Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Phospholipase D signaling pathway 💬
1件: AGTR1 💬 D00150 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬
2 Phospholipase D signaling pathway 💬
1件: AGTR1 💬 D02014 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬
3 Phospholipase D signaling pathway 💬
1件: AGTR1 💬 D00522 💬 Candesartan 2件: 58, 67 💬
4 Phospholipase D signaling pathway 💬
1件: AGTR1 💬 D00522 💬 Candesartan cilexetil 1件: 67 💬
5 Phospholipase D signaling pathway 💬
1件: AGTR1 💬 D00626 💬 Candesartan cilexetil 1件: 67 💬
6 Phospholipase D signaling pathway 💬
1件: AGTR1 💬 D00523 💬 Irbesartan 4件: 66, 167, 168, 222 💬
7 Phospholipase D signaling pathway 💬
1件: AGTR1 💬 D00357 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
8 Phospholipase D signaling pathway 💬
1件: AGTR1 💬 D08146 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
9 Phospholipase D signaling pathway 💬
1件: AGTR1 💬 D11776 💬 Sparsentan 3件: 66, 218, 222 💬
10 Phospholipase D signaling pathway 💬
1件: AGTR1 💬 D00627 💬 Telmisartan 2件: 66, 67 💬
11 Phospholipase D signaling pathway 💬
1件: AGTR1 💬 D00400 💬 Valsartan 7件: 57, 58, 66, 75, 218, 222, 224 💬
12 Phospholipase D signaling pathway 💬
3件: AVPR1A, AVPR1B, AVPR2 💬 D06672 💬 Terlipressin 1件: 299 💬
13 Phospholipase D signaling pathway 💬
3件: AVPR1A, AVPR1B, AVPR2 💬 D00101 💬 Vasopressin 1件: 210 💬
14 Phospholipase D signaling pathway 💬
2件: AVPR1A, AVPR2 💬 D01236 💬 Conivaptan 1件: 86 💬
15 Phospholipase D signaling pathway 💬
2件: AVPR1A, AVPR2 💬 D07748 💬 Conivaptan 1件: 86 💬
16 Phospholipase D signaling pathway 💬
1件: AVPR2 💬 D00291 💬 Desmopressin 6件:  6 , 64, 72, 75, 225, 288 💬
17 Phospholipase D signaling pathway 💬
1件: AVPR2 💬 D02235 💬 Desmopressin 6件:  6 , 64, 72, 75, 225, 288 💬
18 Phospholipase D signaling pathway 💬
1件: AVPR2 💬 D04752 💬 Lixivaptan 1件: 67 💬
19 Phospholipase D signaling pathway 💬
1件: AVPR2 💬 D01213 💬 Tolvaptan 3件: 67, 72, 225 💬
20 Phospholipase D signaling pathway 💬
2件: CXCR1, CXCR2 💬 D08984 💬 Reparixin 2件: 298, 299 💬
21 Phospholipase D signaling pathway 💬
1件: EGFR 💬 D03455 💬 Cetuximab 5件: 34, 51, 86, 89, 331 💬
22 Phospholipase D signaling pathway 💬
1件: EGFR 💬 D04023 💬 Erlotinib 1件: 94 💬
23 Phospholipase D signaling pathway 💬
1件: EGFR 💬 D07907 💬 Erlotinib 1件: 94 💬
24 Phospholipase D signaling pathway 💬
1件: EGFR 💬 D01977 💬 Gefitinib 1件: 75 💬
25 Phospholipase D signaling pathway 💬
1件: EGFR 💬 D11251 💬 Icotinib 1件: 34 💬
26 Phospholipase D signaling pathway 💬
1件: EGFR 💬 D04024 💬 Lapatinib 3件: 34, 74, 75 💬
27 Phospholipase D signaling pathway 💬
1件: EGFR 💬 D08108 💬 Lapatinib 3件: 34, 74, 75 💬
28 Phospholipase D signaling pathway 💬
1件: EGFR 💬 D11772 💬 Tesevatinib 1件: 67 💬
29 Phospholipase D signaling pathway 💬
1件: F2 💬 D09707 💬 Dabigatran 4件: 51, 85, 91, 124 💬
30 Phospholipase D signaling pathway 💬
1件: F2 💬 D07144 💬 Dabigatran etexilate 1件: 51 💬
31 Phospholipase D signaling pathway 💬
1件: F2 💬 D06410 💬 Thrombomodulin Alfa 1件: 85 💬
32 Phospholipase D signaling pathway 💬
1件: FCER1A 💬 D05251 💬 Omalizumab 7件: 46, 53, 65, 98, 162, 226, 299 💬
33 Phospholipase D signaling pathway 💬
3件: FYN, KIT, PDGFRB 💬 D03658 💬 Dasatinib 2件: 51, 85 💬
34 Phospholipase D signaling pathway 💬
3件: FYN, KIT, PDGFRB 💬 D06414 💬 Dasatinib 2件: 51, 85 💬
35 Phospholipase D signaling pathway 💬
1件: INSR 💬 D04539 💬 Insulin detemir 1件: 299 💬
36 Phospholipase D signaling pathway 💬
1件: INSR 💬 D03250 💬 Insulin glargine 1件: 299 💬
37 Phospholipase D signaling pathway 💬
1件: INSR 💬 D00085 💬 Insulin human 2件: 96, 156 💬
38 Phospholipase D signaling pathway 💬
1件: INSR 💬 D03230 💬 Insulin human 2件: 96, 156 💬
39 Phospholipase D signaling pathway 💬
1件: KIT 💬 D10229 💬 Masitinib 6件:  2 ,  5 ,  6 , 13, 46, 96 💬
40 Phospholipase D signaling pathway 💬
1件: KIT 💬 D11270 💬 Pexidartinib 1件: 34 💬
41 Phospholipase D signaling pathway 💬
2件: KIT, PDGFRA 💬 D01441 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
42 Phospholipase D signaling pathway 💬
2件: KIT, PDGFRA 💬 D08066 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
43 Phospholipase D signaling pathway 💬
3件: KIT, PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬
44 Phospholipase D signaling pathway 💬
3件: KIT, PDGFRA, PDGFRB 💬 D06402 💬 Sunitinib 2件: 28, 34 💬
45 Phospholipase D signaling pathway 💬
3件: KIT, PDGFRA, PDGFRB 💬 D08552 💬 Sunitinib 2件: 28, 34 💬
46 Phospholipase D signaling pathway 💬
3件: KIT, PDGFRB, RAF1 💬 D06272 💬 Sorafenib 2件: 34, 86 💬
47 Phospholipase D signaling pathway 💬
3件: KIT, PDGFRB, RAF1 💬 D08524 💬 Sorafenib 2件: 34, 86 💬
48 Phospholipase D signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib 1件: 34 💬
49 Phospholipase D signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib 1件: 280 💬
50 Phospholipase D signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib 1件: 34 💬
51 Phospholipase D signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 D10175 💬 Trametinib 4件:  2 , 34, 279, 280 💬
52 Phospholipase D signaling pathway 💬
1件: MTOR 💬 D02714 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
53 Phospholipase D signaling pathway 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
54 Phospholipase D signaling pathway 💬
1件: MTOR 💬 D06068 💬 Temsirolimus 4件: 13, 34, 89, 331 💬
55 Phospholipase D signaling pathway 💬
2件: PDGFRA, PDGFRB 💬 D10481 💬 Nintedanib 5件: 51, 85, 89, 227, 228 💬
56 Phospholipase D signaling pathway 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
57 Phospholipase D signaling pathway 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
58 Phospholipase D signaling pathway 💬
1件: PTGFR 💬 D06274 💬 Tafluprost 1件: 299 💬
59 Phospholipase D signaling pathway 💬
1件: PTGFR 💬 D08661 💬 Unoprostone 1件: 90 💬
60 Phospholipase D signaling pathway 💬
1件: SYK 💬 D09347 💬 Fostamatinib 4件: 46, 49, 61, 66 💬