Target Gene/Pathway Pathway / Gene


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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 ABCD1 💬 2件: ABC transporters, Peroxisome Elivaldogene autotemcel 💬 Elivaldogene autotemcel 1件: 20 💬
2 HAO1 💬 4件: Glyoxylate and dicarboxylate metabolism, Metabolic pathways, Carbon metabolism, Peroxisome Lumasiran 💬 Lumasiran 1件: 234 💬
3 PPARA 💬
(Full name: peroxisome proliferator activated receptor alpha)
10件: PPAR signaling pathway, cAMP signaling pathway, Adipocytokine signaling pathway, Glucagon signaling pathway, Insulin resistance, Non-alcoholic fatty liver disease, Alcoholic liver disease, Hepatitis C, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy Fenofibrate 💬 Fenofibrate 6件: 8, 79, 93, 94, 97, 265 💬
4 PPARA 💬
(Full name: peroxisome proliferator activated receptor alpha)
10件: PPAR signaling pathway, cAMP signaling pathway, Adipocytokine signaling pathway, Glucagon signaling pathway, Insulin resistance, Non-alcoholic fatty liver disease, Alcoholic liver disease, Hepatitis C, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy Bezafibrate 💬 Bezafibrate 7件: 20, 93, 94, 160, 296, 316, 324 💬
5 PPARA 💬
(Full name: peroxisome proliferator activated receptor alpha)
10件: PPAR signaling pathway, cAMP signaling pathway, Adipocytokine signaling pathway, Glucagon signaling pathway, Insulin resistance, Non-alcoholic fatty liver disease, Alcoholic liver disease, Hepatitis C, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy Pemafibrate 💬 Pemafibrate 1件: 93 💬
6 PPARA 💬
(Full name: peroxisome proliferator activated receptor alpha)
10件: PPAR signaling pathway, cAMP signaling pathway, Adipocytokine signaling pathway, Glucagon signaling pathway, Insulin resistance, Non-alcoholic fatty liver disease, Alcoholic liver disease, Hepatitis C, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy Elafibranor 💬 Elafibranor 2件: 93, 94 💬
7 PPARG 💬
(Full name: peroxisome proliferator activated receptor gamma)
11件: PPAR signaling pathway, AMPK signaling pathway, Longevity regulating pathway, Osteoclast differentiation, Thermogenesis, Non-alcoholic fatty liver disease, Huntington disease, Pathways in cancer, Transcriptional misregulation in cancer, Thyroid cancer, Lipid and atherosclerosis Pioglitazone 💬 Pioglitazone 17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
8 PPARG 💬
(Full name: peroxisome proliferator activated receptor gamma)
11件: PPAR signaling pathway, AMPK signaling pathway, Longevity regulating pathway, Osteoclast differentiation, Thermogenesis, Non-alcoholic fatty liver disease, Huntington disease, Pathways in cancer, Transcriptional misregulation in cancer, Thyroid cancer, Lipid and atherosclerosis Rosiglitazone 💬 Rosiglitazone 5件: 46, 75, 97, 222, 265 💬
9 PPARG 💬
(Full name: peroxisome proliferator activated receptor gamma)
11件: PPAR signaling pathway, AMPK signaling pathway, Longevity regulating pathway, Osteoclast differentiation, Thermogenesis, Non-alcoholic fatty liver disease, Huntington disease, Pathways in cancer, Transcriptional misregulation in cancer, Thyroid cancer, Lipid and atherosclerosis Seladelpar 💬 Seladelpar 2件: 93, 94 💬
10 PPARG 💬
(Full name: peroxisome proliferator activated receptor gamma)
11件: PPAR signaling pathway, AMPK signaling pathway, Longevity regulating pathway, Osteoclast differentiation, Thermogenesis, Non-alcoholic fatty liver disease, Huntington disease, Pathways in cancer, Transcriptional misregulation in cancer, Thyroid cancer, Lipid and atherosclerosis Leriglitazone 💬 Leriglitazone 1件: 20 💬
11 PPARG 💬
(Full name: peroxisome proliferator activated receptor gamma)
11件: PPAR signaling pathway, AMPK signaling pathway, Longevity regulating pathway, Osteoclast differentiation, Thermogenesis, Non-alcoholic fatty liver disease, Huntington disease, Pathways in cancer, Transcriptional misregulation in cancer, Thyroid cancer, Lipid and atherosclerosis Bocidelpar 💬 Bocidelpar 1件: 113 💬
12 SOD1 💬 8件: Peroxisome, Longevity regulating pathway - multiple species, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - reactive oxygen species Tofersen 💬 Tofersen 1件: 2 💬
13 XDH 💬 6件: Purine metabolism, Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Peroxisome Allopurinol 💬 Allopurinol 7件: 6, 46, 57, 60, 66, 96, 97 💬
14 XDH 💬 6件: Purine metabolism, Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Peroxisome Febuxostat 💬 Febuxostat 3件: 2, 6, 13 💬