Drug Description in Trials / DrugBank / KEGG DRUG


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No. DrugBank 薬物名(臨床試験情報から抽出) KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes
指定難病告示番号
1 Saccharomyces cerevisiae 1件: Saccharomyces---1件: 51
2 Sacubitril 2件: Entresto; Sacubitril1件: D10225 1件: MME 💬4件: Alzheimer disease, Hematopoietic cell lineage, Protein digestion and absorption, Renin-angiotensin system 💬1件: 58
3 Safinamide 3件: Safinamida; SAFINAMIDE; Xadago1件: D10158 1件: MAOB 💬14件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬2件: 6, 17
4 Sage 1件: Sage---1件: 6
5 Salbutamol 3件: Albuterol; Salbutamol; Ventolin1件: D02147 1件: ADRB2 💬9件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬14件: 3, 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299
6 Salicylic acid 2件: 2-Hydroxybenzoic acid; Salicylic acid1件: D00097 --1件: 97
7 Salmeterol 1件: Salmeterol2件: D00687 ,
D05792
1件: ADRB2 💬9件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 299
8 Salmon, unspecified 1件: Salmon---3件: 96, 97, 225
9 Salsalate 1件: Salsalate1件: D00428 2件: PTGS1,
PTGS2 💬
23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 5
10 Sapropterin 5件: 6R-BH4; KUVAN; Sapropterin; SAPROPTERIN DIHYDROCHLORIDE; Tetrahydrobiopterin1件: D08505 --5件: 51, 86, 124, 240, 299
11 Saquinavir 1件: Saquinavir2件: D00429 ,
D01160
--2件: 86, 265
12 Saracatinib 1件: Saracatinib1件: D09664 2件: ABL1,
SRC 💬
49件: Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, C-type lectin receptor signaling pathway, Cell cycle, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, GnRH signaling pathway, Hepatitis B, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MicroRNAs in cancer, Mitophagy - animal, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Prolactin signaling pathway, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬3件: 6, 89, 272
13 Sarcosine 1件: Sarcosine---1件: 6
14 Sargramostim 2件: Leukine; Sargramostim1件: D05803 1件: CSF2RA 💬4件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬7件: 6, 28, 60, 62, 96, 229, 285
15 Sarilumab 4件: Kevzara; REGN88; SAR153191; Sarilumab1件: D10161 1件: IL6R 💬12件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬5件: 41, 46, 84, 107, 271
16 Sarizotan 1件: SARIZOTAN---2件: 6, 156
17 Saroglitazar 1件: Saroglitazar---1件: 93
18 SARS-CoV-2 mRNA vaccine 1件: SARS-COV-2 mRNA Vaccine---1件: 13
19 Satavaptan 1件: Satavaptan---1件: 72
20 Satralizumab 2件: Enspryng; SATRALIZUMAB1件: D11079 1件: IL6R 💬12件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬2件: 11, 13
21 Saxagliptin 1件: Saxagliptin1件: D08996 1件: DPP4 💬1件: Protein digestion and absorption 💬1件: 299
22 SC12267 1件: SC12267---3件: 46, 96, 97
23 Scopolamine 1件: Scopolamine1件: D00138 5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬
13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬1件: 2
24 SCYX-7158 1件: SCYX-7158---1件: 65
25 Sebelipase alfa 4件: KANUMA; SBC-102; Sebelipasa Alfa; Sebelipase Alfa1件: D10377 1件: LIPA 💬3件: Cholesterol metabolism, Lysosome, Steroid biosynthesis 💬1件: 19
26 Secretin human 3件: Human Secretin; Secretin; Synthetic human secretin---1件: 298
27 Secukinumab 2件: COSENTYX; SECUKINUMAB1件: D09967 1件: IL17A 💬6件: Alcoholic liver disease, Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Inflammatory bowel disease, Rheumatoid arthritis, Th17 cell differentiation 💬8件: 13, 37, 41, 46, 107, 160, 269, 271
28 Seladelpar 1件: SELADELPAR1件: D11256 1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬2件: 93, 94
29 Selegiline 2件: SELEGILINE; Zelapar2件: D00785 ,
D03731
1件: MAOB 💬14件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬1件: 6
30 Selenium 1件: SELENIUM---4件: 13, 96, 278, 298
31 Selexipag 2件: SELEXIPAG; Uptravi1件: D09994 1件: PTGIR 💬3件: Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬6件: 47, 51, 70, 84, 86, 88
32 Seliciclib 2件: R-roscovitine; Seliciclib---2件: 75, 299
33 Selinexor 1件: Selinexor1件: D11222 1件: XPO1 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Nucleocytoplasmic transport, Ribosome biogenesis in eukaryotes 💬1件: 28
34 Selisistat 1件: Selisistat---1件: 8
35 Selonsertib 1件: Selonsertib1件: D10988 1件: MAP3K5 💬20件: Alcoholic liver disease, Alzheimer disease, Amyotrophic lateral sclerosis, Apoptosis, Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Huntington disease, Lipid and atherosclerosis, MAPK signaling pathway, Neurotrophin signaling pathway, Non-alcoholic fatty liver disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Platinum drug resistance, Protein processing in endoplasmic reticulum, Sphingolipid signaling pathway, Spinocerebellar ataxia, TNF signaling pathway, Thermogenesis, Tight junction 💬1件: 86
36 Selumetinib 2件: Koselugo; Selumetinib1件: D09666 2件: MAP2K1,
MAP2K2 💬
89件: Acute myeloid leukemia, Alcoholism, Alzheimer disease, Apelin signaling pathway, Apoptosis, Autophagy - animal, B cell receptor signaling pathway, Bladder cancer, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, Insulin signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Serotonergic synapse, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid cancer, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, VEGF signaling pathway, Vascular smooth muscle contraction, Yersinia infection, cAMP signaling pathway, cGMP-PKG signaling pathway, mTOR signaling pathway 💬1件: 34
37 Semaglutide 1件: Semaglutide1件: D10025 1件: GLP1R 💬3件: Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬1件: 6
38 Semapimod 1件: Semapimod---1件: 96
39 Senna leaf 1件: Senna1件: D06751 --1件: 291
40 SEP-363856 1件: SEP-363856---1件: 6
41 Serine 2件: L-Serine; Serine1件: D00016 --4件: 2, 6, 86, 96
42 Serlopitant 1件: Serlopitant1件: D09378 1件: TACR1 💬2件: Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬1件: 36
43 Serotonin 1件: Serotonin---3件: 2, 96, 97
44 Sertraline 1件: Sertraline2件: D00825 ,
D02360
1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬2件: 6, 206
45 Sesame oil 1件: Sesame oil1件: D03314 --1件: 3
46 Setmelanotide 1件: Setmelanotide1件: D11927 1件: MC4R 💬1件: Neuroactive ligand-receptor interaction 💬2件: 202, 265
47 Setrusumab 1件: Setrusumab---1件: 274
48 Sevelamer 1件: Sevelamer3件: D01983 ,
D06642 ,
D08512
--2件: 235, 238
49 Sevoflurane 1件: Sevoflurane1件: D00547 --7件: 6, 21, 22, 34, 98, 225, 296
50 Sibofimloc 1件: Sibofimloc1件: D11825 --1件: 96
51 Sifalimumab 1件: Sifalimumab1件: D09668 13件: IFNA1,
IFNA10,
IFNA13,
IFNA14,
IFNA16,
IFNA17,
IFNA2,
IFNA21,
IFNA4,
IFNA5,
IFNA6,
IFNA7,
IFNA8 💬
25件: Alcoholic liver disease, Autoimmune thyroid disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, PI3K-Akt signaling pathway, Pathways in cancer, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway, Tuberculosis 💬1件: 49
52 Sildenafil 6件: Mysildecard; Revatio; Sildenafil; SILDENAFIL CITRATE; SILDENAFILO; Viagra2件: D02229 ,
D08514
1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬17件: 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301
53 Silicon 1件: Silicon---1件: 6
54 Silodosin 2件: Silodosin; Silodyx1件: D01965 1件: ADRA1A 💬7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬2件: 6, 13
55 Siltuximab 1件: SILTUXIMAB1件: D09669 1件: IL6 💬51件: AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alcoholic liver disease, Alzheimer disease, Amoebiasis, Antifolate resistance, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Malaria, Measles, NOD-like receptor signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Tuberculosis, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection 💬2件: 28, 331
56 Silver 1件: Silver---2件: 35, 162
57 Simethicone 1件: Simethicone1件: D05841 --2件: 13, 96
58 Simtuzumab 2件: GS-6624; Simtuzumab---2件: 85, 94
59 Simvastatin 3件: SIMVASTATIN; Simvastatina; Simvastatine1件: D00434 1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬21件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310
60 Sinecatechins 1件: Veregen1件: D08997 --1件: 160
61 Siponimod 2件: Mayzent; SIPONIMOD1件: D11460 2件: S1PR1,
S1PR5 💬
3件: FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬2件: 13, 50
62 Sirolimus 3件: Rapamune; Rapamycin; SIROLIMUS1件: D00753 1件: MTOR 💬51件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬41件: 2, 6, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
63 Sirukumab 1件: Sirukumab1件: D10080 1件: IL6 💬51件: AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alcoholic liver disease, Alzheimer disease, Amoebiasis, Antifolate resistance, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Malaria, Measles, NOD-like receptor signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Tuberculosis, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection 💬2件: 41, 46
64 Sitagliptin 1件: Sitagliptin1件: D08516 1件: DPP4 💬1件: Protein digestion and absorption 💬4件: 6, 75, 233, 299
65 Sitaxentan 3件: Sitaxentan; Sitaxsentan; Thelin1件: D07171 1件: EDNRA 💬7件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86
66 Sivelestat 1件: Sivelestat1件: D03788 1件: ELANE 💬3件: Neutrophil extracellular trap formation, Systemic lupus erythematosus, Transcriptional misregulation in cancer 💬3件: 13, 85, 96
67 Smilagenin 1件: SMILAGENIN---1件: 6
68 Sobetirome 1件: Sobetirome1件: D09381 1件: THRB 💬2件: Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬1件: 20
69 SOBI-003 0件: ---1件: 19
70 Sodium acetate 1件: Sodium acetate1件: D01779 --1件: 81
71 Sodium aurothiomalate 1件: Sodium aurothiomalate1件: D00992 --1件: 46
72 Sodium bicarbonate 1件: Sodium Bicarbonate1件: D01203 --1件: 299
73 Sodium chloride 6件: Lactated Ringers; Natriumchlorid; REBIF; Saline; Sodium Chloride; Sporanox1件: D02056 --21件: 6, 11, 13, 14, 34, 46, 50, 51, 53, 60, 65, 67, 78, 96, 168, 193, 227, 228, 271, 288, 299
74 Sodium citrate 1件: Sodium citrate2件: D01781 ,
D05855
--4件: 67, 214, 215, 235
75 Sodium fluoride 2件: Beam; Sodium fluoride1件: D00943 --1件: 51
76 Sodium glycerophosphate 1件: Smofkabiven1件: D10489 --1件: 66
77 Sodium iodide 1件: Sodium iodide3件: D04874 ,
D05328 ,
D05863
--1件: 34
78 Sodium lauryl sulfate 0件: 1件: D01045 --1件: 2
79 Sodium nitrate 1件: Sodium Nitrate---2件: 58, 113
80 Sodium oxybate 1件: Sodium Oxybate1件: D05866 --2件: 6, 149
81 Sodium sulfate 1件: Sodium sulfate1件: D05877 --1件: 28
82 Sodium tetradecyl sulfate 0件: 1件: D06882 --2件: 50, 51
83 Sofosbuvir 2件: Harvoni; Sofosbuvir1件: D10366 --2件: 19, 254
84 Solifenacin 2件: Solifenacin; Solifenacin Succinate2件: D01269 ,
D08522
1件: CHRM3 💬11件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬3件: 6, 13, 53
85 Somapacitan 1件: SOMAPACITAN1件: D11194 1件: GHR 💬5件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬1件: 78
86 Somatorelin 2件: GHRH; Somatorelin1件: D08523 1件: GHRHR 💬2件: Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction 💬2件: 13, 78
87 Somatostatin 1件: Somatostatin1件: D07431 5件: SSTR1,
SSTR2,
SSTR3,
SSTR4,
SSTR5 💬
4件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬2件: 67, 78
88 Somatotropin 17件: Genotropin; Growth hormone; Human growth hormone; Humatrope; Norditropin; Norditropin SimpleXx; NUTROPIN; Nutropin AQ; NutropinAq; OMNITROPE; RECOMBINANT HUMAN GROWTH HORMONE; RhGH; SAIZEN; Somatotropin; Somatropin; SOMATROPINA; Zomacton1件: D02691 1件: GHR 💬5件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬23件: 2, 3, 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299
89 Somatrogon 1件: Somatrogon1件: D10990 --1件: 78
90 Somatropin pegol 1件: NNC126-0083---1件: 78
91 Somavaratan 1件: Somavaratan1件: D11193 1件: GHR 💬5件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬1件: 78
92 Sonlicromanol 1件: Sonlicromanol---1件: 21
93 Sorafenib 2件: Nexavar; Sorafenib2件: D06272 ,
D08524
8件: BRAF,
FLT3,
FLT4,
KDR,
KIT,
PDGFRB,
RAF1,
RET 💬
89件: Acute myeloid leukemia, Alcoholism, Alzheimer disease, Apelin signaling pathway, Apoptosis, Autophagy - animal, Axon guidance, B cell receptor signaling pathway, Bladder cancer, Breast cancer, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Serotonergic synapse, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Tuberculosis, VEGF signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway, mTOR signaling pathway 💬2件: 34, 86
94 Sorbitol 3件: D-glucitol; D-SORBITOL; Sorbitol1件: D00096 --4件: 6, 10, 28, 299
95 Sotatercept 1件: SOTATERCEPT1件: D09670 1件: ACVR2A 💬4件: Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway 💬2件: 86, 284
96 Sotrastaurin 1件: Sotrastaurin1件: D09671 4件: PRKCD,
PRKCE,
PRKCH,
PRKCQ 💬
29件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Aldosterone synthesis and secretion, Apelin signaling pathway, Autophagy - animal, C-type lectin receptor signaling pathway, Chemical carcinogenesis - reactive oxygen species, Chemokine signaling pathway, Diabetic cardiomyopathy, Estrogen signaling pathway, Fc gamma R-mediated phagocytosis, GnRH signaling pathway, Inflammatory mediator regulation of TRP channels, Insulin resistance, MicroRNAs in cancer, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Prion disease, Shigellosis, Sphingolipid signaling pathway, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 97
97 Soybean 1件: Soybean---1件: 97
98 Sparsentan 1件: SPARSENTAN1件: D11776 2件: AGTR1,
EDNRA 💬
17件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 66, 218, 222
99 Spectinomycin 0件: 2件: D00869 ,
D08526
--1件: 13
100 Spesolimab 1件: SPESOLIMAB1件: D12066 1件: IL1RL2 💬1件: Cytokine-cytokine receptor interaction 💬3件: 37, 96, 97
101 Spironolactone 1件: Spironolactone1件: D00443 1件: NR3C2 💬1件: Aldosterone-regulated sodium reabsorption 💬7件: 58, 67, 86, 113, 210, 218, 225
102 Spirulina platensis 2件: Spirulina; Spirulina platensis---1件: 299
103 SRT-2104 0件: ---1件: 97
104 Stannsoporfin 1件: Tin mesoporphyrin1件: D05922 2件: HMOX1,
HMOX2 💬
10件: Chemical carcinogenesis - reactive oxygen species, Ferroptosis, Fluid shear stress and atherosclerosis, HIF-1 signaling pathway, Hepatocellular carcinoma, Metabolic pathways, MicroRNAs in cancer, Mineral absorption, Pathways in cancer, Porphyrin metabolism 💬1件: 254
105 Stanozolol 1件: Stanozolol1件: D00444 1件: AR 💬4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬1件: 60
106 Starch, corn 2件: Corn starch; Cornstarch1件: D05297 --3件: 49, 90, 257
107 Stavudine 1件: Stavudine1件: D00445 --1件: 265
108 STG-001 1件: STG-001---1件: 301
109 Stiripentol 2件: DIACOMIT; Stiripentol1件: D05928 --1件: 140
110 Streptococcus pneumoniae type 1 capsular polysaccharide antigen 2件: Pneumovax 23; Prevenar 13---6件: 13, 14, 46, 50, 96, 222
111 Streptococcus pneumoniae type 10a capsular polysaccharide antigen 1件: Pneumovax 23---2件: 46, 50
112 Streptococcus pneumoniae type 11a capsular polysaccharide antigen 1件: Pneumovax 23---2件: 46, 50
113 Streptococcus pneumoniae type 12f capsular polysaccharide antigen 1件: Pneumovax 23---2件: 46, 50
114 Streptococcus pneumoniae type 14 capsular polysaccharide antigen 2件: Pneumovax 23; Prevenar 13---6件: 13, 14, 46, 50, 96, 222
115 Streptococcus pneumoniae type 15b capsular polysaccharide antigen 1件: Pneumovax 23---2件: 46, 50
116 Streptococcus pneumoniae type 17f capsular polysaccharide antigen 1件: Pneumovax 23---2件: 46, 50
117 Streptococcus pneumoniae type 18c capsular polysaccharide antigen 2件: Pneumovax 23; Prevenar 13---6件: 13, 14, 46, 50, 96, 222
118 Streptococcus pneumoniae type 19a capsular polysaccharide antigen 2件: Pneumovax 23; Prevenar 13---6件: 13, 14, 46, 50, 96, 222
119 Streptococcus pneumoniae type 19f capsular polysaccharide antigen 2件: Pneumovax 23; Prevenar 13---6件: 13, 14, 46, 50, 96, 222
120 Streptococcus pneumoniae type 2 capsular polysaccharide antigen 1件: Pneumovax 23---2件: 46, 50
121 Streptococcus pneumoniae type 20 capsular polysaccharide antigen 1件: Pneumovax 23---2件: 46, 50
122 Streptococcus pneumoniae type 22f capsular polysaccharide antigen 1件: Pneumovax 23---2件: 46, 50
123 Streptococcus pneumoniae type 23f capsular polysaccharide antigen 2件: Pneumovax 23; Prevenar 13---6件: 13, 14, 46, 50, 96, 222
124 Streptococcus pneumoniae type 3 capsular polysaccharide antigen 2件: Pneumovax 23; Prevenar 13---6件: 13, 14, 46, 50, 96, 222
125 Streptococcus pneumoniae type 33f capsular polysaccharide antigen 1件: Pneumovax 23---2件: 46, 50
126 Streptococcus pneumoniae type 4 capsular polysaccharide antigen 2件: Pneumovax 23; Prevenar 13---6件: 13, 14, 46, 50, 96, 222
127 Streptococcus pneumoniae type 5 capsular polysaccharide antigen 2件: Pneumovax 23; Prevenar 13---6件: 13, 14, 46, 50, 96, 222
128 Streptococcus pneumoniae type 6b capsular polysaccharide antigen 2件: Pneumovax 23; Prevenar 13---6件: 13, 14, 46, 50, 96, 222
129 Streptococcus pneumoniae type 7f capsular polysaccharide antigen 2件: Pneumovax 23; Prevenar 13---6件: 13, 14, 46, 50, 96, 222
130 Streptococcus pneumoniae type 8 capsular polysaccharide antigen 1件: Pneumovax 23---2件: 46, 50
131 Streptococcus pneumoniae type 9n capsular polysaccharide antigen 1件: Pneumovax 23---2件: 46, 50
132 Streptococcus pneumoniae type 9v capsular polysaccharide antigen 2件: Pneumovax 23; Prevenar 13---6件: 13, 14, 46, 50, 96, 222
133 Strontium ranelate 1件: Strontium ranelate1件: D08468 --1件: 78
134 Succimer 1件: DMSA1件: D00572 --1件: 171
135 Sucralfate 1件: Sucralfate1件: D00446 --1件: 98
136 Sucrose 1件: Sucrose1件: D00025 --3件: 62, 96, 97
137 Sufentanil 1件: Sufentanil2件: D00845 ,
D05938
1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬2件: 70, 280
138 Sulfachlorpyridazine 0件: 1件: D05948 --1件: 6
139 Sulfadoxine 1件: Sulfadoxine1件: D00580 --1件: 65
140 Sulfamethoxazole 3件: Bactrim; Sulfamethoxazole; Sulphamethoxazole1件: D00447 --5件: 44, 49, 61, 85, 299
141 Sulfanilamide 0件: 1件: D08543 --5件: 6, 30, 60, 118, 298
142 Sulfasalazine 3件: Salazosulfapyridine; Salicylazosulfapyridine; Sulfasalazine1件: D00448 --6件: 46, 86, 94, 107, 270, 271
143 Sulfate ion 1件: Sulfate---27件: 2, 3, 6, 11, 13, 26, 28, 34, 36, 46, 49, 53, 60, 64, 66, 79, 85, 86, 96, 111, 218, 222, 226, 265, 296, 297, 299
144 Sulforaphane 1件: Sulforaphane---2件: 6, 205
145 Sulfur hexafluoride 3件: SonoVue; Sulfur hexafluoride; Sulphur hexafluoride1件: D05962 --2件: 96, 215
146 Sulindac 1件: Sulindac1件: D00120 2件: PTGS1,
PTGS2 💬
23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 206
147 Sulodexide 0件: 1件: D08547 2件: SERPINC1,
SERPIND1 💬
1件: Complement and coagulation cascades 💬4件: 13, 51, 271, 288
148 Sulpiride 0件: 2件: D01226 ,
D08549
1件: DRD2 💬8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬5件: 2, 6, 17, 46, 70
149 Sumanirole 1件: Sumanirole---1件: 6
150 Sunflower oil 1件: Sunflower oil1件: D09006 --3件: 46, 240, 299
151 Sunitinib 2件: Sunitinib; Sunitinib malate2件: D06402 ,
D08552
9件: CSF1,
FLT1,
FLT3,
FLT4,
KDR,
KIT,
PDGFRA,
PDGFRB,
RET 💬
39件: Acute myeloid leukemia, Alzheimer disease, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Glioma, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, TNF signaling pathway, Thyroid cancer, Transcriptional misregulation in cancer, VEGF signaling pathway, Viral protein interaction with cytokine and cytokine receptor 💬2件: 28, 34
152 Suramin 1件: Suramin---1件: 331
153 Susoctocog alfa 1件: OBIZUR1件: D10831 --1件: 288
154 Sutimlimab 1件: Sutimlimab1件: D11530 1件: C1S 💬5件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Pertussis, Staphylococcus aureus infection, Systemic lupus erythematosus 💬1件: 61
155 Suvorexant 1件: Suvorexant1件: D10082 2件: HCRTR1,
HCRTR2 💬
1件: Neuroactive ligand-receptor interaction 💬3件: 5, 6, 13