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 Target Gene/Pathway(薬物標的遺伝子/パスウェイリスト) 

   e.g. "Sirolimus", "アダリムマブ", "MAP2K"    Synonyms (Drugs) were also searched for.

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166 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY
 On map, Yellow: Drug target, Red: Disease-related 
 KEGG GENES  KEGG DRUG  DrugBank   指定難病告示番号
 1  Adipocytokine signaling pathway 
 3 genes, 7 drugs (DrugBank) and 40 diseases shown 
 1件: JAK2   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 1件: PRKCQ   D09671   Sotrastaurin   1件: 97 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 2  Adrenergic signaling in cardiomyocytes 
 6 genes, 3 drugs (DrugBank) and 27 diseases shown 
 1件: AGTR1   D00357   Losartan   18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4   D00332   Gabapentin   7件: 6, 13, 19, 70, 97, 226, 298 
 1件: SCN5A   D00358   Lidocaine   10件: 6, 13, 46, 84, 86, 97, 168, 226, 231, 256 
 D02086 
 D08127 
 3  African trypanosomiasis 
 3 genes, 6 drugs (DrugBank) and 41 diseases shown 
 2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 4  AGE-RAGE signaling pathway in diabetic complications 
 5 genes, 8 drugs (DrugBank) and 50 diseases shown 
 1件: AGTR1   D00357   Losartan   18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 1件: JAK2   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 2件: PRKCD, PRKCE   D09671   Sotrastaurin   1件: 97 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 5  Alcoholism 
 8 genes, 3 drugs (DrugBank) and 9 diseases shown 
 1件: ADORA2A   D00528   Caffeine   6件: 2, 6, 46, 78, 96, 97 
 D01453 
 2件: DRD1, DRD2   D01044   Flupentixol   1件: 97 
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   D00848   Dextromethorphan   9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 
 D03742 
 D03744 
 6  Aldosterone synthesis and secretion 
 3 genes, 3 drugs (DrugBank) and 21 diseases shown 
 1件: AGTR1   D00357   Losartan   18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 1件: PDE2A   D00528   Caffeine   6件: 2, 6, 46, 78, 96, 97 
 D01453 
 1件: PRKCE   D09671   Sotrastaurin   1件: 97 
 7  Allograft rejection 
 5 genes, 7 drugs (DrugBank) and 49 diseases shown 
 2件: CD80, CD86   D03203   Abatacept   24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 8  Alzheimer disease 
 11 genes, 8 drugs (DrugBank) and 72 diseases shown 
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   D00848   Dextromethorphan   9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 
 D03742 
 D03744 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 9  Amoebiasis 
 3 genes, 6 drugs (DrugBank) and 41 diseases shown 
 2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 10  Amphetamine addiction 
 11 genes, 4 drugs (DrugBank) and 59 diseases shown 
 1件: DRD1   D01044   Flupentixol   1件: 97 
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   D00848   Dextromethorphan   9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 
 D03742 
 D03744 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 11  AMPK signaling pathway 
 1 gene, 1 drug (DrugBank) and 5 diseases shown 
 1件: PPARG   D00596   Rosiglitazone   5件: 46, 75, 97, 222, 265 
 D08491 
 12  Amyotrophic lateral sclerosis (ALS) 
 11 genes, 8 drugs (DrugBank) and 72 diseases shown 
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   D00848   Dextromethorphan   9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 
 D03742 
 D03744 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 13  Antifolate resistance 
 3 genes, 6 drugs (DrugBank) and 53 diseases shown 
 2件: DHFR, DHFR2   D00142   Methotrexate   33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 
 D02115 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 14  Antigen processing and presentation 
 1 gene, 5 drugs (DrugBank) and 39 diseases shown 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 15  Apelin signaling pathway 
 3 genes, 3 drugs (DrugBank) and 21 diseases shown 
 1件: AGTR1   D00357   Losartan   18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 1件: PDE3B   D00528   Caffeine   6件: 2, 6, 46, 78, 96, 97 
 D01453 
 1件: PRKCE   D09671   Sotrastaurin   1件: 97 
 16  Apoptosis 
 1 gene, 5 drugs (DrugBank) and 39 diseases shown 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 17  Arrhythmogenic right ventricular cardiomyopathy (ARVC) 
 6 genes, 3 drugs (DrugBank) and 8 diseases shown 
 4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4   D00332   Gabapentin   7件: 6, 13, 19, 70, 97, 226, 298 
 2件: ITGA4, ITGB7   D08083   Vedolizumab   2件: 96, 97 
 1件: ITGB7   D09901   Etrolizumab   2件: 96, 97 
 18  Asthma 
 2 genes, 7 drugs (DrugBank) and 39 diseases shown 
 1件: IL13   D08857   Anrukinzumab   1件: 97 
 D09979   Tralokinumab   2件: 85, 97 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 19  Autoimmune thyroid disease 
 2 genes, 1 drug (DrugBank) and 24 diseases shown 
 2件: CD80, CD86   D03203   Abatacept   24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 20  Autophagy - animal 
 2 genes, 1 drug (DrugBank) and 1 disease shown 
 2件: PRKCD, PRKCQ   D09671   Sotrastaurin   1件: 97 
 21  Axon guidance 
 5 genes, 2 drugs (DrugBank) and 55 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 22  B cell receptor signaling pathway 
 5 genes, 2 drugs (DrugBank) and 55 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 23  Bile secretion 
 1 gene, 1 drug (DrugBank) and 12 diseases shown 
 1件: NR1H4   D00734   Ursodeoxycholic acid   12件: 6, 8, 20, 67, 84, 93, 94, 95, 96, 97, 234, 299 
 24  C-type lectin receptor signaling pathway 
 10 genes, 12 drugs (DrugBank) and 69 diseases shown 
 3件: IL12A, IL12B, IL23A   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL23A   D10438   Guselkumab   3件: 37, 96, 97 
 D11123   Mirikizumab   2件: 96, 97 
 D11052   Risankizumab   4件: 37, 96, 97, 271 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 1件: PRKCD   D09671   Sotrastaurin   1件: 97 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 25  Caffeine metabolism 
 1 gene, 1 drug (DrugBank) and 6 diseases shown 
 1件: XDH   D00224   Allopurinol   6件: 6, 46, 57, 66, 96, 97 
 26  Calcium signaling pathway 
 13 genes, 6 drugs (DrugBank) and 65 diseases shown 
 2件: ADORA2A, PDE1B   D00528   Caffeine   6件: 2, 6, 46, 78, 96, 97 
 D01453 
 1件: AGTR1   D00357   Losartan   18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 1件: DRD1   D01044   Flupentixol   1件: 97 
 4件: GRIN1, GRIN2A, GRIN2C, GRIN2D   D00848   Dextromethorphan   9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 
 D03742 
 D03744 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 27  cAMP signaling pathway 
 15 genes, 4 drugs (DrugBank) and 12 diseases shown 
 8件: ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D   D00528   Caffeine   6件: 2, 6, 46, 78, 96, 97 
 D01453 
 2件: DRD1, DRD2   D01044   Flupentixol   1件: 97 
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   D00848   Dextromethorphan   9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 
 D03742 
 D03744 
 4件: PDE4A, PDE4B, PDE4C, PDE4D   D08860   Apremilast   5件: 46, 50, 56, 97, 271 
 28  Cardiac muscle contraction 
 4 genes, 1 drug (DrugBank) and 7 diseases shown 
 4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4   D00332   Gabapentin   7件: 6, 13, 19, 70, 97, 226, 298 
 29  Cell adhesion molecules (CAMs) 
 5 genes, 4 drugs (DrugBank) and 25 diseases shown 
 2件: CD80, CD86   D03203   Abatacept   24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 2件: ITGA4, ITGB7   D08083   Vedolizumab   2件: 96, 97 
 1件: ITGB7   D09901   Etrolizumab   2件: 96, 97 
 1件: PDCD1   D10316   Nivolumab   10件: 13, 26, 41, 46, 49, 50, 51, 53, 96, 97 
 30  Cellular senescence 
 5 genes, 2 drugs (DrugBank) and 55 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 31  cGMP-PKG signaling pathway 
 13 genes, 7 drugs (DrugBank) and 66 diseases shown 
 5件: ADORA1, PDE2A, PDE3A, PDE3B, PDE5A   D00528   Caffeine   6件: 2, 6, 46, 78, 96, 97 
 D01453 
 1件: AGTR1   D00357   Losartan   18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 1件: OPRD1   D00729   Loperamide   2件: 13, 97 
 D07113 
 D08144 
 D02095   Naltrexone   11件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97 
 D05113 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 1件: PRKCE   D09671   Sotrastaurin   1件: 97 
 32  Chagas disease (American trypanosomiasis) 
 6 genes, 8 drugs (DrugBank) and 42 diseases shown 
 3件: CD3D, CD3E, CD3G   D05092   Muromonab   3件: 60, 96, 97 
 D06314   Visilizumab   2件: 96, 97 
 2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 33  Chemokine signaling pathway 
 3 genes, 2 drugs (DrugBank) and 9 diseases shown 
 2件: JAK2, JAK3   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 1件: PRKCD   D09671   Sotrastaurin   1件: 97 
 34  Cholinergic synapse 
 1 gene, 1 drug (DrugBank) and 9 diseases shown 
 1件: JAK2   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 35  Circadian entrainment 
 7 genes, 2 drugs (DrugBank) and 13 diseases shown 
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   D00848   Dextromethorphan   9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 
 D03742 
 D03744 
 2件: MTNR1A, MTNR1B   D08170   Melatonin   8件: 6, 13, 46, 49, 90, 97, 144, 202 
 36  Cocaine addiction 
 7 genes, 2 drugs (DrugBank) and 9 diseases shown 
 2件: DRD1, DRD2   D01044   Flupentixol   1件: 97 
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   D00848   Dextromethorphan   9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 
 D03742 
 D03744 
 37  Collecting duct acid secretion 
 2 genes, 1 drug (DrugBank) and 15 diseases shown 
 2件: ATP4A, ATP4B   D00455   Omeprazole   15件: 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 
 D01207 
 D05259 
 D05261 
 38  Complement and coagulation cascades 
 2 genes, 2 drugs (DrugBank) and 2 diseases shown 
 1件: F10   D03213   Apixaban   2件: 96, 97 
 1件: SERPINC1   D07510   Parnaparin   1件: 97 
 39  Cortisol synthesis and secretion 
 1 gene, 1 drug (DrugBank) and 18 diseases shown 
 1件: AGTR1   D00357   Losartan   18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 40  Cushing syndrome 
 1 gene, 1 drug (DrugBank) and 18 diseases shown 
 1件: AGTR1   D00357   Losartan   18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 41  Cytokine-cytokine receptor interaction 
 13 genes, 17 drugs (DrugBank) and 48 diseases shown 
 2件: IFNAR1, IFNAR2   D04554   Interferon beta-1a   5件: 13, 14, 26, 96, 97 
 3件: IL12A, IL12B, IL23A   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL13   D08857   Anrukinzumab   1件: 97 
 D09979   Tralokinumab   2件: 85, 97 
 2件: IL17A, IL17F   D11550   Bimekizumab   3件: 46, 97, 271 
 1件: IL23A   D10438   Guselkumab   3件: 37, 96, 97 
 D11123   Mirikizumab   2件: 96, 97 
 D11052   Risankizumab   4件: 37, 96, 97, 271 
 1件: IL2RA   D03058   Basiliximab   7件: 2, 50, 65, 66, 97, 222, 228 
 D03639   Daclizumab   7件: 13, 56, 60, 65, 97, 283, 284 
 3件: IL2RA, IL2RB, IL2RG   D00748   Aldesleukin   4件: 2, 49, 65, 97 
 1件: LTB   D08866   Baminercept   4件: 13, 46, 53, 97 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 42  Dilated cardiomyopathy (DCM) 
 7 genes, 8 drugs (DrugBank) and 42 diseases shown 
 4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4   D00332   Gabapentin   7件: 6, 13, 19, 70, 97, 226, 298 
 2件: ITGA4, ITGB7   D08083   Vedolizumab   2件: 96, 97 
 1件: ITGB7   D09901   Etrolizumab   2件: 96, 97 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 43  Dopaminergic synapse 
 8 genes, 5 drugs (DrugBank) and 63 diseases shown 
 2件: DRD1, DRD2   D01044   Flupentixol   1件: 97 
 2件: GRIN2A, GRIN2B   D00848   Dextromethorphan   9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 
 D03742 
 D03744 
 3件: PPP3CA, PPP3CB, PPP3CC   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 1件: SCN1A   D00358   Lidocaine   10件: 6, 13, 46, 84, 86, 97, 168, 226, 231, 256 
 D02086 
 D08127 
 44  Drug metabolism - other enzymes 
 2 genes, 2 drugs (DrugBank) and 9 diseases shown 
 1件: HPRT1   D00161   Mercaptopurine   5件: 86, 94, 96, 97, 164 
 D04931 
 1件: XDH   D00224   Allopurinol   6件: 6, 46, 57, 66, 96, 97 
 45  ECM-receptor interaction 
 2 genes, 2 drugs (DrugBank) and 2 diseases shown 
 2件: ITGA4, ITGB7   D08083   Vedolizumab   2件: 96, 97 
 1件: ITGB7   D09901   Etrolizumab   2件: 96, 97 
 46  EGFR tyrosine kinase inhibitor resistance 
 2 genes, 4 drugs (DrugBank) and 14 diseases shown 
 1件: JAK1   D10871   Filgotinib   6件: 46, 53, 96, 97, 222, 271 
 D10944   Itacitinib   4件: 46, 60, 97, 228 
 D10994   Upadacitinib   6件: 41, 46, 49, 96, 97, 271 
 2件: JAK1, JAK2   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 47  Endocrine and other factor-regulated calcium reabsorption 
 1 gene, 2 drugs (DrugBank) and 16 diseases shown 
 1件: VDR   D00188   Cholecalciferol   15件: 6, 13, 19, 20, 34, 46, 49, 53, 60, 65, 96, 97, 228, 298, 299 
 D00187   Ergocalciferol   5件: 46, 84, 96, 97, 299 
 48  Endocytosis 
 3 genes, 3 drugs (DrugBank) and 13 diseases shown 
 1件: IL2RA   D03058   Basiliximab   7件: 2, 50, 65, 66, 97, 222, 228 
 D03639   Daclizumab   7件: 13, 56, 60, 65, 97, 283, 284 
 3件: IL2RA, IL2RB, IL2RG   D00748   Aldesleukin   4件: 2, 49, 65, 97 
 49  Epstein-Barr virus infection 
 9 genes, 12 drugs (DrugBank) and 45 diseases shown 
 3件: CD3D, CD3E, CD3G   D05092   Muromonab   3件: 60, 96, 97 
 D06314   Visilizumab   2件: 96, 97 
 2件: IFNAR1, IFNAR2   D04554   Interferon beta-1a   5件: 13, 14, 26, 96, 97 
 1件: JAK1   D10871   Filgotinib   6件: 46, 53, 96, 97, 222, 271 
 D10944   Itacitinib   4件: 46, 60, 97, 228 
 D10994   Upadacitinib   6件: 41, 46, 49, 96, 97, 271 
 3件: JAK1, JAK3, TYK2   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 50  Estrogen signaling pathway 
 2 genes, 3 drugs (DrugBank) and 11 diseases shown 
 1件: OPRM1   D00729   Loperamide   2件: 13, 97 
 D07113 
 D08144 
 D02095   Naltrexone   11件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97 
 D05113 
 1件: PRKCD   D09671   Sotrastaurin   1件: 97 
 51  Fc epsilon RI signaling pathway 
 2 genes, 7 drugs (DrugBank) and 39 diseases shown 
 1件: IL13   D08857   Anrukinzumab   1件: 97 
 D09979   Tralokinumab   2件: 85, 97 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 52  Fc gamma R-mediated phagocytosis 
 2 genes, 1 drug (DrugBank) and 1 disease shown 
 2件: PRKCD, PRKCE   D09671   Sotrastaurin   1件: 97 
 53  Fluid shear stress and atherosclerosis 
 1 gene, 5 drugs (DrugBank) and 39 diseases shown 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 54  Focal adhesion 
 2 genes, 2 drugs (DrugBank) and 2 diseases shown 
 2件: ITGA4, ITGB7   D08083   Vedolizumab   2件: 96, 97 
 1件: ITGB7   D09901   Etrolizumab   2件: 96, 97 
 55  Folate biosynthesis 
 4 genes, 2 drugs (DrugBank) and 33 diseases shown 
 2件: DHFR, DHFR2   D00142   Methotrexate   33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 
 D02115 
 2件: TPH1, TPH2   D09973   Telotristat   1件: 97 
 56  FoxO signaling pathway 
 2 genes, 2 drugs (DrugBank) and 3 diseases shown 
 2件: S1PR1, S1PR4   D10930   Etrasimod   1件: 97 
 D10968   Ozanimod   3件: 13, 96, 97 
 57  GABAergic synapse 
 17 genes, 2 drugs (DrugBank) and 12 diseases shown 
 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00550   Midazolam   10件: 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 
 D00696 
 D05028 
 1件: SLC6A1   D00332   Gabapentin   7件: 6, 13, 19, 70, 97, 226, 298 
 58  Gap junction 
 2 genes, 1 drug (DrugBank) and 1 disease shown 
 2件: DRD1, DRD2   D01044   Flupentixol   1件: 97 
 59  Gastric acid secretion 
 2 genes, 1 drug (DrugBank) and 15 diseases shown 
 2件: ATP4A, ATP4B   D00455   Omeprazole   15件: 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 
 D01207 
 D05259 
 D05261 
 60  Glucagon signaling pathway 
 6 genes, 3 drugs (DrugBank) and 57 diseases shown 
 1件: PDE3B   D00528   Caffeine   6件: 2, 6, 46, 78, 96, 97 
 D01453 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 61  Glutamatergic synapse 
 10 genes, 3 drugs (DrugBank) and 59 diseases shown 
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   D00848   Dextromethorphan   9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 
 D03742 
 D03744 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 62  GnRH signaling pathway 
 1 gene, 1 drug (DrugBank) and 1 disease shown 
 1件: PRKCD   D09671   Sotrastaurin   1件: 97 
 63  Graft-versus-host disease 
 3 genes, 6 drugs (DrugBank) and 49 diseases shown 
 2件: CD80, CD86   D03203   Abatacept   24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 64  Growth hormone synthesis, secretion and action 
 1 gene, 1 drug (DrugBank) and 9 diseases shown 
 1件: JAK2   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 65  Hematopoietic cell lineage 
 7 genes, 12 drugs (DrugBank) and 63 diseases shown 
 3件: CD3D, CD3E, CD3G   D05092   Muromonab   3件: 60, 96, 97 
 D06314   Visilizumab   2件: 96, 97 
 1件: IL2RA   D00748   Aldesleukin   4件: 2, 49, 65, 97 
 D03058   Basiliximab   7件: 2, 50, 65, 66, 97, 222, 228 
 D03639   Daclizumab   7件: 13, 56, 60, 65, 97, 283, 284 
 1件: ITGA4   D08083   Vedolizumab   2件: 96, 97 
 1件: MS4A1   D02994   Rituximab   42件: 11, 13, 14, 17, 35, 36, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 223, 229, 256, 271, 283, 284, 285, 288, 300, 331 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 66  Hepatitis B 
 6 genes, 10 drugs (DrugBank) and 45 diseases shown 
 1件: IFNAR1   D04554   Interferon beta-1a   5件: 13, 14, 26, 96, 97 
 1件: JAK1   D10871   Filgotinib   6件: 46, 53, 96, 97, 222, 271 
 D10944   Itacitinib   4件: 46, 60, 97, 228 
 D10994   Upadacitinib   6件: 41, 46, 49, 96, 97, 271 
 4件: JAK1, JAK2, JAK3, TYK2   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 67  Hepatitis C 
 5 genes, 10 drugs (DrugBank) and 45 diseases shown 
 2件: IFNAR1, IFNAR2   D04554   Interferon beta-1a   5件: 13, 14, 26, 96, 97 
 1件: JAK1   D10871   Filgotinib   6件: 46, 53, 96, 97, 222, 271 
 D10944   Itacitinib   4件: 46, 60, 97, 228 
 D10994   Upadacitinib   6件: 41, 46, 49, 96, 97, 271 
 2件: JAK1, TYK2   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 68  Herpes simplex virus 1 infection 
 8 genes, 11 drugs (DrugBank) and 46 diseases shown 
 2件: IFNAR1, IFNAR2   D04554   Interferon beta-1a   5件: 13, 14, 26, 96, 97 
 2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: JAK1   D10871   Filgotinib   6件: 46, 53, 96, 97, 222, 271 
 D10944   Itacitinib   4件: 46, 60, 97, 228 
 D10994   Upadacitinib   6件: 41, 46, 49, 96, 97, 271 
 3件: JAK1, JAK2, TYK2   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 69  Hippo signaling pathway 
 1 gene, 1 drug (DrugBank) and 2 diseases shown 
 1件: SMAD7   D10956   Mongersen   2件: 96, 97 
 70  Human cytomegalovirus infection 
 7 genes, 11 drugs (DrugBank) and 69 diseases shown 
 1件: JAK1   D10871   Filgotinib   6件: 46, 53, 96, 97, 222, 271 
 D10944   Itacitinib   4件: 46, 60, 97, 228 
 D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 D10994   Upadacitinib   6件: 41, 46, 49, 96, 97, 271 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 71  Human immunodeficiency virus 1 infection 
 9 genes, 9 drugs (DrugBank) and 68 diseases shown 
 3件: CD3D, CD3E, CD3G   D05092   Muromonab   3件: 60, 96, 97 
 D06314   Visilizumab   2件: 96, 97 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 72  Human papillomavirus infection 
 7 genes, 12 drugs (DrugBank) and 45 diseases shown 
 2件: IFNAR1, IFNAR2   D04554   Interferon beta-1a   5件: 13, 14, 26, 96, 97 
 2件: ITGA4, ITGB7   D08083   Vedolizumab   2件: 96, 97 
 1件: ITGB7   D09901   Etrolizumab   2件: 96, 97 
 1件: JAK1   D10871   Filgotinib   6件: 46, 53, 96, 97, 222, 271 
 D10944   Itacitinib   4件: 46, 60, 97, 228 
 D10994   Upadacitinib   6件: 41, 46, 49, 96, 97, 271 
 2件: JAK1, TYK2   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 73  Human T-cell leukemia virus 1 infection 
 14 genes, 16 drugs (DrugBank) and 69 diseases shown 
 3件: CD3D, CD3E, CD3G   D05092   Muromonab   3件: 60, 96, 97 
 D06314   Visilizumab   2件: 96, 97 
 1件: IL2RA   D03058   Basiliximab   7件: 2, 50, 65, 66, 97, 222, 228 
 D03639   Daclizumab   7件: 13, 56, 60, 65, 97, 283, 284 
 3件: IL2RA, IL2RB, IL2RG   D00748   Aldesleukin   4件: 2, 49, 65, 97 
 1件: JAK1   D10871   Filgotinib   6件: 46, 53, 96, 97, 222, 271 
 D10944   Itacitinib   4件: 46, 60, 97, 228 
 D10994   Upadacitinib   6件: 41, 46, 49, 96, 97, 271 
 2件: JAK1, JAK3   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 74  Huntington disease 
 3 genes, 2 drugs (DrugBank) and 12 diseases shown 
 2件: GRIN1, GRIN2B   D00848   Dextromethorphan   9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 
 D03742 
 D03744 
 1件: PPARG   D00596   Rosiglitazone   5件: 46, 75, 97, 222, 265 
 D08491 
 75  Hypertrophic cardiomyopathy (HCM) 
 7 genes, 8 drugs (DrugBank) and 42 diseases shown 
 4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4   D00332   Gabapentin   7件: 6, 13, 19, 70, 97, 226, 298 
 2件: ITGA4, ITGB7   D08083   Vedolizumab   2件: 96, 97 
 1件: ITGB7   D09901   Etrolizumab   2件: 96, 97 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 76  IL-17 signaling pathway 
 4 genes, 8 drugs (DrugBank) and 39 diseases shown 
 1件: IL13   D08857   Anrukinzumab   1件: 97 
 D09979   Tralokinumab   2件: 85, 97 
 2件: IL17A, IL17F   D11550   Bimekizumab   3件: 46, 97, 271 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 77  Inflammatory bowel disease (IBD) 
 8 genes, 13 drugs (DrugBank) and 41 diseases shown 
 3件: IL12A, IL12B, IL23A   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL13   D08857   Anrukinzumab   1件: 97 
 D09979   Tralokinumab   2件: 85, 97 
 2件: IL17A, IL17F   D11550   Bimekizumab   3件: 46, 97, 271 
 1件: IL23A   D10438   Guselkumab   3件: 37, 96, 97 
 D11123   Mirikizumab   2件: 96, 97 
 D11052   Risankizumab   4件: 37, 96, 97, 271 
 1件: IL2RG   D00748   Aldesleukin   4件: 2, 49, 65, 97 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 78  Inflammatory mediator regulation of TRP channels 
 4 genes, 1 drug (DrugBank) and 1 disease shown 
 4件: PRKCD, PRKCE, PRKCH, PRKCQ   D09671   Sotrastaurin   1件: 97 
 79  Influenza A 
 8 genes, 11 drugs (DrugBank) and 46 diseases shown 
 2件: IFNAR1, IFNAR2   D04554   Interferon beta-1a   5件: 13, 14, 26, 96, 97 
 2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: JAK1   D10871   Filgotinib   6件: 46, 53, 96, 97, 222, 271 
 D10944   Itacitinib   4件: 46, 60, 97, 228 
 D10994   Upadacitinib   6件: 41, 46, 49, 96, 97, 271 
 3件: JAK1, JAK2, TYK2   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 80  Insulin resistance 
 4 genes, 6 drugs (DrugBank) and 39 diseases shown 
 3件: PRKCD, PRKCE, PRKCQ   D09671   Sotrastaurin   1件: 97 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 81  Insulin signaling pathway 
 1 gene, 1 drug (DrugBank) and 6 diseases shown 
 1件: PDE3B   D00528   Caffeine   6件: 2, 6, 46, 78, 96, 97 
 D01453 
 82  Intestinal immune network for IgA production 
 4 genes, 3 drugs (DrugBank) and 24 diseases shown 
 2件: CD80, CD86   D03203   Abatacept   24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 2件: ITGA4, ITGB7   D08083   Vedolizumab   2件: 96, 97 
 1件: ITGB7   D09901   Etrolizumab   2件: 96, 97 
 83  JAK-STAT signaling pathway 
 13 genes, 14 drugs (DrugBank) and 28 diseases shown 
 2件: IFNAR1, IFNAR2   D04554   Interferon beta-1a   5件: 13, 14, 26, 96, 97 
 3件: IL12A, IL12B, IL23A   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL13   D08857   Anrukinzumab   1件: 97 
 D09979   Tralokinumab   2件: 85, 97 
 1件: IL23A   D10438   Guselkumab   3件: 37, 96, 97 
 D11123   Mirikizumab   2件: 96, 97 
 D11052   Risankizumab   4件: 37, 96, 97, 271 
 1件: IL2RA   D03058   Basiliximab   7件: 2, 50, 65, 66, 97, 222, 228 
 D03639   Daclizumab   7件: 13, 56, 60, 65, 97, 283, 284 
 3件: IL2RA, IL2RB, IL2RG   D00748   Aldesleukin   4件: 2, 49, 65, 97 
 1件: JAK1   D10871   Filgotinib   6件: 46, 53, 96, 97, 222, 271 
 D10944   Itacitinib   4件: 46, 60, 97, 228 
 D10994   Upadacitinib   6件: 41, 46, 49, 96, 97, 271 
 4件: JAK1, JAK2, JAK3, TYK2   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 84  Kaposi sarcoma-associated herpesvirus infection 
 11 genes, 8 drugs (DrugBank) and 61 diseases shown 
 1件: CD86   D03203   Abatacept   24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 2件: IFNAR1, IFNAR2   D04554   Interferon beta-1a   5件: 13, 14, 26, 96, 97 
 1件: JAK1   D10871   Filgotinib   6件: 46, 53, 96, 97, 222, 271 
 D10944   Itacitinib   4件: 46, 60, 97, 228 
 D10994   Upadacitinib   6件: 41, 46, 49, 96, 97, 271 
 3件: JAK1, JAK2, TYK2   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 85  Legionellosis 
 3 genes, 6 drugs (DrugBank) and 41 diseases shown 
 2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 86  Leishmaniasis 
 6 genes, 11 drugs (DrugBank) and 44 diseases shown 
 2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: ITGA4   D08083   Vedolizumab   2件: 96, 97 
 1件: JAK1   D10871   Filgotinib   6件: 46, 53, 96, 97, 222, 271 
 D10944   Itacitinib   4件: 46, 60, 97, 228 
 D10994   Upadacitinib   6件: 41, 46, 49, 96, 97, 271 
 2件: JAK1, JAK2   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 87  Leukocyte transendothelial migration 
 1 gene, 1 drug (DrugBank) and 2 diseases shown 
 1件: ITGA4   D08083   Vedolizumab   2件: 96, 97 
 88  Long-term potentiation 
 10 genes, 3 drugs (DrugBank) and 59 diseases shown 
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   D00848   Dextromethorphan   9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 
 D03742 
 D03744 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 89  Longevity regulating pathway 
 1 gene, 1 drug (DrugBank) and 5 diseases shown 
 1件: PPARG   D00596   Rosiglitazone   5件: 46, 75, 97, 222, 265 
 D08491 
 90  Malaria 
 2 genes, 6 drugs (DrugBank) and 41 diseases shown 
 1件: IL12A   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 91  MAPK signaling pathway 
 10 genes, 8 drugs (DrugBank) and 70 diseases shown 
 4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4   D00332   Gabapentin   7件: 6, 13, 19, 70, 97, 226, 298 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 92  Measles 
 13 genes, 11 drugs (DrugBank) and 27 diseases shown 
 3件: CD3D, CD3E, CD3G   D05092   Muromonab   3件: 60, 96, 97 
 D06314   Visilizumab   2件: 96, 97 
 2件: IFNAR1, IFNAR2   D04554   Interferon beta-1a   5件: 13, 14, 26, 96, 97 
 2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL2RA   D03058   Basiliximab   7件: 2, 50, 65, 66, 97, 222, 228 
 D03639   Daclizumab   7件: 13, 56, 60, 65, 97, 283, 284 
 3件: IL2RA, IL2RB, IL2RG   D00748   Aldesleukin   4件: 2, 49, 65, 97 
 1件: JAK1   D10871   Filgotinib   6件: 46, 53, 96, 97, 222, 271 
 D10944   Itacitinib   4件: 46, 60, 97, 228 
 D10994   Upadacitinib   6件: 41, 46, 49, 96, 97, 271 
 3件: JAK1, JAK3, TYK2   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107,