Drug Description in Trials / DrugBank / KEGG DRUG


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No. DrugBank 薬物名(臨床試験情報から抽出) KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes
指定難病告示番号
1 Factor IX Complex (Human) 1件: Prothrombin Complex Concentrate---1件: 288
2 Factor XIII (human) 1件: Factor XIII---3件: 51, 97, 288
3 Famciclovir 1件: Famciclovir1件: D00317 --1件: 13
4 Famotidine 2件: FAMOTIDINA; Famotidine1件: D00318 1件: HRH2 💬3件: Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬7件: 6, 46, 61, 86, 98, 107, 300
5 Fasudil 1件: Fasudil1件: D07941 2件: ROCK1,
ROCK2 💬
23件: Axon guidance, Chemokine signaling pathway, Focal adhesion, Human cytomegalovirus infection, Leukocyte transendothelial migration, Lipid and atherosclerosis, MicroRNAs in cancer, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Proteoglycans in cancer, Regulation of actin cytoskeleton, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, TGF-beta signaling pathway, Tight junction, Vascular smooth muscle contraction, Wnt signaling pathway, Yersinia infection, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 2, 5, 7, 51
6 Febuxostat 1件: Febuxostat1件: D01206 1件: XDH 💬5件: Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Peroxisome, Purine metabolism 💬3件: 2, 6, 13
7 Felzartamab 1件: Felzartamab---1件: 66
8 Fenamole 0件: 1件: D04139 --3件: 6, 13, 160
9 Fenebrutinib 1件: FENEBRUTINIB1件: D11457 1件: BTK 💬7件: B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬1件: 13
10 Fenfluramine 2件: Fenfluramina; FENFLURAMINE1件: D07945 4件: HTR2A,
HTR2B,
HTR2C,
SLC6A4 💬
6件: Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬4件: 140, 144, 145, 149
11 Fenofibrate 1件: Fenofibrate1件: D00565 1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬5件: 8, 79, 93, 94, 265
12 Fenretinide 1件: Fenretinide1件: D04162 2件: RARA,
RARB 💬
8件: Acute myeloid leukemia, Estrogen signaling pathway, Gastric cancer, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer 💬1件: 299
13 Fentanyl 1件: Fentanyl2件: D00320 ,
D01399
1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬4件: 46, 70, 215, 231
14 Ferric carboxymaltose 1件: Ferric carboxymaltose1件: D08920 --4件: 86, 96, 97, 299
15 Ferric maltol 1件: Ferric Maltol1件: D10833 --1件: 96
16 Ferric oxide 1件: Iron oxide1件: D04168 --1件: 13
17 Ferric pyrophosphate citrate 0件: 1件: D10933 --1件: 13
18 Ferric sulfate 1件: Stasis1件: D08922 --2件: 66, 97
19 Ferrous sulfate anhydrous 0件: ---1件: 46
20 Ferulic acid 1件: Ferulic acid---1件: 127
21 Ferumoxytol 2件: Feraheme; Ferumoxytol1件: D04177 --1件: 13
22 Fesoterodine 1件: Fesoterodine1件: D07226 2件: CHRM2,
CHRM3 💬
13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬1件: 6
23 Fexinidazole 1件: Fexinidazole1件: D11252 --1件: 65
24 Fexofenadine 1件: Fexofenadine2件: D00671 ,
D07958
1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬2件: 13, 46
25 Fibrin 1件: Fibrin---1件: 96
26 Fibrinogen human 3件: Fibrinogen; Fibrinogen concentrate; HUMAN FIBRINOGEN---3件: 14, 65, 288
27 Fig 1件: Fig---1件: 2
28 Filgotinib 2件: FILGOTINIB; Jyseleca1件: D10871 1件: JAK1 💬27件: Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬6件: 46, 53, 96, 97, 222, 271
29 Filgrastim 7件: Filgrastim; Filgrastim Hexal; G-CSF; Granulocyte Colony Stimulating Factor; Neupogen; TEVAGRASTIM; Zarzio1件: D03235 1件: CSF3R 💬5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬34件: 2, 6, 11, 13, 16, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331
30 Finasteride 1件: Finasteride1件: D00321 1件: SRD5A2 💬3件: Metabolic pathways, Prostate cancer, Steroid hormone biosynthesis 💬1件: 6
31 Fingolimod 2件: Fingolimod; Gilenya1件: D10001 1件: S1PR1 💬3件: FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬3件: 13, 14, 156
32 Fipamezole 1件: Fipamezole---2件: 6, 17
33 Firategrast 1件: Firategrast1件: D06590 1件: ITGA4 💬14件: Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Human papillomavirus infection, Hypertrophic cardiomyopathy, Intestinal immune network for IgA production, Leishmaniasis, Leukocyte transendothelial migration, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Yersinia infection 💬1件: 13
34 Fish oil 4件: Fish oil; Omegaven; Smofkabiven; SMOFLipid---7件: 13, 46, 49, 66, 96, 260, 299
35 Flavoxate 1件: Flavoxate2件: D00718 ,
D07961
16件: PDE10A,
PDE11A,
PDE1A,
PDE1B,
PDE1C,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE7A,
PDE7B,
PDE8A,
PDE8B 💬
18件: Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, Taste transduction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 226
36 Flax seed 1件: Flaxseed---2件: 97, 299
37 Flecainide 3件: Flecainide; FLECAINIDE ACETATE; Flecainidum2件: D00638 ,
D07962
5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬
3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬1件: 6
38 Fletikumab 1件: Anti-IL-201件: D11756 1件: IL20 💬3件: Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Viral protein interaction with cytokine and cytokine receptor 💬1件: 46
39 Florasulam 1件: PRIMUS---1件: 46
40 Florbenazine F-18 1件: 18F-AV-133---1件: 6
41 Florbetaben (18F) 2件: FLORBETABEN (18F); Neuraceq---1件: 6
42 Florbetapir (18F) 2件: Amyvid; Florbetapir (18F)---2件: 13, 127
43 Florilglutamic acid F-18 1件: 18F-FSPG---1件: 84
44 Flortaucipir 1件: Flortaucipir1件: D11210 1件: MAPT 💬4件: Alzheimer disease, MAPK signaling pathway, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬3件: 5, 7, 127
45 Flucloxacillin 1件: FLUCLOXACILLIN3件: D01249 ,
D04196 ,
D07965
--1件: 299
46 Fluconazole 2件: Diflucan; FLUCONAZOLE2件: D00322 ,
D01429
--2件: 96, 225
47 Fludarabine 4件: FLUDARA; FLUDARABINA; Fludarabine; Fludarabine phosphate2件: D01907 ,
D07966
1件: RRM1 💬5件: Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism 💬19件: 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326
48 Fludeoxyglucose 1件: FLUDEOXYGLUCOSE1件: D01843 --4件: 34, 84, 85, 88
49 Fludeoxyglucose (18F) 3件: 18F-FDG; Fludeoxyglucose; Fludeoxyglucose F 18---14件: 5, 6, 7, 8, 13, 34, 41, 46, 53, 84, 85, 96, 127, 300
50 Fludrocortisone 1件: Fludrocortisone2件: D00986 ,
D07967
1件: NR3C2 💬1件: Aldosterone-regulated sodium reabsorption 💬3件: 6, 17, 81
51 Flumazenil 1件: Flumazenil1件: D00697 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬
7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬5件: 6, 13, 17, 18, 206
52 Flunarizine 0件: 2件: D01303 ,
D07971
3件: CACNA1G,
CACNA1H,
CACNA1I 💬
8件: Aldosterone synthesis and secretion, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GnRH secretion, MAPK signaling pathway, Type II diabetes mellitus 💬4件: 58, 86, 149, 215
53 Fluocinolone 1件: Fluocinolone---1件: 90
54 Fluocinolone acetonide 2件: Fluocinolone Acetonide; Iluvien1件: D01825 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 90
55 Fluorescein 1件: Fluorescein2件: D01261 ,
D02024
--3件: 19, 22, 97
56 Fluorine F-18 1件: FLUORINE-181件: D05860 --1件: 41
57 Fluoxetine 5件: Fluoxetin; FLUOXETINE; FLUOXETINE HYDROCHLORIDE; Fluoxétine; PROZAC2件: D00326 ,
D00823
1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬6件: 13, 17, 78, 86, 179, 206
58 Flupentixol 1件: Flupentixol1件: D01044 2件: DRD1,
DRD2 💬
11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 97
59 Flupirtine 1件: Flupirtine1件: D07978 --1件: 13
60 Flurbiprofen 1件: Flurbiprofen3件: D00330 ,
D01475 ,
D02290
2件: PTGS1,
PTGS2 💬
23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬3件: 13, 21, 46
61 Flutamide 1件: Flutamide1件: D00586 1件: AR 💬4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬1件: 81
62 Flutemetamol 1件: Flutemetamol---5件: 5, 6, 7, 17, 127
63 Flutemetamol (18F) 3件: Flutemetamol; Flutemetamol F18; Vizamyl---5件: 5, 6, 7, 17, 127
64 Fluticasone 1件: Fluticasone1件: D07981 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬3件: 98, 228, 299
65 Fluticasone propionate 3件: Flovent; Fluticasone; Fluticasone propionate1件: D01708 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 98, 228
66 Flutriciclamide F-18 1件: 18F-GE-180---1件: 46
67 Fluvastatin 1件: Fluvastatin2件: D00892 ,
D07983
1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬3件: 79, 218, 222
68 Folic acid 5件: Acide folique; Folate; Folic acid; Multivitamin; Nicotinamide1件: D00070 --6件: 6, 13, 41, 46, 49, 84
69 Foliglurax 1件: Foliglurax---1件: 6
70 Fomepizole 1件: 4-Methylpyrazole1件: D00707 3件: ADH1A,
ADH1B,
ADH1C 💬
9件: Alcoholic liver disease, Drug metabolism - cytochrome P450, Fatty acid degradation, Glycolysis / Gluconeogenesis, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Pyruvate metabolism, Retinol metabolism, Tyrosine metabolism 💬1件: 301
71 Fontolizumab 1件: Fontolizumab1件: D04242 1件: IFNG 💬32件: African trypanosomiasis, Allograft rejection, Amoebiasis, Antigen processing and presentation, Chagas disease, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Graft-versus-host disease, HIF-1 signaling pathway, Hepatitis C, Herpes simplex virus 1 infection, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Leishmaniasis, Malaria, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Proteasome, Rheumatoid arthritis, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬1件: 46
72 Foralumab 1件: Foralumab---2件: 13, 96
73 Forigerimod 1件: Forigerimod1件: D09904 --1件: 49
74 Formaldehyde 1件: Formalin1件: D00017 --1件: 84
75 Formoterol 2件: Formoterol; Symbicort3件: D01373 ,
D05277 ,
D07990
1件: ADRB2 💬9件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 85, 228, 299
76 Foscarbidopa 1件: Foscarbidopa1件: D12057 --1件: 6
77 Foscarnet 2件: Foscarnet; Foscarnet sodium2件: D00579 ,
D02267
--2件: 28, 60
78 Fosfomycin 1件: Fosfomycin4件: D00925 ,
D02187 ,
D02188 ,
D04253
--4件: 63, 96, 97, 222
79 Foslevodopa 1件: Foslevodopa1件: D11839 5件: DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬
11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6
80 Fospropofol 1件: Fospropofol---1件: 226
81 Fostamatinib 1件: Fostamatinib1件: D09347 1件: SYK 💬17件: B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Coronavirus disease - COVID-19, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Herpes simplex virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, Osteoclast differentiation, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Platelet activation, Tuberculosis, Viral carcinogenesis 💬4件: 46, 49, 61, 66
82 Fremanezumab 1件: Fremanezumab1件: D11055 1件: CALCA 💬2件: Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction 💬2件: 124, 226
83 Fresolimumab 2件: Fresolimumab; GC10081件: D09620 3件: TGFB1,
TGFB2,
TGFB3 💬
35件: AGE-RAGE signaling pathway in diabetic complications, Amoebiasis, Cell cycle, Cellular senescence, Chagas disease, Chronic myeloid leukemia, Colorectal cancer, Cytokine-cytokine receptor interaction, Diabetic cardiomyopathy, Dilated cardiomyopathy, FoxO signaling pathway, Gastric cancer, Hepatitis B, Hepatocellular carcinoma, Hippo signaling pathway, Human T-cell leukemia virus 1 infection, Hypertrophic cardiomyopathy, Inflammatory bowel disease, Intestinal immune network for IgA production, Leishmaniasis, MAPK signaling pathway, Malaria, MicroRNAs in cancer, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, TGF-beta signaling pathway, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬4件: 51, 85, 222, 274
84 Fucose 2件: Fucose; L-fucose---1件: 65
85 Fulvestrant 2件: Faslodex; Fulvestrant1件: D01161 2件: ESR1,
ESR2 💬
10件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬2件: 49, 86
86 Fumaric acid 1件: Fumaric acid1件: D02308 --2件: 13, 49
87 Furosemide 2件: Furosemide; Furosemide Injection1件: D00331 1件: SLC12A2 💬3件: Pancreatic secretion, Salivary secretion, Vibrio cholerae infection 💬1件: 6
88 Fusidic acid 2件: Fucidin; FUSIDIC ACID1件: D04281 --1件: 299
89 Fx-1006A 1件: Fx-1006A---1件: 28