Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 SLC6A1 💬 2件: Synaptic vesicle cycle, GABAergic synapse Gabapentin 💬 Gabapentin 5件: 6, 13, 19, 70, 298 💬
2 SLC6A2 💬 1件: Synaptic vesicle cycle Amoxapine 💬 Amoxapine 1件: 46 💬
3 SLC6A2 💬 1件: Synaptic vesicle cycle Methylphenidate 💬 Methylphenidate 7件: 6, 13, 34, 84, 113, 179, 206 💬
4 SLC6A2 💬 1件: Synaptic vesicle cycle Phentermine 💬 Phentermine 1件: 97 💬
5 SLC6A2 💬 1件: Synaptic vesicle cycle Amitriptyline 💬 Amitriptyline 4件: 78, 97, 226, 299 💬
6 SLC6A2 💬 1件: Synaptic vesicle cycle Atomoxetine 💬 Atomoxetine 4件: 6, 8, 13, 17 💬
7 SLC6A2 💬 1件: Synaptic vesicle cycle Bupropion 💬 Bupropion 5件: 8, 18, 21, 96, 171 💬
8 SLC6A2 💬 1件: Synaptic vesicle cycle Desipramine 💬 Desipramine 2件: 120, 156 💬
9 SLC6A2 💬 1件: Synaptic vesicle cycle Doxepin 💬 Doxepin 1件: 6 💬
10 SLC6A2 💬 1件: Synaptic vesicle cycle Duloxetine 💬 Duloxetine 2件: 6, 13 💬
11 SLC6A2 💬 1件: Synaptic vesicle cycle Lisdexamfetamine 💬 Lisdexamfetamine 1件: 13 💬
12 SLC6A2 💬 1件: Synaptic vesicle cycle Milnacipran 💬 Milnacipran 2件: 46, 49 💬
13 SLC6A2 💬 1件: Synaptic vesicle cycle Nortriptyline 💬 Nortriptyline 2件: 6, 226 💬
14 SLC6A2 💬 1件: Synaptic vesicle cycle Venlafaxine 💬 Venlafaxine 3件: 6, 13, 46 💬
15 SLC6A2 💬 1件: Synaptic vesicle cycle Ampreloxetine 💬 Ampreloxetine 2件: 6, 17 💬
16 SLC6A3 💬 7件: Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Armodafinil 💬 Armodafinil 3件: 6, 13, 84 💬
17 SLC6A3 💬 7件: Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Methylphenidate 💬 Methylphenidate 7件: 6, 13, 34, 84, 113, 179, 206 💬
18 SLC6A3 💬 7件: Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Phentermine 💬 Phentermine 1件: 97 💬
19 SLC6A3 💬 7件: Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Bupropion 💬 Bupropion 5件: 8, 18, 21, 96, 171 💬
20 SLC6A3 💬 7件: Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Lisdexamfetamine 💬 Lisdexamfetamine 1件: 13 💬
21 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Amoxapine 💬 Amoxapine 1件: 46 💬
22 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Fluoxetine 💬 Fluoxetine 6件: 13, 17, 78, 86, 179, 206 💬
23 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Sertraline 💬 Sertraline 2件: 6, 206 💬
24 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Paroxetine 💬 Paroxetine 4件: 6, 13, 46, 85 💬
25 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Phentermine 💬 Phentermine 1件: 97 💬
26 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Amitriptyline 💬 Amitriptyline 4件: 78, 97, 226, 299 💬
27 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Citalopram 💬 Citalopram 7件: 6, 8, 13, 18, 46, 98, 127 💬
28 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Desipramine 💬 Desipramine 2件: 120, 156 💬
29 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Doxepin 💬 Doxepin 1件: 6 💬
30 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Duloxetine 💬 Duloxetine 2件: 6, 13 💬
31 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Escitalopram 💬 Escitalopram 4件: 2, 6, 13, 46 💬
32 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Fenfluramine 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
33 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Milnacipran 💬 Milnacipran 2件: 46, 49 💬
34 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Nortriptyline 💬 Nortriptyline 2件: 6, 226 💬
35 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Trazodone 💬 Trazodone 1件: 2 💬
36 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Venlafaxine 💬 Venlafaxine 3件: 6, 13, 46 💬
37 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Vortioxetine 💬 Vortioxetine 1件: 6 💬
38 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Ampreloxetine 💬 Ampreloxetine 2件: 6, 17 💬
39 SLC18A2 💬 7件: Synaptic vesicle cycle, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Tetrabenazine 💬 Tetrabenazine 1件: 8 💬
40 SLC18A2 💬 7件: Synaptic vesicle cycle, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Valbenazine 💬 Valbenazine 1件: 8 💬
41 SLC18A2 💬 7件: Synaptic vesicle cycle, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Deutetrabenazine 💬 Deutetrabenazine 1件: 8 💬
42 SNAP25 💬 2件: Synaptic vesicle cycle, Insulin secretion Botulinum toxin type A 💬 Botulinum toxin type A 14件: 2, 5, 6, 7, 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬
43 SNAP25 💬 2件: Synaptic vesicle cycle, Insulin secretion Rimabotulinumtoxin B 💬 Botulinum toxin type B 4件: 2, 6, 13, 51 💬
44 CACNA1B 💬 15件: MAPK signaling pathway, Calcium signaling pathway, Synaptic vesicle cycle, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Type II diabetes mellitus, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Morphine addiction, Nicotine addiction, Chemical carcinogenesis - receptor activation Cilnidipine 💬 Cilnidipine 1件: 67 💬