Drug Description in Trials / DrugBank / KEGG DRUG


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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Water 💬 [1] Water[8] AVONEX; ENBREL; Hiberix; Indocyanine green; OMNITROPE; Sterile Water for Injection; Water; WATER FOR INJECTION; --[21] 2, 5, 6, 13, 17, 22, 35, 46, 53, 57, 63, 65, 67, 78, 84, 96, 97, 206, 226, 278, 299 💬
2 Carbon dioxide 💬 [1] Carbon dioxide[1] Carbon dioxide; --[2] 97, 158 💬
3 Acetic acid, glacial 💬 [1] Acetic acid[2] Acetic acid; Ethanoate; --[2] 97, 251 💬
4 Glutamine 💬 [1] L-Glutamine[2] Glutamine; L-Glutamine; --[8] 87, 89, 96, 97, 113, 222, 245, 299 💬
5 Ascorbic acid 💬 [1] Ascorbic acid[4] Acidum ascorbicum; Ascorbic acid; Iron; Vitamin C; --[8] 10, 97, 192, 206, 210, 211, 212, 298 💬
6 Sucrose 💬 [1] Sucrose[1] Sucrose; --[3] 62, 96, 97 💬
7 Proline 💬 [1] Proline[1] Proline; --[2] 94, 97 💬
8 Niacinamide 💬 [1] Nicotinamide[3] Multivitamin; Niacinamide; NICOTINAMIDE; --[10] 2, 5, 6, 18, 49, 67, 97, 107, 162, 191 💬
9 Threonine 💬 [1] Threonine[1] Threonine; --[2] 86, 97 💬
10 Maltose 💬 [1] Maltose[1] Maltose; --[2] 96, 97 💬
11 Anhydrous lactose 💬 [1] Lactose[1] Lactose; --[6] 2, 6, 13, 97, 228, 310 💬
12 Riboflavin 💬 [1] Riboflavin[2] Riboflavin; Vitamin B2; --[7] 38, 46, 96, 97, 162, 168, 265 💬
13 Dextran 1 💬 [1] Dextran[1] Dextran; --[4] 2, 62, 96, 97 💬
14 Nitric oxide 💬 [1] Nitric Oxide[3] INOmax; NITRIC OXIDE; Nitrosyl; --[7] 85, 86, 88, 210, 251, 294, 299 💬
15 Hydrocortisone 💬 [1] Hydrocortisone[6] Cortef; Cortisol; Cortisone; HYDROCORTISONE; Hydrocortisone cream; Hydrocortisonum; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[10] 6, 41, 46, 53, 75, 78, 81, 83, 97, 299 💬
16 Salicylic acid 💬 [1] Salicylic acid[2] 2-Hydroxybenzoic acid; Salicylic acid; --[1] 97 💬
17 Tacrolimus 💬 [1] Tacrolimus[2] Prograf; TACROLIMUS; [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬
[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
18 Aspirin 💬 [1] Acetylsalicylic acid[2] ACETYLSALICYLIC ACID; Aspirin; [2] PTGS1,
PTGS2 💬
[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[12] 13, 22, 46, 49, 51, 58, 64, 86, 113, 158, 210, 231 💬
19 Gelatin 💬 [1] Gelatin[3] Gelatin; Gelatine; Sulfur Colloid; --[7] 19, 28, 62, 78, 97, 269, 299 💬
20 Albendazole 💬 [1] Albendazole[2] Albendazole; Eskazole; --[1] 96 💬
21 Methotrexate 💬 [1] Methotrexate[6] Methotrexat; METHOTREXATE; METHOTREXATE SODIUM; Metoject; METOTREXATO; Méthotrexate; [2] DHFR,
DHFR2 💬
[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
22 Mercaptopurine 💬 [1] Mercaptopurine[4] 6-Mercaptopurine; 6-MP; MERCAPTOPURINE; PURINETHOL; [1] HPRT1 💬[4] Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬[4] 65, 96, 97, 164 💬
23 Aminosalicylic acid 💬 [1] Aminosalicylic acid[2] 4-Aminosalicylic acid; Aminosalicylic acid; --[2] 96, 97 💬
24 Hydrocortisone acetate 💬 [1] Hydrocortisone acetate[2] Hydrocortisone; HYDROCORTISONE ACETATE; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 97 💬
25 Cyclosporine 💬 [1] Cyclosporine[10] CICLOSPORIN; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A; Ikervis; Neoral; RESTASIS; [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬
[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
26 Ciprofloxacin 💬 [1] Ciprofloxacin[2] Ciprofloxacin; CIPROFLOXACIN HYDROCHLORIDE; --[5] 2, 60, 96, 97, 299 💬
27 Ergocalciferol 💬 [1] Ergocalciferol[3] Ergocalciferol; Vitamin D; Vitamin D2; [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[6] 46, 49, 84, 96, 97, 299 💬
28 Cholecalciferol 💬 [1] Cholecalciferol[5] Cholecalciferol; COLECALCIFEROL; Multivitamin; Vitamin D; Vitamin D3; [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[16] 6, 13, 19, 20, 34, 46, 49, 51, 53, 60, 65, 96, 97, 228, 298, 299 💬
29 Tetracycline 💬 [1] Tetracycline[2] Tetracyclin; Tetracycline; --[5] 13, 36, 46, 53, 97 💬
30 Vancomycin 💬 [1] Vancomycin[1] Vancomycin; --[8] 13, 46, 70, 94, 96, 97, 296, 299 💬
31 Allopurinol 💬 [1] Allopurinol[2] ALLOPURINOL; ALLOPURINOL SODIUM; [1] XDH 💬[6] Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Peroxisome, Purine metabolism 💬[7] 6, 46, 57, 60, 66, 96, 97 💬
32 Amoxicillin 💬 [1] Amoxicillin[4] Amoxicilina; Amoxicillin; Amoxycillin; Augmentin; --[7] 6, 46, 63, 96, 97, 222, 299 💬
33 Azathioprine 💬 [1] Azathioprine[3] AZATHIOPRINE; Azatioprina; Imuran; --[21] 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162 💬
34 Budesonide 💬 [1] Budesonide[4] BUDESONIDE; Entocort; Jorveza; Symbicort; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[9] 66, 93, 94, 95, 96, 97, 98, 228, 299 💬
35 Captopril 💬 [1] Captopril[1] Captopril; [1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[2] 17, 86 💬
36 Cefuroxime 💬 [1] Cefuroxime[2] Cefuroxim; CEFUROXIME; --[2] 97, 299 💬
37 Clarithromycin 💬 [1] Clarithromycin[1] Clarithromycin; --[8] 6, 63, 84, 96, 97, 222, 228, 299 💬
38 Clotrimazole 💬 [1] Clotrimazole[1] Clotrimazole; --[1] 97 💬
39 Dexamethasone 💬 [1] Dexamethasone[5] Decadron; Dexametasona; Dexamethasone; Dexamethasone sodium phosphate; Maxidex; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[22] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 81, 84, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
40 Doxycycline 💬 [1] Doxycycline[4] Doxycyclin; Doxycycline; DOXYCYCLINE HYCLATE; Doxycycline Tablets; --[17] 13, 23, 28, 34, 46, 84, 85, 89, 96, 97, 158, 161, 162, 167, 227, 280, 299 💬
41 Ganciclovir 💬 [1] Ganciclovir[1] Ganciclovir; --[1] 97 💬
42 Mesalamine 💬 [1] Mesalazine[10] 5-Aminosalicylic acid; 5-ASA; ASACOL; Mesalamine; MESALAZINA; Mesalazine; Mesalazinum; MEZAVANT; Pentasa; Salofalk; --[5] 46, 96, 97, 98, 164 💬
43 Tromethamine 💬 [1] Tromethamine[4] Tham; Tris; Trometamol; Tromethamine; --[5] 51, 96, 97, 226, 299 💬
44 Methylprednisolone 💬 [1] Methylprednisolone[4] Medrol; Methylprednisolon; METHYLPREDNISOLONE; METHYLPREDNISOLONE ACETATE; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[46] 2, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
45 Metronidazole 💬 [1] Metronidazole[3] Flagyl; Metronidazol; METRONIDAZOLE; --[7] 46, 51, 63, 94, 96, 97, 291 💬
46 Niclosamide 💬 [1] Niclosamide[1] Niclosamide; --[2] 46, 97 💬
47 Omeprazole 💬 [1] Omeprazole[4] Losec; Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM; [2] ATP4A,
ATP4B 💬
[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[14] 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
48 Ondansetron 💬 [1] Ondansetron[1] Ondansetron; [5] HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬
[2] Serotonergic synapse, Taste transduction 💬[3] 6, 97, 107 💬
49 Prednisolone 💬 [1] Prednisolone[3] Prednisolona; PREDNISOLONE; Prednisolonum; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[42] 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
50 Prednisone 💬 [1] Prednisone[3] Prednisona; PREDNISONE; RAYOS; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[45] 2, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬
51 Pyrimethamine 💬 [1] Pyrimethamine[2] Daraprim; PYRIMETHAMINE; --[4] 2, 4, 19, 65 💬
52 Pentoxifylline 💬 [1] Pentoxifylline[1] Pentoxifylline; --[12] 26, 56, 84, 86, 93, 96, 97, 113, 220, 222, 296, 298 💬
53 Caffeine 💬 [1] Caffeine[1] Caffeine; [11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬
[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 21, 46, 78, 96, 97, 265 💬
54 Topiramate 💬 [1] Topiramate[2] TOPAMAX; Topiramate; [36] CA2,
CA4,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ,
GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬
[53] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 6, 97, 140, 144, 156, 193 💬
55 Midazolam 💬 [1] Midazolam[2] Midazolam; Midazolam injection; [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬
[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
56 Fenofibrate 💬 [1] Fenofibrate[1] Fenofibrate; [1] PPARA 💬[10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[6] 8, 79, 93, 94, 97, 265 💬
57 Beclomethasone dipropionate 💬 [1] Beclomethasone dipropionate[2] Beclometasone dipropionate; Beclomethasone dipropionate; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[3] 85, 97, 98 💬
58 Ursodiol 💬 [1] Ursodeoxycholic acid[4] UDCA; Ursodeoxycholic acid; Ursodiol; Ursofalk; [1] NR1H4 💬[1] Bile secretion 💬[14] 6, 8, 20, 46, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬
59 Aldesleukin 💬 [1] Aldesleukin[4] ALDESLEUKIN; ILT-101; Proleukin; Recombinant human interleukin-2; [3] IL2RA,
IL2RB,
IL2RG 💬
[14] Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Inflammatory bowel disease, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Primary immunodeficiency, Th1 and Th2 cell differentiation, Th17 cell differentiation, Transcriptional misregulation in cancer, Viral protein interaction with cytokine and cytokine receptor 💬[6] 2, 35, 49, 65, 96, 97 💬
60 Thalidomide 💬 [1] Thalidomide[1] Thalidomide; [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[20] 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
61 Hydroxocobalamin 💬 [1] Hydroxocobalamin[1] Hydroxocobalamin; --[1] 97 💬
62 Flupentixol 💬 [1] Flupentixol[1] Flupentixol; [2] DRD1,
DRD2 💬
[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 97 💬
63 Rebamipide 💬 [1] Rebamipide[1] Rebamipide; --[4] 46, 53, 97, 271 💬
64 Fluorescein 💬 [1] Fluorescein[1] Fluorescein; --[2] 22, 97 💬
65 Caffeine hydrate 💬 [1] Caffeine[1] Caffeine; [11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬
[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 21, 46, 78, 96, 97, 265 💬
66 Polaprezinc 💬 [1] Polaprezinc[1] Polaprezinc; --[2] 96, 97 💬
67 Iron dextran 💬 [1] Iron Dextran[1] Iron Dextran; --[1] 62 💬
68 Levocarnitine 💬 [1] Levocarnitine[4] Carnitine; L-Carnitine; Levocarnitine; Xyzal; --[11] 3, 5, 13, 53, 58, 86, 96, 97, 265, 298, 316 💬
69 Lysine 💬 [1] Lysine[1] Lysine; --[4] 13, 97, 228, 299 💬
70 Methylene blue 💬 [1] Methylene blue[2] METHYLENE BLUE; Methylthioninium chloride; --[2] 97, 127 💬
71 Alginic acid 💬 [1] Alginic acid[3] Algin; Alginate; Alginic acid; --[4] 51, 53, 97, 299 💬
72 Maltodextrin 💬 [1] Maltodextrin[1] Maltodextrin; --[4] 6, 13, 96, 97 💬
73 Vitamin E 💬 [1] Vitamin E[2] Alpha-tocopherol; Vitamin E; --[12] 2, 6, 13, 20, 46, 49, 90, 96, 97, 206, 299, 317 💬
74 Terbinafine 💬 [1] Terbinafine[1] Terbinafine; --[3] 96, 97, 271 💬
75 Nitazoxanide 💬 [1] Nitazoxanide[1] Nitazoxanide; --[3] 46, 96, 97 💬
76 Valganciclovir 💬 [1] Valganciclovir[1] Valganciclovir; --[4] 85, 97, 299, 331 💬
77 Rifaximin 💬 [1] Rifaximin[3] Rifaximin; RIFAXIMINA; Xifaxan; --[9] 6, 65, 93, 94, 96, 97, 99, 296, 299 💬
78 Adalimumab 💬 [1] Adalimumab[7] Adalimumab; Amgevita; Cyltezo; Hulio; HUMIRA; Hyrimoz; Imraldi; [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
79 Infliximab 💬 [1] Infliximab[6] Flixabi; Inflectra; Infliximab; Remicade; REMSIMA; Zessly; [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
80 Anakinra 💬 [1] Anakinra[2] Anakinra; Kineret; [2] IL1R1,
IL1R2 💬
[15] Amoebiasis, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Pathogenic Escherichia coli infection, Prostate cancer, Shigellosis, Th17 cell differentiation, Transcriptional misregulation in cancer 💬[18] 2, 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
81 Arginine 💬 [2] Arginine,
L-arginine
[6] Arginina; Arginine; L-Arg; L-Arginin; L-arginine; R-Gene; --[12] 46, 58, 65, 67, 78, 96, 97, 98, 113, 210, 251, 299 💬
82 Rituximab 💬 [1] Rituximab[6] MabThera; Rituxan; RITUXIMAB; Rixathon; Ruxience; TRUXIMA; [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[48] 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
83 Basiliximab 💬 [1] Basiliximab[2] Basiliximab; Simulect; [1] IL2RA 💬[11] Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[6] 2, 50, 66, 97, 222, 228 💬
84 Abatacept 💬 [1] Abatacept[2] Abatacept; ORENCIA; [2] CD80,
CD86 💬
[13] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬[26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
85 Lactose 💬 [1] Lactose[1] Lactose; --[6] 2, 6, 13, 97, 228, 310 💬
86 Magnesium citrate 💬 [1] Magnesium citrate[1] Magnesium citrate; --[1] 97 💬
87 Hetastarch 💬 [1] Hydroxyethyl Starch[1] Hextend; --[2] 96, 97 💬
88 Polyethylene glycol 3350 💬 [1] Polyethylene glycol[4] Macrogol; Macrogol 4000; Polyethylene glycol; Polyethylene Glycol 3350; --[7] 6, 78, 96, 97, 235, 276, 299 💬
89 Certolizumab pegol 💬 [1] Certolizumab pegol[2] CERTOLIZUMAB PEGOL; CIMZIA; [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[8] 37, 46, 49, 96, 97, 107, 226, 271 💬
90 Daclizumab 💬 [1] Daclizumab[3] Daclizumab; Zenapax; Zinbryta; [1] IL2RA 💬[11] Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[8] 13, 56, 60, 65, 97, 107, 283, 284 💬
91 Dextromethorphan 💬 [1] Dextromethorphan[4] Dextromethorphan; DEXTROMETHORPHAN HYDROBROMIDE; Dextrometorfano; Nuedexta; [6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬
[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156 💬
92 Entecavir 💬 [1] Entecavir[1] Entecavir; --[6] 46, 56, 96, 97, 107, 271 💬
93 Fosfomycin 💬 [1] Fosfomycin[1] Fosfomycin; --[2] 96, 97 💬
94 Lactomin 💬 [1] Lactobacillus acidophilus[4] Acidophilus; Lacteol; Lactobacillus; Lactobacillus acidophilus; --[3] 6, 49, 97 💬
95 Lactobacillus casei 💬 [1] Lactobacillus casei[2] Fusion; Lactobacillus casei; --[10] 6, 11, 13, 46, 49, 69, 70, 97, 271, 296 💬
96 Golimumab 💬 [1] Golimumab[2] GOLIMUMAB; SIMPONI; [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[8] 46, 56, 84, 96, 97, 107, 270, 271 💬
97 Interferon beta-1a 💬 [1] Interferon beta-1a[6] AVONEX; Interferon Beta 1-A; Interferon Beta 1a; Interferon beta-1a; Interferon-beta-1a; REBIF; [2] IFNAR1,
IFNAR2 💬
[18] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬[4] 13, 26, 96, 97 💬
98 Iron sucrose 💬 [1] Iron sucrose[1] Iron Sucrose; --[3] 62, 96, 97 💬
99 Lecithin 💬 [1] Lecithin[1] Phosphatidylcholine; --[1] 97 💬
100 Mercaptopurine 💬 [1] Mercaptopurine[4] 6-Mercaptopurine; 6-MP; MERCAPTOPURINE; PURINETHOL; [1] HPRT1 💬[4] Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬[4] 65, 96, 97, 164 💬
101 Metformin 💬 [1] Metformin[5] Metformin; Metformin HCl; Metformin hydrochloride; Metformina; Metformine; [2] PRKAA1,
PRKAA2 💬
[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[25] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
102 Methylprednisolone hemisuccinate 💬 [1] Methylprednisolone hemisuccinate[4] Methylprednisolone hemisuccinate; Methylprednisolone sodium succinate; Methylprednisolone succinate; Solu-Medrol; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[7] 13, 49, 50, 51, 53, 97, 211 💬
103 Molgramostim 💬 [1] Molgramostim[1] Molgramostim; [1] CSF2RA 💬[4] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬[3] 97, 229, 299 💬
104 Naltrexone 💬 [1] Naltrexone[2] Naltrexone; Naltrexone Hydrochloride; [3] OPRD1,
OPRK1,
OPRM1 💬
[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[12] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
105 Penicillin V 💬 [1] Phenoxymethylpenicillin[0] ---
106 Phentermine 💬 [1] Phentermine[1] Phentermine; [5] MAOA,
MAOB,
SLC6A2,
SLC6A3,
SLC6A4 💬
[16] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Phenylalanine metabolism, Serotonergic synapse, Synaptic vesicle cycle, Tryptophan metabolism, Tyrosine metabolism 💬[1] 97 💬
107 Plantago seed 💬 [1] Plantago seed[2] Psyllium; Psyllium husk; --[3] 6, 28, 97 💬
108 Roflumilast 💬 [1] Roflumilast[1] Roflumilast; [4] PDE4A,
PDE4B,
PDE4C,
PDE4D 💬
[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[4] 84, 97, 206, 299 💬
109 Visilizumab 💬 [1] Visilizumab[1] Visilizumab; [3] CD3D,
CD3E,
CD3G 💬
[11] Chagas disease, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬[2] 96, 97 💬
110 Ethanol 💬 [1] Ethanol[3] Alcohol; Ethanol; PREDNISONE; --[5] 58, 97, 279, 280, 298 💬
111 Donkey glue 💬 [1] Gelatin[3] Gelatin; Gelatine; Sulfur Colloid; --[7] 19, 28, 62, 78, 97, 269, 299 💬
112 Amitriptyline 💬 [1] Amitriptyline[3] Amitriptylin; Amitriptyline; Amitriptyline hydrochloride; [2] SLC6A2,
SLC6A4 💬
[2] Serotonergic synapse, Synaptic vesicle cycle 💬[4] 78, 97, 226, 299 💬
113 Amoxicillin 💬 [1] Amoxicillin[4] Amoxicilina; Amoxicillin; Amoxycillin; Augmentin; --[7] 6, 46, 63, 96, 97, 222, 299 💬
114 Atorvastatin 💬 [1] Atorvastatin[3] Atorvastatin; Atorvastatin Calcium; Lipitor; [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[19] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
115 Balsalazide 💬 [1] Balsalazide[3] 2-Hydroxybenzoic acid; Balsalazide; Balsalazide Disodium; --[1] 97 💬
116 Adomiparin 💬 [1] Parnaparin[2] Parnaparin; PARNAPARIN SODIUM; [1] SERPINC1 💬[1] Complement and coagulation cascades 💬[1] 97 💬
117 Aminolevulinic acid 💬 [1] Aminolevulinic acid[4] 5-ALA; 5-aminolevulinic acid; Aminolevulinic acid; Gliolan; --[5] 34, 96, 97, 180, 286 💬
118 Ceftriaxone 💬 [1] Ceftriaxone[1] CEFTRIAXONE; --[4] 2, 6, 46, 97 💬
119 Delorazepam 💬 [1] Delorazepam[0] [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬
[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬-
120 Diosmin 💬 [1] Diosmin[1] Diosmin; --[3] 46, 97, 265 💬
121 Doxycycline 💬 [1] Doxycycline[4] Doxycyclin; Doxycycline; Doxycycline Hyclate; Doxycycline Tablets; --[17] 13, 23, 28, 34, 46, 84, 85, 89, 96, 97, 158, 161, 162, 167, 227, 280, 299 💬
122 Entecavir 💬 [1] Entecavir[1] Entecavir; --[6] 46, 56, 96, 97, 107, 271 💬
123 Hyaluronic acid 💬 [1] Hyaluronic acid[2] Hyaluronate; Hyaluronic acid; --[6] 46, 53, 70, 97, 226, 231 💬
124 Hydroxychloroquine 💬 [1] Hydroxychloroquine[3] Hydroxychloroquine; Hydroxychloroquine Sulfate; Plaquenil; --[27] 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299 💬
125 Icosapent 💬 [1] Icosapent[2] Eicosapentaenoic acid; Icosapent; --[7] 8, 49, 96, 97, 296, 297, 338 💬
126 Inositol 💬 [1] Inositol[1] Inositol; --[2] 96, 97 💬
127 Vedolizumab 💬 [1] Vedolizumab[2] ENTYVIO; VEDOLIZUMAB; [2] ITGA4,
ITGB7 💬
[15] Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Human papillomavirus infection, Hypertrophic cardiomyopathy, Intestinal immune network for IgA production, Leishmaniasis, Leukocyte transendothelial migration, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Transcriptional misregulation in cancer, Yersinia infection 💬[3] 94, 96, 97 💬
128 Loperamide 💬 [1] Loperamide[2] LOPERAMIDE; Loperamide hydrochloride; [3] OPRD1,
OPRK1,
OPRM1 💬
[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[2] 13, 97 💬
129 Losartan 💬 [1] Losartan[3] Cozaar; Losartan; LOSARTAN POTASSIUM; [1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
130 Melatonin 💬 [1] Melatonin[2] Circadin; Melatonin; [2] MTNR1A,
MTNR1B 💬
[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬[12] 6, 8, 13, 37, 46, 49, 72, 78, 90, 97, 145, 202 💬
131 Melitracen 💬 [1] Melitracen[1] Melitracen; --[1] 97 💬
132 Neomycin 💬 [1] Neomycin[1] Neomycin; --[3] 96, 97, 296 💬
133 Oseltamivir 💬 [1] Oseltamivir[1] Oseltamivir; --[2] 97, 299 💬
134 Rosiglitazone 💬 [1] Rosiglitazone[2] Rosiglitazone; Rosiglitazone maleate; [1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[5] 46, 75, 97, 222, 265 💬
135 Rosuvastatin 💬 [1] Rosuvastatin[3] Crestor; Rosuvastatin; Rosuvastatin calcium; [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
136 Tacrolimus 💬 [1] Tacrolimus[2] Prograf; Tacrolimus; [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬
[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
137 Anrukinzumab 💬 [1] Anrukinzumab[1] Anrukinzumab; [1] IL13 💬[8] Asthma, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, IL-17 signaling pathway, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation 💬[1] 97 💬
138 Apremilast 💬 [1] Apremilast[2] Apremilast; Otezla; [4] PDE4A,
PDE4B,
PDE4C,
PDE4D 💬
[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[7] 46, 50, 56, 97, 107, 162, 271 💬
139 Baminercept 💬 [1] Baminercept[2] Baminercept; Baminercept alfa; [1] LTB 💬[3] Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[4] 13, 46, 53, 97 💬
140 Ferric carboxymaltose 💬 [1] Ferric carboxymaltose[1] Ferric carboxymaltose; --[4] 86, 96, 97, 299 💬
141 Ferric sulfate 💬 [1] Ferric sulfate[1] Stasis; --[2] 66, 97 💬
142 Myrrh 💬 [1] Myrrh[1] MYRRH; --[1] 97 💬
143 Raspberry 💬 [1] Raspberry[1] Raspberry; --[1] 97 💬
144 German chamomile flower 💬 [1] Chamomile[2] Chamomile; MATRICARIA FLOWER; --[2] 6, 97 💬
145 Ustekinumab 💬 [1] Ustekinumab[2] STELARA; Ustekinumab; [3] IL12A,
IL12B,
IL23A 💬
[28] African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬[16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
146 Linaclotide 💬 [1] Linaclotide[1] Linaclotide; [1] GUCY2C 💬[2] Metabolic pathways, Purine metabolism 💬[2] 6, 97 💬
147 Sotrastaurin 💬 [1] Sotrastaurin[1] Sotrastaurin; [4] PRKCD,
PRKCE,
PRKCH,
PRKCQ 💬
[29] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Aldosterone synthesis and secretion, Apelin signaling pathway, Autophagy - animal, C-type lectin receptor signaling pathway, Chemical carcinogenesis - reactive oxygen species, Chemokine signaling pathway, Diabetic cardiomyopathy, Estrogen signaling pathway, Fc gamma R-mediated phagocytosis, GnRH signaling pathway, Inflammatory mediator regulation of TRP channels, Insulin resistance, MicroRNAs in cancer, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Prion disease, Shigellosis, Sphingolipid signaling pathway, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 97 💬
148 Remestemcel-L 💬 [1] Remestemcel-L[3] Adult human mesenchymal stem cells; Prochymal; Remestemcel-L; --[3] 85, 96, 97 💬
149 Etrolizumab 💬 [1] Etrolizumab[1] ETROLIZUMAB; [1] ITGB7 💬[11] Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Human papillomavirus infection, Hypertrophic cardiomyopathy, Intestinal immune network for IgA production, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Transcriptional misregulation in cancer 💬[2] 96, 97 💬
150 Tofacitinib 💬 [1] Tofacitinib[4] Tasocitinib; Tofacitinib; XELJANZ; Xeljanz XR; [4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
151 Telotristat 💬 [1] Telotristat[1] Telotristat; [2] TPH1,
TPH2 💬
[4] Folate biosynthesis, Metabolic pathways, Serotonergic synapse, Tryptophan metabolism 💬[1] 97 💬
152 Tralokinumab 💬 [1] Tralokinumab[1] Tralokinumab; [1] IL13 💬[8] Asthma, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, IL-17 signaling pathway, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation 💬[2] 85, 97 💬
153 Nivolumab 💬 [1] Nivolumab[1] Nivolumab; [1] PDCD1 💬[3] Cell adhesion molecules, PD-L1 expression and PD-1 checkpoint pathway in cancer, T cell receptor signaling pathway 💬[12] 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
154 Dupilumab 💬 [1] Dupilumab[2] DUPILUMAB; Dupixent; [1] IL4R 💬[8] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Inflammatory bowel disease, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬[5] 51, 97, 98, 160, 162 💬
155 Guselkumab 💬 [1] Guselkumab[2] GUSELKUMAB; Tremfya; [1] IL23A 💬[9] C-type lectin receptor signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Pertussis, Rheumatoid arthritis, Th17 cell differentiation, Tuberculosis 💬[5] 37, 41, 51, 96, 97 💬
156 Bezlotoxumab 💬 [1] Bezlotoxumab[1] Bezlotoxumab; --[2] 96, 97 💬
157 Empagliflozin 💬 [1] Empagliflozin[2] Empagliflozin; Jardiance; [1] SLC5A2 💬[1] 💬[6] 58, 65, 67, 72, 97, 257 💬
158 Catridecacog 💬 [1] Catridecacog[1] Catridecacog; --[2] 97, 288 💬
159 Methylthioninium chloride hydrate 💬 [1] Methylene blue[2] METHYLENE BLUE; Methylthioninium chloride; --[2] 97, 127 💬
160 Abrilumab 💬 [1] Abrilumab[1] Abrilumab; [2] ITGA4,
ITGB7 💬
[15] Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Human papillomavirus infection, Hypertrophic cardiomyopathy, Intestinal immune network for IgA production, Leishmaniasis, Leukocyte transendothelial migration, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Transcriptional misregulation in cancer, Yersinia infection 💬[2] 96, 97 💬
161 Filgotinib 💬 [1] Filgotinib[2] FILGOTINIB; Jyseleca; [1] JAK1 💬[27] Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[6] 46, 53, 96, 97, 222, 271 💬
162 Amiselimod 💬 [1] Amiselimod[1] Amiselimod; [5] S1PR1,
S1PR2,
S1PR3,
S1PR4,
S1PR5 💬
[3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[1] 97 💬
163 Brazikumab 💬 [1] Brazikumab[1] BRAZIKUMAB; [1] IL23A 💬[9] C-type lectin receptor signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Pertussis, Rheumatoid arthritis, Th17 cell differentiation, Tuberculosis 💬[2] 96, 97 💬
164 Cannabidiol 💬 [1] Cannabidiol[4] CANNABIDIOL; Epidiolex; Epidyolex; SATIVEX; [2] CNR1,
CNR2 💬
[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[19] 2, 6, 8, 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
165 Etrasimod 💬 [1] Etrasimod[1] Etrasimod; [5] S1PR1,
S1PR2,
S1PR3,
S1PR4,
S1PR5 💬
[3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[3] 96, 97, 98 💬
166 Itacitinib 💬 [1] Itacitinib[1] Itacitinib; [1] JAK1 💬[27] Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[4] 46, 51, 97, 228 💬
167 Mongersen 💬 [1] Mongersen[1] Mongersen; [1] SMAD7 💬[2] Hippo signaling pathway, TGF-beta signaling pathway 💬[2] 96, 97 💬
168 Ozanimod 💬 [1] Ozanimod[2] Ozanimod; Zeposia; [5] S1PR1,
S1PR2,
S1PR3,
S1PR4,
S1PR5 💬
[3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[3] 13, 96, 97 💬
169 Upadacitinib 💬 [1] Upadacitinib[2] Rinvoq; Upadacitinib; [1] JAK1 💬[27] Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[8] 40, 41, 46, 49, 96, 97, 107, 271 💬
170 Vamorolone 💬 [1] Vamorolone[1] VAMOROLONE; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[2] 97, 113 💬
171 Risankizumab 💬 [1] Risankizumab[1] RISANKIZUMAB; [1] IL23A 💬[9] C-type lectin receptor signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Pertussis, Rheumatoid arthritis, Th17 cell differentiation, Tuberculosis 💬[4] 37, 96, 97, 271 💬
172 Mirikizumab 💬 [1] Mirikizumab[1] MIRIKIZUMAB; [1] IL23A 💬[9] C-type lectin receptor signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Pertussis, Rheumatoid arthritis, Th17 cell differentiation, Tuberculosis 💬[3] 37, 96, 97 💬
173 Bimekizumab 💬 [1] Bimekizumab[1] Bimekizumab; [2] IL17A,
IL17F 💬
[6] Alcoholic liver disease, Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Inflammatory bowel disease, Rheumatoid arthritis, Th17 cell differentiation 💬[3] 46, 97, 271 💬
174 Ravagalimab 💬 [1] Ravagalimab[1] Ravagalimab; [1] CD40 💬[17] Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecules, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Human T-cell leukemia virus 1 infection, Intestinal immune network for IgA production, Lipid and atherosclerosis, Malaria, NF-kappa B signaling pathway, Primary immunodeficiency, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Viral myocarditis 💬[2] 53, 97 💬
175 Efavaleukin alfa 💬 [1] Efavaleukin alfa[1] EFAVALEUKIN ALFA; --[2] 49, 97 💬
176 Deucravacitinib 💬 [1] Deucravacitinib[1] Deucravacitinib; [1] TYK2 💬[16] Coronavirus disease - COVID-19, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis 💬[3] 49, 96, 97 💬
177 Efmarodocokin alfa 💬 [1] Efmarodocokin alfa[2] Efmarodocokin alfa; IL-22Fc; [1] IL22 💬[4] Cytokine-cytokine receptor interaction, Inflammatory bowel disease, JAK-STAT signaling pathway, Th17 cell differentiation 💬[2] 96, 97 💬
178 Spesolimab 💬 [1] Spesolimab[1] SPESOLIMAB; [1] IL1RL2 💬[1] Cytokine-cytokine receptor interaction 💬[3] 37, 96, 97 💬
179 Cobitolimod 💬 [1] Cobitolimod[1] COBITOLIMOD; [1] TLR9 💬[9] African trypanosomiasis, Chagas disease, Herpes simplex virus 1 infection, Malaria, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Salmonella infection, Toll-like receptor signaling pathway, Tuberculosis 💬[1] 97 💬