Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 VEGF signaling pathway 💬
1件: CASP9 💬 D11195 💬 Rimiducid 6件: 19, 60, 65, 284, 285, 326 💬
2 VEGF signaling pathway 💬
1件: KDR 💬 D03218 💬 Axitinib 1件: 34 💬
3 VEGF signaling pathway 💬
1件: KDR 💬 D10062 💬 Cabozantinib 1件: 34 💬
4 VEGF signaling pathway 💬
1件: KDR 💬 D08881 💬 Cediranib 1件: 34 💬
5 VEGF signaling pathway 💬
1件: KDR 💬 D10481 💬 Nintedanib 5件: 51, 85, 89, 227, 228 💬
6 VEGF signaling pathway 💬
1件: KDR 💬 D06402 💬 Sunitinib 2件: 28, 34 💬
7 VEGF signaling pathway 💬
1件: KDR 💬 D08552 💬 Sunitinib 2件: 28, 34 💬
8 VEGF signaling pathway 💬
1件: KDR 💬 D11772 💬 Tesevatinib 1件: 67 💬
9 VEGF signaling pathway 💬
2件: KDR, RAF1 💬 D06272 💬 Sorafenib 2件: 34, 86 💬
10 VEGF signaling pathway 💬
2件: KDR, RAF1 💬 D08524 💬 Sorafenib 2件: 34, 86 💬
11 VEGF signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib 1件: 34 💬
12 VEGF signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib 1件: 280 💬
13 VEGF signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib 1件: 34 💬
14 VEGF signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 D10175 💬 Trametinib 4件:  2 , 34, 279, 280 💬
15 VEGF signaling pathway 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod 2件: 113, 222 💬
16 VEGF signaling pathway 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod 1件:  8  💬
17 VEGF signaling pathway 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
18 VEGF signaling pathway 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
19 VEGF signaling pathway 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
20 VEGF signaling pathway 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D05480 💬 Pimecrolimus 1件: 160 💬
21 VEGF signaling pathway 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
22 VEGF signaling pathway 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
23 VEGF signaling pathway 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D09033 💬 Voclosporin 1件: 222 💬
24 VEGF signaling pathway 💬
1件: PTGS2 💬 D01545 💬 Aceclofenac 1件: 46 💬
25 VEGF signaling pathway 💬
1件: PTGS2 💬 D00217 💬 Acetaminophen 18件:  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬
26 VEGF signaling pathway 💬
1件: PTGS2 💬 D00109 💬 Acetylsalicylic acid 15件: 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬
27 VEGF signaling pathway 💬
1件: PTGS2 💬 D00567 💬 Celecoxib 10件:  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
28 VEGF signaling pathway 💬
1件: PTGS2 💬 D00903 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
29 VEGF signaling pathway 💬
1件: PTGS2 💬 D00904 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
30 VEGF signaling pathway 💬
1件: PTGS2 💬 D07816 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
31 VEGF signaling pathway 💬
1件: PTGS2 💬 D00130 💬 Diflunisal 1件: 28 💬
32 VEGF signaling pathway 💬
1件: PTGS2 💬 D00315 💬 Etodolac 1件: 46 💬
33 VEGF signaling pathway 💬
1件: PTGS2 💬 D03710 💬 Etoricoxib 2件: 46, 271 💬
34 VEGF signaling pathway 💬
1件: PTGS2 💬 D00330 💬 Flurbiprofen 3件: 13, 21, 46 💬
35 VEGF signaling pathway 💬
1件: PTGS2 💬 D01475 💬 Flurbiprofen 3件: 13, 21, 46 💬
36 VEGF signaling pathway 💬
1件: PTGS2 💬 D02290 💬 Flurbiprofen 3件: 13, 21, 46 💬
37 VEGF signaling pathway 💬
1件: PTGS2 💬 D00126 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬
38 VEGF signaling pathway 💬
1件: PTGS2 💬 D01122 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬
39 VEGF signaling pathway 💬
1件: PTGS2 💬 D04490 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬
40 VEGF signaling pathway 💬
1件: PTGS2 💬 D06606 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬
41 VEGF signaling pathway 💬
1件: PTGS2 💬 D00141 💬 Indomethacin 3件: 225, 271, 298 💬
42 VEGF signaling pathway 💬
1件: PTGS2 💬 D01565 💬 Indomethacin 3件: 225, 271, 298 💬
43 VEGF signaling pathway 💬
1件: PTGS2 💬 D02110 💬 Indomethacin 3件: 225, 271, 298 💬
44 VEGF signaling pathway 💬
1件: PTGS2 💬 D00132 💬 Ketoprofen 1件: 46 💬
45 VEGF signaling pathway 💬
1件: PTGS2 💬 D00813 💬 Ketorolac 2件: 70, 226 💬
46 VEGF signaling pathway 💬
1件: PTGS2 💬 D08104 💬 Ketorolac 2件: 70, 226 💬
47 VEGF signaling pathway 💬
1件: PTGS2 💬 D08149 💬 Loxoprofen 2件: 46, 271 💬
48 VEGF signaling pathway 💬
1件: PTGS2 💬 D03714 💬 Lumiracoxib 1件: 46 💬
49 VEGF signaling pathway 💬
1件: PTGS2 💬 D00969 💬 Meloxicam 4件: 46, 49, 271, 296 💬
50 VEGF signaling pathway 💬
1件: PTGS2 💬 D00118 💬 Naproxen 4件: 13, 46, 107, 271 💬
51 VEGF signaling pathway 💬
1件: PTGS2 💬 D01049 💬 Nimesulide 1件: 46 💬
52 VEGF signaling pathway 💬
1件: PTGS2 💬 D03716 💬 Parecoxib 2件: 46, 271 💬
53 VEGF signaling pathway 💬
1件: PTGS2 💬 D00568 💬 Rofecoxib 1件: 46 💬
54 VEGF signaling pathway 💬
1件: PTGS2 💬 D00428 💬 Salsalate 1件:  5  💬
55 VEGF signaling pathway 💬
1件: PTGS2 💬 D00120 💬 Sulindac 1件: 206 💬
56 VEGF signaling pathway 💬
1件: PTGS2 💬 D01183 💬 Tolfenamic acid 1件:  5  💬
57 VEGF signaling pathway 💬
1件: PTGS2 💬 D02709 💬 Valdecoxib 1件: 46 💬
58 VEGF signaling pathway 💬
1件: SRC 💬 D03252 💬 Bosutinib 2件:  2 , 67 💬
59 VEGF signaling pathway 💬
1件: SRC 💬 D03658 💬 Dasatinib 2件: 51, 85 💬
60 VEGF signaling pathway 💬
1件: SRC 💬 D06414 💬 Dasatinib 2件: 51, 85 💬
61 VEGF signaling pathway 💬
1件: SRC 💬 D09664 💬 Saracatinib 3件:  6 , 89, 272 💬
62 VEGF signaling pathway 💬
1件: VEGFA 💬 D09574 💬 Aflibercept 2件: 90, 166 💬
63 VEGF signaling pathway 💬
1件: VEGFA 💬 D06409 💬 Bevacizumab 9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
64 VEGF signaling pathway 💬
1件: VEGFA 💬 D05697 💬 Ranibizumab 4件: 34, 166, 227, 301 💬