Drug Description in Trials / DrugBank / KEGG DRUG


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No. DrugBank 薬物名(臨床試験情報から抽出) KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes
指定難病告示番号
1 Abacavir 4件: Abacavir; Abacavir sulfate; Triumeq; Ziagen2件: D00891 ,
D07057
--4件: 2, 135, 265, 325
2 Abatacept 2件: ABATACEPT; Orencia1件: D03203 2件: CD80,
CD86 💬
12件: Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis 💬26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300
3 Abemaciclib 1件: Abemaciclib1件: D10688 2件: CDK4,
CDK6 💬
29件: AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Breast cancer, Cell cycle, Cellular senescence, Chronic myeloid leukemia, Cushing syndrome, Endocrine resistance, Epstein-Barr virus infection, Glioma, Hepatitis C, Hepatocellular carcinoma, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Measles, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Small cell lung cancer, T cell receptor signaling pathway, Tight junction, Viral carcinogenesis, p53 signaling pathway 💬1件: 34
4 Abetimus 1件: Abetimus---1件: 49
5 ABH001 1件: ABH001---1件: 36
6 Abiraterone 3件: Abiraterone; Abiraterone Acetate; ZYTIGA---2件: 75, 81
7 Abituzumab 1件: Abituzumab---1件: 51
8 Abrilumab 1件: Abrilumab1件: D10540 2件: ITGA4,
ITGB7 💬
15件: Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Human papillomavirus infection, Hypertrophic cardiomyopathy, Intestinal immune network for IgA production, Leishmaniasis, Leukocyte transendothelial migration, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Transcriptional misregulation in cancer, Yersinia infection 💬2件: 96, 97
9 ABX-1431 1件: ABX-1431---1件: 13
10 ABX-464 0件: ---3件: 46, 96, 97
11 AC-430 0件: ---1件: 46
12 Acacia 1件: Gum Arabic1件: D02779 --1件: 46
13 Acalabrutinib 1件: Acalabrutinib1件: D10893 1件: BTK 💬7件: B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬2件: 46, 61
14 Acamprosate 1件: Acamprosate2件: D02780 ,
D07058
5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬
20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬2件: 6, 206
15 Acarbose 1件: Acarbose1件: D00216 5件: AMY2A,
AMY2B,
GAA,
GANC,
MGAM 💬
7件: Carbohydrate digestion and absorption, Galactose metabolism, Lysosome, Metabolic pathways, Pancreatic secretion, Salivary secretion, Starch and sucrose metabolism 💬1件: 298
16 Acebilustat 1件: Acebilustat---1件: 299
17 Aceclofenac 1件: Aceclofenac1件: D01545 3件: PTGES,
PTGS1,
PTGS2 💬
23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 46
18 Aceneuramic acid 1件: ACENEURAMIC ACID1件: D11016 --1件: 30
19 Acetamide 1件: Acetamide---2件: 86, 154
20 Acetaminophen 5件: Acetaminophen; Oxycodone/Acetaminophen; Paracetamol; Tylenol; Ultracet1件: D00217 2件: PTGS1,
PTGS2 💬
23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬18件: 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337
21 Acetate 1件: Acetate---43件: 1, 2, 6, 10, 13, 35, 40, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 162, 171, 206, 222, 224, 225, 227, 235, 265, 288, 298, 299
22 Acetazolamide 1件: Acetazolamide2件: D00218 ,
D01196
13件: CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬
7件: Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬8件: 13, 86, 90, 115, 154, 155, 225, 230
23 Acetic acid 1件: Acetic acid1件: D00010 --1件: 97
24 Acetic acid C-11 1件: 11C-ACETATE---3件: 13, 86, 88
25 Acetohydroxamic acid 1件: Acetohydroxamic Acid1件: D00220 --2件: 6, 251
26 Acetylcarnitine 2件: Acetyl-L-carnitine; Acetylcarnitine---3件: 2, 265, 298
27 Acetylcholine 1件: Acetylcholine---1件: 11
28 Acetylcysteine 3件: Acetylcysteine; Mucomyst; N-acetylcysteine1件: D00221 --20件: 6, 13, 19, 20, 34, 49, 51, 53, 58, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337
29 Acetylsalicylic acid 2件: Acetylsalicylic Acid; Aspirin1件: D00109 2件: PTGS1,
PTGS2 💬
23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬15件: 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251
30 Acipimox 1件: Acipimox1件: D07190 --2件: 78, 265
31 Acitretin 1件: Acitretin1件: D02754 5件: RARA,
RARB,
RXRA,
RXRB,
RXRG 💬
19件: Acute myeloid leukemia, Adipocytokine signaling pathway, Bile secretion, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Gastric cancer, Hepatitis C, Lipid and atherosclerosis, Non-alcoholic fatty liver disease, Non-small cell lung cancer, PI3K-Akt signaling pathway, PPAR signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer 💬1件: 37
32 Acotiamide 1件: Acotiamide---1件: 51
33 ACR-16 0件: ---1件: 8
34 ACR325 1件: ACR325---1件: 6
35 Acteoside 1件: Acteoside---1件: 66
36 Activated charcoal 1件: Carbon---9件: 6, 46, 50, 51, 85, 86, 96, 97, 298
37 Acyclovir 3件: ACICLOVIR; Acycloguanosine; Acyclovir1件: D00222 --5件: 13, 28, 46, 53, 60
38 Adalimumab 6件: Adalimumab; Amgevita; Hulio; Humira; Hyrimoz; Imraldi1件: D02597 1件: TNF 💬67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271
39 Adefovir 1件: Adefovir1件: D02768 --1件: 46
40 Ademetionine 2件: SAM-e; SAMe1件: D07128 --2件: 6, 93
41 Adenine 1件: Adenin1件: D00034 --1件: 46
42 Adenosine 2件: Adenosine; Ginseng1件: D00045 4件: ADORA1,
ADORA2A,
ADORA2B,
ADORA3 💬
12件: Alcoholism, Calcium signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 13, 58, 65
43 Adenosine phosphate 0件: 1件: D02769 4件: ADORA1,
ADORA2A,
ADORA2B,
ADORA3 💬
12件: Alcoholism, Calcium signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 46
44 Adipose-Derived Mesenchymal Stem Cells: Autologous or Allogeneic Origins 1件: HB-adMSCs---7件: 2, 4, 6, 13, 46, 49, 113
45 ADL5859 1件: ADL5859---1件: 46
46 Adrabetadex 1件: Adrabetadex---1件: 19
47 Afamelanotide 2件: Afamelanotide; SCENESSE1件: D10511 1件: MC1R 💬2件: Melanogenesis, Neuroactive ligand-receptor interaction 💬3件: 159, 161, 254
48 Afegostat 1件: Afegostat1件: D09576 --1件: 19
49 Afimetoran 1件: BMS-9862561件: D11908 --1件: 49
50 Aflibercept 2件: Aflibercept; Eylea1件: D09574 3件: PGF,
VEGFA,
VEGFB 💬
24件: AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Calcium signaling pathway, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, EGFR tyrosine kinase inhibitor resistance, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, MAPK signaling pathway, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, VEGF signaling pathway 💬2件: 90, 166
51 Agalsidase alfa 5件: AGALSIDASE ALFA; Agalsidase Alpha; Alpha-galactosidase A; Recombinant alpha-galactosidase A; REPLAGAL1件: D02784 1件: GLA 💬6件: Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome, Metabolic pathways, Sphingolipid metabolism 💬1件: 19
52 Agalsidase beta 2件: AGALSIDASE BETA; FABRAZYME1件: D03228 1件: GLA 💬6件: Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome, Metabolic pathways, Sphingolipid metabolism 💬1件: 19
53 Agomelatine 1件: Agomelatine1件: D02578 3件: HTR2C,
MTNR1A,
MTNR1B 💬
6件: Calcium signaling pathway, Circadian entrainment, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse 💬1件: 6
54 Ajulemic acid 1件: Ajulemic acid1件: D11312 1件: CNR2 💬1件: Neuroactive ligand-receptor interaction 💬3件: 50, 51, 299
55 AK106-001616 1件: AK106-001616---1件: 46
56 AKCEA-TTR-LRx 1件: Eplontersen---1件: 28
57 Alanine 2件: Alanine; L-alanine1件: D00012 --5件: 6, 13, 251, 298, 299
58 Albendazole 2件: Albendazole; Eskazole1件: D00134 --12件: 5, 6, 7, 13, 28, 51, 67, 86, 96, 97, 114, 127
59 Albumin human 5件: Albumin; Human albumin; Human serum albumin; Optison; Serum albumin2件: D02792 ,
D05424
--3件: 2, 78, 96
60 Aldesleukin 4件: ALDESLEUKIN; ILT-101; Proleukin; Recombinant human interleukin-21件: D00748 3件: IL2RA,
IL2RB,
IL2RG 💬
14件: Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Inflammatory bowel disease, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Primary immunodeficiency, Th1 and Th2 cell differentiation, Th17 cell differentiation, Transcriptional misregulation in cancer, Viral protein interaction with cytokine and cytokine receptor 💬6件: 2, 35, 49, 65, 96, 97
61 Aldosterone 1件: Aldosterone1件: D10528 1件: NR3C2 💬1件: Aldosterone-regulated sodium reabsorption 💬1件: 222
62 Alefacept 1件: Alefacept1件: D02800 1件: CD58 💬2件: Cell adhesion molecules, Epstein-Barr virus infection 💬6件: 37, 60, 65, 164, 284, 285
63 Alemtuzumab 4件: Alemtuzumab; Campath; Lemtrada; MABCAMPATH1件: D02802 --22件: 13, 15, 19, 20, 36, 43, 44, 46, 49, 51, 60, 62, 63, 65, 85, 96, 164, 234, 283, 284, 285, 326
64 Alendronic acid 3件: Alendronate; Alendronate sodium; Alendronic acid2件: D00939 ,
D07119
1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬7件: 19, 41, 46, 50, 271, 274, 299
65 Alfacalcidol 2件: Alfacalcidol; One-alpha1件: D01518 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬8件: 41, 46, 49, 50, 96, 107, 235, 238
66 Alfuzosin 1件: Alfuzosin2件: D01692 ,
D07124
1件: ADRA1A 💬7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 13
67 Alginic acid 3件: Algin; Alginate; Alginic acid1件: D02324 --4件: 51, 53, 97, 299
68 Alglucerase 1件: Ceredase1件: D02810 1件: GBA 💬4件: Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism 💬1件: 19
69 Alglucosidase alfa 4件: ALGLUCOSIDASE ALFA; Alpha-glucosidase; Lumizyme; Myozyme1件: D03207 1件: GAA 💬4件: Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism 💬1件: 256
70 Alicaforsen 1件: Alicaforsen---2件: 96, 97
71 Alirocumab 2件: ALIROCUMAB; Praluent1件: D10335 1件: PCSK9 💬1件: Cholesterol metabolism 💬1件: 79
72 Aliskiren 1件: Aliskiren1件: D03208 1件: REN 💬3件: Diabetic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬3件: 66, 167, 222
73 Alitretinoin 2件: ALITRETINOIN; Toctino1件: D02815 5件: RARA,
RARB,
RXRA,
RXRB,
RXRG 💬
19件: Acute myeloid leukemia, Adipocytokine signaling pathway, Bile secretion, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Gastric cancer, Hepatitis C, Lipid and atherosclerosis, Non-alcoholic fatty liver disease, Non-small cell lung cancer, PI3K-Akt signaling pathway, PPAR signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer 💬1件: 49
74 Alkaline Phosphatase 1件: Alkaline Phosphatase---4件: 46, 93, 97, 172
75 Allantoin 1件: ALLANTOIN1件: D00121 --1件: 36
76 Allogenic Donor CD362-enriched Human Umbilical Cord-derived Mesenchymal Stem Cells 1件: Orbcel-C---2件: 94, 95
77 Allopurinol 2件: Allopurinol; ALLOPURINOL SODIUM1件: D00224 1件: XDH 💬5件: Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Peroxisome, Purine metabolism 💬6件: 6, 46, 57, 66, 96, 97
78 Aloe vera leaf 3件: Aloe; Aloe vera; Aloe vera gel---3件: 53, 97, 226
79 Alpha-1-proteinase inhibitor 6件: Alpha 1-Antitrypsin; Alpha 1-Proteinase Inhibitor; ALPHA-1-ANTITRYPSIN; Alpha1-proteinase Inhibitor; Glassia; Prolastin-C---3件: 231, 298, 299
80 alpha-Linolenic acid 1件: Linolenic acid---2件: 46, 286
81 alpha-Tocopherol acetate 3件: Tocopherol acetate; TOCOPHERYL ACETATE; Vitamin E---2件: 49, 206
82 Alprazolam 1件: Alprazolam1件: D00225 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬
7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬2件: 8, 75
83 Alprostadil 1件: Alprostadil2件: D00180 ,
D02705
1件: PTGER1 💬4件: Calcium signaling pathway, Human cytomegalovirus infection, Neuroactive ligand-receptor interaction, Pathways in cancer 💬2件: 51, 70
84 Altropane 1件: Altropane---1件: 6
85 ALTU-135 1件: ALTU-135---1件: 299
86 Aluminium 2件: Aluminium; Aluminum---2件: 11, 46
87 Aluminium phosphate 1件: Aluminium phosphate---1件: 46
88 Aluminum hydroxide 2件: Aluminium hydroxide; Aluminum hydroxide1件: D02416 --2件: 11, 46
89 Alunacedase alfa 1件: Recombinant Human Angiotensin-Converting Enzyme 2---1件: 86
90 Alvelestat 1件: ALVELESTAT---1件: 231
91 Amantadine 3件: Amantadine; AMANTADINE HYDROCHLORIDE; GOCOVRI2件: D00777 ,
D07441
5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬
20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬4件: 6, 8, 13, 127
92 Ambrisentan 3件: AMBRISENTAN; Letairis; Volibris1件: D07077 1件: EDNRA 💬7件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬7件: 51, 84, 85, 86, 88, 210, 211
93 Ambroxol 1件: Ambroxol1件: D07442 --2件: 6, 19
94 AMG 108 1件: AMG 108---1件: 46
95 Amifampridine 2件: Amifampridine; Firdapse1件: D10228 4件: KCNA4,
KCNC3,
KCND2,
KCND3 💬
4件: Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬3件: 3, 11, 12
96 Amifostine 1件: Amifostine1件: D00226 --1件: 28
97 Amikacin 5件: Amikacin; AMIKACIN SULFATE; Amikacina; Amikacine; Arikayce2件: D00865 ,
D02543
--2件: 60, 299
98 Amiloride 3件: AMILORIDE; Amiloride Hydrochloride; Midamor2件: D00649 ,
D07447
3件: SCNN1A,
SCNN1B,
SCNN1G 💬
2件: Aldosterone-regulated sodium reabsorption, Taste transduction 💬4件: 13, 67, 225, 299
99 Amino acids 1件: Amino acids---3件: 70, 240, 298
100 Aminocaproic acid 2件: Aminocaproic acid; EACA1件: D00160 1件: PLG 💬4件: Complement and coagulation cascades, Influenza A, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection 💬1件: 70
101 Aminohippuric acid 1件: Aminohippurate2件: D01421 ,
D06890
--4件: 49, 53, 67, 86
102 Aminolevulinic acid 3件: 5-aminolevulinic acid; Aminolevulinic acid; Gliolan2件: D02908 ,
D07567
--5件: 34, 96, 97, 254, 286
103 Aminophylline 1件: Aminophylline2件: D00227 ,
D05429
18件: ADORA1,
ADORA2B,
PDE10A,
PDE11A,
PDE1A,
PDE1B,
PDE1C,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE7A,
PDE7B,
PDE8A,
PDE8B 💬
23件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 63
104 Aminopterin 1件: Aminopterin---1件: 46
105 Aminosalicylic acid 2件: 4-Aminosalicylic acid; AMINOSALICYLIC ACID1件: D00162 --3件: 13, 96, 97
106 Amiodarone 1件: AMIODARONE2件: D00636 ,
D02910
16件: ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
KCND3,
KCNJ11,
KCNJ12,
KCNJ3,
KCNJ5,
KCNJ8,
KCNQ1,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬
32件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Dilated cardiomyopathy, Dopaminergic synapse, Estrogen signaling pathway, Gap junction, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, Insulin secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, Pancreatic secretion, Protein digestion and absorption, Regulation of lipolysis in adipocytes, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Type II diabetes mellitus, Vascular smooth muscle contraction, Vibrio cholerae infection, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 28, 127
107 Amitriptyline 3件: Amitriptylin; AMITRIPTYLINE; Amitriptyline hydrochloride2件: D00809 ,
D07448
2件: SLC6A2,
SLC6A4 💬
2件: Serotonergic synapse, Synaptic vesicle cycle 💬4件: 78, 97, 226, 299
108 Amlodipine 1件: AMLODIPINE3件: D00615 ,
D02914 ,
D07450
4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬
37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 13, 51, 67, 298
109 Ammonia 1件: Ammonia1件: D02916 --3件: 86, 88, 296
110 Ammonium chloride 1件: Ammonium chloride1件: D01139 --3件: 96, 107, 251
111 Amniotic Epithelial Cells 1件: Amniotic Epithelial Cells---1件: 26
112 Amoxapine 1件: Amoxapine1件: D00228 2件: SLC6A2,
SLC6A4 💬
2件: Serotonergic synapse, Synaptic vesicle cycle 💬1件: 46
113 Amoxicillin 4件: Amoxicilina; Amoxicillin; Amoxycillin; Augmentin3件: D00229 ,
D02925 ,
D07452
--9件: 6, 19, 46, 63, 84, 96, 97, 222, 299
114 Amphotericin B 2件: ABELCET; Amphotericin B1件: D00203 --1件: 299
115 Ampicillin 1件: ABPC3件: D00204 ,
D01251 ,
D02119
--5件: 2, 6, 13, 84, 299
116 Ampreloxetine 1件: Ampreloxetine1件: D11688 2件: SLC6A2,
SLC6A4 💬
2件: Serotonergic synapse, Synaptic vesicle cycle 💬2件: 6, 17
117 Amprenavir 1件: Amprenavir1件: D00894 --1件: 265
118 Amyl Nitrite 1件: Amyl Nitrite1件: D00517 3件: GUCY1A1,
GUCY1A2,
GUCY1B1 💬
11件: Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 58
119 Anacetrapib 1件: ANACETRAPIB1件: D08855 1件: CETP 💬1件: Cholesterol metabolism 💬1件: 79
120 Anakinra 2件: Anakinra; Kineret1件: D02934 2件: IL1R1,
IL1R2 💬
15件: Amoebiasis, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Pathogenic Escherichia coli infection, Prostate cancer, Shigellosis, Th17 cell differentiation, Transcriptional misregulation in cancer 💬19件: 2, 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299
121 Anastrozole 2件: Anastrozole; Arimidex1件: D00960 1件: CYP19A1 💬3件: Metabolic pathways, Ovarian steroidogenesis, Steroid hormone biosynthesis 💬3件: 78, 86, 193
122 Andrographolide 1件: Andrographolide---1件: 97
123 Anfibatide 1件: Anfibatide---1件: 64
124 Angiotensin II 2件: Angiotensin; Angiotensin II2件: D00150 ,
D02014
2件: AGTR1,
AGTR2 💬
16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬7件: 17, 19, 46, 66, 86, 222, 224
125 Anifrolumab 1件: ANIFROLUMAB1件: D11082 2件: IFNAR1,
IFNAR2 💬
18件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬2件: 46, 49
126 anle138b 1件: Anle138b---1件: 6
127 Anrukinzumab 1件: Anrukinzumab1件: D08857 1件: IL13 💬8件: Asthma, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, IL-17 signaling pathway, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation 💬1件: 97
128 Antihemophilic factor human 6件: Alphanate; Factor VIII; HUMAN COAGULATION FACTOR VIII; Humate-P; Voncento; WILATE---1件: 288
129 Antihemophilic factor, human recombinant 4件: ADVATE; Factor VIII; OCTOCOG ALFA; RAHF1件: D02958 --1件: 288
130 Antilymphocyte immunoglobulin (horse) 4件: Anti-Thymocyte Globulin; Atgam; HATG; Horse anti-thymocyte globulin---1件: 60
131 Antithymocyte immunoglobulin (rabbit) 10件: Anti-thymocyte globulin; ANTITHYMOCYTE IMMUNOGLOBULIN; Antithymocyte immunoglobulin (rabbit); Lapine T-Lymphocyte Immune Globulin; Rabbit anti-human thymocyte immunoglobulin; Rabbit antithymocyte globulin; Rabbit ATG; RATG; Thymoglobulin; THYMOGLOBULINE---12件: 13, 36, 49, 51, 60, 62, 65, 96, 283, 285, 286, 326
132 ANX-510 0件: ---3件: 6, 265, 288
133 Apabetalone 1件: Apabetalone1件: D11131 --1件: 86
134 Apadamtase alfa 1件: Apadamtase alfa---1件: 64
135 Apigenin 1件: Apigenin---1件: 97
136 Apitegromab 1件: Apitegromab1件: D11797 1件: MSTN 💬1件: Cytokine-cytokine receptor interaction 💬1件: 3
137 Apixaban 2件: Apixaban; Eliquis1件: D03213 1件: F10 💬1件: Complement and coagulation cascades 💬3件: 96, 97, 222
138 Aplindore 1件: Aplindore---1件: 6
139 Apomorphine 3件: APOKYN; Apomorfina; Apomorphine2件: D02004 ,
D07460
2件: DRD1,
DRD2 💬
11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 5, 6, 7
140 Apple 1件: Apple---1件: 70
141 Apraclonidine 1件: Apraclonidine2件: D01008 ,
D07461
3件: ADRA2A,
ADRA2B,
ADRA2C 💬
2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬1件: 11
142 Apratastat 1件: Apratastat1件: D08859 2件: ADAM17,
MMP13 💬
7件: Alzheimer disease, Coronavirus disease - COVID-19, Epithelial cell signaling in Helicobacter pylori infection, IL-17 signaling pathway, Notch signaling pathway, Parathyroid hormone synthesis, secretion and action, Relaxin signaling pathway 💬1件: 46
143 Apremilast 2件: Apremilast; Otezla1件: D08860 4件: PDE4A,
PDE4B,
PDE4C,
PDE4D 💬
5件: Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬7件: 46, 50, 56, 97, 107, 162, 271
144 Aprotinin 1件: Aprotinin1件: D02971 --1件: 28
145 AQX-1125 1件: AQX-1125---1件: 226
146 AR-42 1件: AR-42---1件: 34
147 Arabica coffee bean 1件: Coffee---2件: 96, 97
148 Aramchol 1件: Aramchol---1件: 265
149 Arbaclofen 2件: Arbaclofen; Baclofen1件: D09791 2件: GABBR1,
GABBR2 💬
7件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬2件: 13, 206
150 Arbaclofen Placarbil 1件: Arbaclofen Placarbil1件: D08861 2件: GABBR1,
GABBR2 💬
7件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬1件: 13
151 Arginine 6件: Arginina; Arginine; L-Arg; L-Arginin; L-arginine; R-Gene1件: D02982 --12件: 46, 58, 65, 67, 78, 96, 97, 98, 113, 210, 251, 299
152 Arimoclomol 1件: ARIMOCLOMOL1件: D11374 --3件: 2, 15, 19
153 Aripiprazole 1件: Aripiprazole1件: D01164 4件: DRD2,
DRD3,
HTR1A,
HTR2A 💬
12件: Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬2件: 6, 206
154 Armodafinil 2件: Armodafinil; Modafinil1件: D03215 1件: SLC6A3 💬7件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬3件: 6, 13, 84
155 Artenimol 1件: Dihydroartemisinin1件: D07362 --1件: 49
156 Artesunate 1件: Artesunate1件: D02482 --8件: 18, 46, 53, 66, 96, 97, 215, 271
157 Arundic acid 1件: Arundic Acid1件: D06296 --1件: 2
158 ARX201 1件: ARX201---1件: 78
159 Ascorbic acid 4件: Acidum ascorbicum; Ascorbic acid; Iron; Vitamin C1件: D00018 --8件: 10, 97, 192, 206, 210, 211, 212, 298
160 Asfotase alfa 2件: ASFOTASE ALFA; Strensiq1件: D10595 1件: ALPL 💬4件: Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, Thiamine metabolism 💬1件: 172
161 Asparaginase Escherichia coli 2件: Asparaginase; L-asparaginase1件: D02997 --1件: 65
162 Aspartame 0件: 1件: D02381 2件: TAS1R2,
TAS1R3 💬
2件: Carbohydrate digestion and absorption, Taste transduction 💬5件: 6, 13, 67, 86, 230
163 Aspergillus oryzae 1件: Aspergillus oryzae---1件: 97
164 AstraZeneca COVID-19 Vaccine 3件: ChAdOx1 nCoV-19; Covid-19 Vaccine Astrazeneca; Vaxzevria---4件: 46, 51, 53, 299
165 AT2220 1件: AT2220---1件: 256
166 Atacicept 2件: ATACICEPT; TACI-Fc51件: D09704 2件: TNFSF13,
TNFSF13B 💬
4件: Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬4件: 13, 46, 49, 66
167 Ataluren 2件: Ataluren; Translarna1件: D09323 --6件: 19, 113, 140, 246, 299, 329
168 Atazanavir 2件: Atazanavir; Reyataz2件: D01276 ,
D07471
--1件: 265
169 Atenolol 1件: ATENOLOL1件: D00235 1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 167
170 Atezolizumab 1件: Atezolizumab1件: D10773 1件: CD274 💬2件: Cell adhesion molecules, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬1件: 85
171 ATL-2502 1件: ATL-2502---1件: 97
172 ATL1102 1件: ATL1102---1件: 13
173 Atomoxetine 2件: Atomoxetine; Strattera2件: D02574 ,
D07473
1件: SLC6A2 💬1件: Synaptic vesicle cycle 💬4件: 6, 8, 13, 17
174 Atorvastatin 3件: Atorvastatin; Atorvastatin Calcium; Lipitor3件: D00258 ,
D00887 ,
D07474
1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬18件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299
175 Atosiban 1件: Atosiban1件: D03008 1件: OXTR 💬4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬1件: 118
176 Atovaquone 1件: ATOVAQUONE1件: D00236 --1件: 61
177 Atrasentan 1件: ATRASENTAN---3件: 66, 218, 222
178 Atropine 2件: Atropina; Atropine5件: D00113 ,
D01077 ,
D02069 ,
D03011 ,
D03814
5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬
13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬2件: 2, 299
179 ATYR1923 1件: ATYR1923---1件: 84
180 AV-101 1件: AV-101---2件: 6, 86
181 Avacincaptad pegol 1件: Avacincaptad pegol---1件: 301
182 Avacopan 1件: Avacopan1件: D11093 1件: C5AR1 💬6件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Staphylococcus aureus infection 💬3件: 43, 44, 222
183 Avalglucosidase alfa 2件: Avalglucosidase Alfa; NeoGAA1件: D11744 1件: GAA 💬4件: Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism 💬1件: 256
184 Avatrombopag 2件: Avatrombopag; Doptelet1件: D10306 1件: MPL 💬2件: Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬2件: 60, 63
185 Avdoralimab 1件: Avdoralimab---1件: 162
186 Avibactam 1件: Avibactam---1件: 299
187 Aviptadil 1件: AVIPTADIL1件: D12127 --5件: 49, 51, 84, 85, 86
188 Axitinib 1件: Axitinib1件: D03218 3件: FLT1,
FLT4,
KDR 💬
15件: Breast cancer, Calcium signaling pathway, EGFR tyrosine kinase inhibitor resistance, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, MAPK signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Rheumatoid arthritis, Transcriptional misregulation in cancer, VEGF signaling pathway 💬1件: 34
189 Azathioprine 3件: Azathioprine; Azatioprina; Imuran2件: D00238 ,
D03033
--21件: 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162
190 AZD-0328 0件: ---1件: 6
191 AZD-1236 0件: ---1件: 299
192 AZD-4017 0件: ---1件: 75
193 AZD-5672 0件: ---1件: 46
194 AZD-7325 0件: ---1件: 206
195 AZD-9056 0件: ---2件: 46, 96
196 Azithromycin 5件: Azithromycin; AZITHROMYCIN DIHYDRATE; Azithromycin monohydrate; AZITHROMYCINE; Zithromax3件: D02134 ,
D06390 ,
D07486
--6件: 13, 84, 85, 96, 228, 299
197 Aztreonam 2件: Aztreonam; Cayston2件: D00240 ,
D06558
--2件: 228, 299