Drug Description in Trials / DrugBank / KEGG DRUG


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No. DrugBank 薬物名(臨床試験情報から抽出) KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes
指定難病告示番号
1 L-Glutamine 2件: Glutamine; L-Glutamine1件: D00015 --7件: 87, 89, 96, 97, 113, 245, 299
2 L-Lactic acid 2件: L-Lactic acid; Lactic acid---1件: 265
3 Lacosamide 1件: Lacosamide1件: D07299 2件: SCN3A,
SCN9A 💬
1件: Taste transduction 💬3件: 2, 46, 149
4 Lactic acid 1件: Lactic acid1件: D00111 --2件: 265, 299
5 Lactobacillus acidophilus 2件: Acidophilus; Lactobacillus1件: D04349 --1件: 97
6 Lactobacillus casei 2件: Fusion; Lactobacillus casei1件: D04351 --10件: 6, 11, 13, 46, 49, 69, 70, 97, 271, 296
7 Lactobacillus delbrueckii bulgaricus 1件: Lactobacillus---5件: 6, 46, 51, 97, 299
8 Lactobacillus plantarum 1件: Lactobacillus plantarum---3件: 6, 97, 156
9 Lactobacillus reuteri 1件: LACTOBACILLUS REUTERI---2件: 97, 299
10 Lactobacillus salivarius 1件: Lactobacillus salivarius---2件: 96, 97
11 Lactose 1件: Lactose2件: D00046 ,
D03226
--6件: 2, 6, 13, 97, 228, 310
12 Lactulose 1件: Lactulose1件: D00352 --3件: 13, 96, 291
13 Ladarixin 1件: Ladarixin---1件: 162
14 Lamivudine 4件: COMBIVIR; Epivir; Lamivudine; Triumeq1件: D00353 --7件: 2, 26, 42, 46, 135, 265, 325
15 Lamotrigine 2件: Lamictal; LAMOTRIGINE1件: D00354 5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬
3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬5件: 13, 34, 38, 114, 144
16 Lancovutide 1件: DURAMYCIN---1件: 299
17 Lanifibranor 1件: LANIFIBRANOR---1件: 51
18 Lanraplenib 1件: Lanraplenib1件: D11596 --2件: 53, 222
19 Lanreotide 3件: Lanreotide; LANREOTIDE ACETATE; Somatuline Autogel---4件: 67, 73, 85, 298
20 Lansoprazole 1件: Lansoprazole1件: D00355 2件: ATP4A,
ATP4B 💬
4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬7件: 63, 71, 85, 98, 166, 222, 299
21 Lapaquistat 1件: Lapaquistat---1件: 79
22 Lapatinib 1件: Lapatinib2件: D04024 ,
D08108
2件: EGFR,
ERBB2 💬
50件: Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Platinum drug resistance, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Tight junction 💬3件: 34, 74, 75
23 Laquinimod 1件: LAQUINIMOD---4件: 8, 13, 49, 96
24 Laronidase 2件: Aldurazyme; Laronidase1件: D04670 1件: IDUA 💬3件: Glycosaminoglycan degradation, Lysosome, Metabolic pathways 💬2件: 19, 256
25 Latrepirdine 2件: Dimebon; Latrepirdine1件: D09917 6件: ACHE,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬
22件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬1件: 8
26 LAX-101 1件: LAX-101---1件: 8
27 Lebrikizumab 1件: LEBRIKIZUMAB1件: D09633 1件: IL13 💬8件: Asthma, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, IL-17 signaling pathway, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation 💬1件: 85
28 Lecithin 1件: Phosphatidylcholine1件: D04682 --1件: 97
29 Ledipasvir 2件: Harvoni; Ledipasvir1件: D10442 --2件: 19, 254
30 Lefamulin 1件: Lefamulin1件: D11631 --1件: 299
31 Leflunomide 3件: Arava; Leflunomide; Leflunomidum1件: D00749 1件: DHODH 💬3件: Biosynthesis of cofactors, Metabolic pathways, Pyrimidine metabolism 💬12件: 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300
32 Lenalidomide 2件: Lenalidomide; REVLIMID1件: D04687 1件: TNF 💬67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬8件: 16, 26, 28, 34, 49, 284, 300, 331
33 Leniolisib 1件: Leniolisib1件: D11158 3件: PIK3CA,
PIK3CB,
PIK3CD 💬
106件: AGE-RAGE signaling pathway in diabetic complications, AMPK signaling pathway, Acute myeloid leukemia, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Amoebiasis, Apoptosis, Autophagy - animal, Axon guidance, B cell receptor signaling pathway, Bacterial invasion of epithelial cells, Breast cancer, C-type lectin receptor signaling pathway, Carbohydrate digestion and absorption, Cellular senescence, Central carbon metabolism in cancer, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, Epstein-Barr virus infection, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gastric cancer, Glioma, GnRH secretion, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Inflammatory mediator regulation of TRP channels, Influenza A, Inositol phosphate metabolism, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leukocyte transendothelial migration, Lipid and atherosclerosis, Longevity regulating pathway, Longevity regulating pathway - multiple species, Measles, Melanoma, Metabolic pathways, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Phosphatidylinositol signaling system, Phospholipase D signaling pathway, Platelet activation, Platinum drug resistance, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Small cell lung cancer, Sphingolipid signaling pathway, Spinocerebellar ataxia, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, Type II diabetes mellitus, VEGF signaling pathway, Viral carcinogenesis, Yersinia infection, cAMP signaling pathway, mTOR signaling pathway 💬2件: 53, 65
34 Lenograstim 2件: G-CSF; Lenograstim1件: D03247 1件: CSF3R 💬5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬7件: 2, 13, 16, 18, 19, 57, 65
35 Lenomorelin 1件: Ghrelin---6件: 6, 78, 193, 201, 202, 299
36 Leptin 1件: Leptin---2件: 6, 265
37 Leriglitazone 1件: Leriglitazone1件: D11603 1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬1件: 20
38 Letermovir 1件: Letermovir1件: D10801 --1件: 85
39 Letrozole 1件: Letrozole1件: D00964 1件: CYP19A1 💬3件: Metabolic pathways, Ovarian steroidogenesis, Steroid hormone biosynthesis 💬2件: 81, 89
40 Leucine 2件: L-leucine; Leucine1件: D00030 --11件: 5, 6, 7, 19, 65, 96, 97, 127, 283, 284, 299
41 Leucovorin 2件: Folinic acid; Leucovorin3件: D01211 ,
D07986 ,
D07987
--4件: 19, 46, 107, 320
42 Leuprolide 2件: Leuprolide; Leuprorelin1件: D00989 1件: GNRHR 💬2件: GnRH signaling pathway, Neuroactive ligand-receptor interaction 💬5件: 1, 2, 3, 51, 76
43 Levamisole 1件: Levamisole2件: D00750 ,
D08114
--3件: 60, 61, 62
44 Levetiracetam 2件: KEPPRA; Levetiracetam1件: D00709 1件: SV2A 💬1件: ECM-receptor interaction 💬5件: 2, 4, 6, 13, 307
45 Levobupivacaine 2件: Bupivacaine; Levobupivacaine2件: D01287 ,
D08116
5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬
3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬1件: 46
46 Levocarnitine 4件: Carnitine; L-Carnitine; Levocarnitine; Xyzal3件: D02030 ,
D02176 ,
D04713
--11件: 3, 5, 13, 53, 58, 86, 96, 97, 265, 298, 316
47 Levocarnitine propionate 1件: Propionyl-L-Carnitine---1件: 97
48 Levocetirizine 1件: Levocetirizina1件: D07402 1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬1件: 61
49 Levodopa 8件: DUODOPA; Inbrija; L-DOPA; LEVODOPA; PARCOPA; SINEMET; SINEMET CR; Stalevo1件: D00059 5件: DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬
11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬8件: 2, 4, 6, 17, 90, 140, 164, 201
50 Levofloxacin 2件: Levaquin; Levofloxacin2件: D00588 ,
D08120
--5件: 46, 53, 84, 85, 299
51 Levoketoconazole 1件: Levoketoconazole1件: D10950 --1件: 75
52 Levoleucovorin 1件: Levofolene---1件: 13
53 Levomefolic acid 1件: L-methylfolate1件: D09353 --1件: 6
54 Levonorgestrel 1件: LEVONORGESTREL1件: D00950 1件: PGR 💬5件: Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬1件: 13
55 Levosalbutamol 2件: R-salbutamol; Salbutamol1件: D08124 1件: ADRB2 💬9件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 49
56 Levosimendan 1件: LEVOSIMENDAN1件: D04720 2件: PDE3A,
PDE3B 💬
11件: Apelin signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 2
57 Levothyroxine 3件: Levothyroxine; Thyroid; Thyroxine2件: D01010 ,
D08125
2件: THRA,
THRB 💬
2件: Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬5件: 19, 49, 78, 80, 222
58 Liatermin 2件: Liatermin; R-metHuGDNF1件: D04727 --1件: 6
59 Licorice 2件: Licorice; Liquorice1件: D04365 --2件: 53, 83
60 Lidocaine 4件: Aloe; Lidocaine; Lignocaine; Xylocaine3件: D00358 ,
D02086 ,
D08127
5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬
3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬13件: 6, 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256
61 Limaprost 1件: Limaprost1件: D02722 1件: PTGER1 💬4件: Calcium signaling pathway, Human cytomegalovirus infection, Neuroactive ligand-receptor interaction, Pathways in cancer 💬1件: 70
62 Linaclotide 1件: Linaclotide1件: D09355 1件: GUCY2C 💬2件: Metabolic pathways, Purine metabolism 💬2件: 6, 97
63 Linezolid 1件: LINEZOLID1件: D00947 --1件: 299
64 Linoleic acid 1件: Linoleic acid---8件: 2, 5, 6, 13, 75, 76, 222, 299
65 Linsitinib 1件: Linsitinib1件: D09925 1件: IGF1R 💬29件: AMPK signaling pathway, Adherens junction, Autophagy - animal, Breast cancer, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Focal adhesion, FoxO signaling pathway, Glioma, HIF-1 signaling pathway, Hepatocellular carcinoma, Long-term depression, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Melanoma, Oocyte meiosis, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, mTOR signaling pathway 💬1件: 232
66 Liothyronine 4件: Liothyronine; Liothyronine sodium; Thyroid; Triiodothyronine2件: D01011 ,
D08128
2件: THRA,
THRB 💬
2件: Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬4件: 13, 78, 210, 212
67 Liothyronine I-131 1件: Liothyronine I 131---2件: 210, 212
68 Lipoic acid 3件: Alpha Lipoic Acid; ALPHA-LIPOIC ACID; Lipoic acid2件: D00048 ,
D00086
--5件: 2, 5, 13, 14, 20
69 Liraglutide 2件: Liraglutide; Saxenda1件: D06404 1件: GLP1R 💬3件: Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬3件: 6, 75, 193
70 Lirentelimab 1件: Lirentelimab1件: D11906 --1件: 98
71 Lisdexamfetamine 1件: Lisdexamfetamine1件: D08130 2件: SLC6A2,
SLC6A3 💬
7件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬1件: 13
72 Lisinopril 2件: LISINOPRIL; ZESTRIL2件: D00362 ,
D08131
1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬7件: 19, 46, 49, 66, 67, 113, 222
73 Lisuride 1件: LISURIDE2件: D01462 ,
D08132
3件: DRD2,
DRD3,
DRD4 💬
8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬2件: 6, 86
74 Lithium carbonate 2件: Lithium; Lithium Carbonate1件: D00801 --6件: 2, 13, 17, 18, 19, 127
75 Lithium citrate 2件: Lithium; LITHIUM CITRATE1件: D04749 --5件: 2, 5, 6, 7, 8
76 Livoletide 1件: Livoletide---1件: 193
77 Lixisenatide 1件: Lixisenatide1件: D09729 1件: GLP1R 💬3件: Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬1件: 6
78 Lixivaptan 1件: Lixivaptan1件: D04752 1件: AVPR2 💬3件: Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬1件: 67
79 Lomitapide 2件: Lojuxta; LOMITAPIDE1件: D09637 1件: MTTP 💬1件: Fat digestion and absorption 💬1件: 79
80 Lonafarnib 1件: Lonafarnib1件: D04768 2件: FNTA,
FNTB 💬
1件: Terpenoid backbone biosynthesis 💬2件: 113, 333
81 Lonapegsomatropin 1件: LONAPEGSOMATROPIN1件: D11486 1件: GHR 💬5件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬1件: 78
82 Loperamide 2件: LOPERAMIDE; Loperamide hydrochloride3件: D00729 ,
D07113 ,
D08144
3件: OPRD1,
OPRK1,
OPRM1 💬
5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬2件: 13, 97
83 Lopinavir 2件: Kaletra; Lopinavir1件: D01425 --2件: 93, 265
84 Loratadine 2件: Loratadina; Loratadine1件: D00364 1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬4件: 13, 46, 89, 98
85 Lorazepam 1件: Lorazepam1件: D00365 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬
7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬2件: 36, 231
86 Lorcaserin 1件: Lorcaserin---1件: 140
87 Losartan 3件: Cozaar; Losartan; LOSARTAN POTASSIUM2件: D00357 ,
D08146
1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
88 Losmapimod 1件: Losmapimod1件: D09639 4件: MAPK11,
MAPK12,
MAPK13,
MAPK14 💬
62件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Alcoholic liver disease, Amyotrophic lateral sclerosis, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Dopaminergic synapse, Endocrine resistance, Epithelial cell signaling in Helicobacter pylori infection, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hepatitis B, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, IL-17 signaling pathway, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Leukocyte transendothelial migration, Lipid and atherosclerosis, MAPK signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Oocyte meiosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Platelet activation, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rap1 signaling pathway, Relaxin signaling pathway, Retrograde endocannabinoid signaling, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thermogenesis, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Yersinia infection 💬2件: 113, 222
89 Lovastatin 1件: Lovastatin1件: D00359 1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬11件: 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310
90 Loxoprofen 1件: Loxoprofen1件: D08149 2件: PTGS1,
PTGS2 💬
23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬2件: 46, 271
91 Lubiprostone 1件: Lubiprostone1件: D04790 1件: CLCN2 💬1件: Mineral absorption 💬4件: 6, 13, 290, 299
92 Lucerastat 1件: Lucerastat1件: D11439 1件: UGCG 💬2件: Metabolic pathways, Sphingolipid metabolism 💬1件: 19
93 Lucinactant 1件: Lucinactant1件: D04792 --1件: 299
94 Lulizumab pegol 2件: BMS-931699; Lulizumab Pegol---3件: 49, 53, 160
95 Lumacaftor 2件: LUMACAFTOR; Orkambi1件: D10134 1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
96 Lumasiran 1件: LUMASIRAN1件: D11925 1件: HAO1 💬4件: Carbon metabolism, Glyoxylate and dicarboxylate metabolism, Metabolic pathways, Peroxisome 💬1件: 234
97 Lumiracoxib 1件: Lumiracoxib1件: D03714 1件: PTGS2 💬22件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 46
98 Lunasine 1件: Lunasin---1件: 2
99 Lutein 1件: Lutein---3件: 13, 90, 164
100 Luteinizing hormone 1件: Luteinizing hormone---1件: 254
101 Lysergic acid diethylamide 0件: ---1件: 271
102 Lysine 1件: Lysine1件: D02304 --5件: 13, 19, 97, 228, 299