Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Human cytomegalovirus infection 💬
1件: CASP9 💬 D11195 💬 Rimiducid 6件: 19, 60, 65, 284, 285, 326 💬
2 Human cytomegalovirus infection 💬
4件: CCL2, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
3 Human cytomegalovirus infection 💬
1件: CCR5 💬 D09878 💬 Cenicriviroc 1件: 94 💬
4 Human cytomegalovirus infection 💬
1件: CCR5 💬 D06670 💬 Maraviroc 2件: 46, 84 💬
5 Human cytomegalovirus infection 💬
2件: CDK4, CDK6 💬 D10688 💬 Abemaciclib 1件: 34 💬
6 Human cytomegalovirus infection 💬
1件: CXCR2 💬 D08984 💬 Reparixin 2件: 298, 299 💬
7 Human cytomegalovirus infection 💬
1件: CXCR4 💬 D08971 💬 Plerixafor 6件: 19, 20, 51, 65, 285, 299 💬
8 Human cytomegalovirus infection 💬
1件: EGFR 💬 D03455 💬 Cetuximab 5件: 34, 51, 86, 89, 331 💬
9 Human cytomegalovirus infection 💬
1件: EGFR 💬 D04023 💬 Erlotinib 1件: 94 💬
10 Human cytomegalovirus infection 💬
1件: EGFR 💬 D07907 💬 Erlotinib 1件: 94 💬
11 Human cytomegalovirus infection 💬
1件: EGFR 💬 D01977 💬 Gefitinib 1件: 75 💬
12 Human cytomegalovirus infection 💬
1件: EGFR 💬 D11251 💬 Icotinib 1件: 34 💬
13 Human cytomegalovirus infection 💬
1件: EGFR 💬 D04024 💬 Lapatinib 3件: 34, 74, 75 💬
14 Human cytomegalovirus infection 💬
1件: EGFR 💬 D08108 💬 Lapatinib 3件: 34, 74, 75 💬
15 Human cytomegalovirus infection 💬
1件: EGFR 💬 D11772 💬 Tesevatinib 1件: 67 💬
16 Human cytomegalovirus infection 💬
6件: HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G 💬 D04318 💬 Glatiramer 4件:  2 , 13, 96, 156 💬
17 Human cytomegalovirus infection 💬
13件: IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 D09662 💬 Rontalizumab 1件: 49 💬
18 Human cytomegalovirus infection 💬
13件: IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 D09668 💬 Sifalimumab 1件: 49 💬
19 Human cytomegalovirus infection 💬
1件: IL1B 💬 D09315 💬 Canakinumab 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
20 Human cytomegalovirus infection 💬
1件: IL1B 💬 D09911 💬 Gevokizumab 4件: 41, 50, 56, 269 💬
21 Human cytomegalovirus infection 💬
1件: IL1B 💬 D06635 💬 Rilonacept 4件: 51, 106, 107, 266 💬
22 Human cytomegalovirus infection 💬
1件: IL1R1 💬 D02934 💬 Anakinra 19件:  2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
23 Human cytomegalovirus infection 💬
1件: IL6 💬 D09669 💬 Siltuximab 2件: 28, 331 💬
24 Human cytomegalovirus infection 💬
1件: IL6 💬 D10080 💬 Sirukumab 2件: 41, 46 💬
25 Human cytomegalovirus infection 💬
2件: IL6, TNF 💬 D08976 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
26 Human cytomegalovirus infection 💬
1件: IL6R 💬 D10161 💬 Sarilumab 5件: 41, 46, 84, 107, 271 💬
27 Human cytomegalovirus infection 💬
1件: IL6R 💬 D11079 💬 Satralizumab 2件: 11, 13 💬
28 Human cytomegalovirus infection 💬
1件: IL6R 💬 D02596 💬 Tocilizumab 21件:  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
29 Human cytomegalovirus infection 💬
1件: JAK1 💬 D10308 💬 Baricitinib 13件: 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
30 Human cytomegalovirus infection 💬
1件: JAK1 💬 D10871 💬 Filgotinib 6件: 46, 53, 96, 97, 222, 271 💬
31 Human cytomegalovirus infection 💬
1件: JAK1 💬 D10944 💬 Itacitinib 5件: 46, 51, 60, 97, 228 💬
32 Human cytomegalovirus infection 💬
1件: JAK1 💬 D10653 💬 Peficitinib 1件: 46 💬
33 Human cytomegalovirus infection 💬
1件: JAK1 💬 D09959 💬 Ruxolitinib 1件: 228 💬
34 Human cytomegalovirus infection 💬
1件: JAK1 💬 D09970 💬 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
35 Human cytomegalovirus infection 💬
1件: JAK1 💬 D10994 💬 Upadacitinib 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
36 Human cytomegalovirus infection 💬
2件: MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib 1件: 34 💬
37 Human cytomegalovirus infection 💬
2件: MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib 1件: 280 💬
38 Human cytomegalovirus infection 💬
2件: MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib 1件: 34 💬
39 Human cytomegalovirus infection 💬
2件: MAP2K1, MAP2K2 💬 D10175 💬 Trametinib 4件:  2 , 34, 279, 280 💬
40 Human cytomegalovirus infection 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod 2件: 113, 222 💬
41 Human cytomegalovirus infection 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod 1件:  8  💬
42 Human cytomegalovirus infection 💬
1件: MTOR 💬 D02714 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
43 Human cytomegalovirus infection 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
44 Human cytomegalovirus infection 💬
1件: MTOR 💬 D06068 💬 Temsirolimus 4件: 13, 34, 89, 331 💬
45 Human cytomegalovirus infection 💬
1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
46 Human cytomegalovirus infection 💬
1件: PDGFRA 💬 D01441 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
47 Human cytomegalovirus infection 💬
1件: PDGFRA 💬 D08066 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
48 Human cytomegalovirus infection 💬
1件: PDGFRA 💬 D08953 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬
49 Human cytomegalovirus infection 💬
1件: PDGFRA 💬 D10481 💬 Nintedanib 5件: 51, 85, 89, 227, 228 💬
50 Human cytomegalovirus infection 💬
1件: PDGFRA 💬 D06402 💬 Sunitinib 2件: 28, 34 💬
51 Human cytomegalovirus infection 💬
1件: PDGFRA 💬 D08552 💬 Sunitinib 2件: 28, 34 💬
52 Human cytomegalovirus infection 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
53 Human cytomegalovirus infection 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
54 Human cytomegalovirus infection 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
55 Human cytomegalovirus infection 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D05480 💬 Pimecrolimus 1件: 160 💬
56 Human cytomegalovirus infection 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
57 Human cytomegalovirus infection 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
58 Human cytomegalovirus infection 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D09033 💬 Voclosporin 1件: 222 💬
59 Human cytomegalovirus infection 💬
1件: PTGER1 💬 D00180 💬 Alprostadil 2件: 51, 70 💬
60 Human cytomegalovirus infection 💬
1件: PTGER1 💬 D02705 💬 Alprostadil 2件: 51, 70 💬
61 Human cytomegalovirus infection 💬
1件: PTGER1 💬 D02722 💬 Limaprost 1件: 70 💬
62 Human cytomegalovirus infection 💬
3件: PTGER2, PTGER3, PTGER4 💬 D00419 💬 Misoprostol 3件: 46, 70, 271 💬
63 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D01545 💬 Aceclofenac 1件: 46 💬
64 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D00217 💬 Acetaminophen 18件:  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬
65 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D00109 💬 Acetylsalicylic acid 15件: 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬
66 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D00567 💬 Celecoxib 10件:  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
67 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D00903 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
68 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D00904 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
69 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D07816 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
70 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D00130 💬 Diflunisal 1件: 28 💬
71 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D00315 💬 Etodolac 1件: 46 💬
72 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D03710 💬 Etoricoxib 2件: 46, 271 💬
73 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D00330 💬 Flurbiprofen 3件: 13, 21, 46 💬
74 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D01475 💬 Flurbiprofen 3件: 13, 21, 46 💬
75 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D02290 💬 Flurbiprofen 3件: 13, 21, 46 💬
76 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D00126 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬
77 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D01122 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬
78 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D04490 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬
79 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D06606 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬
80 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D00141 💬 Indomethacin 3件: 225, 271, 298 💬
81 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D01565 💬 Indomethacin 3件: 225, 271, 298 💬
82 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D02110 💬 Indomethacin 3件: 225, 271, 298 💬
83 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D00132 💬 Ketoprofen 1件: 46 💬
84 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D00813 💬 Ketorolac 2件: 70, 226 💬
85 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D08104 💬 Ketorolac 2件: 70, 226 💬
86 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D08149 💬 Loxoprofen 2件: 46, 271 💬
87 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D03714 💬 Lumiracoxib 1件: 46 💬
88 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D00969 💬 Meloxicam 4件: 46, 49, 271, 296 💬
89 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D00118 💬 Naproxen 4件: 13, 46, 107, 271 💬
90 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D01049 💬 Nimesulide 1件: 46 💬
91 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D03716 💬 Parecoxib 2件: 46, 271 💬
92 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D00568 💬 Rofecoxib 1件: 46 💬
93 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D00428 💬 Salsalate 1件:  5  💬
94 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D00120 💬 Sulindac 1件: 206 💬
95 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D01183 💬 Tolfenamic acid 1件:  5  💬
96 Human cytomegalovirus infection 💬
1件: PTGS2 💬 D02709 💬 Valdecoxib 1件: 46 💬
97 Human cytomegalovirus infection 💬
1件: RAF1 💬 D06272 💬 Sorafenib 2件: 34, 86 💬
98 Human cytomegalovirus infection 💬
1件: RAF1 💬 D08524 💬 Sorafenib 2件: 34, 86 💬
99 Human cytomegalovirus infection 💬
1件: RELA 💬 D12181 💬 Edasalonexent 1件: 113 💬
100 Human cytomegalovirus infection 💬
2件: ROCK1, ROCK2 💬 D07941 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
101 Human cytomegalovirus infection 💬
1件: ROCK2 💬 D11815 💬 Belumosudil 1件: 51 💬
102 Human cytomegalovirus infection 💬
1件: SRC 💬 D03252 💬 Bosutinib 2件:  2 , 67 💬
103 Human cytomegalovirus infection 💬
1件: SRC 💬 D03658 💬 Dasatinib 2件: 51, 85 💬
104 Human cytomegalovirus infection 💬
1件: SRC 💬 D06414 💬 Dasatinib 2件: 51, 85 💬
105 Human cytomegalovirus infection 💬
1件: SRC 💬 D09664 💬 Saracatinib 3件:  6 , 89, 272 💬
106 Human cytomegalovirus infection 💬
1件: TNF 💬 D02597 💬 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
107 Human cytomegalovirus infection 💬
1件: TNF 💬 D03441 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
108 Human cytomegalovirus infection 💬
1件: TNF 💬 D00742 💬 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
109 Human cytomegalovirus infection 💬
1件: TNF 💬 D04358 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
110 Human cytomegalovirus infection 💬
1件: TNF 💬 D02598 💬 Infliximab 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
111 Human cytomegalovirus infection 💬
1件: TNF 💬 D04687 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
112 Human cytomegalovirus infection 💬
1件: TNF 💬 D09944 💬 Ozoralizumab 1件: 46 💬
113 Human cytomegalovirus infection 💬
1件: TNF 💬 D05393 💬 Pegsunercept 1件: 46 💬
114 Human cytomegalovirus infection 💬
1件: TNF 💬 D00754 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
115 Human cytomegalovirus infection 💬
1件: VEGFA 💬 D09574 💬 Aflibercept 2件: 90, 166 💬
116 Human cytomegalovirus infection 💬
1件: VEGFA 💬 D06409 💬 Bevacizumab 9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
117 Human cytomegalovirus infection 💬
1件: VEGFA 💬 D05697 💬 Ranibizumab 4件: 34, 166, 227, 301 💬