Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1Amitriptyline, fluoxetine and tramadol alone (control group)
(D08623)		3件: Amitriptyline,
Fluoxetine,
Tramadol		3件: Fluoxetine ,
Amitriptyline ,
Tramadol (D08623) 💬 		3件: OPRM1,
SLC6A2,
SLC6A4 💬 		5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬1件: 78 💬
2Sc recombinant growth hormone + amitriptyline, fluoxetine and tramadol (treated group)
(D08623)		4件: Amitriptyline,
Fluoxetine,
Somatotropin,
Tramadol		3件: Fluoxetine ,
Amitriptyline ,
Tramadol (D08623) 💬 		3件: OPRM1,
SLC6A2,
SLC6A4 💬 		5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬1件: 78 💬
3Tramadol
(D08623)		1件: Tramadol1件: Tramadol (D08623) 💬 1件: OPRM1 💬 3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬5件: 46, 70, 78, 226, 271 💬
4Tramadol /acetaminophen
(D08623)		2件: Acetaminophen,
Tramadol		2件: Acetaminophen ,
Tramadol (D08623) 💬 		3件: OPRM1,
PTGS1,
PTGS2 💬 		26件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Estrogen signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, Morphine addiction, NF-kappa B signaling pathway, Neuroactive ligand-receptor interaction, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 271 💬
5Tramadol hydrochloride + acetaminophen
(D08623)		2件: Acetaminophen,
Tramadol		2件: Acetaminophen ,
Tramadol (D08623) 💬 		3件: OPRM1,
PTGS1,
PTGS2 💬 		26件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Estrogen signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, Morphine addiction, NF-kappa B signaling pathway, Neuroactive ligand-receptor interaction, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 46 💬
6Tramadol with ropivacaine
(D08623)		2件: Ropivacaine,
Tramadol		2件: Ropivacaine ,
Tramadol (D08623) 💬 		6件: OPRM1,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		6件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction 💬1件: 70 💬