Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 CDK4 [6] PI3K-Akt signaling pathway, Tight junction, T cell receptor signaling pathway, Pathways in cancer, Viral carcinogenesis, Small cell lung cancer D10688 Abemaciclib [1] 34
2 CDK6 [4] PI3K-Akt signaling pathway, Pathways in cancer, Viral carcinogenesis, Small cell lung cancer D10688 Abemaciclib [1] 34
3 CSF1R [6] Ras signaling pathway, Rap1 signaling pathway, Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Pathways in cancer, Transcriptional misregulation in cancer D08552 Sunitinib [2] 28, 34
4 CSF1R [6] Ras signaling pathway, Rap1 signaling pathway, Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Pathways in cancer, Transcriptional misregulation in cancer D11270 Pexidartinib [1] 34
5 CSF2RA [1] Pathways in cancer D05066 Molgramostim [3] 97, 229, 299
6 CSF2RA [1] Pathways in cancer D05712 Regramostim [1] 229
7 CSF2RA [1] Pathways in cancer D05803 Sargramostim [7] 6, 28, 60, 62, 96, 229, 285
8 CSF2RA [1] Pathways in cancer D09930 Mavrilimumab [2] 41, 46
9 CSF3R [2] PI3K-Akt signaling pathway, Pathways in cancer D03235 Filgrastim [35] 2, 6, 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331
10 CSF3R [2] PI3K-Akt signaling pathway, Pathways in cancer D03247 Lenograstim [7] 2, 13, 16, 18, 19, 57, 65
11 CSF3R [2] PI3K-Akt signaling pathway, Pathways in cancer D06889 Pegfilgrastim [1] 60
12 NQO1 [2] Ubiquinone and other terpenoid-quinone biosynthesis, Pathways in cancer D08682 Warfarin [11] 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91
13 AGTR1 [5] Phospholipase D signaling pathway, Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion, Pathways in cancer D00150 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224
14 AGTR1 [5] Phospholipase D signaling pathway, Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion, Pathways in cancer D00400 Valsartan [7] 57, 58, 66, 75, 218, 222, 224
15 AGTR1 [5] Phospholipase D signaling pathway, Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion, Pathways in cancer D00522 Candesartan [2] 58, 67
16 AGTR1 [5] Phospholipase D signaling pathway, Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion, Pathways in cancer D00523 Irbesartan [4] 66, 167, 168, 222
17 AGTR1 [5] Phospholipase D signaling pathway, Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion, Pathways in cancer D00626 Candesartan cilexetil [1] 67
18 AGTR1 [5] Phospholipase D signaling pathway, Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion, Pathways in cancer D00627 Telmisartan [2] 66, 67
19 AGTR1 [5] Phospholipase D signaling pathway, Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion, Pathways in cancer D02014 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224
20 AGTR1 [5] Phospholipase D signaling pathway, Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion, Pathways in cancer D08146 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
21 AGTR1 [5] Phospholipase D signaling pathway, Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion, Pathways in cancer D11776 Sparsentan [3] 66, 218, 222
22 EDNRA [3] Vascular smooth muscle contraction, Renin secretion, Pathways in cancer D01227 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
23 EDNRA [3] Vascular smooth muscle contraction, Renin secretion, Pathways in cancer D07077 Ambrisentan [7] 51, 84, 85, 86, 88, 210, 211
24 EDNRA [3] Vascular smooth muscle contraction, Renin secretion, Pathways in cancer D07171 Sitaxentan [1] 86
25 EDNRA [3] Vascular smooth muscle contraction, Renin secretion, Pathways in cancer D07538 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
26 EDNRA [3] Vascular smooth muscle contraction, Renin secretion, Pathways in cancer D07741 Zibotentan [1] 51
27 EDNRA [3] Vascular smooth muscle contraction, Renin secretion, Pathways in cancer D10135 Macitentan [5] 51, 85, 86, 88, 210
28 EDNRA [3] Vascular smooth muscle contraction, Renin secretion, Pathways in cancer D11776 Sparsentan [3] 66, 218, 222
29 EDNRB [2] Relaxin signaling pathway, Pathways in cancer D01227 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
30 EDNRB [2] Relaxin signaling pathway, Pathways in cancer D07538 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
31 EDNRB [2] Relaxin signaling pathway, Pathways in cancer D10135 Macitentan [5] 51, 85, 86, 88, 210
32 EGFR [11] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Pathways in cancer, Proteoglycans in cancer, Prostate cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D01977 Gefitinib [1] 75
33 EGFR [11] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Pathways in cancer, Proteoglycans in cancer, Prostate cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D03455 Cetuximab [2] 51, 86
34 EGFR [11] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Pathways in cancer, Proteoglycans in cancer, Prostate cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D07907 Erlotinib [1] 94
35 EGFR [11] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Pathways in cancer, Proteoglycans in cancer, Prostate cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D08108 Lapatinib [3] 34, 74, 75
36 EGFR [11] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Pathways in cancer, Proteoglycans in cancer, Prostate cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D08950 Neratinib [1] 34
37 EGFR [11] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Pathways in cancer, Proteoglycans in cancer, Prostate cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D11251 Icotinib [1] 34
38 EGFR [11] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Pathways in cancer, Proteoglycans in cancer, Prostate cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D11772 Tesevatinib [1] 67
39 EPOR [2] PI3K-Akt signaling pathway, Pathways in cancer D09946 Peginesatide [1] 283
40 ERBB2 [6] Platinum drug resistance, PI3K-Akt signaling pathway, Tight junction, Pathways in cancer, Proteoglycans in cancer, Prostate cancer D08108 Lapatinib [3] 34, 74, 75
41 ERBB2 [6] Platinum drug resistance, PI3K-Akt signaling pathway, Tight junction, Pathways in cancer, Proteoglycans in cancer, Prostate cancer D08950 Neratinib [1] 34
42 ERBB2 [6] Platinum drug resistance, PI3K-Akt signaling pathway, Tight junction, Pathways in cancer, Proteoglycans in cancer, Prostate cancer D11772 Tesevatinib [1] 67
43 ESR1 [4] Prolactin signaling pathway, Thyroid hormone signaling pathway, Pathways in cancer, Proteoglycans in cancer D00105 Estradiol [7] 13, 46, 49, 65, 76, 226, 299
44 ESR1 [4] Prolactin signaling pathway, Thyroid hormone signaling pathway, Pathways in cancer, Proteoglycans in cancer D00185 Estriol [2] 13, 227
45 ESR1 [4] Prolactin signaling pathway, Thyroid hormone signaling pathway, Pathways in cancer, Proteoglycans in cancer D00289 Danazol [5] 60, 63, 64, 65, 285
46 ESR1 [4] Prolactin signaling pathway, Thyroid hormone signaling pathway, Pathways in cancer, Proteoglycans in cancer D00554 Ethinylestradiol [4] 13, 46, 49, 299
47 ESR1 [4] Prolactin signaling pathway, Thyroid hormone signaling pathway, Pathways in cancer, Proteoglycans in cancer D00575 Mestranol [2] 46, 49
48 ESR1 [4] Prolactin signaling pathway, Thyroid hormone signaling pathway, Pathways in cancer, Proteoglycans in cancer D01161 Fulvestrant [2] 49, 86
49 ESR1 [4] Prolactin signaling pathway, Thyroid hormone signaling pathway, Pathways in cancer, Proteoglycans in cancer D01413 Estradiol valerate [1] 65
50 ESR1 [4] Prolactin signaling pathway, Thyroid hormone signaling pathway, Pathways in cancer, Proteoglycans in cancer D01986 Estriol [2] 13, 227
51 ESR1 [4] Prolactin signaling pathway, Thyroid hormone signaling pathway, Pathways in cancer, Proteoglycans in cancer D02367 Desogestrel [1] 230
52 ESR1 [4] Prolactin signaling pathway, Thyroid hormone signaling pathway, Pathways in cancer, Proteoglycans in cancer D07726 Clomifene [1] 74
53 ESR1 [4] Prolactin signaling pathway, Thyroid hormone signaling pathway, Pathways in cancer, Proteoglycans in cancer D08409 Prasterone [6] 49, 53, 83, 86, 96, 113
54 ESR1 [4] Prolactin signaling pathway, Thyroid hormone signaling pathway, Pathways in cancer, Proteoglycans in cancer D08465 Raloxifene [1] 46
55 ESR1 [4] Prolactin signaling pathway, Thyroid hormone signaling pathway, Pathways in cancer, Proteoglycans in cancer D08559 Tamoxifen [3] 2, 113, 227
56 ESR1 [4] Prolactin signaling pathway, Thyroid hormone signaling pathway, Pathways in cancer, Proteoglycans in cancer D11513 Estetrol [1] 53
57 ESR1 [4] Prolactin signaling pathway, Thyroid hormone signaling pathway, Pathways in cancer, Proteoglycans in cancer D11514 Estetrol [1] 53
58 ESR2 [2] Prolactin signaling pathway, Pathways in cancer D00105 Estradiol [7] 13, 46, 49, 65, 76, 226, 299
59 ESR2 [2] Prolactin signaling pathway, Pathways in cancer D00185 Estriol [2] 13, 227
60 ESR2 [2] Prolactin signaling pathway, Pathways in cancer D00575 Mestranol [2] 46, 49
61 ESR2 [2] Prolactin signaling pathway, Pathways in cancer D01161 Fulvestrant [2] 49, 86
62 ESR2 [2] Prolactin signaling pathway, Pathways in cancer D01413 Estradiol valerate [1] 65
63 ESR2 [2] Prolactin signaling pathway, Pathways in cancer D01986 Estriol [2] 13, 227
64 ESR2 [2] Prolactin signaling pathway, Pathways in cancer D07726 Clomifene [1] 74
65 ESR2 [2] Prolactin signaling pathway, Pathways in cancer D08409 Prasterone [6] 49, 53, 83, 86, 96, 113
66 ESR2 [2] Prolactin signaling pathway, Pathways in cancer D08465 Raloxifene [1] 46
67 ESR2 [2] Prolactin signaling pathway, Pathways in cancer D08559 Tamoxifen [3] 2, 113, 227
68 ESR2 [2] Prolactin signaling pathway, Pathways in cancer D11513 Estetrol [1] 53
69 ESR2 [2] Prolactin signaling pathway, Pathways in cancer D11514 Estetrol [1] 53
70 F2 [4] Phospholipase D signaling pathway, Platelet activation, Regulation of actin cytoskeleton, Pathways in cancer D06410 Thrombomodulin Alfa [1] 85
71 F2 [4] Phospholipase D signaling pathway, Platelet activation, Regulation of actin cytoskeleton, Pathways in cancer D07144 Dabigatran etexilate [2] 51, 75
72 F2 [4] Phospholipase D signaling pathway, Platelet activation, Regulation of actin cytoskeleton, Pathways in cancer D09707 Dabigatran [5] 51, 75, 85, 91, 124
73 FGFR1 [9] Ras signaling pathway, Rap1 signaling pathway, PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Regulation of actin cytoskeleton, Pathways in cancer, Proteoglycans in cancer, Prostate cancer D10481 Nintedanib [5] 51, 85, 89, 227, 228
74 FGFR1 [9] Ras signaling pathway, Rap1 signaling pathway, PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Regulation of actin cytoskeleton, Pathways in cancer, Proteoglycans in cancer, Prostate cancer D11589 Infigratinib [1] 276
75 FGFR3 [6] Ras signaling pathway, Rap1 signaling pathway, PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton, Pathways in cancer D10481 Nintedanib [5] 51, 85, 89, 227, 228
76 FGFR3 [6] Ras signaling pathway, Rap1 signaling pathway, PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton, Pathways in cancer D11589 Infigratinib [1] 276
77 FGFR2 [7] Ras signaling pathway, Rap1 signaling pathway, PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton, Pathways in cancer, Prostate cancer D05338 Palifermin [5] 13, 36, 38, 39, 65
78 FGFR2 [7] Ras signaling pathway, Rap1 signaling pathway, PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton, Pathways in cancer, Prostate cancer D10481 Nintedanib [5] 51, 85, 89, 227, 228
79 FGFR2 [7] Ras signaling pathway, Rap1 signaling pathway, PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton, Pathways in cancer, Prostate cancer D11589 Infigratinib [1] 276
80 FLT3 [4] Ras signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Transcriptional misregulation in cancer D08524 Sorafenib [2] 34, 86
81 FLT3 [4] Ras signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Transcriptional misregulation in cancer D08552 Sunitinib [2] 28, 34
82 FLT3 [4] Ras signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Transcriptional misregulation in cancer D11270 Pexidartinib [1] 34
83 FLT4 [4] Ras signaling pathway, Rap1 signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer D03218 Axitinib [1] 34
84 FLT4 [4] Ras signaling pathway, Rap1 signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer D08524 Sorafenib [2] 34, 86
85 FLT4 [4] Ras signaling pathway, Rap1 signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer D08552 Sunitinib [2] 28, 34
86 FLT4 [4] Ras signaling pathway, Rap1 signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer D08881 Cediranib [1] 34
87 FLT4 [4] Ras signaling pathway, Rap1 signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer D10481 Nintedanib [5] 51, 85, 89, 227, 228
88 FLT4 [4] Ras signaling pathway, Rap1 signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer D11772 Tesevatinib [1] 67
89 ALK [2] Pathways in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D09731 Crizotinib [1] 34
90 ALK [2] Pathways in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D10866 Brigatinib [1] 34
91 MTOR [13] Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Shigellosis, Pathways in cancer, Proteoglycans in cancer, Prostate cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D00753 Sirolimus [40] 2, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331
92 MTOR [13] Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Shigellosis, Pathways in cancer, Proteoglycans in cancer, Prostate cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D02714 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277
93 MTOR [13] Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Shigellosis, Pathways in cancer, Proteoglycans in cancer, Prostate cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D06068 Temsirolimus [1] 13
94 ABL1 [3] Ras signaling pathway, Pathways in cancer, Viral myocarditis D03252 Bosutinib [2] 2, 67
95 ABL1 [3] Ras signaling pathway, Pathways in cancer, Viral myocarditis D03658 Dasatinib [2] 51, 85
96 ABL1 [3] Ras signaling pathway, Pathways in cancer, Viral myocarditis D06414 Dasatinib [2] 51, 85
97 ABL1 [3] Ras signaling pathway, Pathways in cancer, Viral myocarditis D08066 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
98 ABL1 [3] Ras signaling pathway, Pathways in cancer, Viral myocarditis D08953 Nilotinib [5] 6, 8, 34, 51, 86
99 ABL1 [3] Ras signaling pathway, Pathways in cancer, Viral myocarditis D09664 Saracatinib [3] 6, 89, 272
100 HDAC1 [4] Thyroid hormone signaling pathway, Pathways in cancer, Transcriptional misregulation in cancer, Viral carcinogenesis D06320 Vorinostat [2] 75, 96
101 HDAC2 [4] Thyroid hormone signaling pathway, Pathways in cancer, Transcriptional misregulation in cancer, Viral carcinogenesis D06320 Vorinostat [2] 75, 96
102 HMOX1 [2] Porphyrin metabolism, Pathways in cancer D05922 Stannsoporfin [1] 254
103 IFNA1 [5] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis, Pathways in cancer D09662 Rontalizumab [1] 49
104 IFNA1 [5] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis, Pathways in cancer D09668 Sifalimumab [1] 49
105 IFNA2 [5] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis, Pathways in cancer D09662 Rontalizumab [1] 49
106 IFNA2 [5] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis, Pathways in cancer D09668 Sifalimumab [1] 49
107 IFNA4 [5] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis, Pathways in cancer D09662 Rontalizumab [1] 49
108 IFNA4 [5] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis, Pathways in cancer D09668 Sifalimumab [1] 49
109 IFNA5 [5] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis, Pathways in cancer D09662 Rontalizumab [1] 49
110 IFNA5 [5] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis, Pathways in cancer D09668 Sifalimumab [1] 49
111 IFNA6 [5] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis, Pathways in cancer D09662 Rontalizumab [1] 49
112 IFNA6 [5] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis, Pathways in cancer D09668 Sifalimumab [1] 49
113 IFNA7 [5] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis, Pathways in cancer D09662 Rontalizumab [1] 49
114 IFNA7 [5] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis, Pathways in cancer D09668 Sifalimumab [1] 49
115 IFNA8 [5] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis, Pathways in cancer D09662 Rontalizumab [1] 49
116 IFNA8 [5] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis, Pathways in cancer D09668 Sifalimumab [1] 49
117 IFNA10 [5] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis, Pathways in cancer D09662 Rontalizumab [1] 49
118 IFNA10 [5] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis, Pathways in cancer D09668 Sifalimumab [1] 49
119 IFNA13 [5] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis, Pathways in cancer D09662 Rontalizumab [1] 49
120 IFNA13 [5] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis, Pathways in cancer D09668 Sifalimumab [1] 49
121 IFNA14 [5] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis, Pathways in cancer D09662 Rontalizumab [1] 49
122 IFNA14 [5] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis, Pathways in cancer D09668 Sifalimumab [1] 49
123 IFNA16 [5] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis, Pathways in cancer D09662 Rontalizumab [1] 49
124 IFNA16 [5] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis, Pathways in cancer D09668 Sifalimumab [1] 49
125 IFNA17 [5] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis, Pathways in cancer D09662 Rontalizumab [1] 49
126 IFNA17 [5] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis, Pathways in cancer D09668 Sifalimumab [1] 49
127 IFNA21 [5] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis, Pathways in cancer D09662 Rontalizumab [1] 49
128 IFNA21 [5] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Tuberculosis, Pathways in cancer D09668 Sifalimumab [1] 49
129 IFNAR1 [3] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, Pathways in cancer D00745 Interferon alfa-2a [1] 56
130 IFNAR1 [3] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, Pathways in cancer D00746 Interferon beta-1b [1] 13
131 IFNAR1 [3] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, Pathways in cancer D02745 Interferon alfa-2b [2] 25, 34
132 IFNAR1 [3] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, Pathways in cancer D03305 Interferon alfa [6] 13, 25, 26, 28, 56, 96
133 IFNAR1 [3] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, Pathways in cancer D04554 Interferon beta-1a [4] 13, 26, 96, 97
134 IFNAR1 [3] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, Pathways in cancer D10483 Peginterferon beta-1a [1] 13
135 IFNAR1 [3] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, Pathways in cancer D11082 Anifrolumab [3] 46, 49, 53
136 IFNAR2 [3] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, Pathways in cancer D00745 Interferon alfa-2a [1] 56
137 IFNAR2 [3] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, Pathways in cancer D00746 Interferon beta-1b [1] 13
138 IFNAR2 [3] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, Pathways in cancer D02745 Interferon alfa-2b [2] 25, 34
139 IFNAR2 [3] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, Pathways in cancer D03305 Interferon alfa [6] 13, 25, 26, 28, 56, 96
140 IFNAR2 [3] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, Pathways in cancer D04554 Interferon beta-1a [4] 13, 26, 96, 97
141 IFNAR2 [3] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, Pathways in cancer D10483 Peginterferon beta-1a [1] 13
142 IFNAR2 [3] PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, Pathways in cancer D11082 Anifrolumab [3] 46, 49, 53
143 IFNG [12] Proteasome, TGF-beta signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Pathways in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D04242 Fontolizumab [1] 46
144 IFNG [12] Proteasome, TGF-beta signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Pathways in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D11120 Emapalumab [3] 49, 65, 107
145 IFNGR1 [6] Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Pathways in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D00747 Interferon gamma-1b [7] 18, 65, 85, 228, 299, 301, 326
146 IFNGR2 [6] Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Pathways in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D00747 Interferon gamma-1b [7] 18, 65, 85, 228, 299, 301, 326
147 IGF1R [9] Ras signaling pathway, Rap1 signaling pathway, PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Progesterone-mediated oocyte maturation, Pathways in cancer, Transcriptional misregulation in cancer, Proteoglycans in cancer, Prostate cancer D03297 Mecasermin [6] 65, 78, 96, 168, 265, 299
148 IGF1R [9] Ras signaling pathway, Rap1 signaling pathway, PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Progesterone-mediated oocyte maturation, Pathways in cancer, Transcriptional misregulation in cancer, Proteoglycans in cancer, Prostate cancer D09680 Teprotumumab [1] 51
149 IGF1R [9] Ras signaling pathway, Rap1 signaling pathway, PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Progesterone-mediated oocyte maturation, Pathways in cancer, Transcriptional misregulation in cancer, Proteoglycans in cancer, Prostate cancer D09925 Linsitinib [1] 232
150 IL2RA [5] Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Pathways in cancer D00748 Aldesleukin [6] 2, 35, 49, 65, 96, 97
151 IL2RA [5] Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Pathways in cancer D03058 Basiliximab [6] 2, 50, 66, 97, 222, 228
152 IL2RA [5] Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Pathways in cancer D03639 Daclizumab [8] 13, 56, 60, 65, 97, 107, 283, 284
153 IL2RB [6] Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Pathways in cancer, Transcriptional misregulation in cancer D00748 Aldesleukin [6] 2, 35, 49, 65, 96, 97
154 IL2RG [6] Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Pathways in cancer, Primary immunodeficiency D00748 Aldesleukin [6] 2, 35, 49, 65, 96, 97
155 IL4 [5] PI3K-Akt signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Pathways in cancer D03117 Binetrakin [1] 46
156 IL4R [4] PI3K-Akt signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Pathways in cancer D10354 Dupilumab [5] 51, 97, 98, 160, 162
157 IL5 [3] Th1 and Th2 cell differentiation, T cell receptor signaling pathway, Pathways in cancer D04923 Mepolizumab [4] 44, 45, 98, 162
158 IL5 [3] Th1 and Th2 cell differentiation, T cell receptor signaling pathway, Pathways in cancer D08985 Reslizumab [2] 44, 98
159 IL5RA [1] Pathways in cancer D09874 Benralizumab [5] 44, 45, 98, 162, 299
160 IL6 [14] Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, Th17 cell differentiation, TNF signaling pathway, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Pertussis, Yersinia infection, Tuberculosis, Pathways in cancer, Transcriptional misregulation in cancer, Rheumatoid arthritis D01583 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
161 IL6 [14] Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, Th17 cell differentiation, TNF signaling pathway, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Pertussis, Yersinia infection, Tuberculosis, Pathways in cancer, Transcriptional misregulation in cancer, Rheumatoid arthritis D08976 Pomalidomide [5] 28, 51, 85, 227, 331
162 IL6 [14] Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, Th17 cell differentiation, TNF signaling pathway, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Pertussis, Yersinia infection, Tuberculosis, Pathways in cancer, Transcriptional misregulation in cancer, Rheumatoid arthritis D09669 Siltuximab [2] 28, 331
163 IL6 [14] Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, Th17 cell differentiation, TNF signaling pathway, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Pertussis, Yersinia infection, Tuberculosis, Pathways in cancer, Transcriptional misregulation in cancer, Rheumatoid arthritis D10080 Sirukumab [2] 41, 46
164 IL6 [14] Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, Th17 cell differentiation, TNF signaling pathway, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Pertussis, Yersinia infection, Tuberculosis, Pathways in cancer, Transcriptional misregulation in cancer, Rheumatoid arthritis D12487 Olokizumab [2] 46, 96
165 IL6R [4] Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Th17 cell differentiation, Pathways in cancer D02596 Tocilizumab [21] 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331
166 IL6R [4] Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Th17 cell differentiation, Pathways in cancer D10161 Sarilumab [5] 41, 46, 84, 107, 271
167 IL6R [4] Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Th17 cell differentiation, Pathways in cancer D11079 Satralizumab [3] 11, 13, 86
168 IL12A [8] Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Type I diabetes mellitus, Pertussis, Toxoplasmosis, Tuberculosis, Pathways in cancer D09214 Ustekinumab [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271
169 IL12B [9] Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Type I diabetes mellitus, Pertussis, Toxoplasmosis, Tuberculosis, Pathways in cancer, Proteoglycans in cancer D09214 Ustekinumab [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271
170 IL13 [2] Th1 and Th2 cell differentiation, Pathways in cancer D08857 Anrukinzumab [1] 97
171 IL13 [2] Th1 and Th2 cell differentiation, Pathways in cancer D09633 Lebrikizumab [1] 85
172 IL13 [2] Th1 and Th2 cell differentiation, Pathways in cancer D09979 Tralokinumab [2] 85, 97
173 AR [2] Pathways in cancer, Prostate cancer D00075 Testosterone [8] 1, 2, 3, 13, 60, 76, 78, 113
174 AR [2] Pathways in cancer, Prostate cancer D00289 Danazol [5] 60, 63, 64, 65, 285
175 AR [2] Pathways in cancer, Prostate cancer D00444 Stanozolol [1] 60
176 AR [2] Pathways in cancer, Prostate cancer D00462 Oxandrolone [2] 211, 285
177 AR [2] Pathways in cancer, Prostate cancer D00586 Flutamide [1] 81
178 AR [2] Pathways in cancer, Prostate cancer D00955 Nandrolone decanoate [2] 60, 85
179 AR [2] Pathways in cancer, Prostate cancer D00958 Testosterone enanthate [1] 113
180 AR [2] Pathways in cancer, Prostate cancer D00959 Testosterone propionate [1] 113
181 AR [2] Pathways in cancer, Prostate cancer D03338 Calusterone [1] 2
182 AR [2] Pathways in cancer, Prostate cancer D06087 Testosterone undecanoate [2] 13, 60
183 AR [2] Pathways in cancer, Prostate cancer D08250 Nandrolone [2] 60, 85
184 AR [2] Pathways in cancer, Prostate cancer D08409 Prasterone [6] 49, 53, 83, 86, 96, 113
185 AR [2] Pathways in cancer, Prostate cancer D08573 Testosterone decanoate [1] 113
186 AR [2] Pathways in cancer, Prostate cancer D08574 Testosterone phenylpropionate [1] 113
187 JAK1 [9] PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Pathways in cancer, Viral carcinogenesis, PD-L1 expression and PD-1 checkpoint pathway in cancer D09959 Ruxolitinib [3] 60, 65, 228
188 JAK1 [9] PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Pathways in cancer, Viral carcinogenesis, PD-L1 expression and PD-1 checkpoint pathway in cancer D09970 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300
189 JAK1 [9] PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Pathways in cancer, Viral carcinogenesis, PD-L1 expression and PD-1 checkpoint pathway in cancer D10308 Baricitinib [13] 2, 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325
190 JAK1 [9] PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Pathways in cancer, Viral carcinogenesis, PD-L1 expression and PD-1 checkpoint pathway in cancer D10653 Peficitinib [1] 46
191 JAK1 [9] PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Pathways in cancer, Viral carcinogenesis, PD-L1 expression and PD-1 checkpoint pathway in cancer D10871 Filgotinib [6] 46, 53, 96, 97, 222, 271
192 JAK1 [9] PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Pathways in cancer, Viral carcinogenesis, PD-L1 expression and PD-1 checkpoint pathway in cancer D10944 Itacitinib [4] 46, 51, 97, 228
193 JAK1 [9] PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Pathways in cancer, Viral carcinogenesis, PD-L1 expression and PD-1 checkpoint pathway in cancer D10994 Upadacitinib [8] 40, 41, 46, 49, 96, 97, 107, 271
194 JAK1 [9] PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Pathways in cancer, Viral carcinogenesis, PD-L1 expression and PD-1 checkpoint pathway in cancer D11400 Abrocitinib [1] 84
195 JAK2 [9] PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Prolactin signaling pathway, Toxoplasmosis, Tuberculosis, Pathways in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D09959 Ruxolitinib [3] 60, 65, 228
196 JAK2 [9] PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Prolactin signaling pathway, Toxoplasmosis, Tuberculosis, Pathways in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D09970 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300
197 JAK2 [9] PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Prolactin signaling pathway, Toxoplasmosis, Tuberculosis, Pathways in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D10308 Baricitinib [13] 2, 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325
198 JAK2 [9] PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Prolactin signaling pathway, Toxoplasmosis, Tuberculosis, Pathways in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D10653 Peficitinib [1] 46
199 JAK3 [7] PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Pathways in cancer, Viral carcinogenesis, Primary immunodeficiency D09970 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300
200 JAK3 [7] PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Pathways in cancer, Viral carcinogenesis, Primary immunodeficiency D10653 Peficitinib [1] 46
201 KIT [5] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer D03658 Dasatinib [2] 51, 85
202 KIT [5] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer D06414 Dasatinib [2] 51, 85
203 KIT [5] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer D08066 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
204 KIT [5] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer D08524 Sorafenib [2] 34, 86
205 KIT [5] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer D08552 Sunitinib [2] 28, 34
206 KIT [5] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer D08953 Nilotinib [5] 6, 8, 34, 51, 86
207 KIT [5] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer D10229 Masitinib [6] 2, 5, 6, 13, 46, 96
208 KIT [5] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer D11270 Pexidartinib [1] 34
209 MET [7] Ras signaling pathway, Rap1 signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Transcriptional misregulation in cancer, Proteoglycans in cancer, Renal cell carcinoma D10062 Cabozantinib [1] 34
210 NFE2L2 [2] Protein processing in endoplasmic reticulum, Pathways in cancer D10964 Omaveloxolone [1] 18
211 NFKB1 [24] Ras signaling pathway, Sphingolipid signaling pathway, PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Prolactin signaling pathway, Relaxin signaling pathway, Pathways of neurodegeneration - multiple diseases, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Pathways in cancer, Transcriptional misregulation in cancer, Viral carcinogenesis, Prostate cancer, Small cell lung cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D01146 Iguratimod [5] 46, 51, 53, 271, 300
212 IL23A [5] Th17 cell differentiation, Pertussis, Tuberculosis, Pathways in cancer, Rheumatoid arthritis D09214 Ustekinumab [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271
213 IL23A [5] Th17 cell differentiation, Pertussis, Tuberculosis, Pathways in cancer, Rheumatoid arthritis D10400 Tildrakizumab [2] 162, 271
214 IL23A [5] Th17 cell differentiation, Pertussis, Tuberculosis, Pathways in cancer, Rheumatoid arthritis D10438 Guselkumab [5] 37, 41, 51, 96, 97
215 IL23A [5] Th17 cell differentiation, Pertussis, Tuberculosis, Pathways in cancer, Rheumatoid arthritis D10912 Brazikumab [2] 96, 97
216 IL23A [5] Th17 cell differentiation, Pertussis, Tuberculosis, Pathways in cancer, Rheumatoid arthritis D11052 Risankizumab [4] 37, 96, 97, 271
217 IL23A [5] Th17 cell differentiation, Pertussis, Tuberculosis, Pathways in cancer, Rheumatoid arthritis D11123 Mirikizumab [3] 37, 96, 97
218 PDGFRA [7] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Pathways in cancer, Prostate cancer D08066 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
219 PDGFRA [7] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Pathways in cancer, Prostate cancer D08552 Sunitinib [2] 28, 34
220 PDGFRA [7] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Pathways in cancer, Prostate cancer D08953 Nilotinib [5] 6, 8, 34, 51, 86
221 PDGFRA [7] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Pathways in cancer, Prostate cancer D10481 Nintedanib [5] 51, 85, 89, 227, 228
222 PDGFRB [7] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Pathways in cancer, Prostate cancer D03658 Dasatinib [2] 51, 85
223 PDGFRB [7] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Pathways in cancer, Prostate cancer D06414 Dasatinib [2] 51, 85
224 PDGFRB [7] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Pathways in cancer, Prostate cancer D08524 Sorafenib [2] 34, 86
225 PDGFRB [7] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Pathways in cancer, Prostate cancer D08552 Sunitinib [2] 28, 34
226 PDGFRB [7] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Pathways in cancer, Prostate cancer D08953 Nilotinib [5] 6, 8, 34, 51, 86
227 PDGFRB [7] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Pathways in cancer, Prostate cancer D10481 Nintedanib [5] 51, 85, 89, 227, 228
228 PGF [4] Ras signaling pathway, Rap1 signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer D09574 Aflibercept [2] 90, 166
229 PIK3CA [32] Platinum drug resistance, Ras signaling pathway, Rap1 signaling pathway, Phosphatidylinositol signaling system, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Prion disease, Shigellosis, Salmonella infection, Yersinia infection, Pathways in cancer, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D11011 Alpelisib [1] 138
230 PIK3CA [32] Platinum drug resistance, Ras signaling pathway, Rap1 signaling pathway, Phosphatidylinositol signaling system, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Prion disease, Shigellosis, Salmonella infection, Yersinia infection, Pathways in cancer, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D11158 Leniolisib [2] 53, 65
231 PIK3CB [32] Platinum drug resistance, Ras signaling pathway, Rap1 signaling pathway, Phosphatidylinositol signaling system, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Prion disease, Shigellosis, Salmonella infection, Yersinia infection, Pathways in cancer, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D11158 Leniolisib [2] 53, 65
232 PIK3CD [32] Platinum drug resistance, Ras signaling pathway, Rap1 signaling pathway, Phosphatidylinositol signaling system, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Prion disease, Shigellosis, Salmonella infection, Yersinia infection, Pathways in cancer, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D11158 Leniolisib [2] 53, 65
233 PIK3CD [32] Platinum drug resistance, Ras signaling pathway, Rap1 signaling pathway, Phosphatidylinositol signaling system, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Prion disease, Shigellosis, Salmonella infection, Yersinia infection, Pathways in cancer, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D11437 Parsaclisib [3] 35, 53, 61
234 PML [3] Ubiquitin mediated proteolysis, Pathways in cancer, Transcriptional misregulation in cancer D00094 Tretinoin [6] 2, 62, 63, 75, 94, 231
235 PPARG [5] PPAR signaling pathway, Thermogenesis, Pathways in cancer, Transcriptional misregulation in cancer, Thyroid cancer D08378 Pioglitazone [17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
236 PPARG [5] PPAR signaling pathway, Thermogenesis, Pathways in cancer, Transcriptional misregulation in cancer, Thyroid cancer D08491 Rosiglitazone [5] 46, 75, 97, 222, 265
237 PPARG [5] PPAR signaling pathway, Thermogenesis, Pathways in cancer, Transcriptional misregulation in cancer, Thyroid cancer D11256 Seladelpar [2] 93, 94
238 PPARG [5] PPAR signaling pathway, Thermogenesis, Pathways in cancer, Transcriptional misregulation in cancer, Thyroid cancer D11603 Leriglitazone [1] 20
239 PPARG [5] PPAR signaling pathway, Thermogenesis, Pathways in cancer, Transcriptional misregulation in cancer, Thyroid cancer D12242 Bocidelpar [1] 113
240 PRKCB [16] Ras signaling pathway, Rap1 signaling pathway, Phosphatidylinositol signaling system, Sphingolipid signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway, VEGF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Salivary secretion, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Proteoglycans in cancer D11935 Enzastaurin [1] 168
241 MAP2K1 [26] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Pathways in cancer, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D09666 Selumetinib [1] 34
242 MAP2K1 [26] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Pathways in cancer, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D10175 Trametinib [4] 2, 34, 279, 280
243 MAP2K1 [26] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Pathways in cancer, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D10405 Cobimetinib [1] 280
244 MAP2K1 [26] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Pathways in cancer, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D10604 Binimetinib [1] 34
245 MAP2K1 [26] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Pathways in cancer, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D11675 Mirdametinib [1] 34
246 MAP2K2 [23] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Pathways in cancer, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D09666 Selumetinib [1] 34
247 MAP2K2 [23] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Pathways in cancer, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D10175 Trametinib [4] 2, 34, 279, 280
248 MAP2K2 [23] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Pathways in cancer, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D10405 Cobimetinib [1] 280
249 MAP2K2 [23] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Pathways in cancer, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D10604 Binimetinib [1] 34
250 MAP2K2 [23] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Pathways in cancer, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D11675 Mirdametinib [1] 34
251 PTGER1 [1] Pathways in cancer D00180 Alprostadil [2] 51, 70
252 PTGER1 [1] Pathways in cancer D02722 Limaprost [1] 70
253 PTGER2 [2] Renin secretion, Pathways in cancer D00419 Misoprostol [3] 46, 70, 271
254 PTGER3 [2] Regulation of lipolysis in adipocytes, Pathways in cancer D00419 Misoprostol [3] 46, 70, 271
255 PTGER4 [2] Renin secretion, Pathways in cancer D00419 Misoprostol [3] 46, 70, 271
256 PTGS2 [8] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D00109 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251
257 PTGS2 [8] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D00118 Naproxen [4] 13, 46, 107, 271
258 PTGS2 [8] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D00120 Sulindac [1] 206
259 PTGS2 [8] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D00126 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299
260 PTGS2 [8] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D00130 Diflunisal [1] 28
261 PTGS2 [8] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D00132 Ketoprofen [1] 46
262 PTGS2 [8] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D00141 Indomethacin [3] 225, 271, 298
263 PTGS2 [8] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D00217 Acetaminophen [15] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337
264 PTGS2 [8] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D00315 Etodolac [1] 46
265 PTGS2 [8] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D00330 Flurbiprofen [3] 13, 21, 46
266 PTGS2 [8] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D00428 Salsalate [1] 5
267 PTGS2 [8] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D00567 Celecoxib [10] 2, 3, 34, 46, 70, 89, 107, 161, 171, 271
268 PTGS2 [8] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D00568 Rofecoxib [1] 46
269 PTGS2 [8] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D00969 Meloxicam [4] 46, 49, 271, 296
270 PTGS2 [8] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D01049 Nimesulide [1] 46
271 PTGS2 [8] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D01183 Tolfenamic acid [1] 5
272 PTGS2 [8] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D01545 Aceclofenac [1] 46
273 PTGS2 [8] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D02709 Valdecoxib [1] 46
274 PTGS2 [8] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D03710 Etoricoxib [2] 46, 271
275 PTGS2 [8] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D03714 Lumiracoxib [1] 46
276 PTGS2 [8] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D03716 Parecoxib [2] 46, 271
277 PTGS2 [8] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D07816 Diclofenac [5] 13, 34, 46, 78, 271
278 PTGS2 [8] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D08104 Ketorolac [2] 70, 226
279 PTGS2 [8] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D08149 Loxoprofen [2] 46, 271
280 RAF1 [23] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, T cell receptor signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Tuberculosis, Pathways in cancer, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D08524 Sorafenib [2] 34, 86
281 RARA [3] Th17 cell differentiation, Pathways in cancer, Transcriptional misregulation in cancer D00094 Tretinoin [6] 2, 62, 63, 75, 94, 231
282 RARA [3] Th17 cell differentiation, Pathways in cancer, Transcriptional misregulation in cancer D00348 Isotretinoin [4] 36, 39, 159, 160
283 RARA [3] Th17 cell differentiation, Pathways in cancer, Transcriptional misregulation in cancer D01418 Tamibarotene [2] 26, 96
284 RARA [3] Th17 cell differentiation, Pathways in cancer, Transcriptional misregulation in cancer D02754 Acitretin [1] 37
285 RARA [3] Th17 cell differentiation, Pathways in cancer, Transcriptional misregulation in cancer D02815 Alitretinoin [1] 49
286 RARA [3] Th17 cell differentiation, Pathways in cancer, Transcriptional misregulation in cancer D04162 Fenretinide [1] 299
287 RARA [3] Th17 cell differentiation, Pathways in cancer, Transcriptional misregulation in cancer D06543 Vitamin A [3] 13, 53, 90
288 RARB [2] Pathways in cancer, Small cell lung cancer D00094 Tretinoin [6] 2, 62, 63, 75, 94, 231
289 RARB [2] Pathways in cancer, Small cell lung cancer D00348 Isotretinoin [4] 36, 39, 159, 160
290 RARB [2] Pathways in cancer, Small cell lung cancer D02754 Acitretin [1] 37
291 RARB [2] Pathways in cancer, Small cell lung cancer D02815 Alitretinoin [1] 49
292 RARB [2] Pathways in cancer, Small cell lung cancer D04162 Fenretinide [1] 299
293 RARB [2] Pathways in cancer, Small cell lung cancer D06543 Vitamin A [3] 13, 53, 90
294 BCL2 [12] Platinum drug resistance, Sphingolipid signaling pathway, Protein processing in endoplasmic reticulum, PI3K-Akt signaling pathway, Pathways of neurodegeneration - multiple diseases, Shigellosis, Salmonella infection, Toxoplasmosis, Tuberculosis, Pathways in cancer, Prostate cancer, Small cell lung cancer D10679 Venetoclax [1] 28
295 RELA [24] Ras signaling pathway, Sphingolipid signaling pathway, PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Prolactin signaling pathway, Relaxin signaling pathway, Pathways of neurodegeneration - multiple diseases, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Pathways in cancer, Transcriptional misregulation in cancer, Viral carcinogenesis, Prostate cancer, Small cell lung cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D12181 Edasalonexent [1] 113
296 RET [2] Pathways in cancer, Thyroid cancer D08524 Sorafenib [2] 34, 86
297 RET [2] Pathways in cancer, Thyroid cancer D08552 Sunitinib [2] 28, 34
298 ROCK1 [10] Sphingolipid signaling pathway, Vascular smooth muscle contraction, TGF-beta signaling pathway, Tight junction, Platelet activation, Regulation of actin cytoskeleton, Shigellosis, Yersinia infection, Pathways in cancer, Proteoglycans in cancer D07941 Fasudil [4] 2, 5, 7, 51
299 RXRA [8] PPAR signaling pathway, PI3K-Akt signaling pathway, Th17 cell differentiation, Thyroid hormone signaling pathway, Pathways in cancer, Transcriptional misregulation in cancer, Thyroid cancer, Small cell lung cancer D02754 Acitretin [1] 37
300 RXRA [8] PPAR signaling pathway, PI3K-Akt signaling pathway, Th17 cell differentiation, Thyroid hormone signaling pathway, Pathways in cancer, Transcriptional misregulation in cancer, Thyroid cancer, Small cell lung cancer D02815 Alitretinoin [1] 49
301 RXRA [8] PPAR signaling pathway, PI3K-Akt signaling pathway, Th17 cell differentiation, Thyroid hormone signaling pathway, Pathways in cancer, Transcriptional misregulation in cancer, Thyroid cancer, Small cell lung cancer D03106 Bexarotene [2] 13, 75
302 RXRB [7] PPAR signaling pathway, Th17 cell differentiation, Thyroid hormone signaling pathway, Pathways in cancer, Transcriptional misregulation in cancer, Thyroid cancer, Small cell lung cancer D02754 Acitretin [1] 37
303 RXRB [7] PPAR signaling pathway, Th17 cell differentiation, Thyroid hormone signaling pathway, Pathways in cancer, Transcriptional misregulation in cancer, Thyroid cancer, Small cell lung cancer D02815 Alitretinoin [1] 49
304 RXRB [7] PPAR signaling pathway, Th17 cell differentiation, Thyroid hormone signaling pathway, Pathways in cancer, Transcriptional misregulation in cancer, Thyroid cancer, Small cell lung cancer D03106 Bexarotene [2] 13, 75
305 RXRG [7] PPAR signaling pathway, Th17 cell differentiation, Thyroid hormone signaling pathway, Pathways in cancer, Transcriptional misregulation in cancer, Thyroid cancer, Small cell lung cancer D02754 Acitretin [1] 37
306 RXRG [7] PPAR signaling pathway, Th17 cell differentiation, Thyroid hormone signaling pathway, Pathways in cancer, Transcriptional misregulation in cancer, Thyroid cancer, Small cell lung cancer D02815 Alitretinoin [1] 49
307 RXRG [7] PPAR signaling pathway, Th17 cell differentiation, Thyroid hormone signaling pathway, Pathways in cancer, Transcriptional misregulation in cancer, Thyroid cancer, Small cell lung cancer D03106 Bexarotene [2] 13, 75
308 SMO [2] Pathways in cancer, Proteoglycans in cancer D09992 Vismodegib [1] 85
309 SMO [2] Pathways in cancer, Proteoglycans in cancer D10671 Taladegib [1] 85
310 BRAF [11] Rap1 signaling pathway, Vascular smooth muscle contraction, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D08524 Sorafenib [2] 34, 86
311 BRAF [11] Rap1 signaling pathway, Vascular smooth muscle contraction, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D10064 Dabrafenib [1] 34
312 TGFB1 [9] TGF-beta signaling pathway, Th17 cell differentiation, Relaxin signaling pathway, Toxoplasmosis, Tuberculosis, Pathways in cancer, Proteoglycans in cancer, Renal cell carcinoma, Rheumatoid arthritis D09620 Fresolimumab [3] 51, 85, 222
313 TGFB2 [7] TGF-beta signaling pathway, Toxoplasmosis, Tuberculosis, Pathways in cancer, Proteoglycans in cancer, Renal cell carcinoma, Rheumatoid arthritis D09620 Fresolimumab [3] 51, 85, 222
314 TGFB3 [6] TGF-beta signaling pathway, Toxoplasmosis, Tuberculosis, Pathways in cancer, Renal cell carcinoma, Rheumatoid arthritis D09620 Fresolimumab [3] 51, 85, 222
315 VEGFA [9] Ras signaling pathway, Rap1 signaling pathway, PI3K-Akt signaling pathway, VEGF signaling pathway, Relaxin signaling pathway, Pathways in cancer, Proteoglycans in cancer, Renal cell carcinoma, Rheumatoid arthritis D05697 Ranibizumab [4] 34, 166, 227, 301
316 VEGFA [9] Ras signaling pathway, Rap1 signaling pathway, PI3K-Akt signaling pathway, VEGF signaling pathway, Relaxin signaling pathway, Pathways in cancer, Proteoglycans in cancer, Renal cell carcinoma, Rheumatoid arthritis D06409 Bevacizumab [6] 13, 34, 85, 87, 227, 280
317 VEGFA [9] Ras signaling pathway, Rap1 signaling pathway, PI3K-Akt signaling pathway, VEGF signaling pathway, Relaxin signaling pathway, Pathways in cancer, Proteoglycans in cancer, Renal cell carcinoma, Rheumatoid arthritis D09574 Aflibercept [2] 90, 166
318 VEGFB [5] Ras signaling pathway, Rap1 signaling pathway, PI3K-Akt signaling pathway, Relaxin signaling pathway, Pathways in cancer D09574 Aflibercept [2] 90, 166
319 CXCR4 [5] Viral life cycle - HIV-1, Virion - Human immunodeficiency virus, Viral protein interaction with cytokine and cytokine receptor, Regulation of actin cytoskeleton, Pathways in cancer D08971 Plerixafor [5] 19, 20, 65, 285, 299
320 FGF23 [5] Ras signaling pathway, Rap1 signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Pathways in cancer D10913 Burosumab [1] 238
321 CASP9 [12] Platinum drug resistance, PI3K-Akt signaling pathway, VEGF signaling pathway, Thyroid hormone signaling pathway, Prion disease, Pathways of neurodegeneration - multiple diseases, Toxoplasmosis, Tuberculosis, Pathways in cancer, Prostate cancer, Small cell lung cancer, Viral myocarditis D11195 Rimiducid [6] 19, 60, 65, 284, 285, 326
322 ROCK2 [11] Sphingolipid signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway, Tight junction, Platelet activation, Regulation of actin cytoskeleton, Shigellosis, Salmonella infection, Yersinia infection, Pathways in cancer, Proteoglycans in cancer D07941 Fasudil [4] 2, 5, 7, 51
323 ROCK2 [11] Sphingolipid signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway, Tight junction, Platelet activation, Regulation of actin cytoskeleton, Shigellosis, Salmonella infection, Yersinia infection, Pathways in cancer, Proteoglycans in cancer D11815 Belumosudil [2] 51, 85
324 KEAP1 [2] Ubiquitin mediated proteolysis, Pathways in cancer D03846 Dimethyl fumarate [5] 13, 49, 51, 86, 296