Target Gene/Pathway PATHWAY / GENE


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No. KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG DRUG DrugBank 指定難病告示番号
1 DDC 9件: Tyrosine metabolism 💬, Phenylalanine metabolism 💬, Tryptophan metabolism 💬, Metabolic pathways 💬, Serotonergic synapse 💬, Dopaminergic synapse 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Alcoholism 💬 D00558 Carbidopa 9件: 2, 4, 6, 13, 17, 90, 140, 164, 201
2 DRD1 10件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Gap junction 💬, Dopaminergic synapse 💬, Parkinson disease 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Morphine addiction 💬, Alcoholism 💬 D00059 Levodopa 8件: 2, 4, 6, 17, 90, 140, 164, 201
3 DRD2 8件: Rap1 signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Gap junction 💬, Dopaminergic synapse 💬, Parkinson disease 💬, Cocaine addiction 💬, Alcoholism 💬 D00059 Levodopa 8件: 2, 4, 6, 17, 90, 140, 164, 201
4 DRD3 2件: Neuroactive ligand-receptor interaction 💬, Dopaminergic synapse 💬 D00059 Levodopa 8件: 2, 4, 6, 17, 90, 140, 164, 201
5 DRD4 2件: Neuroactive ligand-receptor interaction 💬, Dopaminergic synapse 💬 D00059 Levodopa 8件: 2, 4, 6, 17, 90, 140, 164, 201
6 DRD5 4件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Dopaminergic synapse 💬 D00059 Levodopa 8件: 2, 4, 6, 17, 90, 140, 164, 201
7 GABRA1 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D04282 Gaboxadol 2件: 201, 206
8 GABRA2 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D04282 Gaboxadol 2件: 201, 206
9 GABRA3 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D04282 Gaboxadol 2件: 201, 206
10 GABRA4 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D04282 Gaboxadol 2件: 201, 206
11 GABRA5 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D04282 Gaboxadol 2件: 201, 206
12 GABRA6 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D04282 Gaboxadol 2件: 201, 206
13 GABRB1 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D04282 Gaboxadol 2件: 201, 206
14 GABRB2 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D04282 Gaboxadol 2件: 201, 206
15 GABRB3 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D04282 Gaboxadol 2件: 201, 206
16 GABRD 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D04282 Gaboxadol 2件: 201, 206
17 GABRE 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D04282 Gaboxadol 2件: 201, 206
18 GABRG1 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D04282 Gaboxadol 2件: 201, 206
19 GABRG2 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D04282 Gaboxadol 2件: 201, 206
20 GABRG3 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D04282 Gaboxadol 2件: 201, 206
21 GABRP 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D04282 Gaboxadol 2件: 201, 206
22 GABRQ 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D04282 Gaboxadol 2件: 201, 206