupivacaine; BUPIVACAINE HYDROCHLORIDE; [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[8] 46, 51, 53, 70, 96, 168, 226, 298 💬
33 Esomeprazole 💬 [1] Esomeprazole[3] Esomeprazole; Nexium; Omeprazole; [2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[8] 13, 46, 86, 98, 107, 113, 298, 299 💬
34 Hydroxychloroquine 💬 [1] Hydroxychloroquine[3] Hydroxychloroquine; Hydroxychloroquine sulfate; PLAQUENIL; --[27] 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299 💬
35 Pioglitazone 💬 [1] Pioglitazone[1] Pioglitazone; [1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
36 Sulfanilamide 💬 [1] Sulfanilamide[0] ---
37 Reparixin 💬 [1] Reparixin[1] Reparixin; [2] CXCR1,
CXCR2 💬		[7] Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, Human cytomegalovirus infection, Phospholipase D signaling pathway, Viral protein interaction with cytokine and cytokine receptor 💬[2] 298, 299 💬
38 Tanezumab 💬 [1] Tanezumab[1] Tanezumab; [1] NGF 💬[9] Apoptosis, Calcium signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬[2] 226, 298 💬