Drug Description in Trials / DrugBank / KEGG DRUG


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No. DrugBank 薬物名(臨床試験情報から抽出) KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes
指定難病告示番号
1 Pabinafusp alfa 1件: Pabinafusp alfa1件: D11812 2件: IDS,
TFRC 💬
8件: Endocytosis, Ferroptosis, Glycosaminoglycan degradation, HIF-1 signaling pathway, Hematopoietic cell lineage, Lysosome, Metabolic pathways, Phagosome 💬1件: 19
2 Paclitaxel 1件: Paclitaxel2件: D00491 ,
D05333
9件: TUBB,
TUBB1,
TUBB2A,
TUBB2B,
TUBB3,
TUBB4A,
TUBB4B,
TUBB6,
TUBB8 💬
10件: Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection 💬2件: 46, 85
3 Padsevonil 1件: Padsevonil1件: D11842 3件: SV2A,
SV2B,
SV2C 💬
1件: ECM-receptor interaction 💬1件: 149
4 Palifermin 2件: Kepivance; Palifermin1件: D05338 1件: FGFR2 💬13件: Calcium signaling pathway, Central carbon metabolism in cancer, EGFR tyrosine kinase inhibitor resistance, Endocytosis, Gastric cancer, MAPK signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Signaling pathways regulating pluripotency of stem cells 💬5件: 13, 36, 38, 39, 65
5 Palmidrol 1件: Palmitoylethanolamide1件: D08328 --1件: 2
6 Palmitic Acid 1件: Palmitate1件: D05341 --1件: 63
7 Palmitoleic Acid 1件: Palmitoleic Acid---1件: 97
8 Palovarotene 1件: PALOVAROTENE1件: D09365 --1件: 272
9 Pamidronic acid 1件: Pamidronate2件: D00941 ,
D07281
1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬3件: 270, 271, 274
10 Pamrevlumab 1件: PAMREVLUMAB1件: D10969 1件: CCN2 💬2件: Apelin signaling pathway, Hippo signaling pathway 💬2件: 85, 113
11 Panax quinquefolius whole 2件: American Ginseng; Panax Quinquefolius---2件: 13, 46
12 Pancrelipase 2件: Pancreatin; Pancrelipase1件: D05349 --2件: 298, 299
13 Pancrelipase amylase 8件: CREON; PANCREAZE; Pancrelipase; PANCRELIPASE AMYLASE; PERTZYE; Ultrase; ULTRESA; ZENPEP---1件: 299
14 Pantethine 1件: Pantethine1件: D01234 --1件: 120
15 Pantoprazole 1件: Pantoprazole2件: D02593 ,
D05353
2件: ATP4A,
ATP4B 💬
4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬2件: 13, 65
16 Paquinimod 1件: Paquinimod---2件: 49, 51
17 Parathyroid hormone 5件: Natpar; Natpara; Parathyroid hormone; PREOTACT; RhPTH1件: D05364 2件: PTH1R,
PTH2R 💬
3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬4件: 65, 70, 235, 326
18 Pardoprunox 1件: Pardoprunox1件: D09397 3件: DRD2,
DRD3,
HTR1A 💬
10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬1件: 6
19 Parecoxib 1件: Parecoxib1件: D03716 1件: PTGS2 💬22件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬2件: 46, 271
20 Paricalcitol 1件: Paricalcitol1件: D00930 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬4件: 19, 66, 218, 238
21 Parnaparin 2件: Parnaparin; PARNAPARIN SODIUM1件: D07510 1件: SERPINC1 💬1件: Complement and coagulation cascades 💬1件: 97
22 Paroxetine 1件: Paroxetine4件: D02260 ,
D02362 ,
D05374 ,
D05375
1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬4件: 6, 13, 46, 85
23 Parsaclisib 2件: INCB050465; Parsaclisib1件: D11437 1件: PIK3CD 💬106件: AGE-RAGE signaling pathway in diabetic complications, AMPK signaling pathway, Acute myeloid leukemia, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Amoebiasis, Apoptosis, Autophagy - animal, Axon guidance, B cell receptor signaling pathway, Bacterial invasion of epithelial cells, Breast cancer, C-type lectin receptor signaling pathway, Carbohydrate digestion and absorption, Cellular senescence, Central carbon metabolism in cancer, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, Epstein-Barr virus infection, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gastric cancer, Glioma, GnRH secretion, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Inflammatory mediator regulation of TRP channels, Influenza A, Inositol phosphate metabolism, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leukocyte transendothelial migration, Lipid and atherosclerosis, Longevity regulating pathway, Longevity regulating pathway - multiple species, Measles, Melanoma, Metabolic pathways, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Phosphatidylinositol signaling system, Phospholipase D signaling pathway, Platelet activation, Platinum drug resistance, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Small cell lung cancer, Sphingolipid signaling pathway, Spinocerebellar ataxia, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, Type II diabetes mellitus, VEGF signaling pathway, Viral carcinogenesis, Yersinia infection, cAMP signaling pathway, mTOR signaling pathway 💬3件: 35, 53, 61
24 Pasireotide 3件: Pasireotida; PASIREOTIDE; SIGNIFOR1件: D10147 4件: SSTR1,
SSTR2,
SSTR3,
SSTR5 💬
4件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬3件: 67, 74, 75
25 Pateclizumab 1件: MLTA3698A1件: D10187 1件: LTA 💬7件: Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, NF-kappa B signaling pathway, TNF signaling pathway, Type I diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor 💬1件: 46
26 Pazopanib 1件: Pazopanib---1件: 227
27 PCO-371 0件: ---1件: 235
28 PD-0299685 1件: PD-0299685---1件: 226
29 PD-0325901 1件: PD-0325901---1件: 34
30 Peanut 1件: Peanut---1件: 13
31 Pectin 1件: Pectin1件: D02316 --1件: 96
32 Peficitinib 1件: Peficitinib1件: D10653 3件: JAK1,
JAK2,
JAK3 💬
37件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬1件: 46
33 Pegademase 1件: Adagen1件: D05384 --1件: 65
34 Pegcetacoplan 1件: PEGCETACOPLAN1件: D11613 1件: C3 💬17件: Alcoholic liver disease, Chagas disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Phagosome, Shigellosis, Staphylococcus aureus infection, Systemic lupus erythematosus, Tuberculosis, Viral carcinogenesis 💬3件: 2, 62, 222
35 Pegfilgrastim 1件: Pegfilgrastim1件: D06889 1件: CSF3R 💬5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬1件: 60
36 Peginesatide 2件: Hematide; Peginesatide1件: D09946 1件: EPOR 💬5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬1件: 283
37 Peginterferon beta-1a 2件: PEGINTERFERON BETA-1A; Plegridy1件: D10483 2件: IFNAR1,
IFNAR2 💬
18件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬1件: 13
38 Pegsunercept 2件: Pegsunercept; STNF-R11件: D05393 1件: TNF 💬67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬1件: 46
39 Pegunigalsidase alfa 1件: PEGUNIGALSIDASE ALFA1件: D11685 --1件: 19
40 Pegvaliase 3件: Palynziq; PEGVALIASE; RAvPAL-PEG1件: D11077 1件: PAH 💬5件: Biosynthesis of amino acids, Folate biosynthesis, Metabolic pathways, Phenylalanine metabolism, Phenylalanine, tyrosine and tryptophan biosynthesis 💬1件: 240
41 Pegvisomant 1件: Pegvisomant1件: D05394 1件: GHR 💬5件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬1件: 78
42 Pelubiprofen 1件: Pelubiprofen1件: D01865 --1件: 46
43 Pemafibrate 1件: Pemafibrate1件: D10711 1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬1件: 93
44 Pembrolizumab 1件: Pembrolizumab1件: D10574 1件: PDCD1 💬3件: Cell adhesion molecules, PD-L1 expression and PD-1 checkpoint pathway in cancer, T cell receptor signaling pathway 💬2件: 25, 285
45 Pemirolast 1件: PEMIROLAST2件: D01088 ,
D07476
--1件: 113
46 Penciclovir 0件: 2件: D02124 ,
D05407
--1件: 13
47 Penicillamine 2件: D-penicillamine; Penicillamine1件: D00496 --2件: 51, 171
48 Pentamidine 2件: Pentamidina; Pentamidine2件: D00834 ,
D08333
--2件: 61, 65
49 Pentetic acid 1件: DTPA1件: D05422 --2件: 28, 299
50 Pentetreotide 1件: Pentetreotide1件: D01859 --1件: 75
51 Pentosan polysulfate 1件: Pentosan polysulfate1件: D05428 --3件: 19, 26, 226
52 Pentoxifylline 1件: Pentoxifylline1件: D00501 --10件: 26, 56, 84, 93, 96, 113, 220, 222, 296, 298
53 Peppermint 1件: Peppermint1件: D05431 --1件: 226
54 Peppermint oil 1件: Peppermint oil1件: D05432 --1件: 226
55 Perampanel 2件: Fycompa; Perampanel1件: D08964 4件: GRIA1,
GRIA2,
GRIA3,
GRIA4 💬
16件: Amphetamine addiction, Amyotrophic lateral sclerosis, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Transcriptional misregulation in cancer, cAMP signaling pathway 💬3件: 2, 6, 144
56 Perflubutane 1件: Perflubutane1件: D05440 --2件: 298, 300
57 Perflutren 1件: Optison1件: D01738 --1件: 96
58 Pergolide 1件: PERGOLIDE2件: D00502 ,
D08339
2件: DRD1,
DRD2 💬
11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6
59 Perhexiline 1件: Perhexiline2件: D05442 ,
D08340
8件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
CPT1A,
CPT1B,
CPT1C,
CPT2 💬
47件: AMPK signaling pathway, Adipocytokine signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholic liver disease, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Dilated cardiomyopathy, Dopaminergic synapse, Fatty acid degradation, Fatty acid metabolism, GABAergic synapse, Glucagon signaling pathway, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin resistance, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, PPAR signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Thermogenesis, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 58, 272
60 Perindopril 2件: Coversyl; Perindopril2件: D00624 ,
D03753
1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬4件: 58, 113, 167, 222
61 Pertussis vaccine 1件: Pertussis vaccine1件: D06514 --2件: 13, 46
62 Petrolatum 1件: Petrolatum1件: D05331 --3件: 35, 158, 162
63 Pexidartinib 1件: Turalio1件: D11270 3件: CSF1R,
FLT3,
KIT 💬
15件: Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Transcriptional misregulation in cancer, Viral protein interaction with cytokine and cytokine receptor 💬1件: 34
64 PF-00489791 1件: PF-00489791---1件: 86
65 PF-06650833 1件: PF-06650833---1件: 46
66 PF-06651600 1件: PF-06651600---3件: 46, 96, 97
67 PF-06700841 1件: PF-06700841---3件: 49, 96, 97
68 Pfizer-BioNTech COVID-19 Vaccine 2件: Comirnaty; Tozinameran1件: D11971 --5件: 13, 46, 51, 53, 299
69 PH-797804 1件: PH-797804---1件: 46
70 Phenelzine 1件: Nardil2件: D00505 ,
D08349
2件: MAOA,
MAOB 💬
14件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬1件: 6
71 Phenindione 0件: 1件: D08354 1件: VKORC1 💬3件: Biosynthesis of cofactors, Metabolic pathways, Ubiquinone and other terpenoid-quinone biosynthesis 💬1件: 65
72 Phenothiazine 1件: Phenothiazine1件: D02601 --1件: 127
73 Phenoxymethylpenicillin 0件: 3件: D00497 ,
D02506 ,
D05411
--3件: 13, 97, 215
74 Phentermine 1件: Phentermine2件: D05458 ,
D05459
5件: MAOA,
MAOB,
SLC6A2,
SLC6A3,
SLC6A4 💬
16件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Phenylalanine metabolism, Serotonergic synapse, Synaptic vesicle cycle, Tryptophan metabolism, Tyrosine metabolism 💬1件: 97
75 Phenylalanine 1件: Phenylalanine1件: D00021 --2件: 75, 240
76 Phenylbutyric acid 4件: 4-phenylbutyrate; Pheburane; Phenylbutyrate; Sodium Phenylbutyrate---14件: 2, 3, 6, 8, 15, 21, 93, 94, 231, 244, 251, 297, 299, 338
77 Phenylephrine 1件: Phenylephrine2件: D00511 ,
D08365
3件: ADRA1A,
ADRA1B,
ADRA1D 💬
7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 22
78 Phenytoin 1件: Phenytoin2件: D00512 ,
D02103
5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬
3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬1件: 13
79 Phosphate ion 1件: Phosphate---33件: 2, 3, 6, 11, 12, 13, 15, 28, 36, 46, 49, 51, 53, 60, 62, 65, 70, 78, 81, 83, 90, 96, 97, 164, 235, 238, 256, 276, 283, 284, 285, 286, 299
80 Phosphatidyl serine 0件: 1件: D04682 --4件: 6, 46, 90, 97
81 Phosphorus 2件: Phosphorous; Phosphorus---3件: 8, 58, 238
82 Phosphorus P-32 0件: ---1件: 37
83 Phylloquinone 4件: Phylloquinone; Phytomenadione; Vitamin K; Vitamin K11件: D00148 --6件: 13, 46, 96, 97, 288, 299
84 PI-0824 1件: PI-0824---1件: 35
85 Piclidenoson 1件: Piclidenoson1件: D10971 1件: ADORA3 💬3件: Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬1件: 46
86 Piclozotan 1件: Piclozotan---1件: 6
87 Picosulfuric acid 1件: Picosulfate---2件: 97, 291
88 Pidolic acid 0件: ---2件: 46, 70
89 Pilocarpine 2件: Pilocarpine; Pilocarpine Hydrochloride3件: D00525 ,
D02200 ,
D05478
2件: CHRM2,
CHRM3 💬
13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬3件: 6, 53, 299
90 Pimavanserin 1件: Pimavanserin---1件: 6
91 Pimecrolimus 1件: Pimecrolimus1件: D05480 5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬
33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬1件: 160
92 Pimozide 1件: Pimozide1件: D00560 2件: ADRA2A,
DRD2 💬
9件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 2
93 Pioglitazone 1件: Pioglitazone2件: D00945 ,
D08378
1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
94 Piperacillin 1件: PIPERACILLIN3件: D00466 ,
D02251 ,
D08380
--1件: 299
95 Piperazine 1件: Piperazine6件: D00807 ,
D01393 ,
D02127 ,
D02145 ,
D05486 ,
D06224
--2件: 58, 272
96 Pirfenidone 2件: Esbriet; Pirfenidone1件: D01583 6件: CCL2,
IL10,
IL1A,
IL1B,
IL6,
TNF 💬
84件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemokine signaling pathway, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Staphylococcus aureus infection, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
97 Piribedil 1件: Piribedil1件: D07305 2件: DRD2,
DRD3 💬
8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6
98 Pitavastatin 1件: Pitavastatin---1件: 49
99 Pitolisant 1件: Pitolisant1件: D10749 1件: HRH3 💬1件: Neuroactive ligand-receptor interaction 💬3件: 6, 113, 193
100 Pittsburgh Compound B 2件: C-11 PiB; Pittsburgh Compound B---2件: 6, 127
101 Pixantrone 1件: PIXANTRONE1件: D05522 2件: TOP2A,
TOP2B 💬
1件: Platinum drug resistance 💬2件: 11, 13
102 Placental Mesenchymal Stem Cells 2件: Placental Mesenchymal Stem Cells; PLX-PAD---2件: 86, 118
103 Plantago seed 2件: Psyllium; Psyllium husk1件: D05525 --3件: 6, 28, 97
104 Plasma protein fraction (human) 1件: Octaplas---1件: 64
105 Pleconaril 1件: PLECONARIL1件: D05528 --1件: 2
106 Plerixafor 2件: Mozobil; Plerixafor1件: D08971 1件: CXCR4 💬12件: Axon guidance, Calcium signaling pathway, Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Intestinal immune network for IgA production, Leukocyte transendothelial migration, Pathways in cancer, Regulation of actin cytoskeleton, Viral protein interaction with cytokine and cytokine receptor 💬6件: 19, 20, 51, 65, 285, 299
107 Polaprezinc 1件: Polaprezinc1件: D01611 --2件: 96, 97
108 Polidocanol 1件: Polidocanol1件: D01993 --1件: 279
109 Poly(lactic acid) 1件: POLY-L-LACTIC ACID---1件: 265
110 Polyethylene glycol 4件: Macrogol; Macrogol 4000; Polyethylene glycol; Polyethylene Glycol 33501件: D03370 --14件: 6, 13, 41, 46, 65, 78, 96, 97, 140, 144, 235, 240, 276, 299
111 Pomalidomide 3件: Imnovid; Pomalidomida; Pomalidomide1件: D08976 2件: IL6,
TNF 💬
80件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬6件: 28, 34, 51, 85, 227, 331
112 Pomegranate 1件: Pomegranate---2件: 96, 97
113 Ponesimod 1件: PONESIMOD1件: D11215 1件: S1PR1 💬3件: FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬1件: 13
114 Poractant alfa 1件: Curosurf1件: D08402 --1件: 211
115 Porphobilinogen 1件: Porphobilinogen---1件: 254
116 Posaconazole 2件: Noxafil; POSACONAZOLE1件: D02555 --4件: 60, 65, 96, 299
117 Posiphen 1件: Posiphen---1件: 6
118 Potassium 1件: Potassium1件: D08403 --12件: 36, 46, 66, 67, 88, 94, 98, 115, 167, 179, 215, 235
119 Potassium carbonate 0件: 1件: D02038 --3件: 6, 96, 291
120 Pozelimab 1件: Pozelimab1件: D11477 1件: C5 💬10件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬2件: 11, 62
121 Pramipexole 7件: Mirapex; Mirapex ER; Mirapexin; Pramipexol; Pramipexole; PRAMIPEXOLE DIHYDROCHLORIDE; SIFROL2件: D00559 ,
D05575
3件: DRD2,
DRD3,
DRD4 💬
8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 2, 6, 20
122 Prasinezumab 1件: Prasinezumab1件: D11420 1件: SNCA 💬3件: Alzheimer disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬1件: 6
123 Prasterone 3件: Dehydroepiandrosterone; DHEA; Prasterone1件: D08409 3件: AR,
ESR1,
ESR2 💬
12件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Oocyte meiosis, Pathways in cancer, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬6件: 49, 53, 83, 86, 96, 113
124 Pravastatin 2件: Pravastatin; Pravastatin sodium2件: D00893 ,
D08410
1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬9件: 13, 46, 49, 67, 79, 96, 164, 265, 333
125 Prednisolone 3件: Prednisolona; Prednisolone; Prednisolonum8件: D00472 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01998 ,
D02156 ,
D03301
1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬43件: 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
126 Prednisolone acetate 1件: PREDNISOLONE ACETATE1件: D00980 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 222
127 Prednisone 3件: Prednisona; Prednisone; RAYOS1件: D00473 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬48件: 2, 6, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 127, 162, 164, 205, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331
128 Prednisone acetate 2件: Cortancyl; Prednisone Acetate1件: D08416 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬7件: 35, 40, 41, 46, 49, 162, 224
129 Pregabalin 2件: Lyrica; Pregabalin1件: D02716 4件: CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4 💬
7件: Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway 💬5件: 13, 36, 46, 70, 298
130 Preimplantation factor 2件: Preimplantation factor; Synthetic PreImplantation Factor---1件: 95
131 Preladenant 1件: Preladenant1件: D09717 1件: ADORA2A 💬7件: Alcoholism, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬1件: 6
132 Pridopidine 1件: Pridopidine1件: D09953 1件: DRD2 💬8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 2, 6, 8
133 PRM-151 1件: PRM-151---1件: 85
134 Probenecid 1件: Probenecid1件: D00475 --1件: 25
135 Probucol 1件: Probucol1件: D00476 --1件: 66
136 Procarbazine 1件: Procarbazine2件: D00478 ,
D08423
--1件: 65
137 Progesterone 1件: Progesterone1件: D00066 1件: PGR 💬5件: Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬1件: 76
138 Proline 1件: Proline1件: D00035 --2件: 94, 97
139 Promethazine 1件: Promethazine4件: D00480 ,
D00494 ,
D01242 ,
D03290
1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬1件: 96
140 Propanoic acid 1件: Propanoic acid1件: D02310 --2件: 6, 271
141 Propantheline 2件: Propantheline; Propantheline Bromide1件: D00481 5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬
13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬1件: 26
142 Propiverine 1件: Propiverine1件: D08441 9件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬
43件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Regulation of actin cytoskeleton, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 226
143 Propofol 2件: Propofol; Propofol Injection1件: D00549 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬
7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬10件: 6, 21, 22, 34, 46, 70, 75, 84, 98, 296
144 Propranolol 3件: Propanolol; Propranolol; Propranolol Hydrochloride2件: D00483 ,
D08443
3件: ADRB1,
ADRB2,
ADRB3 💬
12件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬7件: 6, 158, 167, 215, 227, 278, 296
145 Propylene glycol 1件: Propylene glycol1件: D00078 --2件: 28, 51
146 Prothrombin 1件: Prothrombin---1件: 288
147 Protirelin 1件: Thyrotropin releasing hormone1件: D00176 1件: TRHR 💬2件: Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬1件: 80
148 Prucalopride 2件: PRUCALOPRIDE; Resolor1件: D09205 1件: HTR4 💬4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Serotonergic synapse, cAMP signaling pathway 💬3件: 13, 51, 96
149 Pseudoephedrine 1件: Pseudoephedrine4件: D00485 ,
D05648 ,
D05649 ,
D08449
9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬
14件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 17
150 Psilocybin 2件: Psilocybin; Psilocybine---1件: 6
151 PTC299 1件: PTC299---1件: 34
152 PTI-428 1件: PTI-428---1件: 299
153 PTI-801 1件: PTI-801---1件: 299
154 Puerarin 1件: Puerarin---1件: 46
155 Pyrazole 2件: 1H-Pyrazol; Pyrazole---6件: 2, 28, 46, 58, 75, 154
156 Pyridostigmine 3件: Mestinon; PYRIDOSTIGMINE; PYRIDOSTIGMINE BROMIDE1件: D00487 1件: ACHE 💬2件: Cholinergic synapse, Glycerophospholipid metabolism 💬4件: 3, 6, 11, 256
157 Pyridoxal phosphate 0件: 1件: D00006 --1件: 13
158 Pyridoxine 2件: Pyridoxine; Vitamin B62件: D02179 ,
D08454
--5件: 6, 93, 145, 206, 320
159 Pyrimethamine 2件: Daraprim; PYRIMETHAMINE1件: D00488 --11件: 2, 4, 6, 13, 19, 46, 51, 65, 96, 97, 265