Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Oxytocin signaling pathway 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00615 💬 Amlodipine 4件: 13, 51, 67, 298 💬
2 Oxytocin signaling pathway 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D02914 💬 Amlodipine 4件: 13, 51, 67, 298 💬
3 Oxytocin signaling pathway 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07450 💬 Amlodipine 4件: 13, 51, 67, 298 💬
4 Oxytocin signaling pathway 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D01173 💬 Cilnidipine 1件: 67 💬
5 Oxytocin signaling pathway 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00616 💬 Diltiazem 3件: 51, 58, 86 💬
6 Oxytocin signaling pathway 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D03830 💬 Diltiazem 3件: 51, 58, 86 💬
7 Oxytocin signaling pathway 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem 3件: 51, 58, 86 💬
8 Oxytocin signaling pathway 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00349 💬 Isradipine 1件:  6  💬
9 Oxytocin signaling pathway 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00617 💬 Nicardipine 2件: 70, 86 💬
10 Oxytocin signaling pathway 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine 2件: 70, 86 💬
11 Oxytocin signaling pathway 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00437 💬 Nifedipine 2件: 50, 81 💬
12 Oxytocin signaling pathway 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D01908 💬 Nilvadipine 1件: 90 💬
13 Oxytocin signaling pathway 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D05442 💬 Perhexiline 2件: 58, 272 💬
14 Oxytocin signaling pathway 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08340 💬 Perhexiline 2件: 58, 272 💬
15 Oxytocin signaling pathway 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine 1件: 226 💬
16 Oxytocin signaling pathway 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
17 Oxytocin signaling pathway 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00619 💬 Verapamil 3件: 96, 140, 167 💬
18 Oxytocin signaling pathway 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D02356 💬 Verapamil 3件: 96, 140, 167 💬
19 Oxytocin signaling pathway 💬
2件: CACNA2D1, CACNA2D2 💬 D11203 💬 Mirogabalin 1件: 70 💬
20 Oxytocin signaling pathway 💬
4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 D00332 💬 Gabapentin 5件:  6 , 13, 19, 70, 298 💬
21 Oxytocin signaling pathway 💬
4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 D02716 💬 Pregabalin 5件: 13, 36, 46, 70, 298 💬
22 Oxytocin signaling pathway 💬
1件: CD38 💬 D10777 💬 Daratumumab 5件: 16, 28, 49, 63, 222 💬
23 Oxytocin signaling pathway 💬
1件: CD38 💬 D11050 💬 Isatuximab 2件: 28, 61 💬
24 Oxytocin signaling pathway 💬
1件: CD38 💬 D11945 💬 Mezagitamab 1件: 66 💬
25 Oxytocin signaling pathway 💬
1件: EGFR 💬 D03455 💬 Cetuximab 5件: 34, 51, 86, 89, 331 💬
26 Oxytocin signaling pathway 💬
1件: EGFR 💬 D04023 💬 Erlotinib 1件: 94 💬
27 Oxytocin signaling pathway 💬
1件: EGFR 💬 D07907 💬 Erlotinib 1件: 94 💬
28 Oxytocin signaling pathway 💬
1件: EGFR 💬 D01977 💬 Gefitinib 1件: 75 💬
29 Oxytocin signaling pathway 💬
1件: EGFR 💬 D11251 💬 Icotinib 1件: 34 💬
30 Oxytocin signaling pathway 💬
1件: EGFR 💬 D04024 💬 Lapatinib 3件: 34, 74, 75 💬
31 Oxytocin signaling pathway 💬
1件: EGFR 💬 D08108 💬 Lapatinib 3件: 34, 74, 75 💬
32 Oxytocin signaling pathway 💬
1件: EGFR 💬 D11772 💬 Tesevatinib 1件: 67 💬
33 Oxytocin signaling pathway 💬
3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 D00517 💬 Amyl Nitrite 1件: 58 💬
34 Oxytocin signaling pathway 💬
3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat 6件: 51, 84, 86, 88, 225, 299 💬
35 Oxytocin signaling pathway 💬
3件: KCNJ12, KCNJ3, KCNJ5 💬 D00636 💬 Amiodarone 2件: 28, 127 💬
36 Oxytocin signaling pathway 💬
3件: KCNJ12, KCNJ3, KCNJ5 💬 D02910 💬 Amiodarone 2件: 28, 127 💬
37 Oxytocin signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib 1件: 34 💬
38 Oxytocin signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib 1件: 280 💬
39 Oxytocin signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib 1件: 34 💬
40 Oxytocin signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 D10175 💬 Trametinib 4件:  2 , 34, 279, 280 💬
41 Oxytocin signaling pathway 💬
1件: NPR1 💬 D05147 💬 Nesiritide 2件: 46, 58 💬
42 Oxytocin signaling pathway 💬
2件: NPR1, NPR2 💬 D04051 💬 Erythrityl tetranitrate 1件: 46 💬
43 Oxytocin signaling pathway 💬
1件: NPR2 💬 D11190 💬 Vosoritide 1件: 276 💬
44 Oxytocin signaling pathway 💬
1件: OXTR 💬 D03008 💬 Atosiban 1件: 118 💬
45 Oxytocin signaling pathway 💬
1件: OXTR 💬 D07229 💬 Carbetocin 1件: 193 💬
46 Oxytocin signaling pathway 💬
1件: OXTR 💬 D00089 💬 Oxytocin 6件:  6 , 72, 127, 193, 206, 226 💬
47 Oxytocin signaling pathway 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
48 Oxytocin signaling pathway 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D05480 💬 Pimecrolimus 1件: 160 💬
49 Oxytocin signaling pathway 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
50 Oxytocin signaling pathway 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
51 Oxytocin signaling pathway 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D09033 💬 Voclosporin 1件: 222 💬
52 Oxytocin signaling pathway 💬
2件: PRKAA1, PRKAA2 💬 D00944 💬 Metformin 24件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
53 Oxytocin signaling pathway 💬
2件: PRKAA1, PRKAA2 💬 D04966 💬 Metformin 24件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
54 Oxytocin signaling pathway 💬
1件: PTGS2 💬 D01545 💬 Aceclofenac 1件: 46 💬
55 Oxytocin signaling pathway 💬
1件: PTGS2 💬 D00217 💬 Acetaminophen 18件:  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬
56 Oxytocin signaling pathway 💬
1件: PTGS2 💬 D00109 💬 Acetylsalicylic acid 15件: 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬
57 Oxytocin signaling pathway 💬
1件: PTGS2 💬 D00567 💬 Celecoxib 10件:  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
58 Oxytocin signaling pathway 💬
1件: PTGS2 💬 D00903 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
59 Oxytocin signaling pathway 💬
1件: PTGS2 💬 D00904 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
60 Oxytocin signaling pathway 💬
1件: PTGS2 💬 D07816 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
61 Oxytocin signaling pathway 💬
1件: PTGS2 💬 D00130 💬 Diflunisal 1件: 28 💬
62 Oxytocin signaling pathway 💬
1件: PTGS2 💬 D00315 💬 Etodolac 1件: 46 💬
63 Oxytocin signaling pathway 💬
1件: PTGS2 💬 D03710 💬 Etoricoxib 2件: 46, 271 💬
64 Oxytocin signaling pathway 💬
1件: PTGS2 💬 D00330 💬 Flurbiprofen 3件: 13, 21, 46 💬
65 Oxytocin signaling pathway 💬
1件: PTGS2 💬 D01475 💬 Flurbiprofen 3件: 13, 21, 46 💬
66 Oxytocin signaling pathway 💬
1件: PTGS2 💬 D02290 💬 Flurbiprofen 3件: 13, 21, 46 💬
67 Oxytocin signaling pathway 💬
1件: PTGS2 💬 D00126 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬
68 Oxytocin signaling pathway 💬
1件: PTGS2 💬 D01122 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬
69 Oxytocin signaling pathway 💬
1件: PTGS2 💬 D04490 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬
70 Oxytocin signaling pathway 💬
1件: PTGS2 💬 D06606 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬
71 Oxytocin signaling pathway 💬
1件: PTGS2 💬 D00141 💬 Indomethacin 3件: 225, 271, 298 💬
72 Oxytocin signaling pathway 💬
1件: PTGS2 💬 D01565 💬 Indomethacin 3件: 225, 271, 298 💬
73 Oxytocin signaling pathway 💬
1件: PTGS2 💬 D02110 💬 Indomethacin 3件: 225, 271, 298 💬
74 Oxytocin signaling pathway 💬
1件: PTGS2 💬 D00132 💬 Ketoprofen 1件: 46 💬
75 Oxytocin signaling pathway 💬
1件: PTGS2 💬 D00813 💬 Ketorolac 2件: 70, 226 💬
76 Oxytocin signaling pathway 💬
1件: PTGS2 💬 D08104 💬 Ketorolac 2件: 70, 226 💬
77 Oxytocin signaling pathway 💬
1件: PTGS2 💬 D08149 💬 Loxoprofen 2件: 46, 271 💬
78 Oxytocin signaling pathway 💬
1件: PTGS2 💬 D03714 💬 Lumiracoxib 1件: 46 💬
79 Oxytocin signaling pathway 💬
1件: PTGS2 💬 D00969 💬 Meloxicam 4件: 46, 49, 271, 296 💬
80 Oxytocin signaling pathway 💬
1件: PTGS2 💬 D00118 💬 Naproxen 4件: 13, 46, 107, 271 💬
81 Oxytocin signaling pathway 💬
1件: PTGS2 💬 D01049 💬 Nimesulide 1件: 46 💬
82 Oxytocin signaling pathway 💬
1件: PTGS2 💬 D03716 💬 Parecoxib 2件: 46, 271 💬
83 Oxytocin signaling pathway 💬
1件: PTGS2 💬 D00568 💬 Rofecoxib 1件: 46 💬
84 Oxytocin signaling pathway 💬
1件: PTGS2 💬 D00428 💬 Salsalate 1件:  5  💬
85 Oxytocin signaling pathway 💬
1件: PTGS2 💬 D00120 💬 Sulindac 1件: 206 💬
86 Oxytocin signaling pathway 💬
1件: PTGS2 💬 D01183 💬 Tolfenamic acid 1件:  5  💬
87 Oxytocin signaling pathway 💬
1件: PTGS2 💬 D02709 💬 Valdecoxib 1件: 46 💬
88 Oxytocin signaling pathway 💬
1件: RAF1 💬 D06272 💬 Sorafenib 2件: 34, 86 💬
89 Oxytocin signaling pathway 💬
1件: RAF1 💬 D08524 💬 Sorafenib 2件: 34, 86 💬
90 Oxytocin signaling pathway 💬
2件: ROCK1, ROCK2 💬 D07941 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
91 Oxytocin signaling pathway 💬
1件: ROCK2 💬 D11815 💬 Belumosudil 1件: 51 💬
92 Oxytocin signaling pathway 💬
1件: SRC 💬 D03252 💬 Bosutinib 2件:  2 , 67 💬
93 Oxytocin signaling pathway 💬
1件: SRC 💬 D03658 💬 Dasatinib 2件: 51, 85 💬
94 Oxytocin signaling pathway 💬
1件: SRC 💬 D06414 💬 Dasatinib 2件: 51, 85 💬
95 Oxytocin signaling pathway 💬
1件: SRC 💬 D09664 💬 Saracatinib 3件:  6 , 89, 272 💬