Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Focal adhesion 💬
1件: BCL2 💬 D10679 💬 Venetoclax 1件: 28 💬
2 Focal adhesion 💬
1件: BRAF 💬 D10064 💬 Dabrafenib 1件: 34 💬
3 Focal adhesion 💬
5件: BRAF, FLT4, KDR, PDGFRB, RAF1 💬 D06272 💬 Sorafenib 2件: 34, 86 💬
4 Focal adhesion 💬
5件: BRAF, FLT4, KDR, PDGFRB, RAF1 💬 D08524 💬 Sorafenib 2件: 34, 86 💬
5 Focal adhesion 💬
1件: EGFR 💬 D03455 💬 Cetuximab 5件: 34, 51, 86, 89, 331 💬
6 Focal adhesion 💬
1件: EGFR 💬 D04023 💬 Erlotinib 1件: 94 💬
7 Focal adhesion 💬
1件: EGFR 💬 D07907 💬 Erlotinib 1件: 94 💬
8 Focal adhesion 💬
1件: EGFR 💬 D01977 💬 Gefitinib 1件: 75 💬
9 Focal adhesion 💬
1件: EGFR 💬 D11251 💬 Icotinib 1件: 34 💬
10 Focal adhesion 💬
2件: EGFR, ERBB2 💬 D04024 💬 Lapatinib 3件: 34, 74, 75 💬
11 Focal adhesion 💬
2件: EGFR, ERBB2 💬 D08108 💬 Lapatinib 3件: 34, 74, 75 💬
12 Focal adhesion 💬
4件: EGFR, ERBB2, FLT4, KDR 💬 D11772 💬 Tesevatinib 1件: 67 💬
13 Focal adhesion 💬
3件: FLT1, FLT4, KDR 💬 D03218 💬 Axitinib 1件: 34 💬
14 Focal adhesion 💬
3件: FLT1, FLT4, KDR 💬 D08881 💬 Cediranib 1件: 34 💬
15 Focal adhesion 💬
5件: FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 D10481 💬 Nintedanib 5件: 51, 85, 89, 227, 228 💬
16 Focal adhesion 💬
5件: FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 D06402 💬 Sunitinib 2件: 28, 34 💬
17 Focal adhesion 💬
5件: FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 D08552 💬 Sunitinib 2件: 28, 34 💬
18 Focal adhesion 💬
3件: FYN, PDGFRB, SRC 💬 D03658 💬 Dasatinib 2件: 51, 85 💬
19 Focal adhesion 💬
3件: FYN, PDGFRB, SRC 💬 D06414 💬 Dasatinib 2件: 51, 85 💬
20 Focal adhesion 💬
1件: IGF1R 💬 D09925 💬 Linsitinib 1件: 232 💬
21 Focal adhesion 💬
1件: IGF1R 💬 D03297 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
22 Focal adhesion 💬
1件: IGF1R 💬 D04870 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
23 Focal adhesion 💬
1件: IGF1R 💬 D09680 💬 Teprotumumab 1件: 51 💬
24 Focal adhesion 💬
1件: ITGA4 💬 D06590 💬 Firategrast 1件: 13 💬
25 Focal adhesion 💬
1件: ITGA4 💬 D06886 💬 Natalizumab 6件: 13, 15, 25, 46, 63, 96 💬
26 Focal adhesion 💬
2件: ITGA4, ITGB7 💬 D10540 💬 Abrilumab 2件: 96, 97 💬
27 Focal adhesion 💬
2件: ITGA4, ITGB7 💬 D08083 💬 Vedolizumab 3件: 94, 96, 97 💬
28 Focal adhesion 💬
1件: ITGB7 💬 D09901 💬 Etrolizumab 2件: 96, 97 💬
29 Focal adhesion 💬
2件: KDR, MET 💬 D10062 💬 Cabozantinib 1件: 34 💬
30 Focal adhesion 💬
1件: MAP2K1 💬 D10604 💬 Binimetinib 1件: 34 💬
31 Focal adhesion 💬
1件: MAP2K1 💬 D10405 💬 Cobimetinib 1件: 280 💬
32 Focal adhesion 💬
1件: MAP2K1 💬 D09666 💬 Selumetinib 1件: 34 💬
33 Focal adhesion 💬
1件: MAP2K1 💬 D10175 💬 Trametinib 4件:  2 , 34, 279, 280 💬
34 Focal adhesion 💬
1件: PDGFRA 💬 D01441 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
35 Focal adhesion 💬
1件: PDGFRA 💬 D08066 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
36 Focal adhesion 💬
2件: PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬
37 Focal adhesion 💬
3件: PGF, VEGFA, VEGFB 💬 D09574 💬 Aflibercept 2件: 90, 166 💬
38 Focal adhesion 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
39 Focal adhesion 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
40 Focal adhesion 💬
2件: ROCK1, ROCK2 💬 D07941 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
41 Focal adhesion 💬
1件: ROCK2 💬 D11815 💬 Belumosudil 1件: 51 💬
42 Focal adhesion 💬
1件: SRC 💬 D03252 💬 Bosutinib 2件:  2 , 67 💬
43 Focal adhesion 💬
1件: SRC 💬 D09664 💬 Saracatinib 3件:  6 , 89, 272 💬
44 Focal adhesion 💬
1件: VEGFA 💬 D06409 💬 Bevacizumab 9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
45 Focal adhesion 💬
1件: VEGFA 💬 D05697 💬 Ranibizumab 4件: 34, 166, 227, 301 💬
46 Focal adhesion 💬
1件: VWF 💬 D11160 💬 Caplacizumab 1件: 64 💬